D-(+)-Trehalose dihydrate

製品コードS3992 バッチS399201

化学情報

	Synonyms	N/A	Storage (From the date of receipt)	3 years -20°C powder 1 years -80°C in solvent
	化学式	C₁₂ H₂₂O_{11 . 2}H₂O
	分子量	378.33	CAS No.	6138-23-4
Solubility (25°C)*	体外	Water	76 mg/mL (200.88 mM)
		DMSO	75 mg/mL (198.23 mM)

* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.
in vitro	Trehalose has been shown to play a key role in various types of stress-tolerance including radiation, cold and dehydration stresses in bacteria, yeast, nematodes, rotifers, tardigrades, certain crustaceans and insects. Studies on the role of trehalose in stress-tolerance suggest that trehalose must be presence on both sides of the cell membrane to confer protection. It is a non-charged and hydrophilic disaccharide which does not freely penetrate the mammalian cell membrane without external interventions^[1].

製品説明

Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.

in vitro

Trehalose has been shown to play a key role in various types of stress-tolerance including radiation, cold and dehydration stresses in bacteria, yeast, nematodes, rotifers, tardigrades, certain crustaceans and insects. Studies on the role of trehalose in stress-tolerance suggest that trehalose must be presence on both sides of the cell membrane to confer protection. It is a non-charged and hydrophilic disaccharide which does not freely penetrate the mammalian cell membrane without external interventions^[1].

プロトコル(参考用のみ)

参考

[1] Alireza Abazari, et al. PLoS One. 2015, 10(6): e0130323.

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Ovatodiolide induces autophagy-mediated cell death through the p62-Keap1-Nrf2 signaling pathway in chronic myeloid leukemia cells [ Chem Biol Interact, 2023, 10.1016/j.cbi.2023.110819]	PubMed: 38000454
Solubility enhancement of BCS Class II drug by solid phospholipid dispersions: Spray drying versus freeze-drying. [ Int J Pharm, 2015, 496(2):382-91]	PubMed: 26468038

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。