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受注:045-509-1970 |
技術サポート:tech@selleck.co.jp 平日9:00〜18:00 1営業日以内にご連絡を差し上げます |
製品コード:A2036 Batch: A203602
Magrolimab (anti-CD47) (5F9, GS-4721,Hu5F9 G4,ONO 7913) is a first-in-class macrophage immune checkpoint inhibitor that mainly binds to N-terminal pyroglutamate of CD47.
| CAS No. | 2169232-81-7 |
|---|---|
| Formulation | PBS Buffer, PH 7.4 |
| Isotype | Human IgG4 |
| Application | Magrolimab (anti-CD47) |
| Source | CHO cells |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
| Shipping | Shipped under low temperature conditions |
| Purity | 99% |
| Protein concentration | 6.05mg/ml |
| Endotoxin Level | <1 EU/mg |
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| The "don't eat me" signal CD47 is associated with microglial phagocytosis defects and autism-like behaviors in 16p11.2 deletion mice [ Proc Natl Acad Sci U S A, 2025, 122(16):e2411080122] | PubMed: 40238451 |
| Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy [ Front Immunol, 2025, 16:1518787] | PubMed: 40078999 |
人間や獣医の診断であるか治療的な使用のためにでない。