Vibostolimab (anti-TIGIT)

製品コード：A2033 Batch: A203305

Vibostolimab (anti-TIGIT, MK-7684) is a humanized monoclonal antibody that binds to the T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT), blocking the interaction between TIGIT and its ligands, CD112 and CD155, thereby activating T lymphocytes which help to destroy tumor cells.

製品説明

CAS No.	2231305-30-7
Formulation	100 mM Pro-Ac, 20 mM Arg, pH5.0
Isotype	Human IgG1, κ
Source	CHO cells
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions
Purity	99%
Protein concentration	4.91mg/ml
Endotoxin Level	＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer [ Nat Cancer, 2025, 10.1038/s43018-025-00948-9]	PubMed: 40240620

Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer [ Nat Cancer, 2025, 10.1038/s43018-025-00948-9]

PubMed: 40240620

人間や獣医の診断であるか治療的な使用のためにでない。