Trastuzumab (anti-HER2)

製品コード:A2007         Batch: A200709

印刷

Trastuzumab is a humanized, recombinant monoclonal antibody that binds to the extracellular domain of HER2, MW:145.53 KD.

製品説明

CAS No. 180288-69-1
Formulation 1×PBS, pH6.0
Isotype Human IgG1
Source CHO cells
Storage
(From the date of receipt)
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Purity 99%
Protein concentration 7.49 mg/ml
Endotoxin Level <1EU/mg

カスタマーフィードバック

A2007-Trastuzumab-(anti-HER2).gif

Selleckの高級品が、幾つかの出版された研究調査結果(以下を含む)で使われた:

CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells [ Cell Rep Med, 2025, 6(1):101889] PubMed: 39793572
Engineering unnatural amino acids in peptide linkers enables cathepsin-selective antibody-drug conjugates for HER2-positive breast cancer [ J Control Release, 2025, 387:114269] PubMed: 41015259
Characterization of ex vivo expanded natural killer cells for cancer immunotherapy [ Immunol Cell Biol, 2025, 10.1111/imcb.70038] PubMed: 40533418
Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy [ Cell Death Dis, 2024, 15(7):480] PubMed: 38965233
Identification of a novel potent CDK inhibitor degrading cyclinK with a superb activity to reverse trastuzumab-resistance in HER2-positive breast cancer in vivo [ Eur J Med Chem, 2024, 264:116014] PubMed: 38061230
Additional statin treatment enhances the efficacy of HER2 blockade and improves prognosis in Rac1-high/HER2-positive breast cancer [ Biochim Biophys Acta Mol Basis Dis, 2024, 1870(8):167458] PubMed: 39128642
Induction of SUSD2 by STAT3 Activation Is Associated with Tumor Recurrence in HER2-Positive Breast Cancer [ Cells, 2024, 14(1)19] PubMed: 39791720
Trastuzumab Potentiates Antitumor Activity of Thiopyrano[2,3-d]Thiazole Derivative in AGS Gastric Cancer Cells [ Molecules, 2024, 29(21)5117] PubMed: 39519758
Investigation of ITGB3 Heterogeneity to Overcome Trastuzumab Resistance in HER2-Positive Breast Cancer [ Biology (Basel), 2024, 14(1)9] PubMed: 39857240
Inorganic sulfides prevent osimertinib-induced mitochondrial dysfunction in human iPS cell-derived cardiomyocytes [ J Pharmacol Sci, 2024, 156(2):69-76] PubMed: 39179336

人間や獣医の診断であるか治療的な使用のためにでない。