MG-132

製品コードS2619

MG-132化学構造

分子量(MW):475.62

MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.

サイズ 価格(税別)  
JPY 8300.00
JPY 28220.00
JPY 78020.00

Selleckは効果が一番いいである(S,R,S)-(-)-2のコンフィギュレーションを採用しましたので、MG-132プロテアソームの抑制効果はSigmaの同類製品の効果より著しく高くなります

正常には、p21蛋白はユビキチン化で分解されますが、MG-132はプロテアソームの活性を抑制することを通じて、p21蛋白の貯まりを引き起こします。だから、MG-132の抑制効果は強ければ強いほど、p21蛋白の貯まりは多くなってきます。(検査された蛋白:p21  細胞株:HeLa细胞株 処理条件:濃度5μM 処理時間:6h)

文献中の使用例(47)

カスタマーフィードバック(10)

  • MDA-MB-231 cells were treated with 10 uM MG132 and incubated under normoxia or hypoxia for 4 h. Endogenous interaction between LATS2 and SIAH2 was analysed by immunoprecipitation.

    Nat Cell Biol 2015 17(1), 95-103. MG-132 purchased from Selleck.

    HeLa cells were transfected with control mimic, RMND5A siRNA or miR-138 mimic. After transfection for 36 h, cells were treated with proteasome inhibitor MG132 (20 uM) or Dimethyl sulfoxide (DMSO) for 8 h. Endogenous Exportin-5 protein and RMND5A protein expression was measured by western blotting.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

  • HeLa cells were transfected with negative control mimic, miR-138 mimic or RMND5A siRNA. After transfection for 36 h, cells were treated with MG132 (20 uM) or DMSO for 8 h. RMND5A and Exportin-5 protein expression were analyzed by immunocytochemistry. Nuclei were counterstained with DAPI.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

     

    TFEB induced autophagy dependent ATZ clearance in vitro. MEF transiently co-transfected with either ATZ plus GFP expressing plasmids or ATZ plus TFEB expressing plasmids were incubated with proteasome inhibitor MG132 or with DMSO for 6 h. Upon MG132 treatment, steady state levels of 52 kDa ATZ band increased in both cells transfected with ATZ plus GFP and with ATZ plus TFEB expressing plasmids. Quantification of band intensities showed a 48% reduction of ATZ in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP, in the absence of the proteasome inhibitor. In MG132 treated cells, a 61% decrease of ATZ was detected in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP.

    EMBO Mol Med 2013 5, 397-412. MG-132 purchased from Selleck.

  • JAK1 expression was analyzed in A375 cells expressing scrambled shRNA or shRNF125 (#2) and treated with MG132 (5 uM, 10 hr), and in Lu1205 cells expressing WT RNF125 and treated with MG132.

    Cell Rep 2015 11(9), 1458-73. MG-132 purchased from Selleck.

    LRB1 and LRB2 regulate phyB protein levels. PhyB protein levels in crude extracts from the wild type (WT) and the indicated mutant backgrounds were assayed by immunoblot analysis with anti-phyB monoclonal antibodies. Anti-PBA1 and anti-histone H3 antibodies were used to confirm equal protein loading. Rc-induced loss of phyB in the wild type is inhibited by 100 uM MG132.

    Plant Physiol 2012 60(1), 118-34. MG-132 purchased from Selleck.

  • Representative images for γ-H2AX-stained cells treated with 100 uM FA for 3 h without or with MG132. Fluorescence was measured in at least 50 nuclei in each of three experiments.

    Toxicol Appl Pharmacol 2015 286(2), 135-41. MG-132 purchased from Selleck.

    GSK-3β phosphorylation at Ser9 is enhanced in NOK-overexpressed stable cell lines. The proteasome inhibitor, MG132, was added in medium of HeLa-HA and HeLa-NOK-HA cells for 12 h and then the p-GSK-3b(Ser9) was assayed by western blotting.

    FEBS Lett 2012 586, 3787–3792. MG-132 purchased from Selleck.

  • Nek2A impedes SuFu ubiquitination. HEK293T cells transfected with Nek2A-Myc and Flag-SuFu for 48 h were treated with MG-132 to enrich ubiquitinated proteins, and subsequently subjected to co-immunoprecipitation assay. Precipitated proteins were probed using anti-Ub antibody.

    Int J Oncol, 2017, 50(2):373-380. MG-132 purchased from Selleck.

    Truncated mouse Period2 (Per2) protein was expressed in NIH3T3 cells, treated by cycloheximide with or without MG132 for 1-4 hours.Per2 was reported to be degraded by the proteasome proteolysis. By adding MG132 (25 μM), a proteasome inhibitor, the degradation of Per2 was dramatically decreased within 4 hours treatment (shown by western blot).

    2012 Dr. Edison DUKE-NUS Graduate Medical School Singapore.. MG-132 purchased from Selleck.

質量管理及び製品安全説明書

Proteasome阻害剤の選択性比較

生物活性

製品説明 MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.
ターゲット
20S proteasome [9]
(Cell-free assay)
100 nM
体外試験

MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM. MG-132 also inhibits calpain with IC50 of 1.2 μM. MG-132 induces neurite outgrowth in PC12 cells at an optimal concentration of 20 nM, displaying 500 times more potency than ZLLal. [1] MG-132 (10 μM) potently inhibits TNF-α-induced NF-κB activation, interleukin-8 (IL-8) gene transcription, and IL-8 protein release in A549 cells by inhibition of proteasome-mediated IκBα degradation. [2] MG-132 treatment potently induces p53-dependent apoptosis in KIM-2 cells by 26S proteasome inhibition. [3] Unlike BzLLLCOCHO or PS-341, MG-132 treatment results in weak inhibition of the chymotrypsinlike (CT-L) and peptidylglutamyl peptide hydrolysing (PGPH) activities of the 26S proteasome, whereas multiple myeloma cells (U266 and OPM-2) are more sensitive to induction of apoptosis by MG-132 than BzLLLCOCHO. [4] MG-132 (1 μM) sensitizes TRAIL-resistant prostate cancer cells by activating the AP-1 family members c-Fos and c-Jun, which, in turn, repress the antiapoptotic molecule c-FLIP(L). [5] MG-132 significantly enhances the ability of inositol hexakisphosphate (IP6) to reduce cellular metabolic activity in both PC3 and DU145 androgen-independent prostate cancer (AIPCa) cell lines. [6]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
LPS-stimulated RAW264.7 cells MoPCSpVv[3Srb36gRZN{[Xl? NIHSU28zPSEQvF2= Mn;6SG1UVw>? M2XwcWlvcGmkaYTzJI5qfHKrYzDvfIll\SCycn;keYN1cW:wIIfpeIghUUN3MDDv[kAxNjFizszN MoT5NlQ3QTd2OU[=
HL-60 NEfMZ5hEgXSxdH;4bYMhSXO|YYm= MWq0NEDPxE1? M1rhd|Q5KGh? M3foOWROW09? NYS3UIxZUUN3MEyxNEDPxE1? NUCwWlk6OjR4OUe0PVY>
SMMC-7721 NGXo[YREgXSxdH;4bYMhSXO|YYm= M1[0[lQxKM7:TR?= MkHTOFghcA>? MVjEUXNQ MmDCTWM2OD15LkGg{txO MWKyOFY6PzR7Nh?=
A-549 MVPDfZRwfG:6aXOgRZN{[Xl? Mo\MOFAh|ryP MXW0PEBp NHvC[mFFVVOR NGP5RlFKSzVyPEGwJO69VQ>? NE\MSXAzPDZ7N{S5Oi=>
MCF-7 NIKwc4xEgXSxdH;4bYMhSXO|YYm= Ml\xOFAh|ryP NV3keY1zPDhiaB?= NGDhXYZFVVOR MnvuTWM2OD15LkOg{txO NHXnR4ozPDZ7N{S5Oi=>
SW-480 M3XuOWN6fG:2b4jpZ{BCe3OjeR?= NIe4fpU1OCEQvF2= MofLOFghcA>? NGD3NJZFVVOR NEnsbIZKSzVyPUSg{txO MXWyOFY6PzR7Nh?=
NCI-H929 NWexOY02S3m2b4TvfIlkKEG|c3H5 MU[xJO69VQ>? NITNW4w4OiCq NGrDfWRFVVOR M2H1fmlEPTB;MD6xO{DPxE1? NWTNWXlbOjR4MkWwPFg>
293T NFvncnlEgXSxdH;4bYMhSXO|YYm= NWLqT5lzOTBizszN NVThWpI3PzJiaB?= Mk\LSG1UVw>? NWHFOZJ7UUN3MEyyJO69VQ>? NIPWe|MzPDZ{NUC4PC=>
293T M2LibmZ2dmO2aX;uJGF{e2G7 NH71TYUyOCEQvF2= MXiyOEBp MVPEUXNQ M3vMU21w\GW{YYTlcJkhcW6mdXPld{Bp\WG2LYPoc4NsKCB? M3vwdFI1PjJ3MEi4
HeLa NHqwdlhMcW6jc3WgRZN{[Xl? MXKxNEDPxE1? M1[5NFEhcA>? MV;EUXNQ MkHFTY5lfWOnczDQRXJRKGOuZXH2ZYdmKGK7IHnubIljcXSrbnegdJJwe2Wjc3;t[UBi[3Srdnn0fS=> Mme1NlQ{OjF6M{O=
MDA-MB-231 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmSxNUDPxE1? NEf6eFc4OiCq MmDvSG1UVw>? NFPzZ4tKSzVyPUCuNVgh|ryP MUSyOFE2OzJyNh?=
MCF-7 NF7XPXdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{X6bVEh|ryP MkXuO|IhcA>? MVnEUXNQ NXzoRZlQUUN3ME2wMlE{KM7:TR?= M{G1b|I1OTV|MkC2
MCF10A M2TpTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGDRd|cyKM7:TR?= NYHSNnVGPzJiaB?= NYX3eGdSTE2VTx?= M1[zUWlEPTB;MD6yPUDPxE1? NVzrN4lROjRzNUOyNFY>
HEK-293 MXrLbY5ie2ViQYPzZZk> MV[yJIFv\CB{MDFOwG0> MWKyJIg> MXrEUXNQ MnH3TY5pcWKrdIOgR4hVNUxiYXP0bZZqfHlid3n0bEBKSzVyIH;mJFkhdk1i MYGyN|U1ODd7MB?=
Calu6 MWrGeY5kfGmxbjDBd5NigQ>? NX3wS|A5OTBizszN NWXsV5A6OThiaB?= NVzaTnpmTE2VTx?= NEjJemJUcWewaX\pZ4FvfGy7IHHjZ5VufWyjdHXzJIZz[XSjeHnuJJBz\WO3coPvdi=> NEDBZ|kzOzVyNkS4Oi=>
IFN-gamma-induced RAW264.7 NIi5SHBHfW6ldHnvckBCe3OjeR?= MXvEUXNQ MXHJcohq[mm2czDubZRzcWNib4jp[IUheHKxZIXjeIlwdiC5aYToJGlEPTBib3[gNE4xPzdizszN Mn25NlIzPzd{N{e=
IPC227F MUfDfZRwfG:6aXOgRZN{[Xl? MV6xJO69VQ>? NV;Dd5RQPDhiaB?= M3jFWGROW09? NW\YflF[UUN3ME2wMlA4PyEQvF2= MnXNNlE6OjR3Mki=
Hepa-1c1c7 MoDxSpVv[3Srb36gRZN{[Xl? MWSyOUDPxE1? Mo\sOkBp NEnqOlNFVVOR M{XPPWlv[3KnYYPld{BPemZ{IIDyc5RmcW5ibHX2[Yw> NH7BOmczODN7MkW0OC=>
COS-7 MYXDfZRwfG:6aXOgRZN{[Xl? NWnRRWIxOTBizszN MWfEUXNQ M3zZTmlEPTB:MUCg{txO M2q5SVE5ODh6MEm3
HuH-7 NFe3bpVEgXSxdH;4bYMhSXO|YYm= NHracIUyOCEQvF2= M3PTNmROW09? MWLJR|UxRDFyIN88US=> Mn\UNVgxQDhyOUe=
OCI-Ly3 NFT3fFhHfW6ldHnvckBCe3OjeR?= MX:xNEDPxE4EoB?= M3zxdFQhcA>? Mli4SG1UVw>? NXnGclhuUW6mdXPld{BpfW2jbjDJb4FxeGGEYXzwbIEhe3SjYnnsbZpifGmxbjD3bZRpKEWFNUCgc4YhOSEQvF2= NFT3VWkyQDB{NEGxNy=>
A2780 cDDP NVq3[JF4SXCxcITvd4l{KEG|c3H5 M3zYNVI1KGh? NYfkcZd7TE2VTx?= NVHOSoFEUW6mdXPld{BieG:ydH;zbZMh[nliaX7obYJqfGmwZzDQWGVPKGSnZ4Lh[IF1cW:w Mn[4NVc3QDRyMUi=
LPS-stimulated RAW264.7 cells M2XBWmZ2dmO2aX;uJGF{e2G7 MofFSG1UVw>? Ml63TY5pcWKrdIOgUmYuc2GycHHCJGRPSSCkaX7kbY5o MlnXNVc1ODd{N{e=
PC12 M2e1S2Z2dmO2aX;uJGF{e2G7 NY\NV3RvOTByIN88UeKh NYLDcFhIOjRiaB?= NHfpeYhFVVOR MVTJcohq[mm2czC2MW9JTEFvIHHu[EBJOk9{LXnu[JVk\WRiY4n0c5RwgGmlaYT5 NHXQbnIyPzF3OES1OC=>
PC3 MlvHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXuyNEDPxE1? NGXBVHM1QCCq MYTEUXNQ NY[wSppjUUN3ME2wMlYh|ryP M4XLbVE3Pjh4NUO3
LP-1 NX3JfXZxSXCxcITvd4l{KEG|c3H5 M1LD[FMxOCCwTR?= NWe3c29SOjRiaB?= NFfSWWpFVVOR MoPSTY5lfWOnczDhdI9xfG:|aYOgZpkhcW6lcnXhd4lv\yClbHXheoVlKFCDUmCgcIV3\WxiYX7kJJJm\HWlaX7nJG1kdC1zIIDyc5RmcW5ibHX2[Yw> MnvMNVU6PTh3OEm=
ES6 Mmn1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfCS5JKSzVyPUCuNFE{ODZizszN MULTRW5ITVJ?
A101D NH3CemtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\4TWM2OD1yLkCzNlc6KM7:TR?= NInQSWNUSU6JRWK=
OCUB-M M2jO[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4C3dGlEPTB;MD6wN|c{PyEQvF2= NHfGOWFUSU6JRWK=
LB2518-MEL MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;jeG9UUUN3ME2wMlA{PzZizszN NIrhcXlUSU6JRWK=
SH-4 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTBwMESzNUDPxE1? NHSwTlJUSU6JRWK=
KNS-42 NVLBN3dsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjoWGt3UUN3ME2wMlA1PDRzIN88US=> NF;hVZpUSU6JRWK=
DSH1 MoHrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWHqOIdnUUN3ME2wMlA2Ojh7IN88US=> NXfIN5ZvW0GQR1XS
NTERA-S-cl-D1 NYnZOo82T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF63N2xKSzVyPUCuNFU4PzJizszN NYrne4h6W0GQR1XS
D-542MG MlnJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MonITWM2OD1yLkC1PVU4KM7:TR?= NEHtcmRUSU6JRWK=
KS-1 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoPNTWM2OD1yLkC2OFU5KM7:TR?= Mn62V2FPT0WU
BL-41 MlPPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HafmlEPTB;MD6wOlk1PyEQvF2= NVTUSW9OW0GQR1XS
LXF-289 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mkf4TWM2OD1yLkC3NFY3KM7:TR?= NYPy[3RpW0GQR1XS
D-247MG MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTsTWM2OD1yLkC3NlA6KM7:TR?= NVvCV29tW0GQR1XS
MMAC-SF NHPtfI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1PtW2lEPTB;MD6wO|I3QCEQvF2= MVvTRW5ITVJ?
CP66-MEL MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYjG[odCUUN3ME2wMlA4PSEQvF2= NFKzXXVUSU6JRWK=
LB771-HNC M1m2UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4jMbWlEPTB;MD6wPFA{PiEQvF2= NGW4W3RUSU6JRWK=
no-10 NULOdlUzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4XjRWlEPTB;MD6wPFkxQSEQvF2= NWXN[2lIW0GQR1XS
A388 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTBwMEmwOlUh|ryP MkH3V2FPT0WU
OPM-2 NXf4Z4IzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX[wTmllUUN3ME2wMlExPDd2IN88US=> NEjDPHVUSU6JRWK=
OVCAR-4 M{HLWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LMW2lEPTB;MD6xNFk{QCEQvF2= M3fMT3NCVkeHUh?=
HOP-62 NGe2WJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHnzN4NKSzVyPUCuNVA6PDlizszN MlfFV2FPT0WU
ML-2 NWTOXGdmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX\XTWRrUUN3ME2wMlEyQDB4IN88US=> MkjwV2FPT0WU
UACC-257 M2flUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LzZ2lEPTB;MD6xNVkzPyEQvF2= NF\yS2NUSU6JRWK=
NEC8 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTBwMUG5PVUh|ryP M2DSWXNCVkeHUh?=
ONS-76 MnPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrGbodFUUN3ME2wMlEzQTN3IN88US=> NETpV3RUSU6JRWK=
KE-37 NIrCbXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnG3TWM2OD1yLkGzNlc5KM7:TR?= M37YTnNCVkeHUh?=
HT-144 NF;me2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{i2Z2lEPTB;MD6xN|g6PSEQvF2= MnzCV2FPT0WU
LB2241-RCC MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGWzcFJKSzVyPUCuNVQzPDdizszN Mn7VV2FPT0WU
TE-5 Mn7XS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2rsNmlEPTB;MD6xOFI4QCEQvF2= M2\BTXNCVkeHUh?=
KINGS-1 NY\hepNNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M12yeWlEPTB;MD6xOFc6KM7:TR?= Mnv6V2FPT0WU
NCI-H69 M13kOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX36VHZLUUN3ME2wMlE2OTRzIN88US=> MoPmV2FPT0WU
CAS-1 NFvXc2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwMUW0PFIh|ryP NED6THFUSU6JRWK=
D-263MG MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlzDTWM2OD1yLkG2NFA3KM7:TR?= M3nNc3NCVkeHUh?=
A253 M4DGUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVrJR|UxRTBwMU[xNlgh|ryP Ml;sV2FPT0WU
PF-382 NWrNPGxzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTBwMU[3NFYh|ryP Mn\iV2FPT0WU
CESS NGHhdIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUTSOohIUUN3ME2wMlE4ODZizszN MmrhV2FPT0WU
MZ2-MEL NWTwVWt[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnKzTWM2OD1yLkG3OVU6KM7:TR?= NHHyfIpUSU6JRWK=
HEL MmTnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVvJR|UxRTBwMUi1NVch|ryP NHPrd4RUSU6JRWK=
D-392MG NEG4bmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3nXpI6UUN3ME2wMlE6OTF3IN88US=> M{X2enNCVkeHUh?=
SK-LMS-1 NWe0[XZOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PQXGlEPTB;MD6xPVMxOyEQvF2= MYHTRW5ITVJ?
GI-ME-N MmrtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\HfmlEPTB;MD6xPVMxPiEQvF2= Mom1V2FPT0WU
LB831-BLC NFzRN4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;GTWM2OD1yLkG5N|Qh|ryP MYHTRW5ITVJ?
DU-4475 NIntTGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nV[WlEPTB;MD6xPVY2QCEQvF2= NFLsVmFUSU6JRWK=
IST-SL1 MmnHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXLJOHZxUUN3ME2wMlIxODl2IN88US=> MoW1V2FPT0WU
GAK M3yzOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVXjXW9SUUN3ME2wMlIxPTN2IN88US=> NHH5PYdUSU6JRWK=
EW-1 NF73XoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTBwMkGwOFch|ryP NVPYS2FzW0GQR1XS
LAMA-84 NGrOc2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTpXHF[UUN3ME2wMlIyQDVzIN88US=> NHHBT3dUSU6JRWK=
SK-UT-1 MnnsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnkcWJ4UUN3ME2wMlIzODR7IN88US=> Mlu3V2FPT0WU
VA-ES-BJ NXLzNpRvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3PXHBKSzVyPUCuNlIzPTdizszN M2XSO3NCVkeHUh?=
ACN NFi1O5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWeyToU2UUN3ME2wMlIzPjN6IN88US=> NVLTXnR2W0GQR1XS
SK-PN-DW M{nYPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1HMTGlEPTB;MD6yN|E6KM7:TR?= MVjTRW5ITVJ?
HD-MY-Z MlrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1S5W2lEPTB;MD6yN|MxOyEQvF2= MYnTRW5ITVJ?
LB373-MEL-D MoThS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnqWmpKSzVyPUCuNlQyQThizszN MkDuV2FPT0WU
COLO-829 M{fUSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXTxdXFKUUN3ME2wMlI1OjV5IN88US=> MljXV2FPT0WU
ES8 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlzGTWM2OD1yLkK0O|Y{KM7:TR?= MlfiV2FPT0WU
RXF393 NVTG[3JvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTBwMkWwNVUh|ryP MX7TRW5ITVJ?
TK10 NXXYNGxwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYnVbYt5UUN3ME2wMlI2PDN3IN88US=> NGTXUnRUSU6JRWK=
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CP67-MEL NH7EZmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfMTWM2OD1yLkK2O|Mh|ryP MVPTRW5ITVJ?
C2BBe1 M3;RTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{LGPGlEPTB;MD6yO|kxPyEQvF2= NVTPTZFlW0GQR1XS
K052 M2Pyc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFPad21KSzVyPUCuNlg6QSEQvF2= NEXZXYtUSU6JRWK=
MOLT-16 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTBwMkm1NlQh|ryP MnrwV2FPT0WU
KNS-81-FD NHLQSmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHWyT3JKSzVyPUCuN|A{OjNizszN Mlr5V2FPT0WU
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LAN-6 MmjKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojMTWM2OD1yLkOxN{DPxE1? MX;TRW5ITVJ?
KLE MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlzpTWM2OD1yLkOxN|A3KM7:TR?= NYnkUXU2W0GQR1XS
NCCIT MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTBwM{G3PFMh|ryP NUTvSVk1W0GQR1XS
HH MkLFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\STWM2OD1yLkOyPFk4KM7:TR?= NWXibZBtW0GQR1XS
TE-8 NEjqVJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7pc|NKSzVyPUCuN|QzPzlizszN NWnqe4F5W0GQR1XS
GDM-1 M17De2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTBwM{WxNFQh|ryP MljMV2FPT0WU
NCI-H747 NVnTUoxqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\wepRPUUN3ME2wMlM4OTB|IN88US=> MVrTRW5ITVJ?
NCI-H1092 NGjtXpBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHriWVBKSzVyPUCuN|g5PDRizszN MV3TRW5ITVJ?
8-MG-BA NFLFNJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX;ybYRDUUN3ME2wMlM6QDN5IN88US=> NETvO21USU6JRWK=
NB17 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4PQ[GlEPTB;MD60Nlk4KM7:TR?= M2LFZnNCVkeHUh?=
LC4-1 NXTJSFMyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYnJR|UxRTBwNEO2NFch|ryP MXzTRW5ITVJ?
TE-1 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1S2WGlEPTB;MD60OVEyQSEQvF2= MoT0V2FPT0WU
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OS-RC-2 M{HtRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M320RmlEPTB;MD60O|k4OiEQvF2= MY\TRW5ITVJ?
A704 NFznZWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWn6PG1VUUN3ME2wMlQ5Pjl{IN88US=> MWPTRW5ITVJ?
BB49-HNC NHGzR49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1mx[GlEPTB;MD60PVA6PiEQvF2= MkTuV2FPT0WU
EVSA-T NXPVZZI5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYjESZdYUUN3ME2wMlQ6QTFzIN88US=> NGfVVlZUSU6JRWK=
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MONO-MAC-6 MlKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYP0XohtUUN3ME2wMlU{PjFzIN88US=> NUP3eZhEW0GQR1XS
BB65-RCC MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmG2TWM2OD1yLkW2PFEyKM7:TR?= MorSV2FPT0WU
NCI-H1882 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{\ZdWlEPTB;MD61PVA{PiEQvF2= M3vQ[3NCVkeHUh?=
TE-9 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTBwNkGwN|Mh|ryP NW\6VINvW0GQR1XS
NCI-H2126 NXy3[2lbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIqxVW5KSzVyPUCuOlI3PjlizszN MoXBV2FPT0WU
SF268 NUDJVmZmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MknwTWM2OD1yLk[1OlQyKM7:TR?= MXzTRW5ITVJ?
SW872 NVfJPIJLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTBwNkW3Nlkh|ryP NWm5fWlwW0GQR1XS
LS-513 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3r2cGlEPTB;MD62Olc2OSEQvF2= NULQeYEyW0GQR1XS
NCI-H1355 NXGwV3k{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXzvNnhpUUN3ME2wMlY5PjF7IN88US=> M1zr[HNCVkeHUh?=
BL-70 NHKyUlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYDJR|UxRTBwNkmzPFgh|ryP NIG1dYZUSU6JRWK=
NCI-SNU-5 MkjUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHjVO2lKSzVyPUCuOlk2PDVizszN NEDhb5RUSU6JRWK=
SNU-C2B MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jRRWlEPTB;MD63NFc{QSEQvF2= MmnWV2FPT0WU
GB-1 M3O2SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV7tT21QUUN3ME2wMlczOTJ2IN88US=> NW\OR3AzW0GQR1XS
CTB-1 NV2xPXl[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NETMXY5KSzVyPUCuO|c6PTVizszN NIDZfJVUSU6JRWK=
Becker Mmf0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\yTWM2OD1yLke5OlIyKM7:TR?= NEHwR4FUSU6JRWK=
KM12 MmL6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;PW5NKSzVyPUCuPFU1PjZizszN NFO0Nm1USU6JRWK=
ES7 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVvpTlZzUUN3ME2wMlg6PjVizszN MUDTRW5ITVJ?
COLO-684 NX;6eoNtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTBwOUC2OVgh|ryP Mnr1V2FPT0WU
HCC2998 NFuwdYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV\JR|UxRTBwOUO4OVQh|ryP NF7QWZJUSU6JRWK=
TE-10 MlGwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmPITWM2OD1yLkm2OFMh|ryP MnvHV2FPT0WU
SF126 NGTmO2RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTBwOUi5O|Eh|ryP NYLUfIsxW0GQR1XS
EKVX M4jJXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TGSGlEPTB;MT6wN|Q1OiEQvF2= M2nhUnNCVkeHUh?=
KARPAS-45 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoDjTWM2OD1zLkC0NFE3KM7:TR?= MofRV2FPT0WU
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L-540 M{nlSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYTpUJdlUUN3ME2xMlEyQDN7IN88US=> NIf3eYRUSU6JRWK=
KURAMOCHI NE[4eGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHRTWM2OD1zLkGyN|c1KM7:TR?= M1jVWXNCVkeHUh?=
LU-65 M{f2XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37xW2lEPTB;MT6xNlc2OyEQvF2= M3POSnNCVkeHUh?=
MFH-ino NWroR|RxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTFwMUe1NFEh|ryP M1\GPXNCVkeHUh?=
NCI-H23 M33Vc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILlUmhKSzVyPUGuNlA1OSEQvF2= M3fWSXNCVkeHUh?=
IA-LM NUH5PZNsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRTFwMkSxNVYh|ryP NEX4TXFUSU6JRWK=
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NCI-H719 NED1bGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2ThUGlEPTB;MT6yO|QyOSEQvF2= MofmV2FPT0WU
SW684 NW\kcFVOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LUTWlEPTB;MT6yPFY2QSEQvF2= MmfOV2FPT0WU
HCE-4 NG\iZ5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH64b3pKSzVyPUGuN|AzOjFizszN NFL2OlRUSU6JRWK=
EW-16 NVq5PI1ZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4eye2lEPTB;MT6zNVM1PyEQvF2= MmnMV2FPT0WU
NCI-H128 MkS0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXSxdWlwUUN3ME2xMlM2QDF2IN88US=> NGWzZXdUSU6JRWK=
HC-1 MmXFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3Pu[WlEPTB;MT6zPFE4KM7:TR?= M2iyW3NCVkeHUh?=
IST-MES1 MnfWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkO3TWM2OD1zLkSwNlA5KM7:TR?= NV7CWJNwW0GQR1XS
Raji NUT5[Go{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2DW[mlEPTB;MT60NVg2KM7:TR?= MXrTRW5ITVJ?
DMS-114 NVfsZopsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTFwNES1N|kh|ryP NV7LOJg3W0GQR1XS
GI-1 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnOWHRKUUN3ME2xMlQ4OTNzIN88US=> M17l[HNCVkeHUh?=
NCI-H2081 MoDqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jSUmlEPTB;MT61OVE6PiEQvF2= MXvTRW5ITVJ?
LC-1F MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NICzb|FKSzVyPUGuOVUyQThizszN M2C5NXNCVkeHUh?=
NCI-H2227 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFTFbVdKSzVyPUGuOlE2PjFizszN M{jTNXNCVkeHUh?=
D-502MG NEfmNJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HxdGlEPTB;MT62O|IyOSEQvF2= NFjJc5BUSU6JRWK=
NCI-H2141 M13Odmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlG5TWM2OD1zLk[3N|E4KM7:TR?= NY\Nem42W0GQR1XS
LS-411N Ml3NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXSwVmw6UUN3ME2xMlY6QDB5IN88US=> MYnTRW5ITVJ?
SU-DHL-1 M{XjTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTFwN{GyPFEh|ryP M2jEdHNCVkeHUh?=
BB30-HNC MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXjJR|UxRTFwN{K2PFUh|ryP Ml;qV2FPT0WU
TE-15 MlHwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnwTWM2OD1zLkmyN|c{KM7:TR?= MUjTRW5ITVJ?
JVM-3 M1uxfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTFwOUO5NFQh|ryP NYXvSJk1W0GQR1XS
IST-SL2 M3m4R2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnoV5hKSzVyPUKuNFEzPTJizszN MoLTV2FPT0WU
EW-18 M{TVV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWT2W3B3UUN3ME2yMlAzOzN5IN88US=> MWDTRW5ITVJ?
DJM-1 MoLlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHv1SlVKSzVyPUKuNFI2PTJizszN M3XxXHNCVkeHUh?=
no-11 NYf0TJMyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4L5OmlEPTB;Mj6wN|ExPCEQvF2= MWnTRW5ITVJ?
QIMR-WIL MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF:1T2JKSzVyPUKuNVY4PjJizszN MVfTRW5ITVJ?
MC-CAR NETqXllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGjrRlBKSzVyPUKuNlI6PSEQvF2= MlG4V2FPT0WU
KM-H2 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnZUHRKSzVyPUKuNlkxPDNizszN NFTYeoFUSU6JRWK=
ECC12 MojLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTJwM{e5OEDPxE1? NVHj[WI{W0GQR1XS
HCE-T NEHMcI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXXZNIxpUUN3ME2yMlQ1QDh|IN88US=> NF7Zc4FUSU6JRWK=
MFM-223 NGPEPYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;YTWM2OD1{LkWwPFcyKM7:TR?= NWLocXlWW0GQR1XS
SW982 MlLVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3vSc2lEPTB;Mj61NVQ5KM7:TR?= MkTnV2FPT0WU
KG-1 NUCxPZpFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHifVlIUUN3ME2yMlg5PzlzIN88US=> NWjmWnZwW0GQR1XS
ES4 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3pPGNDUUN3ME2zMlA3OTFzIN88US=> NFPrbllUSU6JRWK=
SCC-3 NYDSbIJZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1e5XGlEPTB;Mz6xNFg1QCEQvF2= MknSV2FPT0WU
RH-1 Mnq3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MU\JR|UxRTNwM{i3OFgh|ryP MX3TRW5ITVJ?
NCI-H748 NXHkWVFNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTNwNESyOlYh|ryP NEDIPJVUSU6JRWK=
HCC2218 NXvObmMzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NULSOI1{UUN3ME2zMlQ3QTN5IN88US=> MVzTRW5ITVJ?
MEG-01 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTNwNUm2PEDPxE1? MVrTRW5ITVJ?
NB12 NH:2WZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYD1WlAxUUN3ME2zMlU6QDh6IN88US=> NHizNlVUSU6JRWK=
SNB75 MkKzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmPvTWM2OD1|Lk[wNVA{KM7:TR?= NYLUc5NNW0GQR1XS
KMS-12-PE M4fGUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEezXoVKSzVyPUOuOlc4OjNizszN NX7i[2dkW0GQR1XS
SKM-1 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPCTWM2OD1|LkexN|c3KM7:TR?= NGDUSJRUSU6JRWK=
COLO-320-HSR NGDM[3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTNwN{W2N|Qh|ryP NUD3S2lPW0GQR1XS
NKM-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NInCSWFKSzVyPUOuO|c{PzhizszN M13vfHNCVkeHUh?=
TE-6 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnuVpJ3UUN3ME2zMlk1PTZzIN88US=> Mn[xV2FPT0WU
D-336MG Mnj0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3nwSmlEPTB;ND6wNVE3PiEQvF2= M{\ofXNCVkeHUh?=
NCI-H1650 NIfvb5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\3Xpk3UUN3ME20MlE2Pzl5IN88US=> NGLHbVZUSU6JRWK=
ES3 NFT4TXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX7XOHVPUUN3ME20MlMzQDJ2IN88US=> M3PPWXNCVkeHUh?=
YT MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUe2TIJ[UUN3ME20MlM2PDJ2IN88US=> MlPCV2FPT0WU
ES5 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4fzV2lEPTB;ND60NFI2PSEQvF2= Mmi0V2FPT0WU
LB647-SCLC NIfVOYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWXJR|UxRTRwNU[zNFgh|ryP NWji[Gh2W0GQR1XS
HAL-01 M3y4e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1:5eWlEPTB;ND61O|A{PCEQvF2= M2DiXHNCVkeHUh?=
LP-1 M{TVeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVPJR|UxRTRwN{KzO|Eh|ryP M2DCN3NCVkeHUh?=
BC-1 Mkn6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1vNfGlEPTB;NT6wNFQ1PyEQvF2= MYfTRW5ITVJ?
EB-3 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nGZ2lEPTB;NT6wN|A1OSEQvF2= NH7ZUnpUSU6JRWK=
GT3TKB M4X0Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGfYN2pKSzVyPUWuNVc3PjJizszN MoLsV2FPT0WU
NCI-H209 NH7KR2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfLWHg2UUN3ME21MlE6OzV{IN88US=> M3:zPHNCVkeHUh?=
BT-474 NGX6bYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTVwMkOxNFIh|ryP MXzTRW5ITVJ?
RKO M1n2XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX;JR|UxRTVwMkO0NlIh|ryP Ml7QV2FPT0WU
SIMA M2LlXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTVwM{C3OlUh|ryP MWnTRW5ITVJ?
RL M3XnW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{f3TmlEPTB;NT6zO|U1OSEQvF2= MYHTRW5ITVJ?
GCIY MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvGTWM2OD13LkS3NlM3KM7:TR?= MV3TRW5ITVJ?
Calu-6 M3rMV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVvNdmhsUUN3ME21MlYzOiEQvF2= NIftemZUSU6JRWK=
ALL-PO NVq0PWJ[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fnfWlEPTB;NT62N|c6PSEQvF2= MWfTRW5ITVJ?
ARH-77 M4nLN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDsTWM2OD13Lk[3NFg4KM7:TR?= MYjTRW5ITVJ?
A4-Fuk NFL0e2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3rG[WlEPTB;Nj6wPFEyQCEQvF2= M4jwR3NCVkeHUh?=
NCI-H1581 NX72U|R5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4nLd2lEPTB;Nj6yN|g1QSEQvF2= M{e0cXNCVkeHUh?=
HUTU-80 NV3IXGhmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV\JR|UxRTZwM{[4PVch|ryP MknVV2FPT0WU
TGW NGH0N21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NInEc4NKSzVyPU[uOFU2QTNizszN NWWzPFBCW0GQR1XS
SK-N-FI NUf6co1ZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjKcWNKSzVyPU[uOFU5PTRizszN NVfyTo5SW0GQR1XS
U-266 MnznS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGTSXIFKSzVyPU[uOVE6OjZizszN NHX1b3RUSU6JRWK=
EM-2 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmfxTWM2OD14Lk[3NFk6KM7:TR?= MmjRV2FPT0WU
NMC-G1 NEnWWIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlHzTWM2OD14LkexPFk2KM7:TR?= M1zvTXNCVkeHUh?=
KASUMI-1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGjtS3hKSzVyPU[uPFQ4QDdizszN NIX3[|ZUSU6JRWK=
NALM-6 M3ztR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{Lt[GlEPTB;Nj64Olc2PCEQvF2= MkG5V2FPT0WU
OCI-AML2 NI\xXHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTdwMECzNlYh|ryP M3[1RXNCVkeHUh?=
SHP-77 MofLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrGUo9KSzVyPUeuNlI1OyEQvF2= MmDlV2FPT0WU
NOMO-1 NIX2XnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWDJR|UxRTdwMkSyOVQh|ryP Mkm4V2FPT0WU
SK-N-DZ NX;ZTlZ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVvlUlBEUUN3ME23MlcyODh7IN88US=> NH\IToJUSU6JRWK=
LB1047-RCC NUTkWZNoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NELIUpdKSzVyPUeuO|IzOzFizszN MXrTRW5ITVJ?
MZ1-PC NGDpO4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTdwOE[1OVgh|ryP MXLTRW5ITVJ?
NB10 NUm4SnZqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoXnTWM2OD15Lkm5OVU3KM7:TR?= MVvTRW5ITVJ?
RL95-2 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzKOpZKSzVyPUiuNVA5PDJizszN NWjKc21HW0GQR1XS
OMC-1 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjjeJpKSzVyPUiuOVIyQTFizszN NFfhe3dUSU6JRWK=
D-283MED M3Lpemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEPMbZlKSzVyPUiuPVE4OTlizszN NFjlUlhUSU6JRWK=
MC116 M3n3e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRThwOUe5OEDPxE1? NWjadlNTW0GQR1XS
SJSA-1 MmHKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVXJR|UxRTlwMEmwPVEh|ryP M3nmXHNCVkeHUh?=
JiyoyeP-2003 MmXjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnBd5pKSzVyPUmuNlk{OTdizszN NE\6[45USU6JRWK=
IST-MEL1 MkPzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3nv[2lEPTB;OT63OFE6QCEQvF2= M13od3NCVkeHUh?=
CTV-1 NVPMbXhmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHz4PFRKSzVyPUGwMlA6PzlizszN Mn:4V2FPT0WU
NH-12 M1zGUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTFyLkK0N|Mh|ryP NVnpU4h1W0GQR1XS
CA46 M{L6cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvGepBKSzVyPUGwMlM3OSEQvF2= NXW2coxGW0GQR1XS
NCI-SNU-1 Mn\GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIe2TIpKSzVyPUGwMlQ6PjlizszN NEnHS2ZUSU6JRWK=
SCLC-21H NHPwboZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jJUGlEPTB;MUCuOlU6PiEQvF2= NUX2blY2W0GQR1XS
EC-GI-10 M2fTXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTFyLkewN|Eh|ryP M1zUcXNCVkeHUh?=
SR M1[y[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVHxbXFoUUN3ME2xNU4xOTh3IN88US=> MnTNV2FPT0WU
NCI-H1648 MkjRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFnVPHJKSzVyPUGxMlA6PjVizszN M4f3[3NCVkeHUh?=
TGBC1TKB M1rSSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH3oeXNKSzVyPUGxMlQyODJizszN M4SwSHNCVkeHUh?=
EW-11 Mm\xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY\JR|UxRTFzLkWxPFYh|ryP M370UnNCVkeHUh?=
SK-MM-2 MlP2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnwO2pKSzVyPUGxMlgxPjFizszN M{j0bnNCVkeHUh?=
NCI-H524 NIHwcpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{XIUWlEPTB;MUGuPVgzOiEQvF2= MnjZV2FPT0WU
NOS-1 M3L6fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH7JZYFKSzVyPUGyMlA{PDVizszN NFW5eohUSU6JRWK=
AM-38 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXL2UYVOUUN3ME2xNk42PjN|IN88US=> NYXHXHZLW0GQR1XS
A498 M2nX[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfZ[4M2UUN3ME2xNk44ODZ7IN88US=> MlXHV2FPT0WU
KARPAS-422 MnTJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYPBfJJKUUN3ME2xNk44PDl4IN88US=> M1XxUXNCVkeHUh?=
LU-139 NFjBXVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M33nR2lEPTB;MUKuPVAzPiEQvF2= Mlf6V2FPT0WU
COR-L88 Mm\3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\O[mFXUUN3ME2xNk46Ozh{IN88US=> MWrTRW5ITVJ?
K5 NWG0XGhXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYHNcpV1UUN3ME2xNk46PDZ{IN88US=> MonqV2FPT0WU
NB13 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIrTTHpKSzVyPUGyMlk4QDNizszN M3;mO3NCVkeHUh?=
MRK-nu-1 NV\keFEyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV;kboR7UUN3ME2xN{4yQTVizszN MWHTRW5ITVJ?
MHH-NB-11 M4rxVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2n4SGlEPTB;MUOuNlkxOiEQvF2= NFPaRXhUSU6JRWK=
KU812 M3;GVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPLeXdKSzVyPUGzMlYyOjRizszN MWfTRW5ITVJ?
TE-12 MoDZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHflUI5KSzVyPUGzMlY6QTRizszN NX35XJFLW0GQR1XS
NCI-N87 NFjLN4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1za[WlEPTB;MUOuO|M3KM7:TR?= NVTTVmVVW0GQR1XS
EB2 MoDMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTjTWM2OD1zMz64OVA2KM7:TR?= MVrTRW5ITVJ?
DB M4DQZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVTleVFkUUN3ME2xN{46QDh3IN88US=> NILsSYJUSU6JRWK=
697 M3vWNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIewWGxKSzVyPUG0MlQ2OTFizszN MkPkV2FPT0WU
MSTO-211H NH3kPI1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVTRS21sUUN3ME2xOE44PDR6IN88US=> MYPTRW5ITVJ?
JVM-2 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmDtTWM2OD1zND63O|M2KM7:TR?= NFrl[FJUSU6JRWK=
COLO-824 MmHzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrqVlVKSzVyPUG0Mlc6QTRizszN NEjhU|hUSU6JRWK=
BC-3 NFvTXJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXLYNY5QUUN3ME2xOU4{QThizszN MXjTRW5ITVJ?
BOKU MmDXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M37JcWlEPTB;MUWuPVYxQCEQvF2= M4K3NXNCVkeHUh?=
GOTO MnrtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{nCZmlEPTB;MU[uPVYyPyEQvF2= MVfTRW5ITVJ?
HCC2157 MnvJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;NNJZKSzVyPUG3MlQ4PTVizszN MkPTV2FPT0WU
LS-1034 M2LWS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37hN2lEPTB;MUeuOlgyQCEQvF2= M4\1WXNCVkeHUh?=
CAL-148 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTF5Lkm3PVYh|ryP NHTNfIFUSU6JRWK=
MOLT-4 NUO0cHZJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoT4TWM2OD1zOD64NlA5KM7:TR?= M3jXPXNCVkeHUh?=
Daudi MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NU[2VZZ7UUN3ME2xPE46OjNzIN88US=> MWTTRW5ITVJ?
J-RT3-T3-5 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoDKTWM2OD1zOT60NFY3KM7:TR?= NHjyfmxUSU6JRWK=
KMOE-2 NUTvb|gyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjNfZYyUUN3ME2xPU43PDh{IN88US=> NHHWXXBUSU6JRWK=
HL-60 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3tTWM2OD1{MD6xPVY2KM7:TR?= MoTZV2FPT0WU
P31-FUJ Mn;3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTJyLkS3OVMh|ryP MVjTRW5ITVJ?
IM-9 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTJyLk[yNlQh|ryP MVXTRW5ITVJ?
HDLM-2 NYHTOllxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYrJR|UxRTJyLki4NlEh|ryP M{jvWnNCVkeHUh?=
NCI-H1304 NHzXXVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nxV2lEPTB;MkGuNFMyOSEQvF2= MkfYV2FPT0WU
NCI-H345 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nrWGlEPTB;MkGuNFY1OyEQvF2= NYfPdJBXW0GQR1XS
RPMI-6666 NWLxcGF2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoH0TWM2OD1{MT6zOlAzKM7:TR?= M4\hbnNCVkeHUh?=
GR-ST NU\IXmp6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1\oXWlEPTB;MkGuOFE4KM7:TR?= NYXEWnBqW0GQR1XS
CHP-126 NV7lVpBET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfxPZRKSzVyPUKxMlYyQDFizszN M1XObHNCVkeHUh?=
EHEB MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTJzLk[3N|Eh|ryP MnLCV2FPT0WU
CPC-N NF6zclFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUT2c2JCUUN3ME2yOE4xOjBzIN88US=> NXXtfZJLW0GQR1XS
NB1 NVX2W4NFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYDCNXRrUUN3ME2yOE43QTN7IN88US=> M1zZeHNCVkeHUh?=
LS-123 MmDWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYjJR|UxRTJ2LkmwNVIh|ryP NF\Fb4dUSU6JRWK=
ST486 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{C4OWlEPTB;MkWuNVEyOyEQvF2= MWHTRW5ITVJ?
NCI-H1963 M{HX[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXfJR|UxRTJ4LkC2NlMh|ryP NH\yZ4NUSU6JRWK=
U-87-MG NEmxWmdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzCdY9YUUN3ME2yOk44PjR2IN88US=> M3XzU3NCVkeHUh?=
COR-L279 M1zy[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjOOGNKSzVyPUK2Mlc6OjJizszN MYjTRW5ITVJ?
LU-165 NVz1eIhuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4m0OWlEPTB;MkiuNFg3OSEQvF2= NUK2T3V6W0GQR1XS
COLO-800 M{PnVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUHrd49nUUN3ME2yPE4zQTV4IN88US=> NI\wSXdUSU6JRWK=
ETK-1 NHflco9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jvSmlEPTB;MkiuN|Q1PiEQvF2= NUe2VWJ4W0GQR1XS
LNCaP-Clone-FGC MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX\1cGFkUUN3ME2yPU46OjhzIN88US=> MX\TRW5ITVJ?
SIG-M5 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3lcItyUUN3ME2zNE44QTV{IN88US=> Mof2V2FPT0WU
NB6 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLPOWVKSzVyPUOwMlk2ODNizszN MoD2V2FPT0WU
NCI-H2107 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUfqSIRTUUN3ME2zNU4zOzN6IN88US=> M{e5e3NCVkeHUh?=
SNU-C1 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGDtNHVKSzVyPUOxMlMyOjZizszN MXPTRW5ITVJ?
JAR M3HycGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M33hNGlEPTB;M{GuN|c6QSEQvF2= NFHV[ZdUSU6JRWK=
L-363 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M13YT2lEPTB;M{KuNlE1PCEQvF2= NUPPW4xzW0GQR1XS
EW-24 MljWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlvzTWM2OD1|Mj6zOFc1KM7:TR?= MX\TRW5ITVJ?
NB69 NUjxPId5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2CxXmlEPTB;M{OuOlQ2PCEQvF2= NX\ER4V[W0GQR1XS
EW-13 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnVXFJKUUN3ME2zN{45QTZ7IN88US=> MoTsV2FPT0WU
Ramos-2G6-4C10 NGjue5lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1f2fmlEPTB;M{SuNlk6OyEQvF2= Ml;sV2FPT0WU
TE-11 MlnzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWXJR|UxRTN2LkS4NlIh|ryP M{DQO3NCVkeHUh?=
L-428 MnrES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnvRTWM2OD1|ND63OVM3KM7:TR?= M2PRfXNCVkeHUh?=
KP-N-YN M2PU[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkDtTWM2OD1|ND65NFU4KM7:TR?= Mn:yV2FPT0WU
CGTH-W-1 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVXJR|UxRTN4LkmwOFgh|ryP NFXHbJlUSU6JRWK=
K-562 NUflXZljT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRTN5LkC4OlQh|ryP MVfTRW5ITVJ?
NCI-H1299 NY\qcWRET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHMTWM2OD1|OD6xOlA{KM7:TR?= MYXTRW5ITVJ?
RCC10RGB NILKSXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M33Ze2lEPTB;M{iuNlA5OyEQvF2= NGe5N|BUSU6JRWK=
NCI-SNU-16 M1;3U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXizXWhPUUN3ME2zPE42PjV|IN88US=> MVLTRW5ITVJ?
LC-2-ad NGLoV4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVHoZ5ZuUUN3ME2zPU41OzN5IN88US=> M{X6dnNCVkeHUh?=
MHH-PREB-1 NYLBNoVuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXK0Z2VRUUN3ME2zPU44Ozh6IN88US=> MVzTRW5ITVJ?
NCI-H64 MlrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFjuS2xKSzVyPUSwMlA6PDhizszN NWTufI1KW0GQR1XS
LB996-RCC Ml;3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlSzTWM2OD12MD64O|E3KM7:TR?= NXr0OIsyW0GQR1XS
DEL MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn:xTWM2OD12MT60OFA2KM7:TR?= MlPxV2FPT0WU
MLMA NVrQWHp5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYjuW3A3UUN3ME20NU44PTl3IN88US=> MlnxV2FPT0WU
SBC-1 M2GxR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIf4XJBKSzVyPUSyMlE5ODZizszN MUjTRW5ITVJ?
MPP-89 NGjGe|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWDwb41tUUN3ME20Nk42QDd3IN88US=> MWXTRW5ITVJ?
MV-4-11 NYf3d5ozT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUjqfFhtUUN3ME20Nk46ODZ5IN88US=> Mn;qV2FPT0WU
EoL-1- NYj3UoR5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrFdXM6UUN3ME20OE4yPTZ6IN88US=> M4KxcnNCVkeHUh?=
CW-2 MoS1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlvzTWM2OD12ND64N|QzKM7:TR?= M{nkN3NCVkeHUh?=
HT MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTR3LkewNFch|ryP NW\RUYlQW0GQR1XS
SW954 NECwOmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjnTWM2OD12Nz60NVI5KM7:TR?= MXjTRW5ITVJ?
A3-KAW NYLUVIZ7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmj5TWM2OD12OT64NFYyKM7:TR?= NEjZemFUSU6JRWK=
TC-YIK M4O4[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLMbIRKSzVyPUWwMlA{PjNizszN NYjUPHZFW0GQR1XS
SW962 NFvwN45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXnJR|UxRTV2LkizOVch|ryP NVn6emZDW0GQR1XS
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NCI-H1395 NG\SN5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUnjXlNMUUN3ME21PE45OTd{IN88US=> NXHETnM1W0GQR1XS
RPMI-8402 MnzFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTV6Lkm1NlYh|ryP M{fYUnNCVkeHUh?=
SCH NF7jcm9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUDRSYZJUUN3ME22NE46PjN6IN88US=> M2HwOnNCVkeHUh?=
NCI-H2196 MmHPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzkUIdKSzVyPU[xMlI{OSEQvF2= Mn;uV2FPT0WU
LOXIMVI MoTOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;UdoZKSzVyPU[xMlgzPjZizszN NUHPb|drW0GQR1XS
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NCI-H1522 NIH0fVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DzSGlEPTB;NkmuNFA1PyEQvF2= NFKzOmdUSU6JRWK=
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NCI-H82 MnHyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTdzLkm1NFch|ryP MnnwV2FPT0WU
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NCI-H1436 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUTJR|UxRTd{Lke0OVYh|ryP M1;ZdHNCVkeHUh?=
ATN-1 NHjlbJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlmyTWM2OD15ND61NFUh|ryP M4HJPHNCVkeHUh?=
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HCC1599 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTd2Lki3N|Ih|ryP MYDTRW5ITVJ?
NCI-H1155 NYf0eGJuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{jjSmlEPTB;N{SuPVM3PyEQvF2= M1rGZ3NCVkeHUh?=
DOHH-2 M2rkS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXWTVlKSzVyPUe0Mlk2OTRizszN MYTTRW5ITVJ?
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NCI-H322M MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUPJR|UxRTd6LkO3NFkh|ryP NXfXWnlyW0GQR1XS
NCI-H526 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2jF[2lEPTB;N{iuOVg4PyEQvF2= MWfTRW5ITVJ?
NCI-H2171 NEnxSINIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NG\FVYJKSzVyPUe5MlQyOzZizszN NEDETYNUSU6JRWK=
COLO-668 M1TYVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYTndpJYUUN3ME24NU42QDh2IN88US=> NGLxUnZUSU6JRWK=
RS4-11 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUKzfWd1UUN3ME24Nk4zPTB3IN88US=> NVv5TXczW0GQR1XS
NCI-H716 M1\iSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;kTWM2OD16Mj65NFc2KM7:TR?= M4\qZXNCVkeHUh?=
LU-134-A MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlK4TWM2OD16Mz6xN|UyKM7:TR?= NHqwWndUSU6JRWK=
RPMI-8226 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTh2LkKxNFch|ryP MkDmV2FPT0WU
KY821 MkPhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX3JR|UxRTlzLk[1OVEh|ryP MYDTRW5ITVJ?
ECC4 M2\5bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlzlTWM2OD17Mz64NlY6KM7:TR?= NGPZdWlUSU6JRWK=
EW-3 M2fUSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTl2LkmwPFEh|ryP NIrQWmFUSU6JRWK=
NB7 NYXtVIZDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnYO4puUUN3ME25OU44Pzh4IN88US=> NYfUOlNYW0GQR1XS
NCI-H720 MlO3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYPJXlF5UUN3ME25PE41ODZzIN88US=> Mn3aV2FPT0WU
NCI-H446 Ml3vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\mPJdQUUN3ME25PU44PTh6IN88US=> NFi1XJZUSU6JRWK=
NCI-H889 M1Pp[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFHUSnVKSzVyPUGwOE4zPDJizszN NWnVPJhoW0GQR1XS
EW-22 NEfSblZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHP6OWhKSzVyPUGwOk4yQSEQvF2= M2fIVnNCVkeHUh?=
BV-173 NHWwN|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVXJR|UxRTFyOD63Nlgh|ryP MX3TRW5ITVJ?
WSU-NHL NYWyeIhTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFewdZZKSzVyPUGwPU43PzFizszN NHzTTWtUSU6JRWK=
MN-60 NH;yfYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnXd4RDUUN3ME2xNFkvPjlizszN NWTK[JBoW0GQR1XS
DG-75 NVLqT3RlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYXPcmhEUUN3ME2xNVMvOzV{IN88US=> NES4[YJUSU6JRWK=
DMS-79 NGLmZYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zKUGlEPTB;MUG3MlM5OiEQvF2= MkHoV2FPT0WU
SK-MEL-1 NYnVN3FLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mny5TWM2OD1zMUiuNFA6KM7:TR?= MVXTRW5ITVJ?
DMS-153 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXXTWM2OD1zMkGuO|Q2KM7:TR?= MXLTRW5ITVJ?
NCI-H510A MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXjIfWFqUUN3ME2xNlcvOzJizszN MUjTRW5ITVJ?
BE-13 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2ixVGlEPTB;MUO0MlA1PCEQvF2= MWfTRW5ITVJ?
KP-N-YS MkPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M33I[2lEPTB;MUO5Mlc{PiEQvF2= NFO4UXRUSU6JRWK=
SUP-T1 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkmwTWM2OD1zNEOuO|A5KM7:TR?= MnmzV2FPT0WU
EW-12 M3vDO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWfodoxsUUN3ME2xOFQvPjl7IN88US=> NF;UT3NUSU6JRWK=
NB14 NXfqeJZLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{XGWGlEPTB;MUS3MlA5OiEQvF2= M{jkcXNCVkeHUh?=
MDA-MB-134-VI MoSyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnQZlBKSzVyPUG0PE4zPjhizszN MX\TRW5ITVJ?
NCI-H1770 NHfGU|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUTtV|JiUUN3ME2xOVYvOjd7IN88US=> M2LKUHNCVkeHUh?=
TUR M2qyU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFPGdVdKSzVyPUG2O{45PyEQvF2= NE\URVdUSU6JRWK=
NCI-H1417 NFS0RplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4DDO2lEPTB;MUiwMlM{OSEQvF2= MYrTRW5ITVJ?
IMR-5 M{HUe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvZRnpKSzVyPUG4NU42PzFizszN NYGyPWZyW0GQR1XS
NCI-H226 Mmm5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\xTWM2OD1zOEiuPFY3KM7:TR?= NILFc2VUSU6JRWK=
NCI-H187 NX7TOIt7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYfEZVVlUUN3ME2xPVAvODZ2IN88US=> MnmwV2FPT0WU
SF539 MonzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1rCe2lEPTB;MUmyMlczQCEQvF2= M3fsZ3NCVkeHUh?=
TALL-1 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4PJT2lEPTB;MUm4MlMxPCEQvF2= NXvtOGM4W0GQR1XS
TE-441-T M4r0Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3rNW2lEPTB;MUm5Mlc{QSEQvF2= M3PWT3NCVkeHUh?=
REH NH3KZWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mmf0TWM2OD1{M{[uOlI3KM7:TR?= NWLmdI5NW0GQR1XS
MS-1 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVrJR|UxRTJ|OT6xNlEh|ryP NHTIV|JUSU6JRWK=
THP-1 NHXHdW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUnJR|UxRTJ4ND63N|gh|ryP Mn7ZV2FPT0WU
NCI-H1838 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUfTRmI6UUN3ME2yO|EvPDV4IN88US=> MkTCV2FPT0WU
P30-OHK MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nwTWlEPTB;MkizMlg1PyEQvF2= NE\5[mlUSU6JRWK=
C8166 NWXidoVQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFSzfpBKSzVyPUO0OU4{OzhizszN NIn1Z4tUSU6JRWK=

多くの細胞株試験データを見る場合、クリックしてください

体内試験 Administration of MG-132 effectively rescues the expression levels and plasma membrane localization of dystrophin, β-dystroglycan, α-bdystroglycan, and α-sarcoglycan in skeletal muscle fibers from mdx mice, reduces muscle membrane damage, and ameliorates the histopathological signs of muscular dystrophy. [7] MG-132 treatment significantly reduces immobilization-induced skeletal muscle atrophy in mice, by downregulating the muscle-specific ubiquitin ligases atrogin-1/MAFbx and MuRF-1 mRNA. [8]

お薦めの試験操作(参考用のみ)

キナーゼ試験:

[1]

+ 展開

Measurement of inhibitory activities of MG-132 against 20S proteasome:

The reaction mixture for the 20S proteasome inhibitory assay contains 0.1 M Tris-acetate, pH 7.0, 20S proteasome, MG-132, and 25 μM substrate dissolved in dimethyl sulfoxide in a final volume of 1 mL. After incuba tion at 37 °C for 15 minutes, the reaction is stopped by the addition of 0.1 mL of 10% SDS and 0.9 mL of 0.1M Tris acetate, pH 9.0. The fluorescence of the reaction products is measured. To determine the IC50 against 20S proteasome, various concentrations of MG-132 are included in the assay mixture.
細胞試験:

[3]

+ 展開
  • 細胞株: KIM-2, HC11, and ES
  • 濃度: Dissolved in DMSO, final concentrations ~25 μM
  • 反応時間: 24, and 48 hours
  • 実験の流れ:

    Cells are exposed to various concentrations of MG-132 for 24, and 48 hours. Supernatant and monolayer cells are harvested by centrifugation and fixed in 70% ethanol in PBS for staining with acridine orange. Equal volumes of cells and acridine orange (5 mg/mL in PBS) are mixed on a microscope slide and examined by fluorescence microscopy. For annexin V analysis, cells are harvested by centrifugation and stained with annexin V and propidium iodide. For cell cycle analysis, cells are rehydrated in PBS at room temperature for 10 minutes, followed by staining with propidium iodide (5 mg/mL). All samples are analyzed using a Coulter Epics XL flow cytometer.


    (参考用のみ)
動物試験:

[7]

+ 展開
  • 動物モデル: Male mdx (C57BL/10ScSn DMD mdx) mice
  • 製剤: Dissolved in DMSO, and diluted in PBS
  • 投薬量: ~10 μg/kg/day
  • 投与方法: Injection
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 90 mg/mL (189.22 mM)
Ethanol 25 mg/mL (52.56 mM)
Water Insoluble
体内 左から右までの手順で、溶剤を製品に加えることです:
4% DMSO+30% PEG 300+20% propylene glycol+ddH2O
いい結果が出るために、混じった後、直ちに使うと推めます。
2mg/mL

* 溶解度検測はSelleck技術部門によって行いますので、文献より提供された溶解度と差異がある可能性がありますが、生産工芸と不同ロット(lot)で起きる正常な現象ですから、ご安心ください。

化学情報

分子量 475.62
化学式

C26H41N3O5

CAS No. 133407-82-6
保管
in solvent
別名 N/A

便利ツール

モル濃度計算器

モル濃度計算器

解決のために必要とされるマス、ボリュームまたは濃度を計算してください。

マス (g) = 濃度 (mol/L) x ボリューム (L) x 分子量 (g/mol)

モル濃度計算器方程式

  • マス
    濃度
    ボリューム
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備することを要求される希釈剤を計算してください. セレック希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 輸入 輸出 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

マス 濃度 ボリューム 分子量

技術サポート

ストックの作り方、阻害剤の保管する方法、細胞実験や動物実験に注意すべきな点を全部含めており、製品を取扱う時よくあった質問に対して取扱説明書でお答えいたします。

Handling Instructions

他の質問がある場合は、お気軽くお問合せください。

  • * 必須

よくある質問(FAQ)

  • 問題1:

    I want to know whether it contains EDTA or other chelating agent in this product(S2619)?

  • 回答:

    Our S2619 MG-132 doesn't contain EDTA or other chelating agent.

Proteasomeシグナル伝達経路

Proteasome Inhibitors with Unique Features

相関Proteasome製品

Tags: MG-132を買う | MG-132 ic50 | MG-132供給者 | MG-132を購入する | MG-132費用 | MG-132生産者 | オーダーMG-132 | MG-132化学構造 | MG-132分子量 | MG-132代理店
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細胞株 試験類型 濃度 培養時間 溶剤類型 活性叙述 PMID