CP21R7

製品コードS7954 バッチS795401

印刷

化学情報

Synonyms

CP21

Storage
(From the date of receipt)

3 years -20°C powder
1 years -80°C in solvent

化学式

C₁₉H₁₅N₃O₂

分子量

317.34

CAS No.

125314-13-8

Solubility (25°C)*

体外

DMSO

63 mg/mL (198.52 mM)

Ethanol (warmed with 50ºC water bath)

1 mg/mL (3.15 mM)

Water

Insoluble

体内（毎回新しく調製した物を用意してください）

Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O この製剤はselleckのラボで検証済みです。上記の溶解方法がご要望を満たさない場合、selleckの営業担当までお問い合わせ頂ければ、個別の試験を行います。	3.150mg/ml (9.93mM)	Taking the 1 mL working solution as an example, add 50 μL of 63 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil この製剤はselleckのラボで検証済みです。上記の溶解方法がご要望を満たさない場合、selleckの営業担当までお問い合わせ頂ければ、個別の試験を行います。	0.390mg/ml (1.23mM)	Taking the 1 mL working solution as an example, add 50 μL of 7.8 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	CP21R7 is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling.

プロトコル(参考用のみ)

参考

https://pubmed.ncbi.nlm.nih.gov/20138512/

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing [ J Nanobiotechnology, 2024, 22(1):373]	PubMed: 38926800
Patient-derived rhabdomyosarcoma cells recapitulate the genetic and transcriptomic landscapes of primary tumors [ iScience, 2024, 27(10):110862]	PubMed: 39319271
A highly efficient, scalable pipeline for fixed feature extraction from large-scale high-content imaging screens [ iScience, 2024, 27(12):111434]	PubMed: 39720532
Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses [ Cell, 2022, 185(14):2523-2541.e30]	PubMed: 35738284
Establishment and characterization of immortalized sweat gland myoepithelial cells [ Sci Rep, 2022, 12(1):7]	PubMed: 34997030
Nanoprotein Interaction Atlas Reveals the Transport Pathway of Gold Nanoparticles across Epithelium and Its Association with Wnt/β-Catenin Signaling [ ACS Nano, 2021, 10.1021/acsnano.1c06452]	PubMed: 34672537
Endothelial Progenitor Cells Produced From Human Pluripotent Stem Cells by a Synergistic Combination of Cytokines, Small Compounds, and Serum-Free Medium [ Front Cell Dev Biol, 2020, 15;8:309]	PubMed: 32509776
Gastric-cancer-derived Mesenchymal Stem Cells: A Promising Target for Resveratrol in the Suppression of Gastric Cancer Metastasis [ Hum Cell, 2020, 29]	PubMed: 32350750
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling [ Cancer Manag Res, 2020, 12:11773-11782]	PubMed: 33235505
Activation of Wnt/β-catenin Pathway Causes Insulin Resistance and Increases Lipogenesis in HepG2 Cells via Regulation of Endoplasmic Reticulum Stress [ Biochem Biophys Res Commun, 2020, 4;526(3):764-771]	PubMed: 32265032

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。