カゼインキナーゼ
- 阻害剤の選択性比較
- 溶解度
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S2248 | Silmitasertib (CX-4945) | <1 mg/mL | 16 mg/mL | <1 mg/mL |
| S7642 | D 4476 | <1 mg/mL | 79 mg/mL | <1 mg/mL |
| S8237 | IC261 | <1 mg/mL | 62 mg/mL | <1 mg/mL |
亜型選択性的な製品
- Casein Kinase阻害剤(3)
| 製品コード | 製品説明 | 文献中の使用例 | お客様のフィードバック |
|---|---|---|---|
| S2248 |
Silmitasertib (CX-4945)Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Phase 1/2. |
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| S7642 |
D 4476D 4476 is a potent, selective, and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1δ, respectively. Also acts as an ALK5 inhibitor with IC50 of 500 nM. |
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| S8237 |
IC261IC261 is a novel inhibitor of CK1. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM. |
