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Disitamab vedotin
製品コード：D4049 Batch: D404901
Disitamab Vedotin (RC-48 ,RC 480-ADC) is an antibody-drug conjugate(ADC) composed of anti-[ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)] humanized monoclonal antibody, conjugated to monomethylauristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Disitamab Vedotin has the potential for use in solid tumors mainly in advanced breast cancer.
製品説明
| CAS No. | 2136633-23-1 |
|---|---|
| Formulation | 1xPBS |
| DAR | 3.8 |
| ADC antiody | Disitamab |
| ADC cytotoxin | MMAE |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
| Shipping | Shipped under low temperature conditions |
| Purity | 99.17% |
| Protein concentration | 3.3mg/ml |
| Endotoxin Level | ＜1EU/mg |
人間や獣医の診断であるか治療的な使用のためにでない。