Evolocumab (anti-PCSK9)

製品コード：A2043         Batch: A204302

印刷

Evolocumab (anti-PCSK9) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR. Evolocumab can be used for the research of hypercholesterolemia and atherosclerotic cardiovascular diseases.

製品説明

CAS No. 1256937-27-5
Formulation PBS Buffer, PH 7.4
Isotype Human IgG2
Application Evolocumab (anti-PCSK9)
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Shipping Shipped under low temperature conditions
Purity 99%
Protein concentration 6.47mg/ml
Endotoxin Level <1 EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

A closed-loop cholesterol shunt controlling experimental dyslipidemia [ Cell Metab, 2025, 37(10):2066-2075.e3] PubMed: 40972574
BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity [ Cell Rep, 2025, 44(4):115493] PubMed: 40178982
PCSK9 inhibitors ameliorate arterial stiffness in ACS patients: evidences from Mendelian randomization, a retrospective study and basic experiments [ Front Med (Lausanne), 2024, 11:1408760] PubMed: 38860206

人間や獣医の診断であるか治療的な使用のためにでない。