Trastuzumab deruxtecan (DS-8201a, T-DXd)

製品コード：D4001         Batch: D400110

印刷

Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa.

製品説明

CAS No. 1826843-81-5
Formulation 100 mM Pro-Ac, 20 mM Arg, pH 5.0
DAR 7.8
ADC antiody Trastuzumab
ADC cytotoxin DXd
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Shipping Shipped under low temperature conditions
Purity 98.27%
Protein concentration 20 mg/mL
Endotoxin Level ＜1 EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Identification of asporin as a HER3 ligand exposes a therapeutic vulnerability in prostate cancer [ JCI Insight, 2025, 10(16)e187151] PubMed: 40857406

人間や獣医の診断であるか治療的な使用のためにでない。