Chelidonic acid

製品コードS5579 バッチS557901

印刷

化学情報

Chemical Structure Synonyms Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid Storage
(From the date of receipt)		 3 years -20°C powder
化学式

C7H4O6
分子量 184.10 CAS No. 99-32-1
Solubility (25°C)* 体外 DMSO 4 mg/mL (21.72 mM)
 
 
体内 （毎回新しく調製した物を用意してください）
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明 Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid) is a secondary metabolite found in several plants with therapeutic potential in allergic disorders in experimental animals. Chelidonic acid inhibits IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells. Chelidonic acid is also an inhibitor of glutamate decarboxylase with Ki of 1.2 μM.
in vitro Chelidonic acid (also known as chelidonate) is a heterocyclic organic acid. It is a solid with a melting point between 158-160 °C and is soluble in hot water. This compound forms a dihydrate and can be synthesized through various methods, including the oxidation of chelidonine. This chemical exhibits tautomerism and has been studied for its potential biological activities.
in vivo Chelidonic acid (also known as chelidonate) is a heterocyclic organic acid. It is a solid with a melting point between 152–153 °C. This compound is classified as an γ-pyrone, a type of compound where a ketone is attached to a carbon-carbon double bond within a six-membered ring. This chemical is found in several plant species, notably in the greater celandine (Chelidonium majus). The molecule can serve as a ligand in coordination chemistry.

プロトコル(参考用のみ)

キナーゼアッセイ
細胞アッセイ 細胞株
濃度
反応時間
実験の流れ Chelidonic acid (also known as chelidonate) is a heterocyclic organic acid. It is a strong dicarboxylic acid with the molecular formula C7H4O6. This compound is found in several plants, particularly in the greater celandine (Chelidonium majus). This chemical can serve as a building block in organic synthesis. The structure of this compound features a pyran ring. It is known for its chelating properties.
動物実験 動物モデル
投薬量
投与方法

参考

  • https://pubmed.ncbi.nlm.nih.gov/21320026/
  • https://pubmed.ncbi.nlm.nih.gov/4062982/

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

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