Sulfaguanidine

製品コードS4175 バッチS417501

印刷

化学情報

Chemical Structure Synonyms N/A Storage
(From the date of receipt)		 3 years -20°C powder
1 years -80°C in solvent
化学式

C7 H10N4O2S
分子量 214.24 CAS No. 57-67-0
Solubility (25°C)* 体外 DMSO 43 mg/mL (200.7 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明 Sulfaguanidine is a sulfonamide used as an anti-infective agent.
in vitro Sulfaguanidine is the first sulfonamide designed to treat enteric infections. Sulfaguanidine have been found to be particularly effective in preventing the growth of the gram-negative intestinal bacilli. It is a useful tool for the inhibition of synthesis of nutritional factors by intestinal bacteria. [1]
in vivo In adult rats, sulfaguanidine's elimination from plasma, after intravenous administration of 2.5 or 25 mg/kg doses, while its plasma concentration after oral administration of 25 mg/kg doses. Neonatal rats displayed a lower elimination of sulfaguanidine than adult rats. Comparison of the drug's gastrointestinal absorption shows that the maximum plasma concentration after oral administration is significantly higher for neonatal than for adult rats. However, there is no significant difference between the times required to reach maximum plasma concentrations. The absolute bioavailability (57.86%) in neonatal rats is approximately five times that (12.76%) in adult rats. Thus, sulfaguanidine is poorly absorbed by adult rats, but is efficiently absorbed by immature gastrointestines of neonatal rats. [1]

プロトコル(参考用のみ)

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。