Nrf2

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1848 Curcumin <1 mg/mL 73 mg/mL <1 mg/mL
S7864 Oltipraz <1 mg/mL 39 mg/mL <1 mg/mL
S3784 Obacunone -1 mg/mL 90 mg/mL -1 mg/mL
製品コード 製品説明 文献中の使用例 お客様のフィードバック
S1848

Curcumin

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase(IC50~25 μM) and Histone deacetylase; activates Nrf2 pathway and supresses the activation of transcription factor NF-κB.

S7864

Oltipraz

Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3.

S3784

Obacunone

S4712

Diethylmaleate

Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.