Iopromide

製品コードS3207 バッチS320701

印刷

化学情報

Synonyms

N/A

Storage
(From the date of receipt)

3 years -20°C powder
1 years -80°C in solvent

化学式

C₁₈H₂₄I₃N₃O₈

分子量

791.11

CAS No.

73334-07-3

Solubility (25°C)*

体外

DMSO

100 mg/mL (126.4 mM)

Water

100 mg/mL (126.4 mM)

Ethanol

100 mg/mL (126.4 mM)

体内（毎回新しく調製した物を用意してください）

Homogeneous suspension

CMC-NA

≥5mg/ml

Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	Iopromideは、血管内投与用の低浸透圧性非イオン性X線造影剤です。造影剤の流路にある血管を不透過にすることで造影剤として機能し、有意な血液希釈が起こるまで内部構造のX線可視化を可能にします。
in vitro	No toxic effects are detected at the highest tested concentration of Iopromide (10 g/L) in short-term toxicity tests with bacteria (Vibrio fisheri, Pseudomonas putida), algae (Scenedesmus subspicatus), crustaceans (Daphnia magna), and fish (Danio rerio, Leuciscus idus). This compound results in the ratio between the predicted environmental concentration (PEC) and the predicted no-effect concentration (PNEC) of 2 × 10^-4 using an assessment factor of 100. It results in the photocatalytic degradation values k of 0.18 and the coefficient of determination R² of 0.997 in Milli-Q water with suspended TiO₂. The percent removal of this chemical decreases from 97% to 86% when the activity of the nitrifying bacteria is inhibited. This compound results in metabolite of carboxylate formed during the oxidation of the primary alcohol on the side chain of iopromide when the nitrifying bacteria are inhibited. It (0.1 mg/L to 0.27 mg/L) is removed more effectively in the nitrifying activate sludge which has a higher SRT (49 days) than in the conventional activated sludge (SRT of 6 days). This chemical (0.1 mg/L to 0.27 mg/L) is removed more effectively in the nitrifying activate sludge which has a higher SRT (49 days) than in the conventional activated sludge (SRT of 6 days). The percent removal of it in the wastewater treatment plants reaches 61% in nitrifying activated sludge. This compound-dosed plant at 0.1 mg/L, 1 mg/L and 100 mg/L results in the median of DOC-degradation of the synthetic sewage of 88.5%, 90.5%, 88.4% and 85.1%, respectively. It is eliminated to more than 80% in the 100 mg/L concentration after a lag period of 31 days. In the LSTP incubated with 1 mg/L this chemical elimination reaches more than 80% after 38 days. It results in half-life of photodegradation of free amine of 4.21 hours.

製品説明

Iopromideは、血管内投与用の低浸透圧性非イオン性X線造影剤です。造影剤の流路にある血管を不透過にすることで造影剤として機能し、有意な血液希釈が起こるまで内部構造のX線可視化を可能にします。

in vitro

No toxic effects are detected at the highest tested concentration of Iopromide (10 g/L) in short-term toxicity tests with bacteria (Vibrio fisheri, Pseudomonas putida), algae (Scenedesmus subspicatus), crustaceans (Daphnia magna), and fish (Danio rerio, Leuciscus idus). This compound results in the ratio between the predicted environmental concentration (PEC) and the predicted no-effect concentration (PNEC) of 2 × 10^-4 using an assessment factor of 100. It results in the photocatalytic degradation values k of 0.18 and the coefficient of determination R² of 0.997 in Milli-Q water with suspended TiO₂. The percent removal of this chemical decreases from 97% to 86% when the activity of the nitrifying bacteria is inhibited. This compound results in metabolite of carboxylate formed during the oxidation of the primary alcohol on the side chain of iopromide when the nitrifying bacteria are inhibited. It (0.1 mg/L to 0.27 mg/L) is removed more effectively in the nitrifying activate sludge which has a higher SRT (49 days) than in the conventional activated sludge (SRT of 6 days). This chemical (0.1 mg/L to 0.27 mg/L) is removed more effectively in the nitrifying activate sludge which has a higher SRT (49 days) than in the conventional activated sludge (SRT of 6 days). The percent removal of it in the wastewater treatment plants reaches 61% in nitrifying activated sludge. This compound-dosed plant at 0.1 mg/L, 1 mg/L and 100 mg/L results in the median of DOC-degradation of the synthetic sewage of 88.5%, 90.5%, 88.4% and 85.1%, respectively. It is eliminated to more than 80% in the 100 mg/L concentration after a lag period of 31 days. In the LSTP incubated with 1 mg/L this chemical elimination reaches more than 80% after 38 days. It results in half-life of photodegradation of free amine of 4.21 hours.

プロトコル(参考用のみ)

参考

https://pubmed.ncbi.nlm.nih.gov/10090816/
https://pubmed.ncbi.nlm.nih.gov/14769415/
https://pubmed.ncbi.nlm.nih.gov/4014629/

https://pubmed.ncbi.nlm.nih.gov/17180990/
https://pubmed.ncbi.nlm.nih.gov/11766804/

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長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

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