Disitamab vedotin

製品コード：D4049         Batch: D404901

印刷

Disitamab Vedotin (RC-48 ,RC 480-ADC) is an antibody-drug conjugate(ADC) composed of anti-[ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)] humanized monoclonal antibody, conjugated to monomethylauristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Disitamab Vedotin has the potential for use in solid tumors mainly in advanced breast cancer.

製品説明

CAS No. 2136633-23-1
Formulation 1xPBS
DAR 3.8
ADC antiody Disitamab
ADC cytotoxin MMAE
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Shipping Shipped under low temperature conditions
Purity 99.17%
Protein concentration 3.3mg/ml
Endotoxin Level ＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

TNF Signaling Pathway Is the Key Pathway Regulated by Disitamab Vedotin in Bladder Cancer Cells [ Curr Issues Mol Biol, 2025, 47(5)369] PubMed: 40699768

人間や獣医の診断であるか治療的な使用のためにでない。