Heparan Sulfate

製品コードS5992 バッチS599202

化学情報

	Synonyms	HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan	Storage (From the date of receipt)	3 years -20°C powder
	化学式	--
	分子量		CAS No.	9050-30-0
Solubility (25°C)*	体外	Water	100 mg/mL
		DMSO	Insoluble
		Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

生物活性

製品説明	Heparan sulfate (HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan), a constituent of HS proteoglycans (HSPGs), is a linear polysaccharide present on the cell surface. Heparan sulfate influences the binding affinity of intestinal epithelium cells (IECs) to Wnt, thereby promoting activation of canonical Wnt signaling and facilitating regeneration of small intestinal crypts after epithelial injury.

製品説明

Heparan sulfate (HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan), a constituent of HS proteoglycans (HSPGs), is a linear polysaccharide present on the cell surface. Heparan sulfate influences the binding affinity of intestinal epithelium cells (IECs) to Wnt, thereby promoting activation of canonical Wnt signaling and facilitating regeneration of small intestinal crypts after epithelial injury.

プロトコル(参考用のみ)

参考

[1] Shuji Yamamoto, et al. Am J Physiol Gastrointest Liver Physiol. 2013 Aug 1;305(3):G241-9.

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier [ Mol Genet Genomics, 2022, 297(2):397-405]	PubMed: 35103870
Phenotypic spectrum of FGF10-related disorders: a systematic review [ PeerJ, 2022, 10:e14003]	PubMed: 36124135
Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei [ Glycobiology, 2019, 29-8:572-581]	PubMed: 31143933
Contrasting transcriptome landscapes of rabbit pluripotent stem cells in vitro and in vivo [ Anim Reprod Sci, 2014, 149(1-2):67-79]	PubMed: 25059199
Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry [ Glycobiology, 2007, 17(9):972-82]	PubMed: 17623722
KATAMARI1/MURUS3 Is a novel golgi membrane protein that is required for endomembrane organization in Arabidopsis [ Plant Cell, 2005, 17(6):1764-76]	PubMed: 15863516
The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis [ EMBO Rep, 2000, 1(3):282-6]	PubMed: 11256613

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。