Doxorubicin (Adriamycin) HCl

Licensed by Pfizer 製品コードS1208 別名:NSC 123127

Doxorubicin (Adriamycin) HCl化学構造

分子量(MW):579.98

Doxorubicin (Adriamycin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis in tumor cells.

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JPY 19422.00
JPY 14940.00
JPY 34860.00
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文献中の使用例(33)

カスタマーフィードバック(9)

  • Enhancement of apoptotic response by addition of targeted agents lapatinib and sunitinib to doxorubicin in the same device reservoir at 24 hours. P values were determined using Student’s t test for all graphs.

    Sci Transl Med, 2015, 7(284): 284ra57 . Doxorubicin (Adriamycin) HCl purchased from Selleck.

    (F) Kaplan-Meier curves are shown for all groups described: no hydrogel, a hydrogel loaded with paclitaxel, or a hydrogel loaded with doxorubicin. The number of mice per group (n) and median survival (ms) are listed. The experiment was performed at least three times.

    Science, 2018, 10(433), doi: 10.1126/scitranslmed.aar1916. Doxorubicin (Adriamycin) HCl purchased from Selleck.

  • Cell viabilities with increasing concentrations of cisplatin (CP) and doxorubicin (DOXO) under normoxic and hypoxic condition for 48 hours were determined by MTT assay. IC50 values are presented as the means ?SDs (n=4) and * denotes p<0.05.

    Cancer Res 2014 74, 298-308. Doxorubicin (Adriamycin) HCl purchased from Selleck.

    Cleavage of caspase-3, -9 and the expression of PARP were measured by western blot using b-actin as a loading control.

    Cell Cycle, 2017, 16(5):468-476. Doxorubicin (Adriamycin) HCl purchased from Selleck.

  • (C) & (D) Treatments with doxorubicin, cisplatin or AZD6244 further decreased the cell viability in RH30 cloned cells in which STAT3 or GP130 was knockdown by shRNA. (*P<.05, ** P <.01, *** P <.001).

    Curr Cancer Drug Targets, 2016, 16(7):631-8. Doxorubicin (Adriamycin) HCl purchased from Selleck.

     

    Doxorubicin release of P(MAA-g-EG) and P(MAA-g-EG) containing nanoparticles in two-step pH conditions. Doxorubicinloaded P(MAA-g-EG) ,P(MAA-g-EG)-1.0NP ,P(MAA-g-EG)-2.5NP, and P(MAA-g-EG)-5.0NP crushed particles (75–150 um) were released in 1 PBS (pH 2.0) for 90 min. Then the pH was increased to 7.0 by adding 5N NaOH and release continued for 6 h.

    J Biomed Mater Res Part A 2012 10.1002/jbm.a.34064. Doxorubicin (Adriamycin) HCl purchased from Selleck.

  • Temporal uptake of free DOX or DOX-PCL63-b-PNVP90 micelles into K-562 (I) and DL (J) cells were studied by incubating in 24-well plates at a concentration of 50,000 cells per well. Representative images shown were obtained using a fluorescence microscope Eclipse 80i (Nikon, Japan) (Plan Fluor, 40X, NA 0.75 objective) equipped with blue and red filters for, Hoechst and Doxorubicin respectively (n = 3).

    PLoS One 2014 9, e94309. Doxorubicin (Adriamycin) HCl purchased from Selleck.

    PLoS One 2013 8(1), e54595. Doxorubicin (Adriamycin) HCl purchased from Selleck.

  • CON+ -positive control (with FBS as chemoattractant); CON- - negative control (without chemoattractant); DOX -doxorubicin; WZ -WZ811; PF- PF-573228; * -significant difference compared to positive control: p<0.05; ** -significant difference compared to positive control: p<0.01; # -significant difference between combination and inhibitor only: p<0.05. Cancer cell invasion was analyzed using Transwell membranes assembled in 24-well plates and covered with a layer of Matrigel. COR-L23 cells were treated for 24 h with 50 nM DOX, 10 uM WZ811, 5 uM PF-573228 and combinations of inhibitors with 50 nM DOX. Similarly, RH460 cells were treated for 24 h with 1 uM DOX, 10 uM WZ811, 2.5 uM PF-573228 and combinations of inhibitors with 1 uM DOX. Applied doses were the ones that exerted the most pronounced synergistic effect on cytotoxicity level. After the incubation period, cells that invaded through matrigel and membranes were fixed in 4% paraformaldehyde-PBS and stained with Hoechst 33342 nuclear stain. Cells were visualized and counted under a fluorescent microscope at 10x magnification.

    2014 Dr Milica Pesic from Institute for Biological Research. Doxorubicin (Adriamycin) HCl purchased from Selleck.

製品安全説明書

Topoisomerase阻害剤の選択性比較

生物活性

製品説明 Doxorubicin (Adriamycin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis in tumor cells.
ターゲット
Topo II [1]
(Tumor cells)
体外試験

Doxorubicin, an antibiotic anthracycline, is commonly considered to exert its anti-tumor activity at two fundamental levels, altering DNA and producing free radicals to trigger apoptosis of cancer cells through DNA damage. Doxorubicin can block the synthesis of DNA by intercalating into the DNA strand, and inhibits DNA topoisomerase II (TOP2). Doxorubicin is most effective when cells are rapidly proliferating and expressing high levels of TOP2. Additionally, Doxorubicin can trigger apoptosis by producing ceramide (which prompts apoptosis by activating p53 or other downstream pathways such as JNK), the degradation of Akt by serine threonine proteases, the mitochondrial release of cytochrome c, increased FasL (death receptor Fas/CD95 ligand) mRNA production, and a greater production of free radicals. [2] Pre-treatment with GSNO (nitrosoglutathione) suppresses the resistance in the doxorubicin-resistant breast cancer cell line MCF7/Dx, accompanied by enhanced protein glutathionylation and accumulation of doxorubicin in the nucleus. [3] Doxorubicin induced G2/M checkpoint arrest are attributed to elevated cyclin G2 (CycG2) expression and phospho-modification of proteins in the ataxia telangiectasia mutated (ATM) and ATM and Rad3-related (ATR) signaling pathways. [5] Doxorubicin inhibits AMP-activated protein kinase (AMPK), resulting in SIRT1 dysfunction, p53 accumulation, and increased cell death in mouse embryonic fibroblasts (MEFs) and cardiomyocytes, which can be further sensitized by pre-inhibition of AMPK. [6] Doxorubicin elicits a marked heat shock response, and that either inhibition or silencing of heat shock proteins enhance the Doxorubicin apoptotic effect in neuroblastoma cells. Nanomolar Doxorubicin treatment of neuroblastoma cells causes dose-dependent over-ubiquitination of a specific set of proteins in the absence of measurable inhibition of proteasome, and loss of activity of ubiquitinated enzymes such as lactate dehydrogenase and α-enolase, the protein ubiquination patterns of which is similar to those with proteasome inhibitor Bortezomib, indicating that Doxorubicin may also exert its effect by damaging proteins. [8]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
L1210 MYLGeY5kfGmxbjDBd5NigQ>? MVrJcohq[mm2aX;uJI9nKFKQQTDzfY51cGW|aYOge4l1cCCHREWwJI9nKDBwNUig{txO M2HMVFQ6ODV|Nh?=
Yoshida sarcoma MY\GeY5kfGmxbjDBd5NigQ>? NGTRdVBKdmirYnn0bY9vKG:oIGuzTH1V\FJiaX7jc5Jxd3KjdHnvckB4cXSqIFnDOVAhd2ZiMD6wNkDPxE1? NXvoSYtKOTN{Mkm4Oi=>
CHO MoPlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnPjTWM2OD1yLkC2JO69VQ>? MWKxN|U1PzVy
8226 MlfQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWjJR|UxRTBwMEOzJO69VQ>? MnW5NVQ1Pzd|MB?=
8226/ADR NXew[ZE3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFHmc3VKSzVyPUCuOVYh|ryP NIXhcGsyPDR5N{Ow
MCF7/ADR MnizS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;5c|RKSzVyPUOuNUDPxE1? MX[xOFQ4PzNy
H69 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HWZmlEPTB;MD64O{DPxE1? MlO1NVQ4QTV6NR?=
N417 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEThclVKSzVyPUCuNlMh|ryP Mm[2NVQ4QTV6NR?=
H9 M1q5b2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDOTY5pcWKrdHnvckBw\iCKOTDj[YxteyClaILvcolk[WyueTDpcoZm[3SnZDD3bZRpKHSqZTDITXYuOSBqSEmvTWlKSilid3n0bEBKTDVyIH;mJFAvODFizszN M2fybFE2PDh4OEG=
T-C8166 MnXZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\LdZJ7UUR3ME2wMlAyKM7:TR?= NY\rRpBTOTV2OE[4NS=>
T-H9 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfUTWQ2OD1yLkCxJO69VQ>? NF\F[YcyPTR6Nkix
T-MT4 NWS4eoZ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7RbGlKTDVyPUCuNFEh|ryP MYWxOVQ5Pjhz
SKMEL-5 Mm[wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYf2eZluTUR3ME2zMlIh|ryP NXT0eI9tOTZzM{e1Ny=>
MLM NXrCPJZKS3m2b4TvfIlkKEG|c3H5 MmHhSWQ2OD1yLkGzJO69VQ>? NV;H[GtnOTh5NUO1NC=>
KBM-3 M2LPXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{myUGlEPTB;MD6wNlYh|ryP NEHOVXMyQTl3OEe3
HT-29 MmfXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVqwMlAyKM7:Zx?= NXHUb|dJPDhiaB?= M2\UZ2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5 NY\yUndsOjd5OES0PS=>
EMT6 MnTmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2PlZVAvPSEQvF2= NHviN5QyKGh? NWfTZWlZUW6qaXLpeIlwdiCxZjDwdo9tcW[ncnH0bY9vKGK7IH3lZZN2emmwZzDmc5Ihe3W{dnn2bY5oKG[{YXP0bY9veyC5aYToJGVFPTBib3[gNE4xODBzIN88US=> M2LZZ|c1PTJ4N{S=
H2981 MX7DfZRwfG:6aXOgRZN{[Xl? NHjrVnNKSzVyPUCuOUDPxE1? NETVb4o4PzNzMEKz
LOX M1zPTGN6fG:2b4jpZ{BCe3OjeR?= MXzJR|UxRTBwMESyJO69VQ>? NWHLW4hXPzh3M{OzNS=>
C38 MkTGR5l1d3SxeHnjJGF{e2G7 NHH2VldKSzVyPUCuNFEh|ryP NX71UFE3QDB3N{K5NS=>
EAC MoDsR5l1d3SxeHnjJGF{e2G7 NWPDV45FPzJiaB?= MUPJR|UxRTBwM{Wg{txO NUfyTItpQDN3MEC4Oy=>
SKVLB MX7DfZRwfG:6aXOgRZN{[Xl? NHO0[ZpKSzVyPUWuOkDPxE1? NEmwe485PTd4OUG0
AUC375 MlnPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTGTWM2OD1yLkGxNkDPxE1? NU\VSGJvQDZ2OE[wNC=>
A2780-C25 NYXkXnVMS3m2b4TvfIlkKEG|c3H5 M1zwc2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KG:6YXzpdIxifGmwLYLld4l{fGGwdDDBNlc5OC2FMkWge4l1cCCLQ{WwJI9nKDBwME[zJO69VQ>? NGPBbWM5QDNzN{W1
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A2780-DX5 NWq1SlM2S3m2b4TvfIlkKEG|c3H5 M{faU2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGSxeH;yeYJq[2mwLYLld4l{fGGwdDDBNlc5OC2GWEWge4l1cCCLQ{WwJI9nKDBwM{W3JO69VQ>? NVriUZBrQDh|MUe1OS=>
MXF7 M1HUc2N6fG:2b4jpZ{BCe3OjeR?= M2nI[2FvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JJNmdnOrdHn2[UBOYEZ5IIfpeIghUUN3MDDv[kAxNjB{ODFOwG0> Mn;0PFk3ODV3OB?=
MXF7 MV7DfZRwfG:6aXOgRZN{[Xl? NV3jbWRiSW62aYT1cY9zKGGldHn2bZR6KGGpYXnud5QhdWm2b4jhcpRzd26nLYLld4l{fGGwdDDNXGY4KHerdHigTWM2OCCxZjCwMlAzQCEQvF2= M1ruUFg6PjB3NUi=
MXF7 M3fR[GN6fG:2b4jpZ{BCe3OjeR?= MUTBcpRqfHWvb4KgZYN1cX[rdImgZYdicW6|dDDkc5hwenWkaXPpck1z\XOrc4ThcpQhVViINzD3bZRpKEmFNUCgc4YhOS5zN{Kg{txO M{PjVVg6PjB3NUi=
WiDr NY\R[YlHS3m2b4TvfIlkKEG|c3H5 MYjBZ5Rqfmm2eTDh[4FqdnO2IIPlcpNqfGm4ZTDXbWRzKGOnbHyge4l1cCCLQ{WwJI9nKDBwMEWzJO69VQ>? NUXldpRlQDl4MEW1PC=>
MCF NVqyPHR{TnWwY4Tpc44hSXO|YYm= Mlu1VoV3\XK|YXygc4YhWC2pcD3t[YRq[XSnZDDteYx1cWS{dXegdoV{cXO2YX7j[UBie3Onc4Pl[EBieyCnbnjhcoNmdWWwdDDpckBkgXSxdH;4bYNqfHlib3[gZYRzcWGveXPpci=> M2PTPVg6QDRzNUG=
C6 NF;4d5hEgXSxdH;4bYMhSXO|YYm= MkDlNk42KG2pL33M M2X4V|czKGh? NYHpW4ZnTE2VTx?= MmO2R5l1d3SxeHnjbZR6KGGpYXnud5QhemG2IFO2JINmdGy|IHH0JFUxKHWpL33MJJRwKDJwNTDt[{9uVA>? NYTPbZBxQDl6OE[wOC=>
C6 NHjQUFdHfW6ldHnvckBCe3OjeR?= MV[yMlUhdWdxbVy= NVzSOVVZPCCq MofsSG1UVw>? M4jSNWlvcGmkaYTpc44hd2ZidIXieYxqdiCyb3z5cYVzcXqjdHnvci=> MXS4PVg5PjB2
C6 MVHDfZRwfG:6aXOgRZN{[Xl? NHPTOZUzNjVibXevcWw> NG\aeJA2KGh? NWO0RlFXTE2VTx?= M2fMeWN6fG:2b4jpZ4l1gSCjc4Pld5Nm\CCjczDj[YxtKHKnbHXhd4U> MWS4PVg5PjB2
SKVLB MmXYR5l1d3SxeHnjJGF{e2G7 MYS3NkBp M1nUTWlEPTB;Nj61OEDPxE1? NXfP[Vc5QTByM{WyNC=>
MCF7/VP16 MojlR5l1d3SxeHnjJGF{e2G7 Mn[4OVAh|rypL33M M2HGdVczKGh? MUTJR|UxRTF2LkKg{txO M4fTZlkxOjJ5OUK=
CA755 MlrBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFLZ[ZQyOCEQvF2= NVPqdIR5PiCm NV3V[XFzUUN3ME2wMlAyPCEQvF2= M1[2XFk2OjZ3N{C=
CHO NYT5d49DT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NELYelkyOCEQvF2= MkfsOkBl NHm2UXNKSzVyPUCuNFYh|ryP NYTvS3ZiQTV{NkW3NC=>
Panc02 M4nTXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7qOm4yOCEQvF2= MUO2JIQ> MVvJR|UxRTBwME[1JO69VQ>? NXvlSItxQTV{NkW3NC=>
PC14 MWrDfZRwfG:6aXOgRZN{[Xl? NYrWdWMyPCCm MVrEUXNQ MnKxTWM2OD1yLkK5JO69VQ>? MVy5PFIzPTR{
HOP62 NIL3d4VEgXSxdH;4bYMhSXO|YYm= NXrjV3VtPzJiaB?= NIrzOlRKSzVyPUCuNFA1KM7:TR?= MlH3PVg4OzZ4MR?=
SF-295 M3G1bWN6fG:2b4jpZ{BCe3OjeR?= NVzwV5MyPzJiaB?= NXXafWVYUUN3ME2wMlA{PSEQvF2= NV25Vmh1QTh5M{[2NS=>
MDA-MB-361 M1fSSmN6fG:2b4jpZ{BCe3OjeR?= M1f5blEhcA>? MkXGSG1UVw>? Ml7lR5l1d3SxeHnjbZR6KGGpYXnud5QhVUSDLV3CMVM3OSCneIDy[ZN{cW6pIFzhZ3ohf2m2aDDJR|UxKG:oIECuNFEzKM7:TR?= Mn7GNVA{QTV2OUC=
MDA-MB-361 NVj5SYJNS3m2b4TvfIlkKEG|c3H5 NHPzbVcyKGh? MnXkSG1UVw>? MWTDfZRwfG:6aXPpeJkh[WejaX7zeEBOTEFiTVKgN|YyKGW6cILld5NqdmdiY3HyZo95gXCncITp[IF{\SC|dFPQS|Ihf2m2aDDJR|UxKG:oIECuNFE5KM7:TR?= MnfRNVA{QTV2OUC=
CCRF-SB M2TjWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYS0JIQ> MlewSG1UVw>? MYDJR|UxRTBwMEGg{txO NVrneGk4OTB2MUG0O|Y>
CHO-K1 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWq0JIQ> MVLEUXNQ NEHk[nRKSzVyPUCuOEDPxE1? M33UdlExPDFzNEe2
KB NYj0ZXU5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NICwb3g1KGR? MWTEUXNQ NVS5ZZZUSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBlenWpLYLld4l{fGGwdDDLRldFKHerdHigTWM2OCCxZjCwMlY2KM7:TR?= NGTWVVUyODRzMUS3Oi=>
KB MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTrOEBl M3PCXmROW09? NYH2d|JQSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBlenWpLYLld4l{fGGwdDDLRmNidXC5aYToJGlEPTBib3[gNE4xPiEQvF2= M3LmWVExPDFzNEe2
KB MkCzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NILEblQ1KGR? MYnEUXNQ M1PYc2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4Sg[JJ2\y2{ZYPpd5RidnRiS1LNSHIhf2m2aDDJR|UxKG:oIECuOUDPxE1? NW\OPZp[OTB2MUG0O|Y>
KB M2\vbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYG2WngzPCCm M4HTWmROW09? M{LCUmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4Sg[JJ2\y2{ZYPpd5RidnRiS1LWNlBEKHerdHigTWM2OCCxZjCwMlQh|ryP M33IR|ExPDFzNEe2
HTB-54 MkLNR5l1d3SxeHnjJGF{e2G7 NV2xcWp6OTByIN88US=> M1PQfmlEPTB;MT6xJO69VQ>? M1S5OFExPDd4OE[x
MEL-AC MWnDfZRwfG:6aXOgRZN{[Xl? MmWwNVAxKM7:TR?= NVG5W4lzUUN3ME2xMlIh|ryP NWTKTlBvOTB2N{[4OlE>
DU145 MW\DfZRwfG:6aXOgRZN{[Xl? MmHWO|IhcA>? MVjJR|UxRTBwMEWyPEDPxE1? M364SlExPDd7Mkiy
K562R M{DnRmN6fG:2b4jpZ{BCe3OjeR?= NIPnb|c4OiCq M3jYemlEPTB;MD6wNVU3KM7:TR?= MWSxNFQ4QTJ6Mh?=
PACA-2 M3TYfGN6fG:2b4jpZ{BCe3OjeR?= MkXwOkBl NYe3N21MTUR3ME2wMlAxPjNizszN M{nHO|ExPDl6MkG0
3Y1 MoL4R5l1d3SxeHnjJGF{e2G7 M3rkdVczKGh? NEO1WFBIUTVyPUCuNFA{QCEQvF2= NWDROZg6OTB4OUG3NVA>
P388 MXjDfZRwfG:6aXOgRZN{[Xl? MnjwO|IhcA>? MWnHTVUxRTBwMEGyJO69VQ>? M3XJflExPjlzN{Gw
HMV-1 NH[zXVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzreXFRUUN3ME2wMlI5KM7:TR?= MkHENVA3QTh2M{[=
MKN-1 NUnMNohZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXTySXJbUUN3ME2wMlY1KM7:TR?= NV;pd4Y1OTB4OUi0N|Y>
PC14 NFTkUZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHHZ2FKSzVyPUGuPUDPxE1? NILsXYgyODZ7OESzOi=>
T24 MmftS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEXKS2lKSzVyPUCuOlQh|ryP MlezNVA3QTh2M{[=
U937 MYTGeY5kfGmxbjDBd5NigQ>? NH3sbIUzPCCq MoDpSG1UVw>? MnPKTY5pcWKrdIOgbY5kd3Kyb4LheIlwdiCxZjDbN2hefGi7bXnkbY5mKHerdHigTWM2OCCxZjCwMlEh|ryP NUXIV|ZpOTB5OEC5NVE>
H460pv8/eto NU\WcVRPS3m2b4TvfIlkKEG|c3H5 M2PJS|ExOCEQvF2= NYrGTo5TPDhiaB?= M{L2SnNidGmwZR?= NIrldFhKSzVyPUCuNFIh|ryP MX2xNFc5ODlzMx?=
H460pv8 NF34R3REgXSxdH;4bYMhSXO|YYm= MYKxNFAh|ryP MXG0PEBp NXfmNXVuW2GuaX7l M1nnV2lEPTB;MD6wNFQh|ryP NXnWSnQzOTB5OEC5NVM>
MDA-231 NHj1S3dEgXSxdH;4bYMhSXO|YYm= NHvQSY4yODBizszN M1fYUVQ5KGh? MUTTZYxqdmV? M3XEVGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KE2GQT2yN|Eh[2WubDCoSXIuNEWJRmKrMI12fGGwdDDwOVMqKHerdHigTWM2OCCxZjCwMlAxPiEQvF2= MVyxNFc5ODlzMx?=
MDA-468 NUjIfnBES3m2b4TvfIlkKEG|c3H5 M4jIfVExOCEQvF2= M2PiZVQ5KGh? NVHMPXBuW2GuaX7l NInMb3pEgXSxdH;4bYNqfHliYXfhbY5{fCCPRFGtOFY5KGOnbHygLGVTNSxiYX3wcIlncWWmIFXHSnItKG23dHHueEBxPTNrIIfpeIghUUN3MDDv[kAxNjByNTFOwG0> M1uyUFExPzhyOUGz
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M14 MmK1R5l1d3SxeHnjJGF{e2G7 MmPLNVAxKM7:TR?= NInQcIY1QCCq MYXHTVUxRTBwMUig{txO M4Xt[|I{QDdzOUC1
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NCI-H522 MWLDfZRwfG:6aXOgRZN{[Xl? Ml30NVAxKM7:TR?= M1vhRVQ5KGh? MoLuS2k2OD1yLkCzJO69VQ>? M4rhTlI{QDdzOUC1
OVCAR4 NUC4VYhXS3m2b4TvfIlkKEG|c3H5 MWixNFAh|ryP M{i4eVQ5KGh? MYrHTVUxRTBwM{eg{txO NELmPYgzOzh5MUmwOS=>
OVCAR5 NVK3cmRmS3m2b4TvfIlkKEG|c3H5 Mkf4NVAxKM7:TR?= NHXoT3Y1QCCq NILSdmxIUTVyPUCuOFEh|ryP NX\Q[5EzOjN6N{G5NFU>
OVCAR-8 NEH1coREgXSxdH;4bYMhSXO|YYm= NHPDUJIyODBizszN NF7QUm41QCCq NIPwbYVIUTVyPUCuNUDPxE1? MnXjNlM5PzF7MEW=
PRMI8226 M4\acmN6fG:2b4jpZ{BCe3OjeR?= MVexNFAh|ryP MVG0PEBp M4\qRmdKPTB;MD6wPEDPxE1? MWOyN|g4OTlyNR?=
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SF539 MkDxR5l1d3SxeHnjJGF{e2G7 NVfFO2RZOTByIN88US=> Ml[1OFghcA>? M3e2VmdKPTB;MD6xNkDPxE1? M3TySFI{QDdzOUC1
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UACC257 MXXDfZRwfG:6aXOgRZN{[Xl? NVLNT2dQOTByIN88US=> MW[0PEBp MlrwS2k2OD1yLkG0JO69VQ>? Mn;1NlM5PzF7MEW=
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H9c2 MVvGeY5kfGmxbjDBd5NigQ>? M1;0O|Uh|ryP NH7SSJkzPCCq NH7NU|BCdnSrb4jp[IFvfCCjY4Tpeol1gSCjc4Pld5Nm\CCjczDpcpRz[WOnbHz1cIFzKG2jbH;ufYxlcWGuZHXofYRmKGyndnXs Mm\FNlM6PzN{MUO=
H9c2 NVjlcHYzTnWwY4Tpc44hSXO|YYm= MofVOUDPxE1? M3vPPFI1KGh? MoL1RY51cW:6aXThcpQh[WO2aY\peJkh[XO|ZYPz[YQh[XNiaX70doFk\WyudXzhdkBTV1NibHX2[Yw> M36wZlI{QTd|MkGz
H9c2 NGLjSnRHfW6ldHnvckBCe3OjeR?= NG\6W2E2KM7:TR?= M2DPSFI1KGh? MlLGR4VtdHWuYYKgeZB1[Wun NVriR4d1OjN7N{OyNVM>
MCF7 NX\1SoFXTnWwY4Tpc44hSXO|YYm= NXLiZpRzPSEQvF2= MnjkNlQhcA>? Mm\rRY51cW:6aXThcpQh[WO2aY\peJkh[XO|ZYPz[YQh[XNiaX70doFucXSxY3jvcoRzcWGuIGLPV{Bt\X[nbB?= M37VUVI{QTd|MkGz
MCF7 MVXGeY5kfGmxbjDBd5NigQ>? NG[5O2o2KM7:TR?= MVOyOEBp NYjuZpNkS2WubIXsZZIhfXC2YXvl MWCyN|k4OzJzMx?=
MCF7 MY\GeY5kfGmxbjDBd5NigQ>? Mn\aOUDPxE1? MX6yOEBp NI\LZlFCdnSrb4jp[IFvfCCjY4Tpeol1gSCjc4Pld5Nm\CCjczDpcpRz[WOnbHz1cIFzKG2jbH;ufYxlcWGuZHXofYRmKGyndnXs NYrwcXlKOjN7N{OyNVM>
MCF7 MYXGeY5kfGmxbjDBd5NigQ>? NYLFR5pkPSEQvF2= NYnmSXBIOjRiaB?= M1uwVGNmdGy3bHHyJJVxfGGtZR?= NI\McJozOzl5M{KxNy=>
MDA-MB-231 MlTDSpVv[3Srb36gRZN{[Xl? MXG1JO69VQ>? MWWyOEBp NY\kdoU6S2WubIXsZZIhfXC2YXvl NWn5Vok6OjN7N{OyNVM>
MDA-MB-231 MUPGeY5kfGmxbjDBd5NigQ>? Ml7nOUDPxE1? MVuyOEBp NF;BbHNCdnSrb4jp[IFvfCCjY4Tpeol1gSCjc4Pld5Nm\CCjczDpcpRz[WOnbHz1cIFzKG2jbH;ufYxlcWGuZHXofYRmKGyndnXs MnnGNlM6PzN{MUO=
MDA-MB-231 NVXFUpB[TnWwY4Tpc44hSXO|YYm= M4nGcVUh|ryP MVGyOEBp MlLvRY51cW:6aXThcpQh[WO2aY\peJkh[XO|ZYPz[YQh[XNiaX70doFucXSxY3jvcoRzcWGuIGLPV{Bt\X[nbB?= MXuyN|k4OzJzMx?=
KB/HeLa MV\DfZRwfG:6aXOgRZN{[Xl? M1\BbFQ2KGh? M365c2VEPTB;MD6yOUDPxE1? MnPBNlM6QDh|NUG=
HUVEC NH;VdFVEgXSxdH;4bYMhSXO|YYm= M1e1c|Q5KGh? M{TPO2lEPTB;MD6wPFA4KM7:TR?= MlzRNlQxOTJ|N{i=
HepG2 M3:3[WZ2dmO2aX;uJGF{e2G7 MW[0NEDPxGdxbVy= MXG0PEBp MmnoSG1UVw>? NIW4NHZKdmirYnn0bY9vKG:oIGTST{B4cXSqIFnDOVAhd2ZiMD6wNFI2KM7:TR?= NGfMXokzPDBzM{SxNS=>
MRC5 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEPrR5A4OiCq M1LDOGlEPTB;MD6xJO69VQ>? NHG4[VYzPDB{MUS2Ni=>
HUVEC Mkj6SpVv[3Srb36gRZN{[Xl? NIPHfWE2KM7:TR?= M1vwOVIhcA>? M3XYTmNmdGy3bHHyJJVxfGGtZR?= M3TRdlI1ODJ6NES2
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LNcaP NWHrVppXTnWwY4Tpc44hSXO|YYm= NFTROWk{KM7:TR?= MVWyOEBp MYnJcoNz\WG|ZTDv[kBkdGWjdnXkJINie3Cjc3WtPUBt\X[nbB?= NGO5N3kzPDB7NUC4PS=>
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8305C MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTZ|LkGyJI5O M{fIenNCVkeHUh?=
IA-LM M1XMcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFjidnJKSzVyPU[zMlU1KG6P NYPwOpFUW0GQR1XS
HCC2157 NGHZV|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzwTWM2OD14Mz65OUBvVQ>? MV;TRW5ITVJ?
CTB-1 NIn5OG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HudGlEPTB;NkSwNVkhdk1? NUDsbFZ{W0GQR1XS
NCI-H1437 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7leHJmUUN3ME22OE43PCCwTR?= M1rrO3NCVkeHUh?=
U251 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUPRPHk1UUN3ME22OE45QSCwTR?= NVLlTldqW0GQR1XS
ALL-PO MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHLe2YxUUN3ME22OU4xOyCwTR?= MYrTRW5ITVJ?
NCI-SNU-1 NWTLdGtYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfSZWZKSzVyPU[1Mlg3KG6P MVLTRW5ITVJ?
RPMI-6666 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{n6[WlEPTB;NkWuPVkhdk1? MoX6V2FPT0WU
DBTRG-05MG NVzJVWFWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrSTWM2OD14Nz6xNUBvVQ>? MmPaV2FPT0WU
PF-382 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\QNWlEPTB;NkeuNVchdk1? NHe3UGxUSU6JRWK=
GT3TKB NXHCfVZNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnSwTWM2OD14Nz6xPUBvVQ>? MXPTRW5ITVJ?
SCC-3 NYizO2c1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV7JR|UxRTZ5LkK4JI5O MlXHV2FPT0WU
LU-134-A MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fU[mlEPTB;NkeuOlghdk1? MmKwV2FPT0WU
CAL-33 NV:zT2JET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn;RTWM2OD14Nz64O{BvVQ>? NFjH[ZFUSU6JRWK=
MC-IXC M1vIOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjTU|BKSzVyPU[3Mlkhdk1? Ml;0V2FPT0WU
CPC-N NYTjdW5JT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnxTWM2OD14OD60JI5O MmLHV2FPT0WU
A2780 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmWwTWM2OD14OD63PUBvVQ>? NYHPSZdNW0GQR1XS
Daudi NX;HZ4c2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE\LTm5KSzVyPU[4Mlk3KG6P M1\YPHNCVkeHUh?=
GI-1 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTZ7Lk[1JI5O NE\RPW1USU6JRWK=
SW962 NF2yVGFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlnmTWM2OD14OT65OUBvVQ>? M3u4WnNCVkeHUh?=
MFE-296 NUnVSpA6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIXJO|RKSzVyPUewMlQ6KG6P NVi4R|JMW0GQR1XS
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AN3-CA M3\GWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXzJR|UxRTd{LkOyJI5O NHzDNFdUSU6JRWK=
HCC1599 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVzk[4pNUUN3ME23Nk42PCCwTR?= Ml;zV2FPT0WU
HuCCT1 NHvyfoxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoS5TWM2OD15Mj65N{BvVQ>? NWrNenhDW0GQR1XS
Calu-1 NFvYc4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUHxXXQ4UUN3ME23N{43KG6P MnjnV2FPT0WU
DU-145 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX;oOI04UUN3ME23N{44OyCwTR?= M3r2SHNCVkeHUh?=
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HSC-3 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3frfGlEPTB;N{SuOVMhdk1? M2TI[nNCVkeHUh?=
HCC1806 M3XnU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjwTWM2OD15ND65OkBvVQ>? MnfxV2FPT0WU
VM-CUB-1 NIS1WVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHaXHJKSzVyPUe1MlM3KG6P NUfQRWVKW0GQR1XS
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NH-12 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHS4cXNKSzVyPUe2JI5O MkXMV2FPT0WU
MDA-MB-468 NGnicYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTd4LkG4JI5O NV\hUGFZW0GQR1XS
TUR MoCwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2HsTGlEPTB;N{[uN|Ihdk1? NYD6NHJnW0GQR1XS
TE-1 NXvVe3ZIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPpSo51UUN3ME23Ok4{PSCwTR?= M{SzVXNCVkeHUh?=
CMK M3K4NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TwfWlEPTB;N{euOFIhdk1? MUTTRW5ITVJ?
LB996-RCC NY\3V44yT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfMXFQ1UUN3ME23PE41PSCwTR?= Ml;wV2FPT0WU
NCI-H1650 NV;YbXV1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1Py[GlEPTB;N{iuOlIhdk1? MUXTRW5ITVJ?
DMS-273 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTd6Lkmgcm0> M1zPSXNCVkeHUh?=
NOS-1 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7PTWM2OD15OT6xOEBvVQ>? MmXmV2FPT0WU
NB69 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnnNm5KSzVyPUe5MlIhdk1? NHft[GtUSU6JRWK=
SUP-T1 Mmj6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTd7LkeyJI5O M2fMcnNCVkeHUh?=
A172 MmfFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3jpOWlEPTB;OECuOVUhdk1? M1HERnNCVkeHUh?=
TE-12 NGPqN3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFOxR|RKSzVyPUixMlA3KG6P M{foR3NCVkeHUh?=
MKN45 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGLMSYxKSzVyPUixMlUyKG6P MULTRW5ITVJ?
LoVo NXnzbJFFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTwfllVUUN3ME24NU45OiCwTR?= NHPoW5JUSU6JRWK=
SW1573 NFHE[WxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHlTWM2OD16Mj64NUBvVQ>? NUTURnJmW0GQR1XS
ETK-1 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Moe2TWM2OD16Mz6wNUBvVQ>? MVnTRW5ITVJ?
ABC-1 M2DG[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYHORWJGUUN3ME24N{41PSCwTR?= NVrtenJsW0GQR1XS
COLO-668 MlPjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlHuTWM2OD16ND60O{BvVQ>? Mlq5V2FPT0WU
UM-UC-3 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXvJR|UxRTh4LkCyJI5O Ml;PV2FPT0WU
BC-1 NWLVfm1xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoW1TWM2OD16Nj63OkBvVQ>? NVjJW2hMW0GQR1XS
PANC-10-05 NUi4[pRVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxRTh6LkS1JI5O NGPycFlUSU6JRWK=
ES3 MkD5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYHYTXNnUUN3ME24PU41QCCwTR?= NX6wUnlnW0GQR1XS
TE-441-T MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M171PGlEPTB;OEmuPFIhdk1? MkXqV2FPT0WU
KM-H2 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjqTWM2OD17MD62PEBvVQ>? NVPJRnRZW0GQR1XS
SH-4 NWK3Z2RwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlPYTWM2OD17Mj6xNUBvVQ>? MknDV2FPT0WU
SF268 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXrTWM2OD17Mj60NkBvVQ>? MmOzV2FPT0WU
VMRC-RCZ M1fI[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH[1eJJKSzVyPUmzMlI3KG6P NHzze2ZUSU6JRWK=
GI-ME-N MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTl|LkOzJI5O MYHTRW5ITVJ?
JEG-3 NWDtOFVVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnPYTWM2OD17NT6xNkBvVQ>? NXX3Oph4W0GQR1XS
J-RT3-T3-5 NX3ES|RnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MontTWM2OD17Nj6zNUBvVQ>? MnfNV2FPT0WU
K5 M{W2XWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTl4Lkmgcm0> MkTvV2FPT0WU
EFO-27 NFHSS2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXKU5ZEUUN3ME25O{41PCCwTR?= NYjYUlBrW0GQR1XS
SW1783 M{H2NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIryd|FKSzVyPUm3Mlk6KG6P NIj6bI9USU6JRWK=
CAL-39 NVe0[lA4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjJbmRKSzVyPUm4MlI1KG6P M2LUeHNCVkeHUh?=
LS-441N MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NInFe4xKSzVyPUm5MlA3KG6P M3GxPXNCVkeHUh?=
G-402 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3PDdmlEPTB;OUmuNFkhdk1? MlP1V2FPT0WU
MES-SA MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvDU4tKSzVyPUm5MlU{KG6P NGrvdphUSU6JRWK=
FADU NHXpT2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTFyMj6xPEBvVQ>? M1TpO3NCVkeHUh?=
DJM-1 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3\wXWlEPTB;MUCyMlI2KG6P NFjsVWVUSU6JRWK=
SU-DHL-1 M3\mVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{m5cGlEPTB;MUCyMlUhdk1? MmXZV2FPT0WU
KYSE-410 NF;FVo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEXuN4NKSzVyPUGwN{41PiCwTR?= NG[3UohUSU6JRWK=
NCI-H1618 NH;tcFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWXJR|UxRTFyND6zOUBvVQ>? MXfTRW5ITVJ?
AU565 MmXUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUXJR|UxRTFyND61NUBvVQ>? NU\vSWVTW0GQR1XS
SF126 NHTBPINIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;kelZKSzVyPUGwOE42QCCwTR?= NVqyTXR[W0GQR1XS
MMAC-SF M4SxN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml\aTWM2OD1zME[uOFghdk1? MXXTRW5ITVJ?
ChaGo-K-1 NIC2ZZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVmwcIJSUUN3ME2xNFcvQTVibl2= M{X2bHNCVkeHUh?=
NCI-H596 MoTVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDRVGhtUUN3ME2xNFgvODFibl2= MnK0V2FPT0WU
LXF-289 Mn;CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDxZXJ{UUN3ME2xNFkvOjRibl2= MWPTRW5ITVJ?
HCC1569 NUjub3pST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHm1VJNKSzVyPUGwPU4{PCCwTR?= NV[4bXUxW0GQR1XS
NCI-H2170 MnP5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjrTWM2OD1zMEmuPVIhdk1? NFfYU2pUSU6JRWK=
ARH-77 M{HUeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\JflJXUUN3ME2xNFkvQTlibl2= M3O3enNCVkeHUh?=
BOKU MkLBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF\adWdKSzVyPUGxNE45PyCwTR?= NIWzPYpUSU6JRWK=
SJSA-1 NWHCbVRxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWTJR|UxRTFzMT6wOUBvVQ>? MmqwV2FPT0WU
SW626 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXTCSGQ2UUN3ME2xNVEvPzFibl2= NYnyTWFpW0GQR1XS
EHEB MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfJU4dMUUN3ME2xNVIvPTlibl2= M1y5T3NCVkeHUh?=
TE-10 M4q0N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3QNohTUUN3ME2xNVIvPjhibl2= MkTQV2FPT0WU
MZ7-mel M2LPeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEn1[o5KSzVyPUGxNk45PCCwTR?= M3LNdHNCVkeHUh?=
SAS NXfNUVR{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4jjNmlEPTB;MUG0MlQ2KG6P MkLQV2FPT0WU
TK10 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4rYUmlEPTB;MUG0MlYhdk1? NVmz[ok{W0GQR1XS
SW13 NWjIfWNbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxRTFzNT6yOkBvVQ>? MX3TRW5ITVJ?
HCC1937 M3HNPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTFzNT64OEBvVQ>? NGjyZYVUSU6JRWK=
SK-NEP-1 NWDLPW1UT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYPkbnpFUUN3ME2xNVYvOjZibl2= NIPER4xUSU6JRWK=
OVCAR-5 NVLqV|ZWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUL1dJpCUUN3ME2xNVYvQDFibl2= MX\TRW5ITVJ?
SW837 NEPBT2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXS2fJRxUUN3ME2xNVcvQTVibl2= MUjTRW5ITVJ?
BFTC-909 M{Tqc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{LONWlEPTB;MUG4MlQ5KG6P MV;TRW5ITVJ?
SW872 M3jKd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfKdpdOUUN3ME2xNlAvQDFibl2= NUXpV|hXW0GQR1XS
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MLMA NG\kNI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXnuXnFJUUN3ME2xNlIvODhibl2= NUTUR2RsW0GQR1XS
BL-41 MmPPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MU\JR|UxRTF{Mj6yNkBvVQ>? NXL2[XNjW0GQR1XS
LB647-SCLC NFfRZ3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfvTWM2OD1zMkOuN|Uhdk1? NHn5TmdUSU6JRWK=
NCI-H1703 M1j0[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkK1TWM2OD1zMk[uOFIhdk1? M1PBSnNCVkeHUh?=
KURAMOCHI M1vBcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlfXTWM2OD1zMk[uO|Yhdk1? MnOzV2FPT0WU
ATN-1 NFrZXJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTF{Nz63JI5O MVfTRW5ITVJ?
SK-CO-1 M2DMdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojUTWM2OD1zMkmuNlEhdk1? M{nsPHNCVkeHUh?=
RPMI-7951 NXzScYJqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rZR2lEPTB;MUOwMlE1KG6P MmD6V2FPT0WU
NCI-H1648 NFWwcmJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH3qXFBKSzVyPUGzNU46PCCwTR?= MlfTV2FPT0WU
NCI-H64 NXuyRoF{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWrDb3dxUUN3ME2xN|IvPjVibl2= Mn\NV2FPT0WU
HT-3 NEHsNIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlv1TWM2OD1zM{OuNFQhdk1? M3vGXnNCVkeHUh?=
NCI-H1770 NXzuZYd6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3VUXNLUUN3ME2xN|MvOjFibl2= NXXhflhDW0GQR1XS
NB13 NWjSSW9nT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEexdoNKSzVyPUGzOE42PSCwTR?= MkD6V2FPT0WU
NCI-H747 NVPuOFF4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRTF|NT6wNkBvVQ>? NYrzfXRMW0GQR1XS
ML-2 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHLkUXlKSzVyPUGzOU4yPiCwTR?= NH;s[nNUSU6JRWK=
CA46 NY\0VVB4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHWzOGJKSzVyPUGzOk45QCCwTR?= NVHmTo9UW0GQR1XS
ES6 M1[5dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1L2SmlEPTB;MUO3MlEzKG6P M4W3TnNCVkeHUh?=
JiyoyeP-2003 NITiVpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVTJR|UxRTF|Nz64JI5O Mn\SV2FPT0WU
NMC-G1 NVHpO2FMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTF|OT6xN{BvVQ>? M2T1UXNCVkeHUh?=
U-698-M NFXjfJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIT0cG9KSzVyPUGzPU42KG6P NGm1dlFUSU6JRWK=
LU-99A M1GyNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7TTWM2OD1zNE[uOVUhdk1? Mn\2V2FPT0WU
NCI-H748 M4rGPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTF2Nz6zNUBvVQ>? NI[xenpUSU6JRWK=
SK-MEL-3 M3PCVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHvfGVKSzVyPUG0O{43OSCwTR?= NYnX[YF3W0GQR1XS
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PANC-08-13 NIfB[mJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYDuV2gxUUN3ME2xMlY{ODh2IN88US=> MlvwV2FPT0WU
D-542MG Mn;NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFK3cWFKSzVyPUGuOlU{ODVizszN MVvTRW5ITVJ?
LC-1F NIDB[GxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4L6UWlEPTB;MT62OlIxOyEQvF2= MmjoV2FPT0WU
KP-N-YN M2nRbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3q4O2lEPTB;MT62OlM1OyEQvF2= NG\PXHFUSU6JRWK=
MFE-280 NUn2WFh6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjxTWM2OD1zLk[2PFEzKM7:TR?= MULTRW5ITVJ?
S-117 NXnGbFNHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoKxTWM2OD1zLkewOVA1KM7:TR?= MlnmV2FPT0WU
NCI-H1573 NUDKPXNsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFrxcWJKSzVyPUGuO|E4OzNizszN NH;XbohUSU6JRWK=
BT-20 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlnHTWM2OD1zLke0NFY5KM7:TR?= M2iyPXNCVkeHUh?=
NCI-H28 MmO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFSwSnVKSzVyPUGuO|QxPzhizszN NWXGcG5RW0GQR1XS
CaR-1 M1frfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTFwN{izNlQh|ryP M3TIXHNCVkeHUh?=
LN-405 NVjPNGJKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjKeW8yUUN3ME2xMlgxOTR|IN88US=> NULkV5RLW0GQR1XS
RT4 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXHJR|UxRTFwOES0NVch|ryP NFLrT4JUSU6JRWK=
NCI-H889 MmDMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjMTZozUUN3ME2xMlk{QDh4IN88US=> NUnwPWEzW0GQR1XS
SW1463 M2nxWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETWfHBKSzVyPUGuPVU4ODFizszN NH3IWYFUSU6JRWK=
SCLC-21H MoXrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\zTWM2OD1{LkCwOlI1KM7:TR?= NXPQVZU6W0GQR1XS
CP66-MEL M2rwcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{HVSWlEPTB;Mj6wNVc3PyEQvF2= NWLjZ|UxW0GQR1XS
Hs-578-T MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3L1bmlEPTB;Mj6wNVc5OiEQvF2= MUDTRW5ITVJ?
HCC70 MlqxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTJwMEW0OlMh|ryP NGG2N3ZUSU6JRWK=
SW1088 NUT4b|dQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rkN2lEPTB;Mj6wOlk{OSEQvF2= MYLTRW5ITVJ?
NB6 M4iwfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2r5OWlEPTB;Mj6xPFUh|ryP MYrTRW5ITVJ?
KU-19-19 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3jsTGlEPTB;Mj6yOlkyPyEQvF2= NVTLXnMxW0GQR1XS
A704 Ml\LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGj1N2NKSzVyPUKuNlkyOzVizszN NXnhdZJYW0GQR1XS
EVSA-T M2fCTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX7PXm5wUUN3ME2yMlMxODh7IN88US=> NHPmZVdUSU6JRWK=
HCT-15 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvDTWM2OD1{LkO1OFY3KM7:TR?= MUHTRW5ITVJ?
HuO-3N1 NIqyUXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHj0TFZKSzVyPUKuN|Y2QDNizszN NVfuTmwyW0GQR1XS
GMS-10 NUK3UZBCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIn6TZNKSzVyPUKuN|k4OzhizszN NF\LO5FUSU6JRWK=
TGBC24TKB NGXQblNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFn5eFRKSzVyPUKuOFE1OjlizszN MV3TRW5ITVJ?
C2BBe1 MmnxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvaNHp5UUN3ME2yMlUyOzJ6IN88US=> MXrTRW5ITVJ?
SK-N-DZ NFnxXYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnnGTWM2OD1{LkW2OVkzKM7:TR?= NXzDWVExW0GQR1XS
SK-N-AS NFXyWHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3HvdWlEPTB;Mj63N|AyPSEQvF2= M1TKbHNCVkeHUh?=
T98G MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlPPTWM2OD1{LkiwOFAyKM7:TR?= MVTTRW5ITVJ?
DMS-79 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3P1OmlEPTB;Mj65NFk5QCEQvF2= NULjSJVFW0GQR1XS
SNU-475 MkXNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{TON2lEPTB;Mj65NlU4OiEQvF2= NIe5[ZZUSU6JRWK=
COLO-792 MnKyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH25dHZKSzVyPUOuNFI5PyEQvF2= M1XGU3NCVkeHUh?=
YAPC MnLZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIDpUIlKSzVyPUOuN|I5OzJizszN MWDTRW5ITVJ?
UACC-812 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTNwM{O3N|gh|ryP M1LKV3NCVkeHUh?=
Mewo NXPQT3dCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NILIeHBKSzVyPUOuOFYxQDZizszN NH;VNphUSU6JRWK=
COLO-824 NVjkdpZOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUHJR|UxRTNwNUezO|gh|ryP NWLzWJp2W0GQR1XS
SCC-9 M2O4fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTNwOUGzNFkh|ryP MVTTRW5ITVJ?
CP50-MEL-B MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmG3TWM2OD1|Lkm4O|A{KM7:TR?= MUjTRW5ITVJ?
NCI-H345 NU\XZW1mT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTDU4V6UUN3ME20MlAyOTd2IN88US=> Ml\SV2FPT0WU
COR-L88 NVTzWmNnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1uyRmlEPTB;ND6zPVU5KM7:TR?= M{juOnNCVkeHUh?=
RCM-1 M1\6bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkPXTWM2OD12LkS5NlczKM7:TR?= M{ji[nNCVkeHUh?=
JVM-3 Mn7nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHLJN4hKSzVyPUSuOlA3OThizszN MkPPV2FPT0WU
ECC4 MkPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnXS|dKSzVyPUSuO|Y2PDFizszN MWnTRW5ITVJ?
MDA-MB-453 NHjnXFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\TTWM2OD12Lki1NVM1KM7:TR?= M1PRfXNCVkeHUh?=
SK-N-FI MoHhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPmTWM2OD13LkKyPFc4KM7:TR?= NY\tcm5jW0GQR1XS
D-502MG MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVTJR|UxRTVwMkSyOlIh|ryP NYrROodkW0GQR1XS
NCI-H2227 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmnDTWM2OD13LkO2NlMyKM7:TR?= NXi1b|d[W0GQR1XS
DMS-53 M{\nO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVzOXVZ7UUN3ME22MlE4OTB4IN88US=> NIDaPGlUSU6JRWK=
LB771-HNC NWTOe2M4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRTZwNE[4NFYh|ryP NHHKfoxUSU6JRWK=
BB49-HNC NGLwT4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1i0d2lEPTB;Nz60NVc6OSEQvF2= NFHPOVFUSU6JRWK=
MDA-MB-415 NEXwc3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3HF[WlEPTB;Nz61O|MxOyEQvF2= MYDTRW5ITVJ?
TALL-1 NELxUXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlLoTWM2OD15Lkm2PFgh|ryP NGrqTIxUSU6JRWK=
HCC1395 NYrmToNST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnL5TWM2OD16LkG1NVIzKM7:TR?= M3TVVXNCVkeHUh?=
EFE-184 MlLpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1XNbWlEPTB;OD6zO|IyPiEQvF2= NFO0OnpUSU6JRWK=
EC-GI-10 M3fxTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmK0TWM2OD16Lk[4Olg3KM7:TR?= MkTmV2FPT0WU
TT M13Ebmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTlwME[5OlYh|ryP MonXV2FPT0WU
U-2-OS NHrnT4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTlwOEGzPVMh|ryP MUjTRW5ITVJ?
SHP-77 NG\LeHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH\scoNKSzVyPUmuPVAzQSEQvF2= MUTTRW5ITVJ?
HCC1143 NGHBcYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXu2PGxSUUN3ME2xNE41Pzl5IN88US=> NHrCRlFUSU6JRWK=
A498 NW\WdWpFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTF6LkK5O|Yh|ryP NWHHTHlTW0GQR1XS
LS-513 Ml;hS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\NW2lEPTB;MUiuOlA6OyEQvF2= NILGdmJUSU6JRWK=
K052 M{L1e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTJzLkS0NVgh|ryP NIrPRXpUSU6JRWK=
SiHa M3PKPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljBTWM2OD1{Mz6zN|cyKM7:TR?= MYDTRW5ITVJ?
RCC10RGB NF3MN25Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVPJR|UxRTNyLkC2NVEh|ryP NHLvXWdUSU6JRWK=
NCI-SNU-16 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTNzLkG4N|Yh|ryP NHzpRmxUSU6JRWK=
SNU-C1 NXPke3BxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjKWZZKSzVyPUOyMlQyPzVizszN NVXafVZyW0GQR1XS
C32 MlztS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\DTWM2OD1|Mj64O|Ih|ryP NIXkSWtUSU6JRWK=
SW684 MnLhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\xcpFKSzVyPUO0MlE2PjFizszN NH7uVVBUSU6JRWK=
SK-MEL-28 M{T3VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTN3LkWzO|ch|ryP NIfJ[5JUSU6JRWK=
SK-MEL-1 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTN4Lke1OFch|ryP MY\TRW5ITVJ?
NCI-H720 M1rVV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2K0TmlEPTB;NEGuPVczPiEQvF2= M1r3UHNCVkeHUh?=
P31-FUJ Mk\QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEPmTXZKSzVyPUS0MlMzQDRizszN M4HjT3NCVkeHUh?=
NCI-H524 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXnLW5Q2UUN3ME20PE45OjR6IN88US=> NILPNWJUSU6JRWK=

他の多くの細胞株試験データをご覧になる場合はこちらをクリックして下さい

体内試験 In vivo, Doxorubicin in combination with adenoviral MnSOD (AdMnSOD) plus 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) has the greatest effect in decreasing the volumes of MB231 tumors and prolonging survival of mice. [1] Although its use is limited by the chronic and acute toxic side effects it produces, Doxorubicin is essential in treating breast and oesophageal carcinomas, solid tumours in childhood, osteosarcomas, Kaposi's sarcoma, soft tissue sarcomas, and Hodgkin and non-Hodgkin lymphomas. [2]

お薦めの試験操作(参考用のみ)

動物試験:[1]
+ 展開
  • 動物モデル: Female athymic nude mice injected s.c. with MB231 cells
  • 製剤: Dissolved in DMSO, and diluted in saline
  • 投薬量: 3 mg/kg/day
  • 投与方法: Delivered intratumorly
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 100 mg/mL (172.41 mM) warming
Water 20 mg/mL (34.48 mM)
Ethanol Insoluble

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報

分子量 579.98
化学式

C27H29NO11.HCl

CAS No. 25316-40-9
保管
in solvent
別名 NSC 123127

便利ツール

モル濃度計算器

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (g) = 濃度 (mol/L) x 体積 (L) x 分子量 (g/mol)

モル濃度計算器方程式

  • 質量
    濃度
    体積
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 入力 出力 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量 濃度 体積 分子量

臨床試験

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03036904 Not yet recruiting Diffuse Large B-Cell Lymphoma|High Grade B-Cell Lymphoma Weill Medical College of Cornell University|Genentech, Inc.|Massachusetts General Hospital|M.D. Anderson Cancer Center February 6, 2017 Phase 1
NCT02659930 Recruiting Kaposi Sarcoma National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC) January 4, 2016 Phase 1
NCT03042819 Not yet recruiting Soft Tissue Sarcoma University Health Network, Toronto|Karyopharm Therapeutics, Inc March 27, 2017 Phase 1
NCT03033914 Recruiting Hodgkin Lymphoma Memorial Sloan Kettering Cancer Center|Bristol-Myers Squibb|M.D. Anderson Cancer Center|City of Hope Medical Center January 25, 2017 Phase 1
NCT02957968 Recruiting Locally Advanced Breast Cancer|Invasive Adenocarcinoma of the Breast|Breast Cancer Stage II|Breast Cancer Stage III|Breast Cancer Stage IV Virginia Commonwealth University|Merck Sharp & Dohme Corp.|National Cancer Institute (NCI) January 24, 2017 Phase 2
NCT02377752 Active, not recruiting Neoplasm Eli Lilly and Company March 23, 2015 Phase 1

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

  • * 必須

よくある質問(FAQ)

  • 質問1:

    Why the IC50 of the compound varied over time in our measurement?

  • 回答:

    Sometimes the IC50 value might vary between different batch of compounds due to the slight differences in purity. If different IC50 was seen in the same batch of compound, the problem may lies in the process of dissolvement. Make sure that you see no particles and the solution is clear with your stock solution.

Topoisomeraseシグナル伝達経路

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