Uracil

製品コードS4177 バッチS417701

印刷

化学情報

Synonyms

N/A

Storage
(From the date of receipt)

3 years -20°C powder
1 years -80°C in solvent

化学式

C₄H₄N₂O₂

分子量

112.09

CAS No.

66-22-8

Solubility (25°C)*

体外

DMSO

22 mg/mL (196.27 mM)

Water

Insoluble

Ethanol

Insoluble

体内（毎回新しく調製した物を用意してください）

Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 Corn oil この製剤はselleckのラボで検証済みです。上記の溶解方法がご要望を満たさない場合、selleckの営業担当までお問い合わせ頂ければ、個別の試験を行います。	2.000mg/ml (17.84mM)	Taking the 1 mL working solution as an example, add 50 μL of 40 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical.
in vitro	Uracil can be used for drug delivery and as a pharmaceutical. It can be reacted with elemental fluorine to produce 5-fluorouracil, which can inhibit RNA replication enzymes, eliminate RNA synthesis and stop the growth of cancerous cells. This compound can also be used in the synthesis of caffeine. Its use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. It serves as allosteric regulator and coenzyme for reactions in the human body and in plants. UMP controls the activity of carbamoyl phosphate synthetase and aspartate transcarbamoylase in plants, while UDP and UTP requlate CPSase II activity in animals. UDP-glucose regulates the conversion of glucose to galactose in the liver and other tissues in the process of carbohydrate metabolism. This chemical is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes.

製品説明

Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical.

in vitro

Uracil can be used for drug delivery and as a pharmaceutical. It can be reacted with elemental fluorine to produce 5-fluorouracil, which can inhibit RNA replication enzymes, eliminate RNA synthesis and stop the growth of cancerous cells. This compound can also be used in the synthesis of caffeine. Its use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. It serves as allosteric regulator and coenzyme for reactions in the human body and in plants. UMP controls the activity of carbamoyl phosphate synthetase and aspartate transcarbamoylase in plants, while UDP and UTP requlate CPSase II activity in animals. UDP-glucose regulates the conversion of glucose to galactose in the liver and other tissues in the process of carbohydrate metabolism. This chemical is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes.

プロトコル(参考用のみ)

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics [ Lab Chip, 2024, 24(23):5251-5263]	PubMed: 39485368
Patient-derived rhabdomyosarcoma cells recapitulate the genetic and transcriptomic landscapes of primary tumors [ iScience, 2024, 27(10):110862]	PubMed: 39319271

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。