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Glembatumumab vedotin
製品コード：D4054 Batch: D405401
Glembatumumab vedotin (CDX-011 (DOX), CR011,CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.
製品説明
| CAS No. | 1182215-65-1 |
|---|---|
| Formulation | 1xPBS |
| ADC antiody | Glembatumumab |
| ADC cytotoxin | MMAE |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
| Shipping | Shipped under low temperature conditions |
| Purity | 99% |
| Protein concentration | 4.30 mg/ml |
| Endotoxin Level | ＜1EU/mg |
人間や獣医の診断であるか治療的な使用のためにでない。