Bremelanotide Acetate

製品コード：P1108 純度：99.97%

Bremelanotide Acetate (PT-141 Acetate) is a melanocortin receptor (MCR) agonist recently approved in the USA for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD), as characterized by low sexual desire that causes marked distress or interpersonal difficulty.

Amino-acid Sequence

CAS No. 1607799-13-2

サイズ	価格(税別)	在庫状況
5mg	JPY 14900	国内在庫あり
25mg	JPY 40800	国内在庫あり
バルクサイズ	バルク特価あり

代表番号: 045-509-1970\|電子メール：[email protected] よく尋ねられる質問

製品安全説明書

現在のバッチを見る： P110801 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] 100 mg/mL] false 純度： 99.97%

99.97

化学情報

保管	3 years-20°C powder	溶液の保管冷凍と解凍の繰り返しを避けるため小分けにしてください	1年-80°Cin solvent
			1个月-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (92.14 mM)；吸湿したDMSOは溶解度を減少させます。新しいDMSOをご使用ください。)

Water : 100 mg/mL

Ethanol : 100 mg/mL

モル濃度計算器

in vivo
Batch:

Add solvents to the product individually and in order.

投与溶液組成計算機

生物活性

製品説明	Bremelanotide Acetate (PT-141 Acetate) is a melanocortin receptor (MCR) agonist recently approved in the USA for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD), as characterized by low sexual desire that causes marked distress or interpersonal difficulty.

In Vivo
In vivo	Bremelanotide, an analogue of the naturally occurring peptide a-MSH, activates the medial preoptic area (mPOA) and other hypothalamic and limbic regions of the brain involved in sexual behavior, and may work by activating dopamine terminals in the mPOA.^[2]
動物実験	動物モデル	rat model of sexual desire
	投与量	5, 100, 200, 800 μg/kg
	投与経路	s.c.

参考
[1] Dhillon S, et al. Drugs. 2019 Sep;79(14):1599-1606. [2] Pfaus J, et al. J Sex Med. 2007 Nov;4 Suppl 4:269-79.

参考

製品情報

Molecular Formula	C₅₀H₆₈N₁₄O₁₀.C₂H₄O₂
Molecular Weight	1085.22
CAS No.	1607799-13-2
Appearance	White Powder
Peptide Content (by %N)	≥80%
Single Impurity (by HPLC)	≤1.0%
Assay (By Anhydrous, Acetic Acid-free)	95.0~105.0%
MS	Consistent
Packing	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt)	3 years-20°C powder
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)