MG-132

製品コードS2619

MG-132化学構造

分子量(MW):475.62

MG-132は一種のプロテアソーム阻害剤で、無細胞試験でIC50値が100nMですが、カルパイン(calpain)も抑制して、このIC50値が1.2μMになります。

サイズ 価格 在庫  
JPY 14398.80 あり
JPY 7199.40 あり
JPY 24477.96 あり
JPY 67674.36 あり

文献中の引用(47)

カスタマーフィードバック(10)

  • MDA-MB-231 cells were treated with 10 uM MG132 and incubated under normoxia or hypoxia for 4 h. Endogenous interaction between LATS2 and SIAH2 was analysed by immunoprecipitation.

    Nat Cell Biol 2015 17(1), 95-103. MG-132 purchased from Selleck.

    HeLa cells were transfected with control mimic, RMND5A siRNA or miR-138 mimic. After transfection for 36 h, cells were treated with proteasome inhibitor MG132 (20 uM) or Dimethyl sulfoxide (DMSO) for 8 h. Endogenous Exportin-5 protein and RMND5A protein expression was measured by western blotting.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

  • HeLa cells were transfected with negative control mimic, miR-138 mimic or RMND5A siRNA. After transfection for 36 h, cells were treated with MG132 (20 uM) or DMSO for 8 h. RMND5A and Exportin-5 protein expression were analyzed by immunocytochemistry. Nuclei were counterstained with DAPI.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

     

    TFEB induced autophagy dependent ATZ clearance in vitro. MEF transiently co-transfected with either ATZ plus GFP expressing plasmids or ATZ plus TFEB expressing plasmids were incubated with proteasome inhibitor MG132 or with DMSO for 6 h. Upon MG132 treatment, steady state levels of 52 kDa ATZ band increased in both cells transfected with ATZ plus GFP and with ATZ plus TFEB expressing plasmids. Quantification of band intensities showed a 48% reduction of ATZ in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP, in the absence of the proteasome inhibitor. In MG132 treated cells, a 61% decrease of ATZ was detected in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP.

    EMBO Mol Med 2013 5, 397-412. MG-132 purchased from Selleck.

  • JAK1 expression was analyzed in A375 cells expressing scrambled shRNA or shRNF125 (#2) and treated with MG132 (5 uM, 10 hr), and in Lu1205 cells expressing WT RNF125 and treated with MG132.

    Cell Rep 2015 11(9), 1458-73. MG-132 purchased from Selleck.

    LRB1 and LRB2 regulate phyB protein levels. PhyB protein levels in crude extracts from the wild type (WT) and the indicated mutant backgrounds were assayed by immunoblot analysis with anti-phyB monoclonal antibodies. Anti-PBA1 and anti-histone H3 antibodies were used to confirm equal protein loading. Rc-induced loss of phyB in the wild type is inhibited by 100 uM MG132.

    Plant Physiol 2012 60(1), 118-34. MG-132 purchased from Selleck.

  • Representative images for γ-H2AX-stained cells treated with 100 uM FA for 3 h without or with MG132. Fluorescence was measured in at least 50 nuclei in each of three experiments.

    Toxicol Appl Pharmacol 2015 286(2), 135-41. MG-132 purchased from Selleck.

    GSK-3β phosphorylation at Ser9 is enhanced in NOK-overexpressed stable cell lines. The proteasome inhibitor, MG132, was added in medium of HeLa-HA and HeLa-NOK-HA cells for 12 h and then the p-GSK-3b(Ser9) was assayed by western blotting.

    FEBS Lett 2012 586, 3787–3792. MG-132 purchased from Selleck.

  • Nek2A impedes SuFu ubiquitination. HEK293T cells transfected with Nek2A-Myc and Flag-SuFu for 48 h were treated with MG-132 to enrich ubiquitinated proteins, and subsequently subjected to co-immunoprecipitation assay. Precipitated proteins were probed using anti-Ub antibody.

    Int J Oncol, 2017, 50(2):373-380. MG-132 purchased from Selleck.

    Truncated mouse Period2 (Per2) protein was expressed in NIH3T3 cells, treated by cycloheximide with or without MG132 for 1-4 hours.Per2 was reported to be degraded by the proteasome proteolysis. By adding MG132 (25 μM), a proteasome inhibitor, the degradation of Per2 was dramatically decreased within 4 hours treatment (shown by western blot).

    2012 Dr. Edison DUKE-NUS Graduate Medical School Singapore.. MG-132 purchased from Selleck.

質量管理及び製品安全説明書

Proteasome阻害剤の選択性比較

生物活性

製品説明 MG-132は一種のプロテアソーム阻害剤で、無細胞試験でIC50値が100nMですが、カルパイン(calpain)も抑制して、このIC50値が1.2μMになります。
ターゲット
Proteasome [1]
(Cell-free assay)
100 nM
体外試験

MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM. MG-132 also inhibits calpain with IC50 of 1.2 μM. MG-132 induces neurite outgrowth in PC12 cells at an optimal concentration of 20 nM, displaying 500 times more potency than ZLLal. [1] MG-132 (10 μM) potently inhibits TNF-α-induced NF-κB activation, interleukin-8 (IL-8) gene transcription, and IL-8 protein release in A549 cells by inhibition of proteasome-mediated IκBα degradation. [2] MG-132 treatment potently induces p53-dependent apoptosis in KIM-2 cells by 26S proteasome inhibition. [3] Unlike BzLLLCOCHO or PS-341, MG-132 treatment results in weak inhibition of the chymotrypsinlike (CT-L) and peptidylglutamyl peptide hydrolysing (PGPH) activities of the 26S proteasome, whereas multiple myeloma cells (U266 and OPM-2) are more sensitive to induction of apoptosis by MG-132 than BzLLLCOCHO. [4] MG-132 (1 μM) sensitizes TRAIL-resistant prostate cancer cells by activating the AP-1 family members c-Fos and c-Jun, which, in turn, repress the antiapoptotic molecule c-FLIP(L). [5] MG-132 significantly enhances the ability of inositol hexakisphosphate (IP6) to reduce cellular metabolic activity in both PC3 and DU145 androgen-independent prostate cancer (AIPCa) cell lines. [6]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
LPS-stimulated RAW264.7 cells Mn3iSpVv[3Srb36gRZN{[Xl? NXK2WZR4OjVizszN MmrOSG1UVw>? NIHrbFNKdmirYnn0d{BvcXS{aXOgc5hq\GVicILv[JVkfGmxbjD3bZRpKEmFNUCgc4YhOC5zIN88US=> NX;sNpZSOjR4OUe0PVY>
HL-60 M17RW2N6fG:2b4jpZ{BCe3OjeR?= MUK0NEDPxE1? NFL4clE1QCCq NVv6O5U4TE2VTx?= NIfZbIJKSzVyPEGwJO69VQ>? NFv5XYszPDZ7N{S5Oi=>
SMMC-7721 NVTRW4FiS3m2b4TvfIlkKEG|c3H5 MXm0NEDPxE1? Ml;SOFghcA>? Mk\USG1UVw>? M3e2cGlEPTB;Nz6xJO69VQ>? NInn[WwzPDZ7N{S5Oi=>
A-549 NX7JWWtGS3m2b4TvfIlkKEG|c3H5 MYG0NEDPxE1? NEnPVGQ1QCCq M1TBW2ROW09? M2PKfWlEPTB:MUCg{txO NVHFZ2ZWOjR4OUe0PVY>
MCF-7 MWHDfZRwfG:6aXOgRZN{[Xl? M2LLSVQxKM7:TR?= MXy0PEBp Mne2SG1UVw>? M1PBXWlEPTB;Nz6zJO69VQ>? NV;pVIFSOjR4OUe0PVY>
SW-480 MVXDfZRwfG:6aXOgRZN{[Xl? MkTwOFAh|ryP NIXBOZM1QCCq NFX0Zo9FVVOR MWnJR|UxRTRizszN NEftfZUzPDZ7N{S5Oi=>
NCI-H929 NFi2b4pEgXSxdH;4bYMhSXO|YYm= MmLwNUDPxE1? MnrnO|IhcA>? M4L4eGROW09? NWfmd2JxUUN3ME2wMlE4KM7:TR?= M1nKWFI1PjJ3MEi4
293T NILwOZpEgXSxdH;4bYMhSXO|YYm= NInXbHgyOCEQvF2= NX7EXpM6PzJiaB?= NEfNU3BFVVOR NHjEem9KSzVyPEKg{txO MWWyOFYzPTB6OB?=
293T M1H6TWZ2dmO2aX;uJGF{e2G7 M3\DPFExKM7:TR?= NV\pVVRlOjRiaB?= NVfhTYM4TE2VTx?= MlTaUY9l\XKjdHXsfUBqdmS3Y3XzJIhm[XRvc3jvZ4shKA>? NWDN[nJtOjR4MkWwPFg>
HeLa MmK0T4lv[XOnIFHzd4F6 M1LnTlExKM7:TR?= NHfTPYQyKGh? NEXwe21FVVOR MXLJcoR2[2W|IGDBVnAh[2ynYY\h[4Uh[nliaX7obYJqfGmwZzDwdo9{\WG|b33lJIFkfGm4aYT5 M1;6WlI1OzJzOEOz
MDA-MB-231 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnFPJcyKM7:TR?= M4roclczKGh? MoPQSG1UVw>? M37iWWlEPTB;MD6xPEDPxE1? MXyyOFE2OzJyNh?=
MCF-7 Mkj6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3TWdlEh|ryP MUm3NkBp NXy1e|FjTE2VTx?= NUfLV4dsUUN3ME2wMlE{KM7:TR?= MYiyOFE2OzJyNh?=
MCF10A M37yVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkX1NUDPxE1? NW\YXlUxPzJiaB?= NF;tcZlFVVOR MYDJR|UxRTBwMkmg{txO MXqyOFE2OzJyNh?=
HEK-293 Mn3XT4lv[XOnIFHzd4F6 NGD3WJozKGGwZDCyNEDPxE1? NHPTW3AzKGh? NGDYVmVFVVOR MojuTY5pcWKrdIOgR4hVNUxiYXP0bZZqfHlid3n0bEBKSzVyIH;mJFkhdk1i M2DkTlI{PTRyN{mw
Calu6 NWX1SHhETnWwY4Tpc44hSXO|YYm= M{HVNlExKM7:TR?= Mn7YNVghcA>? MXPEUXNQ NHfVd25UcWewaX\pZ4FvfGy7IHHjZ5VufWyjdHXzJIZz[XSjeHnuJJBz\WO3coPvdi=> M3z6V|I{PTB4NEi2
IFN-gamma-induced RAW264.7 M1O1c2Z2dmO2aX;uJGF{e2G7 MYLEUXNQ NH;Bc2NKdmirYnn0d{BvcXS{aXOgc5hq\GVicILv[JVkfGmxbjD3bZRpKEmFNUCgc4YhOC5yN{eg{txO NVqyZ3JkOjJ{N{eyO|c>
IPC227F MVHDfZRwfG:6aXOgRZN{[Xl? M3;RUVEh|ryP MmCzOFghcA>? NH\McGRFVVOR NHfIVI1KSzVyPUCuNFc4KM7:TR?= NGDLfJIzOTl{NEWyPC=>
Hepa-1c1c7 MlzLSpVv[3Srb36gRZN{[Xl? NVe5UINrOjVizszN NHXSfms3KGh? NYjVXpBsTE2VTx?= MY\JcoNz\WG|ZYOgUpJnOiCycn;0[YlvKGyndnXs NISzOJAzODN7MkW0OC=>
COS-7 NGrNO4NEgXSxdH;4bYMhSXO|YYm= NITl[oMyOCEQvF2= NFz5RWlFVVOR MVTJR|UxRDFyIN88US=> MVixPFA5QDB7Nx?=
HuH-7 NWHZSHd2S3m2b4TvfIlkKEG|c3H5 NUjwOXJWOTBizszN MUPEUXNQ M3\ZTGlEPTB:MUCg{txO MWmxPFA5QDB7Nx?=
OCI-Ly3 MmnaSpVv[3Srb36gRZN{[Xl? M2r2NlExKM7:TdMg NHPkelY1KGh? M1XPd2ROW09? NVy5SXlmUW6mdXPld{BpfW2jbjDJb4FxeGGEYXzwbIEhe3SjYnnsbZpifGmxbjD3bZRpKEWFNUCgc4YhOSEQvF2= NYHpSpdbOThyMkSxNVM>
A2780 cDDP M2\K[2Fxd3C2b4Ppd{BCe3OjeR?= NIXpc3YzPCCq NYHLfVFLTE2VTx?= MX;JcoR2[2W|IHHwc5B1d3OrczDifUBqdmirYnn0bY5oKFCWRV6g[IVoemGmYYTpc44> MWexO|Y5PDBzOB?=
LPS-stimulated RAW264.7 cells MnjwSpVv[3Srb36gRZN{[Xl? MnnJSG1UVw>? NGjqeo1KdmirYnn0d{BPTi2tYYDwZWIhTE6DIHLpcoRqdmd? NHHY[XMyPzRyN{K3Oy=>
PC12 NHTIfpVHfW6ldHnvckBCe3OjeR?= NF\4OJQyODBizszNxsA> M1zp[|I1KGh? MmK2SG1UVw>? Ml3pTY5pcWKrdIOgOk1QUESDLTDhcoQhUDKRMj3pcoR2[2WmIHP5eI91d3irY3n0fS=> MlzzNVcyPTh2NUS=
PC3 M4\XUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkLyNlAh|ryP MnK3OFghcA>? MnXFSG1UVw>? M2Th[mlEPTB;MD62JO69VQ>? MkO5NVY3QDZ3M{e=
LP-1 NHrlcHhCeG:ydH;zbZMhSXO|YYm= MnvFN|AxKG6P MlPCNlQhcA>? MYHEUXNQ MUDJcoR2[2W|IHHwc5B1d3OrczDifUBqdmO{ZXHzbY5oKGOuZXH2[YQhWEGUUDDs[ZZmdCCjbnSgdoVlfWOrbnegUYNtNTFicILveIVqdiCuZY\lcC=> MmfDNVU6PTh3OEm=
ES6 NYTWe5ZYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDITWM2OD1yLkCxN|A3KM7:TR?= NIrUT|lUSU6JRWK=
A101D NEnT[JdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYjJR|UxRTBwMEOyO|kh|ryP M4ntfXNCVkeHUh?=
OCUB-M M4jKfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXTaRZlFUUN3ME2wMlA{PzN5IN88US=> Ml;sV2FPT0WU
LB2518-MEL NEfweo1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2jPSWlEPTB;MD6wN|c3KM7:TR?= Ml7WV2FPT0WU
SH-4 NFPYPFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTBwMESzNUDPxE1? M33nZ3NCVkeHUh?=
KNS-42 NXnmRVRFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MU\JR|UxRTBwMES0OFEh|ryP NUXh[VFtW0GQR1XS
DSH1 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jpT2lEPTB;MD6wOVI5QSEQvF2= NXHxSIJqW0GQR1XS
NTERA-S-cl-D1 Ml:1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjaTWM2OD1yLkC1O|czKM7:TR?= Mke4V2FPT0WU
D-542MG MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2rtTWlEPTB;MD6wOVk2PyEQvF2= Mkj3V2FPT0WU
KS-1 M2XvRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTBwME[0OVgh|ryP M3;OWnNCVkeHUh?=
BL-41 Mnf3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTBwME[5OFch|ryP NX36XJk4W0GQR1XS
LXF-289 MnnPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmLuTWM2OD1yLkC3NFY3KM7:TR?= NIn2TFdUSU6JRWK=
D-247MG M1HwNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmXTTWM2OD1yLkC3NlA6KM7:TR?= MmL6V2FPT0WU
MMAC-SF NILXTW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHLPe45KSzVyPUCuNFczPjhizszN NV\4RYxrW0GQR1XS
CP66-MEL NWfWZlJvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHv1WZpKSzVyPUCuNFc2KM7:TR?= NFjacpBUSU6JRWK=
LB771-HNC MljjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;CTWM2OD1yLkC4NFM3KM7:TR?= Mlr3V2FPT0WU
no-10 NV74XWtiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PL[2lEPTB;MD6wPFkxQSEQvF2= MVHTRW5ITVJ?
A388 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmniTWM2OD1yLkC5NFY2KM7:TR?= MXTTRW5ITVJ?
OPM-2 NYDxWIVTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3;hNGlEPTB;MD6xNFQ4PCEQvF2= NWjRPYxPW0GQR1XS
OVCAR-4 M3[1Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlfUTWM2OD1yLkGwPVM5KM7:TR?= NHTZXnVUSU6JRWK=
HOP-62 NV;2dZpbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnTWTWM2OD1yLkGwPVQ6KM7:TR?= NFPJXYZUSU6JRWK=
ML-2 NGDsNWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3X[oQ1UUN3ME2wMlEyQDB4IN88US=> MWLTRW5ITVJ?
UACC-257 M{jz[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTBwMUG5Nlch|ryP NHjsZ2hUSU6JRWK=
NEC8 NHfTZ4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjveVB3UUN3ME2wMlEyQTl3IN88US=> NGj3S49USU6JRWK=
ONS-76 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7lUJJVUUN3ME2wMlEzQTN3IN88US=> M3XOZ3NCVkeHUh?=
KE-37 NYTBPHBlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjJdI1KSzVyPUCuNVMzPzhizszN M4\FW3NCVkeHUh?=
HT-144 Mo\uS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TEbGlEPTB;MD6xN|g6PSEQvF2= Mke3V2FPT0WU
LB2241-RCC MnTYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXzIcGs{UUN3ME2wMlE1OjR5IN88US=> MnH0V2FPT0WU
TE-5 MmezS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIPycI5KSzVyPUCuNVQzPzhizszN M3XYVXNCVkeHUh?=
KINGS-1 NGTZfVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXXSV4ZNUUN3ME2wMlE1PzlizszN M1XnVXNCVkeHUh?=
NCI-H69 MkG1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnLQTWM2OD1yLkG1NVQyKM7:TR?= M{DNRnNCVkeHUh?=
CAS-1 Mnr1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3\NUWlEPTB;MD6xOVQ5OiEQvF2= NHm5[3ZUSU6JRWK=
D-263MG MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2XIPGlEPTB;MD6xOlAxPiEQvF2= MYDTRW5ITVJ?
A253 M1HxS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mmq4TWM2OD1yLkG2NVI5KM7:TR?= NX31cFBuW0GQR1XS
PF-382 NH\tV5lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4nLcGlEPTB;MD6xOlcxPiEQvF2= NEPjTmVUSU6JRWK=
CESS NFzmbZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX3iUGtYUUN3ME2wMlE4ODZizszN NFLX[49USU6JRWK=
MZ2-MEL MmLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfQTWM2OD1yLkG3OVU6KM7:TR?= MUPTRW5ITVJ?
HEL NFHGe3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYjJR|UxRTBwMUi1NVch|ryP Mk\zV2FPT0WU
D-392MG NGrpdIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxRTBwMUmxNVUh|ryP MX\TRW5ITVJ?
SK-LMS-1 M2nrUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFmzRXBKSzVyPUCuNVk{ODNizszN NV7MS3pOW0GQR1XS
GI-ME-N MlzKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFjQTJhKSzVyPUCuNVk{ODZizszN NY\SN2NCW0GQR1XS
LB831-BLC NV[wSVJqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjC[FRKSzVyPUCuNVk{PCEQvF2= NUfrPIVCW0GQR1XS
DU-4475 NFrWWFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHHBZnRKSzVyPUCuNVk3PThizszN NY\CW4cxW0GQR1XS
IST-SL1 MmHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHLXFNKSzVyPUCuNlAxQTRizszN NWnURXF4W0GQR1XS
GAK MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXjJR|UxRTBwMkC1N|Qh|ryP M1r4WXNCVkeHUh?=
EW-1 MkTDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MofCTWM2OD1yLkKxNFQ4KM7:TR?= MXLTRW5ITVJ?
LAMA-84 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIHHR4dKSzVyPUCuNlE5PTFizszN NI\OcHdUSU6JRWK=
SK-UT-1 NUjNeXo6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVfJR|UxRTBwMkKwOFkh|ryP Mm\VV2FPT0WU
VA-ES-BJ M4XIeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTBwMkKyOVch|ryP NGOxXFRUSU6JRWK=
ACN M4m5Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTBwMkK2N|gh|ryP MXLTRW5ITVJ?
SK-PN-DW MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{f1VmlEPTB;MD6yN|E6KM7:TR?= M4TUOnNCVkeHUh?=
HD-MY-Z MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2TuUmlEPTB;MD6yN|MxOyEQvF2= MXTTRW5ITVJ?
LB373-MEL-D NUC1epZJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnfnTWM2OD1yLkK0NVk5KM7:TR?= NEP2WnhUSU6JRWK=
COLO-829 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnHlTWM2OD1yLkK0NlU4KM7:TR?= NEC3RmZUSU6JRWK=
ES8 M{X3PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX;JR|UxRTBwMkS3OlMh|ryP M3XFc3NCVkeHUh?=
RXF393 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17aNmlEPTB;MD6yOVAyPSEQvF2= MojoV2FPT0WU
TK10 M3zIU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3vob2lEPTB;MD6yOVQ{PSEQvF2= NUHKOVN[W0GQR1XS
LOUCY MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWrJR|UxRTBwMkW0OVYh|ryP MUDTRW5ITVJ?
MZ7-mel MoLhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV2xUWJvUUN3ME2wMlI3Ozd2IN88US=> M1vrW3NCVkeHUh?=
CP67-MEL M131fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mkj2TWM2OD1yLkK2O|Mh|ryP NW\OVoxxW0GQR1XS
C2BBe1 NYDGO2s6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3e5TWlEPTB;MD6yO|kxPyEQvF2= M17hXHNCVkeHUh?=
K052 NV;BZWZyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4j6XGlEPTB;MD6yPFk6KM7:TR?= M1zLNnNCVkeHUh?=
MOLT-16 NV;Cd4dsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnnTTWM2OD1yLkK5OVI1KM7:TR?= NWfxSXcyW0GQR1XS
KNS-81-FD NGfGfIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;mcWpKSzVyPUCuN|A{OjNizszN MkOxV2FPT0WU
CMK NUfZOJBDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTBwM{GxNkDPxE1? NVv5NnB6W0GQR1XS
LAN-6 NXfadllwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4rFN2lEPTB;MD6zNVMh|ryP NVm5[oQxW0GQR1XS
KLE NWLSeW9uT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7i[3hKSzVyPUCuN|E{ODZizszN NIKyd5RUSU6JRWK=
NCCIT MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX;WfmVnUUN3ME2wMlMyPzh|IN88US=> MV7TRW5ITVJ?
HH MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELkSoZKSzVyPUCuN|I5QTdizszN Mm\HV2FPT0WU
TE-8 NUL6fZBpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXrRc2xxUUN3ME2wMlM1Ojd7IN88US=> MX\TRW5ITVJ?
GDM-1 M1m2XWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWfJR|UxRTBwM{WxNFQh|ryP MWLTRW5ITVJ?
NCI-H747 NVPnTHljT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjUT3JKSzVyPUCuN|cyODNizszN MWnTRW5ITVJ?
NCI-H1092 MlrRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI\NeYJKSzVyPUCuN|g5PDRizszN M1LscXNCVkeHUh?=
8-MG-BA MojiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LKfWlEPTB;MD6zPVg{PyEQvF2= MlfIV2FPT0WU
NB17 NYDYVXhET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTBwNEK5O{DPxE1? NV3ae2lXW0GQR1XS
LC4-1 NU\5fnJJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnKTWM2OD1yLkSzOlA4KM7:TR?= NGXrOY5USU6JRWK=
TE-1 Mn\NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHocmpUUUN3ME2wMlQ2OTF7IN88US=> MV3TRW5ITVJ?
KALS-1 NFrh[o9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkniTWM2OD1yLkS2OVg1KM7:TR?= NYr6dYhyW0GQR1XS
CCRF-CEM NF\BZVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDnUoNKSzVyPUCuOFc3PzRizszN M{XtfXNCVkeHUh?=
OS-RC-2 NUGyT5lRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTBwNEe5O|Ih|ryP M{H6d3NCVkeHUh?=
A704 Mn3ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnS3TWM2OD1yLkS4OlkzKM7:TR?= MWPTRW5ITVJ?
BB49-HNC NFHoWZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;VbG1KSzVyPUCuOFkxQTZizszN MmrMV2FPT0WU
EVSA-T MmHrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTBwNEm5NVEh|ryP MnXOV2FPT0WU
Mo-T MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M370RmlEPTB;MD61NVc3OiEQvF2= M1rzO3NCVkeHUh?=
MONO-MAC-6 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWm5d4ViUUN3ME2wMlU{PjFzIN88US=> NYjiPYtrW0GQR1XS
BB65-RCC Ml3uS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYHJR|UxRTBwNU[4NVEh|ryP NH2wdFBUSU6JRWK=
NCI-H1882 NXPnTlA6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{G2[2lEPTB;MD61PVA{PiEQvF2= M3HSVHNCVkeHUh?=
TE-9 NX3sNHo2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVXJR|UxRTBwNkGwN|Mh|ryP NVvO[IhuW0GQR1XS
NCI-H2126 NWLHNmMxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrXTWM2OD1yLk[yOlY6KM7:TR?= MVvTRW5ITVJ?
SF268 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml3tTWM2OD1yLk[1OlQyKM7:TR?= NX;HVmQ2W0GQR1XS
SW872 MknuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmK1TWM2OD1yLk[1O|I6KM7:TR?= MYfTRW5ITVJ?
LS-513 M3z1V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\vPGlEPTB;MD62Olc2OSEQvF2= NXnpSmh7W0GQR1XS
NCI-H1355 NYroS5FHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTBwNki2NVkh|ryP MnfQV2FPT0WU
BL-70 M2Dzemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVTmVZlpUUN3ME2wMlY6Ozh6IN88US=> NVLofnZPW0GQR1XS
NCI-SNU-5 NUDQXoVjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH3oPIlKSzVyPUCuOlk2PDVizszN MnPxV2FPT0WU
SNU-C2B MlrjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HURWlEPTB;MD63NFc{QSEQvF2= NGjwbIFUSU6JRWK=
GB-1 MlLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MonPTWM2OD1yLkeyNVI1KM7:TR?= MVHTRW5ITVJ?
CTB-1 NWPuNopRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\pTYxZUUN3ME2wMlc4QTV3IN88US=> NIfHcJNUSU6JRWK=
Becker Mn;zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTOTVVOUUN3ME2wMlc6PjJzIN88US=> MlO5V2FPT0WU
KM12 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmC1TWM2OD1yLki1OFY3KM7:TR?= M2LRNnNCVkeHUh?=
ES7 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2DmS2lEPTB;MD64PVY2KM7:TR?= M4XyWXNCVkeHUh?=
COLO-684 NWT5VWppT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnL3TWM2OD1yLkmwOlU5KM7:TR?= MofyV2FPT0WU
HCC2998 MlrpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEK5Z21KSzVyPUCuPVM5PTRizszN MYjTRW5ITVJ?
TE-10 NHPKO2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HzUmlEPTB;MD65OlQ{KM7:TR?= M3TibnNCVkeHUh?=
SF126 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVvkSWoxUUN3ME2wMlk5QTdzIN88US=> NETB[4dUSU6JRWK=
EKVX M4rKcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MonrTWM2OD1zLkCzOFQzKM7:TR?= NX;nfZA4W0GQR1XS
KARPAS-45 M4fIPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEPYXFlKSzVyPUGuNFQxOTZizszN M1PQVHNCVkeHUh?=
KGN MoP0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmTETWM2OD1zLkC1NFQ2KM7:TR?= M1y0fnNCVkeHUh?=
ES1 M4rsNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEHaPGVKSzVyPUGuNFc6OjFizszN MUXTRW5ITVJ?
L-540 M3zC[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUfJR|UxRTFwMUG4N|kh|ryP NFnoW2JUSU6JRWK=
KURAMOCHI NUK1VHIyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTFwMUKzO|Qh|ryP NX3QTm1QW0GQR1XS
LU-65 MnLCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1nzbGlEPTB;MT6xNlc2OyEQvF2= MoPsV2FPT0WU
MFH-ino MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3tO2NKSzVyPUGuNVc2ODFizszN MUjTRW5ITVJ?
NCI-H23 Mn[2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEHaU4VKSzVyPUGuNlA1OSEQvF2= MYLTRW5ITVJ?
IA-LM MoPpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInhTFlKSzVyPUGuNlQyOTZizszN MXTTRW5ITVJ?
PSN1 NUjzUXJkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDBTWM2OD1zLkK3NFE3KM7:TR?= M1zyTHNCVkeHUh?=
NCI-H719 M3WwUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LpbGlEPTB;MT6yO|QyOSEQvF2= MW\TRW5ITVJ?
SW684 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVPJR|UxRTFwMki2OVkh|ryP MoG2V2FPT0WU
HCE-4 NFPpcIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHj5eodKSzVyPUGuN|AzOjFizszN MWHTRW5ITVJ?
EW-16 M{fDe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVXaOHIxUUN3ME2xMlMyOzR5IN88US=> NGjZcmRUSU6JRWK=
NCI-H128 NIPXU45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3rCOGlEPTB;MT6zOVgyPCEQvF2= NUHOSVg{W0GQR1XS
HC-1 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml3LTWM2OD1zLkO4NVch|ryP MmDNV2FPT0WU
IST-MES1 M{DIU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVrJR|UxRTFwNECyNFgh|ryP NYXTe5V7W0GQR1XS
Raji NVfQUIx5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1XI[2lEPTB;MT60NVg2KM7:TR?= MVrTRW5ITVJ?
DMS-114 M2OwUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NG[xWo5KSzVyPUGuOFQ2OzlizszN NIC4PXRUSU6JRWK=
GI-1 M3fXVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVH1PYZ4UUN3ME2xMlQ4OTNzIN88US=> NWryZ|EzW0GQR1XS
NCI-H2081 M1H5U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3HUo9lUUN3ME2xMlU2OTl4IN88US=> NFjtWYtUSU6JRWK=
LC-1F NFHzUndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHr1[mpKSzVyPUGuOVUyQThizszN Mo\rV2FPT0WU
NCI-H2227 NVXTVIloT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTFwNkG1OlEh|ryP NFi5UHpUSU6JRWK=
D-502MG M4nqVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlGxTWM2OD1zLk[3NlEyKM7:TR?= NVG2ZYZSW0GQR1XS
NCI-H2141 MmLYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3Lzd2lEPTB;MT62O|MyPyEQvF2= NWfh[mZUW0GQR1XS
LS-411N MnTDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrqTWM2OD1zLk[5PFA4KM7:TR?= NXLk[WZ2W0GQR1XS
SU-DHL-1 NFnXcW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFS4SWxKSzVyPUGuO|EzQDFizszN MoG0V2FPT0WU
BB30-HNC NWLtOVBwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXrDfldvUUN3ME2xMlczPjh3IN88US=> NXyxNo9KW0GQR1XS
TE-15 NIXwPYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUTFcmJ7UUN3ME2xMlkzOzd|IN88US=> NHfBS4VUSU6JRWK=
JVM-3 M2DTb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml3yTWM2OD1zLkmzPVA1KM7:TR?= NYHxXHQ5W0GQR1XS
IST-SL2 NYXCW|llT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIrvSIJKSzVyPUKuNFEzPTJizszN MV7TRW5ITVJ?
EW-18 M1yzVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTJwMEKzN|ch|ryP NEH2d4JUSU6JRWK=
DJM-1 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFzSNlhKSzVyPUKuNFI2PTJizszN MlWyV2FPT0WU
no-11 NX\zWGExT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGT0[ZRKSzVyPUKuNFMyODRizszN MnnCV2FPT0WU
QIMR-WIL M{XNUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1zDWGlEPTB;Mj6xOlc3OiEQvF2= M{G0c3NCVkeHUh?=
MC-CAR NUfIPJpWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jPSmlEPTB;Mj6yNlk2KM7:TR?= M3jmO3NCVkeHUh?=
KM-H2 Mm\ES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFeyd5lKSzVyPUKuNlkxPDNizszN M4D3fHNCVkeHUh?=
ECC12 NWjST3NrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTm[ZpyUUN3ME2yMlM4QTRizszN NH62VohUSU6JRWK=
HCE-T NHzVe3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vGTWlEPTB;Mj60OFg5OyEQvF2= NYnwSWN3W0GQR1XS
MFM-223 NXXxTJcxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIK3WFVKSzVyPUKuOVA5PzFizszN M323XHNCVkeHUh?=
SW982 NFzpRXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHxT2NKSzVyPUKuOVE1QCEQvF2= M3zN[nNCVkeHUh?=
KG-1 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYHJR|UxRTJwOEi3PVEh|ryP MlTpV2FPT0WU
ES4 NW\Pc|d[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{O5bmlEPTB;Mz6wOlEyOSEQvF2= MXXTRW5ITVJ?
SCC-3 NX\VcI5tT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;J[nBIUUN3ME2zMlExQDR6IN88US=> MXzTRW5ITVJ?
RH-1 NFX6WYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXLOZYJjUUN3ME2zMlM5PzR6IN88US=> Mn[wV2FPT0WU
NCI-H748 Mln5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHP1V3dKSzVyPUOuOFQzPjZizszN MVLTRW5ITVJ?
HCC2218 NVHyOYZjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWO1SXRPUUN3ME2zMlQ3QTN5IN88US=> NEfodm5USU6JRWK=
MEG-01 NV:0W41VT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYOxUlZkUUN3ME2zMlU6PjhizszN NGX4RY9USU6JRWK=
NB12 NFTqeXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH35Zm1KSzVyPUOuOVk5QDhizszN Mnf5V2FPT0WU
SNB75 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYjEUWdYUUN3ME2zMlYxOTB|IN88US=> MVPTRW5ITVJ?
KMS-12-PE MkS5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\YSGlEPTB;Mz62O|czOyEQvF2= M{PyWnNCVkeHUh?=
SKM-1 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHCTWM2OD1|LkexN|c3KM7:TR?= NF7BS|lUSU6JRWK=
COLO-320-HSR MmHMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3S5VWlEPTB;Mz63OVY{PCEQvF2= MoqwV2FPT0WU
NKM-1 NXPuN3lQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTNwN{ezO|gh|ryP MmC4V2FPT0WU
TE-6 M33ZSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoOwTWM2OD1|Lkm0OVYyKM7:TR?= NEL4WWNUSU6JRWK=
D-336MG M1;ib2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTRwMEGxOlYh|ryP NUXrN2IyW0GQR1XS
NCI-H1650 M4XUTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUjvRXhPUUN3ME20MlE2Pzl5IN88US=> MknzV2FPT0WU
ES3 Mlz1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlfKTWM2OD12LkOyPFI1KM7:TR?= NWX2NXZWW0GQR1XS
YT NY\XeoMyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fNVGlEPTB;ND6zOVQzPCEQvF2= NYO5S4J6W0GQR1XS
ES5 M1PCfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2DMbGlEPTB;ND60NFI2PSEQvF2= Ml;kV2FPT0WU
LB647-SCLC M1foRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlvOTWM2OD12LkW2N|A5KM7:TR?= M2LycHNCVkeHUh?=
HAL-01 NXHxU|FYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXPJR|UxRTRwNUewN|Qh|ryP NIWyOZNUSU6JRWK=
LP-1 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml3DTWM2OD12LkeyN|cyKM7:TR?= NVLkdFRzW0GQR1XS
BC-1 NUDnOoo3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDETWM2OD13LkCwOFQ4KM7:TR?= MYrTRW5ITVJ?
EB-3 Mlz0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTVwMEOwOFEh|ryP M4C3ZnNCVkeHUh?=
GT3TKB Mn3zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2XydWlEPTB;NT6xO|Y3OiEQvF2= NUHSZnVlW0GQR1XS
NCI-H209 NEPJTIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTLU4J3UUN3ME21MlE6OzV{IN88US=> NXPySop1W0GQR1XS
BT-474 NH\yO2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWDJR|UxRTVwMkOxNFIh|ryP MX\TRW5ITVJ?
RKO MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIrlPIJKSzVyPUWuNlM1OjJizszN NICydVVUSU6JRWK=
SIMA NEnMW|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFn1WVdKSzVyPUWuN|A4PjVizszN M3rjbnNCVkeHUh?=
RL MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX7SU2J6UUN3ME21MlM4PTRzIN88US=> NYfCbodIW0GQR1XS
GCIY MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXvJR|UxRTVwNEeyN|Yh|ryP MnHrV2FPT0WU
Calu-6 MnLxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1nHeWlEPTB;NT62NlIh|ryP MV3TRW5ITVJ?
ALL-PO NGHYboRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVvJR|UxRTVwNkO3PVUh|ryP NVPDTHFnW0GQR1XS
ARH-77 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlH4TWM2OD13Lk[3NFg4KM7:TR?= NUPHOJJNW0GQR1XS
A4-Fuk MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYXJR|UxRTZwMEixNVgh|ryP NVXmbmN{W0GQR1XS
NCI-H1581 M4\H[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrOcppZUUN3ME22MlI{QDR7IN88US=> NVnBPZl2W0GQR1XS
HUTU-80 MoDkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXrJR|UxRTZwM{[4PVch|ryP NHO2[VZUSU6JRWK=
TGW MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIHibYxKSzVyPU[uOFU2QTNizszN MWPTRW5ITVJ?
SK-N-FI NUPMbGRTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTZwNEW4OVQh|ryP MkT6V2FPT0WU
U-266 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUXJR|UxRTZwNUG5NlYh|ryP NX\EOnpTW0GQR1XS
EM-2 MlHtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HvVGlEPTB;Nj62O|A6QSEQvF2= MX7TRW5ITVJ?
NMC-G1 NVe2R2xkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVfuZWlMUUN3ME22MlcyQDl3IN88US=> Mlq5V2FPT0WU
KASUMI-1 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTZwOES3PFch|ryP NWO2WIl[W0GQR1XS
NALM-6 NHT6U2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTZwOE[3OVQh|ryP NVTQTpYxW0GQR1XS
OCI-AML2 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjSTWM2OD15LkCwN|I3KM7:TR?= NITvSY5USU6JRWK=
SHP-77 M3vicWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1v1SGlEPTB;Nz6yNlQ{KM7:TR?= NV;RbWtwW0GQR1XS
NOMO-1 NX3KfINZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnKfmU4UUN3ME23MlI1OjV2IN88US=> M1e4e3NCVkeHUh?=
SK-N-DZ NFHhN4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\zTWM2OD15LkexNFg6KM7:TR?= M2rXd3NCVkeHUh?=
LB1047-RCC MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{THSWlEPTB;Nz63NlI{OSEQvF2= NIDGVGJUSU6JRWK=
MZ1-PC NH3LbVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MY\JR|UxRTdwOE[1OVgh|ryP MnTjV2FPT0WU
NB10 MoDCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoLJTWM2OD15Lkm5OVU3KM7:TR?= NX;hOXlyW0GQR1XS
RL95-2 NETPdlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljqTWM2OD16LkGwPFQzKM7:TR?= NYHnPJlYW0GQR1XS
OMC-1 MnLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nqXWlEPTB;OD61NlE6OSEQvF2= Ml\2V2FPT0WU
D-283MED NYnDdHRRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{HzTWlEPTB;OD65NVcyQSEQvF2= NFfKRZhUSU6JRWK=
MC116 NYXjfFR1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnEWIxjUUN3ME24Mlk4QTRizszN MYLTRW5ITVJ?
SJSA-1 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1LvWGlEPTB;OT6wPVA6OSEQvF2= MmHSV2FPT0WU
JiyoyeP-2003 Mn\MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3zzSmlEPTB;OT6yPVMyPyEQvF2= M{G4VnNCVkeHUh?=
IST-MEL1 MkXGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3roVWlEPTB;OT63OFE6QCEQvF2= M1K0enNCVkeHUh?=
CTV-1 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGXiRWRKSzVyPUGwMlA6PzlizszN MXLTRW5ITVJ?
NH-12 M4\ybmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTFyLkK0N|Mh|ryP MYjTRW5ITVJ?
CA46 Mkf3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mor0TWM2OD1zMD6zOlEh|ryP MWnTRW5ITVJ?
NCI-SNU-1 Ml\aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUjJR|UxRTFyLkS5Olkh|ryP MVTTRW5ITVJ?
SCLC-21H MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGm5WFJKSzVyPUGwMlY2QTZizszN NWPifXN5W0GQR1XS
EC-GI-10 M4fNc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLacHBKSzVyPUGwMlcxOzFizszN MYDTRW5ITVJ?
SR M{\QS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M174fmlEPTB;MUGuNFE5PSEQvF2= MlnJV2FPT0WU
NCI-H1648 M4\jSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXLJR|UxRTFzLkC5OlUh|ryP NYXhZmpoW0GQR1XS
TGBC1TKB NHL0dlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEDkS4VKSzVyPUGxMlQyODJizszN MnHHV2FPT0WU
EW-11 M2D4WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYjQWnNMUUN3ME2xNU42OTh4IN88US=> NIS1[ZhUSU6JRWK=
SK-MM-2 NWO4bW45T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEi3cZpKSzVyPUGxMlgxPjFizszN MmDSV2FPT0WU
NCI-H524 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\CTHZEUUN3ME2xNU46QDJ{IN88US=> NEX3O4tUSU6JRWK=
NOS-1 MkCwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTuNIJJUUN3ME2xNk4xOzR3IN88US=> NWfIT3FPW0GQR1XS
AM-38 M2PHTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3SyN2lEPTB;MUKuOVY{OyEQvF2= M{C1PHNCVkeHUh?=
A498 NW\XRoRvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTF{LkewOlkh|ryP MYjTRW5ITVJ?
KARPAS-422 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTF{Lke0PVYh|ryP M{fQZnNCVkeHUh?=
LU-139 NWi3T2diT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\Vc2F4UUN3ME2xNk46ODJ4IN88US=> MVzTRW5ITVJ?
COR-L88 NVLVUlA4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTF{LkmzPFIh|ryP NFHnOoVUSU6JRWK=
K5 NUXwR2o2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFzXXIVKSzVyPUGyMlk1PjJizszN Mnr6V2FPT0WU
NB13 NILoSFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTF{Lkm3PFMh|ryP NF36R3ZUSU6JRWK=
MRK-nu-1 NVjzWYJxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEn4THJKSzVyPUGzMlE6PSEQvF2= NF73[WpUSU6JRWK=
MHH-NB-11 NET3Xm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXLQc4hbUUN3ME2xN{4zQTB{IN88US=> NY\nbpFUW0GQR1XS
KU812 M{GzeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnjWW9kUUN3ME2xN{43OTJ2IN88US=> MmfwV2FPT0WU
TE-12 NIOwVmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fXOmlEPTB;MUOuOlk6PCEQvF2= NGPBU5JUSU6JRWK=
NCI-N87 MlXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2[1WGlEPTB;MUOuO|M3KM7:TR?= NUH2[2dPW0GQR1XS
EB2 MmfGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1zucmlEPTB;MUOuPFUxPSEQvF2= NUfud2FJW0GQR1XS
DB M1PQfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX3pOVQxUUN3ME2xN{46QDh3IN88US=> NXLvSGVFW0GQR1XS
697 MonTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV7JR|UxRTF2LkS1NVEh|ryP MkXWV2FPT0WU
MSTO-211H MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTF2Lke0OFgh|ryP NF7OR2ZUSU6JRWK=
JVM-2 NUHmV2ZmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH3IeoFKSzVyPUG0Mlc4OzVizszN MmTUV2FPT0WU
COLO-824 NWnQUIpRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHnaenNKSzVyPUG0Mlc6QTRizszN NHHrWnRUSU6JRWK=
BC-3 NFjGbIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4jQWGlEPTB;MUWuN|k5KM7:TR?= Ml:zV2FPT0WU
BOKU MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfUeGpKSzVyPUG1Mlk3ODhizszN MVPTRW5ITVJ?
GOTO NVfIb3RIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH;VdJdKSzVyPUG2Mlk3OTdizszN NE\oNpdUSU6JRWK=
HCC2157 NWHa[ZJTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDQTWM2OD1zNz60O|U2KM7:TR?= M1\QcnNCVkeHUh?=
LS-1034 NUPGTHBuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NETXT4xKSzVyPUG3MlY5OThizszN NV3od29yW0GQR1XS
CAL-148 M{K2cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{S1WmlEPTB;MUeuPVc6PiEQvF2= NUP4[|V6W0GQR1XS
MOLT-4 NIq0cVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\6TWM2OD1zOD64NlA5KM7:TR?= NYHHUVNSW0GQR1XS
Daudi NEjITFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{jGbGlEPTB;MUiuPVI{OSEQvF2= NEfWR2VUSU6JRWK=
J-RT3-T3-5 M{fSPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlHkTWM2OD1zOT60NFY3KM7:TR?= M1vw[HNCVkeHUh?=
KMOE-2 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWrJR|UxRTF7Lk[0PFIh|ryP NFnab45USU6JRWK=
HL-60 NHmzeFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIT6b2JKSzVyPUKwMlE6PjVizszN M13KenNCVkeHUh?=
P31-FUJ NWTmUFNvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFHNN3dKSzVyPUKwMlQ4PTNizszN M4f0U3NCVkeHUh?=
IM-9 NWL6RW01T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYDOclRsUUN3ME2yNE43OjJ2IN88US=> MXvTRW5ITVJ?
HDLM-2 NWX4UZlFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVfJR|UxRTJyLki4NlEh|ryP MoHxV2FPT0WU
NCI-H1304 NXPEVnYzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\BXFJKSzVyPUKxMlA{OTFizszN MlPLV2FPT0WU
NCI-H345 MkHKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXPTZZlvUUN3ME2yNU4xPjR|IN88US=> MmPXV2FPT0WU
RPMI-6666 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NETzdW9KSzVyPUKxMlM3ODJizszN NIXKW5JUSU6JRWK=
GR-ST NV7Ye3B2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LY[mlEPTB;MkGuOFE4KM7:TR?= NVHMNpFlW0GQR1XS
CHP-126 MkD2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7CTWM2OD1{MT62NVgyKM7:TR?= NGXVTZdUSU6JRWK=
EHEB NIrNdVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\XcGk6UUN3ME2yNU43PzNzIN88US=> MVjTRW5ITVJ?
CPC-N M{LVfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnnETWM2OD1{ND6wNlAyKM7:TR?= MVTTRW5ITVJ?
NB1 NYHYc4hYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjCbpFKSzVyPUK0MlY6OzlizszN MVvTRW5ITVJ?
LS-123 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX\JR|UxRTJ2LkmwNVIh|ryP NH;uT3FUSU6JRWK=
ST486 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDCVFdOUUN3ME2yOU4yOTF|IN88US=> MVnTRW5ITVJ?
NCI-H1963 Mn\BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoOxTWM2OD1{Nj6wOlI{KM7:TR?= NE\kUmpUSU6JRWK=
U-87-MG Mo\SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\6bmlEPTB;Mk[uO|Y1PCEQvF2= MWHTRW5ITVJ?
COR-L279 M4XNNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NU\mb2FOUUN3ME2yOk44QTJ{IN88US=> MYfTRW5ITVJ?
LU-165 M1jmTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF3QemZKSzVyPUK4MlA5PjFizszN MnjsV2FPT0WU
COLO-800 M{m4fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxRTJ6LkK5OVYh|ryP Ml7aV2FPT0WU
ETK-1 M13oOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mon5TWM2OD1{OD6zOFQ3KM7:TR?= NUHxOYdxW0GQR1XS
LNCaP-Clone-FGC NI\VfXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLXO|BuUUN3ME2yPU46OjhzIN88US=> NXvOPHVqW0GQR1XS
SIG-M5 MlXxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M33RRmlEPTB;M{CuO|k2OiEQvF2= MnvCV2FPT0WU
NB6 NFrwSXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3W3TWlEPTB;M{CuPVUxOyEQvF2= M{nzWHNCVkeHUh?=
NCI-H2107 M2i3bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M17kW2lEPTB;M{GuNlM{QCEQvF2= NH\CUlBUSU6JRWK=
SNU-C1 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPh[lNKUUN3ME2zNU4{OTJ4IN88US=> NVvJ[ZJEW0GQR1XS
JAR NIPJ[|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3LKW2lEPTB;M{GuN|c6QSEQvF2= NF3BZ5dUSU6JRWK=
L-363 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrSU414UUN3ME2zNk4zOTR2IN88US=> MnrWV2FPT0WU
EW-24 MkDvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mnm3TWM2OD1|Mj6zOFc1KM7:TR?= M4rwTHNCVkeHUh?=
NB69 MoH1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTN|Lk[0OVQh|ryP MUHTRW5ITVJ?
EW-13 NEPGNppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3wbmd{UUN3ME2zN{45QTZ7IN88US=> NYLWO5ZUW0GQR1XS
Ramos-2G6-4C10 MoO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4LYN2lEPTB;M{SuNlk6OyEQvF2= MY\TRW5ITVJ?
TE-11 NF;rZ|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3OO2xyUUN3ME2zOE41QDJ{IN88US=> M2\KV3NCVkeHUh?=
L-428 NITCOIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFzYOIhKSzVyPUO0Mlc2OzZizszN NITE[HZUSU6JRWK=
KP-N-YN MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV7JR|UxRTN2LkmwOVch|ryP NXfqdHJnW0GQR1XS
CGTH-W-1 NEfybnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXX1VVFEUUN3ME2zOk46ODR6IN88US=> MUXTRW5ITVJ?
K-562 NFrxeIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYDwWXZxUUN3ME2zO{4xQDZ2IN88US=> NXi0eGd4W0GQR1XS
NCI-H1299 NWXGd5FiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1z3UWlEPTB;M{iuNVYxOyEQvF2= NYnUOotDW0GQR1XS
RCC10RGB MnnVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFXEWFhKSzVyPUO4MlIxQDNizszN Mli3V2FPT0WU
NCI-SNU-16 M2XMUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETUeW9KSzVyPUO4MlU3PTNizszN MnG3V2FPT0WU
LC-2-ad NHHicXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4XBOmlEPTB;M{muOFM{PyEQvF2= MVfTRW5ITVJ?
MHH-PREB-1 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFHNN29KSzVyPUO5Mlc{QDhizszN NE\5cIVUSU6JRWK=
NCI-H64 Mn7TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXn3cYl{UUN3ME20NE4xQTR6IN88US=> MUDTRW5ITVJ?
LB996-RCC NGXKVVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJR|UxRTRyLki3NVYh|ryP M3jmU3NCVkeHUh?=
DEL MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlv3TWM2OD12MT60OFA2KM7:TR?= NGjhUI9USU6JRWK=
MLMA NVO3ZYs3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mo\FTWM2OD12MT63OVk2KM7:TR?= NUnUSIdEW0GQR1XS
SBC-1 MonNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFLjfVBKSzVyPUSyMlE5ODZizszN MYrTRW5ITVJ?
MPP-89 MnfrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\1d2lEPTB;NEKuOVg4PSEQvF2= MXzTRW5ITVJ?
MV-4-11 NV\CZlZ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NG\nNmNKSzVyPUSyMlkxPjdizszN NH35fZdUSU6JRWK=
EoL-1- M4PUXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LLOmlEPTB;NESuNVU3QCEQvF2= NGfEcmRUSU6JRWK=
CW-2 NFvTSGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTR2LkizOFIh|ryP NG\wfoVUSU6JRWK=
HT M2LDRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFSzXWJKSzVyPUS1MlcxODdizszN MYHTRW5ITVJ?
SW954 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;rS2lEPTB;NEeuOFEzQCEQvF2= NELhdVNUSU6JRWK=
A3-KAW NFywbYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml\STWM2OD12OT64NFYyKM7:TR?= NVu5coZoW0GQR1XS
TC-YIK MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTsN2pKSzVyPUWwMlA{PjNizszN NHnscIxUSU6JRWK=
SW962 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILj[opKSzVyPUW0Mlg{PTdizszN M1\xcnNCVkeHUh?=
KP-N-RT-BM-1 NH;WW|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX3JR|UxRTV4Lk[2N|gh|ryP M2DTb3NCVkeHUh?=
NCI-H1395 NXfhW|RHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXHyb5hwUUN3ME21PE45OTd{IN88US=> NFrwbHpUSU6JRWK=
RPMI-8402 M1\kOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFrsZm5KSzVyPUW4Mlk2OjZizszN M{i0UnNCVkeHUh?=
SCH NYfVNnd3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmP3TWM2OD14MD65OlM5KM7:TR?= NWLWSIZoW0GQR1XS
NCI-H2196 M163Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Moe1TWM2OD14MT6yN|Eh|ryP MlPIV2FPT0WU
LOXIMVI M1\SZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIq2dmxKSzVyPU[xMlgzPjZizszN NGfQTodUSU6JRWK=
TGBC24TKB M2fid2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLnbXZKSzVyPU[yMlE1QTFizszN MWnTRW5ITVJ?
SK-MEL-2 Mmi4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTZ|Lkm4PVIh|ryP NHfUZWhUSU6JRWK=
U-698-M NH7idHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYLKeZNjUUN3ME22PE42Pjh5IN88US=> MmHoV2FPT0WU
NCI-H1522 MmDzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkTTTWM2OD14OT6wNFQ4KM7:TR?= NI\4NZpUSU6JRWK=
UACC-812 NFrmW2RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTZ7LkWyNFkh|ryP NEP5SWdUSU6JRWK=
MHH-CALL-2 MnfLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mnm3TWM2OD15MD6wOkDPxE1? NGHQR3NUSU6JRWK=
NB5 NIjLTXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXv4R5hzUUN3ME23NE4{PDZ6IN88US=> NVr0RlRuW0GQR1XS
KARPAS-299 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{XZZ2lEPTB;N{CuOFQ1PyEQvF2= NHfkbnZUSU6JRWK=
NCI-H1694 NVPBbWVlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUXJR|UxRTdzLkCzNkDPxE1? MljDV2FPT0WU
NCI-H82 MnfmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPWTWM2OD15MT65OVA4KM7:TR?= Mon5V2FPT0WU
SCC-15 M2KzWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn\TTWM2OD15Mj6zOEDPxE1? M1fvPXNCVkeHUh?=
NCI-H1436 MnvTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEC0PXhKSzVyPUeyMlc1PTZizszN M{jTb3NCVkeHUh?=
ATN-1 NH3CdFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXzJR|UxRTd2LkWwOUDPxE1? NE\Xe4ZUSU6JRWK=
RPMI-8866 MkOxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEDUW5NKSzVyPUe0Mlc2ODlizszN MlX4V2FPT0WU
HCC1599 M1rKfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWLJR|UxRTd2Lki3N|Ih|ryP MWfTRW5ITVJ?
NCI-H1155 NX\GZ|ZiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{TnNGlEPTB;N{SuPVM3PyEQvF2= NF;qTopUSU6JRWK=
DOHH-2 Mn3oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3P0TGlEPTB;N{SuPVUyPCEQvF2= NX[xd2VSW0GQR1XS
SK-NEP-1 NGTGbnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3kTWM2OD15NT6wO|U1KM7:TR?= NGC4RZNUSU6JRWK=
HCC1187 M2X2d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWLJR|UxRTd5Lk[xNlIh|ryP M4HWenNCVkeHUh?=
NCI-H322M NWjSSIN4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTd6LkO3NFkh|ryP NXrBXpE2W0GQR1XS
NCI-H526 M4PwUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXXXVIFoUUN3ME23PE42QDd5IN88US=> M2X2fnNCVkeHUh?=
NCI-H2171 MnfES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3YTWM2OD15OT60NVM3KM7:TR?= MXjTRW5ITVJ?
COLO-668 NE\HbYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzETWM2OD16MT61PFg1KM7:TR?= NXHUb2o{W0GQR1XS
RS4-11 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYnTdms1UUN3ME24Nk4zPTB3IN88US=> NXvEbFM3W0GQR1XS
NCI-H716 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjvUI5KSzVyPUiyMlkxPzVizszN M{ezdnNCVkeHUh?=
LU-134-A NXf2OGozT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTh|LkGzOVEh|ryP MWnTRW5ITVJ?
RPMI-8226 M1f1d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTh2LkKxNFch|ryP NXnye3o2W0GQR1XS
KY821 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlzxTWM2OD17MT62OVUyKM7:TR?= NVvqUmx7W0GQR1XS
ECC4 Mof2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPSTWM2OD17Mz64NlY6KM7:TR?= MmflV2FPT0WU
EW-3 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTl2LkmwPFEh|ryP NF7vSZNUSU6JRWK=
NB7 NHnKTWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX65N29OUUN3ME25OU44Pzh4IN88US=> M{\QOnNCVkeHUh?=
NCI-H720 MmDnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX;JR|UxRTl6LkSwOlEh|ryP MnHIV2FPT0WU
NCI-H446 MlrhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTl7Lke1PFgh|ryP NUPFeY9EW0GQR1XS
NCI-H889 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3zDbmlEPTB;MUC0MlI1OiEQvF2= NGLnWVVUSU6JRWK=
EW-22 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1TFfmlEPTB;MUC2MlE6KM7:TR?= M17iSnNCVkeHUh?=
BV-173 NXHtSoxJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTJOJl[UUN3ME2xNFgvPzJ6IN88US=> MX;TRW5ITVJ?
WSU-NHL NULPS|J6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTFyOT62O|Eh|ryP NVT6bWt3W0GQR1XS
MN-60 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUDNS3MyUUN3ME2xNFkvPjlizszN M2XsT3NCVkeHUh?=
DG-75 NWnaTnVkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXruT29{UUN3ME2xNVMvOzV{IN88US=> Mk\WV2FPT0WU
DMS-79 Ml\iS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;Y[4ZJUUN3ME2xNVcvOzh{IN88US=> NGLib5FUSU6JRWK=
SK-MEL-1 NWWxfVRWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnJZZV7UUN3ME2xNVgvODB7IN88US=> NWXxN4UyW0GQR1XS
DMS-153 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX7ySGljUUN3ME2xNlEvPzR3IN88US=> MU\TRW5ITVJ?
NCI-H510A NGfNOGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrUT4RKSzVyPUGyO{4{OiEQvF2= Mo\6V2FPT0WU
BE-13 NIDLVnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTF|ND6wOFQh|ryP MkTTV2FPT0WU
KP-N-YS MlW1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrXZmJKSzVyPUGzPU44OzZizszN MVTTRW5ITVJ?
SUP-T1 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\McGlEPTB;MUSzMlcxQCEQvF2= M3n3XXNCVkeHUh?=
EW-12 NVH6UpltT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1Wzd2lEPTB;MUS0MlY6QSEQvF2= M1m0e3NCVkeHUh?=
NB14 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYjJR|UxRTF2Nz6wPFIh|ryP MXLTRW5ITVJ?
MDA-MB-134-VI NGmx[ZZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{T5bmlEPTB;MUS4MlI3QCEQvF2= MY\TRW5ITVJ?
NCI-H1770 NEmxdWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFu4PXVKSzVyPUG1Ok4zPzlizszN NHv1UlJUSU6JRWK=
TUR NITpNVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjlTWM2OD1zNkeuPFch|ryP MW\TRW5ITVJ?
NCI-H1417 NV;6[JAxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWnJR|UxRTF6MD6zN|Eh|ryP MYPTRW5ITVJ?
IMR-5 MonzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXzHcmlrUUN3ME2xPFEvPTdzIN88US=> NHSzW4lUSU6JRWK=
NCI-H226 MkDZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M17YWGlEPTB;MUi4Mlg3PiEQvF2= NID1RndUSU6JRWK=
NCI-H187 NFzTTVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjpeFMzUUN3ME2xPVAvODZ2IN88US=> MV;TRW5ITVJ?
SF539 NFrHdnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3kTWM2OD1zOUKuO|I5KM7:TR?= M3jIN3NCVkeHUh?=
TALL-1 Mkf5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXvfFc3UUN3ME2xPVgvOzB2IN88US=> MkjkV2FPT0WU
TE-441-T MmK1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Moe3TWM2OD1zOUmuO|M6KM7:TR?= MnvlV2FPT0WU
REH MlLRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfjTWM2OD1{M{[uOlI3KM7:TR?= NGixW5JUSU6JRWK=
MS-1 Ml3VS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFTvXWhKSzVyPUKzPU4yOjFizszN MnWyV2FPT0WU
THP-1 NXfsOHNRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU[xPJhnUUN3ME2yOlQvPzN6IN88US=> M3H3cHNCVkeHUh?=
NCI-H1838 NFHv[|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTJ5MT60OVYh|ryP M1;TUXNCVkeHUh?=
P30-OHK M2TIR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTJ6Mz64OFch|ryP NXHKT405W0GQR1XS
C8166 M37GXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoHXTWM2OD1|NEWuN|M5KM7:TR?= NI\0XIpUSU6JRWK=

多くの細胞株試験データを見る場合、クリックしてください

体内試験 Administration of MG-132 effectively rescues the expression levels and plasma membrane localization of dystrophin, β-dystroglycan, α-bdystroglycan, and α-sarcoglycan in skeletal muscle fibers from mdx mice, reduces muscle membrane damage, and ameliorates the histopathological signs of muscular dystrophy. [7] MG-132 treatment significantly reduces immobilization-induced skeletal muscle atrophy in mice, by downregulating the muscle-specific ubiquitin ligases atrogin-1/MAFbx and MuRF-1 mRNA. [8]

お薦めの試験操作(参考用のみ)

キナーゼ試験:

[1]

+ 展開

Measurement of inhibitory activities of MG-132 against 20S proteasome:

The reaction mixture for the 20S proteasome inhibitory assay contains 0.1 M Tris-acetate, pH 7.0, 20S proteasome, MG-132, and 25 μM substrate dissolved in dimethyl sulfoxide in a final volume of 1 mL. After incuba tion at 37 °C for 15 minutes, the reaction is stopped by the addition of 0.1 mL of 10% SDS and 0.9 mL of 0.1M Tris acetate, pH 9.0. The fluorescence of the reaction products is measured. To determine the IC50 against 20S proteasome, various concentrations of MG-132 are included in the assay mixture.
細胞試験:

[3]

+ 展開
  • 細胞株: KIM-2, HC11, and ES
  • 濃度: Dissolved in DMSO, final concentrations ~25 μM
  • 反応時間: 24, and 48 hours
  • 実験の流れ:

    Cells are exposed to various concentrations of MG-132 for 24, and 48 hours. Supernatant and monolayer cells are harvested by centrifugation and fixed in 70% ethanol in PBS for staining with acridine orange. Equal volumes of cells and acridine orange (5 mg/mL in PBS) are mixed on a microscope slide and examined by fluorescence microscopy. For annexin V analysis, cells are harvested by centrifugation and stained with annexin V and propidium iodide. For cell cycle analysis, cells are rehydrated in PBS at room temperature for 10 minutes, followed by staining with propidium iodide (5 mg/mL). All samples are analyzed using a Coulter Epics XL flow cytometer.


    (参考用のみ)
動物試験:

[7]

+ 展開
  • 動物モデル: Male mdx (C57BL/10ScSn DMD mdx) mice
  • 製剤: Dissolved in DMSO, and diluted in PBS
  • 投薬量: ~10 μg/kg/day
  • 投与方法: Injection
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 90 mg/mL (189.22 mM)
Ethanol 25 mg/mL (52.56 mM)
Water Insoluble
体内 順序で溶剤を入れること:
4% DMSO+30% PEG 300+20% propylene glycol+ddH2O
2mg/mL

* 溶解度検測はSelleck技術部門によって行いますので、文献より提供された溶解度と差異がある可能性がありますが、生産工芸と不同ロット(lot)で起きる正常な現象ですから、ご安心ください。

化学情報

分子量 475.62
化学式

C26H41N3O5

CAS No. 133407-82-6
保管
in solvent
別名 N/A

便利ツール

モル濃度計算器

モル濃度計算器

解決のために必要とされるマス、ボリュームまたは濃度を計算してください。

マス (g) = 濃度 (mol/L) x ボリューム (L) x 分子量 (g/mol)

モル濃度計算器方程式

  • マス
    濃度
    ボリューム
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備することを要求される希釈剤を計算してください. セレック希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 輸入 輸出 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

マス 濃度 ボリューム 分子量

技術サポート

ストックの作り方、阻害剤の保管する方法、細胞実験や動物実験に注意すべきな点を全部含めており、製品を取扱う時よくあった質問に対して取扱説明書でお答えいたします。

Handling Instructions

他の質問がある場合は、お気軽くお問合せください。

  • * 必須

よくある質問(FAQ)

  • 問題1:

    I want to know whether it contains EDTA or other chelating agent in this product(S2619)?

  • 回答:

    Our S2619 MG-132 doesn't contain EDTA or other chelating agent.

Proteasome信号経路図

Proteasome Inhibitors with Unique Features

相関Proteasome製品

Tags: MG-132を買う | MG-132 ic50 | MG-132供給者 | MG-132を購入する | MG-132費用 | MG-132生産者 | オーダーMG-132 | MG-132化学構造 | MG-132分子量 | MG-132代理店
×
細胞株 試験類型 濃度 培養時間 溶剤類型 活性叙述 PMID