Mequinol

製品コードS4077 バッチS407701

印刷

化学情報

Synonyms

N/A

Storage
(From the date of receipt)

3 years -20°C powder
1 years -80°C in solvent

化学式

C₇H₈O₂

分子量

124.14

CAS No.

150-76-5

Solubility (25°C)*

体外

DMSO

25 mg/mL (201.38 mM)

Water

25 mg/mL (201.38 mM)

Ethanol

25 mg/mL (201.38 mM)

体内（毎回新しく調製した物を用意してください）

Homogeneous suspension

CMC-NA

≥5mg/ml

Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	Mequinol (4-Methoxyphenol) is a depigmentation agent.
in vitro	Mequinol, diluted in the culture medium or used topically at the top of the RE, leads to a decrease in pigmentation with a diminished melanin transfer human keratinocytes and melanocytes. This compound induces a diminution of dopa-positive melanocyte counts. ^[1] It is available in the United States in 2% concentration and is commercially marketed as a prescription skin lightener in combination with 0.01% tretinoin, functioning as a penetration enhancer, and vitamin C, in the form of ascorbic acid and ascorbyl palmitate, to enhance skin lightening. This chemical is a substrate for tyrosinase thereby acting as a competitive inhibitor in the formation of melanin precursors. ^[2]

製品説明

Mequinol (4-Methoxyphenol) is a depigmentation agent.

in vitro

Mequinol, diluted in the culture medium or used topically at the top of the RE, leads to a decrease in pigmentation with a diminished melanin transfer human keratinocytes and melanocytes. This compound induces a diminution of dopa-positive melanocyte counts. ^[1] It is available in the United States in 2% concentration and is commercially marketed as a prescription skin lightener in combination with 0.01% tretinoin, functioning as a penetration enhancer, and vitamin C, in the form of ascorbic acid and ascorbyl palmitate, to enhance skin lightening. This chemical is a substrate for tyrosinase thereby acting as a competitive inhibitor in the formation of melanin precursors. ^[2]

プロトコル(参考用のみ)

参考

https://pubmed.ncbi.nlm.nih.gov/9080893/
https://pubmed.ncbi.nlm.nih.gov/18045355/

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。