L-Tryptophan

製品コードS3987 バッチS398701

印刷

化学情報

Synonyms

N/A

Storage
(From the date of receipt)

3 years -20°C powder
1 years -80°C in solvent

化学式

C₁₁H₁₂N₂O₂

分子量

204.23

CAS No.

73-22-3

Solubility (25°C)*

体外

DMSO

11 mg/mL (53.86 mM)

体内（毎回新しく調製した物を用意してください）

Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O この製剤はselleckのラボで検証済みです。上記の溶解方法がご要望を満たさない場合、selleckの営業担当までお問い合わせ頂ければ、個別の試験を行います。	0.550mg/ml (2.69mM)	Taking the 1 mL working solution as an example, add 50 μL of 11 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil この製剤はselleckのラボで検証済みです。上記の溶解方法がご要望を満たさない場合、selleckの営業担当までお問い合わせ頂ければ、個別の試験を行います。	0.090mg/ml (0.44mM)	Taking the 1 mL working solution as an example, add 50 μL of 1.8 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.
in vivo	L-Tryptophan suppresses both serum glucose and insulin levels after oral glucose administration and inhibits glucose absorption from the intestine. It increases glucose-associated energy expenditure in rats in vivo. This compound suppresses the rapid rise in blood glucose after a glucose-rich meal and lessens the burden of insulin secretion from β-cells. Oral administration of this chemical is more effective than intraperitoneal injection^[1].

製品説明

L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.

in vivo

L-Tryptophan suppresses both serum glucose and insulin levels after oral glucose administration and inhibits glucose absorption from the intestine. It increases glucose-associated energy expenditure in rats in vivo. This compound suppresses the rapid rise in blood glucose after a glucose-rich meal and lessens the burden of insulin secretion from β-cells. Oral administration of this chemical is more effective than intraperitoneal injection^[1].

プロトコル(参考用のみ)

動物実験	動物モデル	Four-week-old male normal Sprague-Dawley rats
	投薬量	62.5 mg/kg
	投与方法	Oral administration

参考

https://www.jstage.jst.go.jp/article/jnsv/58/6/58_415/_pdf

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation [ Proc Natl Acad Sci U S A, 2022, 119(47):e2208886119]	PubMed: 36375056

Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation [ Proc Natl Acad Sci U S A, 2022, 119(47):e2208886119]

PubMed: 36375056

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。