Spartalizumab (anti-PD-1)

製品コード：A2017         Batch: A201701

印刷

Spartalizumab is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1. It binds to PD-1 with high affinity and inhibits the biological activity of PD-1, MW: 145.8 KD.

製品説明

CAS No. 1935694-88-4
Formulation PBS buffer, pH 7.2
Isotype Human IgG4
Source CHO cells
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Purity 99.0%
Protein concentration 5.0 mg/ml
Endotoxin Level ≤1 EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Vinburnine potentiates anti-PD1 immunotherapy in melanoma through IL-24 secretion via P38/MAPK/ATF3 signaling [ J Exp Clin Cancer Res, 2025, 44(1):255] PubMed: 40866941
Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α. [ Elife, 2020, 9] PubMed: 32091388

人間や獣医の診断であるか治療的な使用のためにでない。