DFO

製品コードS6849 バッチS684901

印刷

化学情報

Chemical Structure Synonyms 9H-1,8-Diazafluoren-9-one, 1,8-Diazafluoren-9-one Storage
(From the date of receipt)		 3 years -20°C powder
化学式

C11H6N2O
分子量 182.18 CAS No. 54078-29-4
Solubility (25°C)* 体外 DMSO 36 mg/mL (197.6 mM)
Water 2 mg/mL (10.97 mM)
Ethanol Insoluble
体内 （毎回新しく調製した物を用意してください）
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明 DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids.

プロトコル(参考用のみ)

参考

  • https://pubmed.ncbi.nlm.nih.gov/26254628/

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Tetrahydromagnolol induces autophagic cell death by targeting the m6A reader protein YTHDF2 and enhances the efficacy of anti-PD-1 immunotherapy in pancreatic cancer cells [ Theranostics, 2025, 15(15):7726-7746] PubMed: 40756353
Exosomal miR-375-3p mediated lipid metabolism, ferritinophagy and CoQ-dependent pathway contributes to the ferroptosis of keratinocyte in SJS/TEN [ Int J Biol Sci, 2025, 21(3):1275-1293] PubMed: 39897035
NFAT5 exacerbates β-cell ferroptosis by suppressing the transcription of PRDX2 in obese type 2 diabetes mellitus [ Cell Mol Life Sci, 2025, 82(1):64] PubMed: 39875646
Kinsenoside Suppresses DGAT1-Mediated Lipid Droplet Formation to Trigger Ferroptosis in Triple-Negative Breast Cancer [ Int J Mol Sci, 2025, 26(5)2322] PubMed: 40076939
BSA-stabilized selenium nanoparticles ameliorate intracerebral hemorrhage's-like pathology by inhibiting ferroptosis-mediated neurotoxicology via Nrf2/GPX4 axis activation [ Redox Biol, 2024, 75:103268] PubMed: 39032396
TRIB3 promotes malignancy of head and neck squamous cell carcinoma via inhibiting ferroptosis [ Cell Death Dis, 2024, 15(3):178] PubMed: 38429254
Selective PI3Kδ inhibitor TYM-3-98 suppresses AKT/mTOR/SREBP1-mediated lipogenesis and promotes ferroptosis in KRAS-mutant colorectal cancer [ Cell Death Dis, 2024, 15(7):474] PubMed: 38956060
Deferoxamine topical cream superior to patch in rescuing radiation-induced fibrosis of unwounded and wounded skin [ J Cell Mol Med, 2024, 28(8):e18306] PubMed: 38613357
Pivotal Role of GSTO2 in Ferroptotic Neuronal Injury After Intracerebral Hemorrhage [ J Mol Neurosci, 2024, 74(1):24] PubMed: 38386166
Overburdened ferroptotic stress impairs tooth morphogenesis [ Elife, 2023, 12RP88745] PubMed: 37991825

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。