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製品コード:A2034 Batch: A203401
Elotuzumab (anti-SLAMF7, BMS-901608, PDL063, HuLuc63) is a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7, also known as CS1, CD319, or CRACC). Elotuzumab shows a dual mechanism of action that includes the direct activation of natural killer (NK) cells and the induction of NK cell–mediated antibody-dependent cellular cytotoxicity.
CAS No. | 915296-00-3 |
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Formulation | PBS Buffer, PH 7.4 |
Isotype | Human IgG1, κ |
Source | CHO cells |
Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
Shipping | Shipped under low temperature conditions |
Purity | 98% |
Protein concentration | 4.7 mg/ml |
Endotoxin Level | <1 EU/mg |
Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma [ Nat Commun, 2024, 15(1):1367] | PubMed: 38355622 |
人間や獣医の診断であるか治療的な使用のためにでない。