天然製品ライブラリー

目录号 L1400

173種類天然製品の集め

サイズ 価格(税別)  
予めDMSOに溶解します
100uL/well (10mM solution) JPY 296476.00
2x100uL/well (10mM solution) JPY 484056.00
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お客様自分の特別なニーズに満たすために、お客様は弊社の製品を数量、状態(乾燥状態/固体/DMSO等)等で選択できます。

天然製品ライブラリー内容

お客様叙述(9)

  • Cells expressing wild type EGFR (HCC827 and H1650) or L858R/T790M mutant EGFR (HCC827GR) were treated with different concentration of ILQ for 24 h, and the expression of apoptotic markers was detected by immunoblotting.

    J Biol Chem 2014 289(52), 35839-48. Isoliquiritigenin purchased from Selleck

    PLoS One 2013 8(8), e69519. (-)-Epigallocatechin Gallate purchased from Selleck

  • PLoS One 2013 8(8), e69519. (-)-Epigallocatechin Gallate purchased from Selleck

    16h after seeding HMLE RAS cells were exposed to 5 uM or 10 uM Gossypol in the presence or absence of Cisplatin for 16h. Afterwards, cells were harvested and lysates were analyzed for apoptosis by western blotting. Actin staining was used as loading control, while LC3a/b staining was used as indicator for autophagy. Accumulation of LC3a/b II indicates autophagy. Non-treated and DMSO-treated cells were used as control. Arrows are indicating the intended staining. For Bcl-xL: * indicates deamidated protein, # indicates unmodified protein. n=1.

    Georg August University Gottingen 2014 Western blotting. gossypol-Acetic acid purchased from Selleck

  • Repression of BSEP gene expression upon treatment with reported BSEP inhibitors in human primary hepatocytes. BSEP mRNA expression was measured using real-time PCR in hepatocytes from at least three donors upon treatment with BSEP inhibitors as described under Materials and Methods. All the data are expressed as mean ?S.D. (n = 3).

    Biochim Biophys Acta 2013 1833(3), 652-62. Cyclosporin A purchased from Selleck

    Immunophilins participate in SOCE activation by CN-dependent but also CN-independent signaling pathways. Fura-2 loaded platelets were suspended in HBS, platelets are incubated for 5 min with cyclosporin A (CsA, 50 µM). Once incubation time was over, platelets were stimulated with TG (200 nM) in a calcium free-HBS (EGTA 100 μM was added as indicated the by arrowhead) and 4 min later CaCl2 (300 µM) was added to visualized calcium entry. Changes in fura-2 fluorescence were monitored using the 340/380nm ratio and calibrated in terms of [Ca2+]c . Traces are representative of four to six independent experiments. *,**, *** represents p < 0.05, p < 0.01 and p <0.001, respect control platelets.

    Biochim Biophys Acta 2013 1833(3), 652-62. Cyclosporin A purchased from Selleck

  • Tuberc Respir Dis 2013 75(1), 9-17. Sodium Monensin purchased from Selleck

    After starved in serum-free medium for 24h,A549 cells incubated with the indicated concentrations of Quercetin for 3h,followed by 20-minute stimolation of 100ng/ml EGF.

    2011 Quercetin purchased from Selleck

  • After starved in serum-free medium for 24h, A549 cells incubated with the indicated concentrations of Chrysophanic acid for 3h,followed by 15-minute stimolation of 100ng/ml EGF

    2011 Chrysophanic Acid purchased from Selleck

製品特性&メリット

• 173種類天然製品の集めはHTSとHCS (high content screening) に使用します。
• 構造多様で、効果が目立って、細胞浸透可。
• 十分に詳しい構造説明、,IC50値とお客様からフィードバックした資料があります。
• NMRとHPLC技術で製品の高純度を保証します。

製品詳細情報

調合: 173種類天然製品は予めDMSO溶液に溶解します。
96穴板: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
安定性: in DMSO
in DMSO
出荷方式: ブルーアイス物流
包装: 不活性ガス(Inert gas)

天然製品ライブラリー製品説明

HTS パートナ

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