MG-132

製品コードS2619

MG-132化学構造

分子量(MW):475.62

MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.

サイズ 価格(税別)  
JPY 8300.00
JPY 28220.00
JPY 78020.00

Selleckは効果が一番いいである(S,R,S)-(-)-2のコンフィギュレーションを採用しましたので、MG-132プロテアソームの抑制効果はSigmaの同類製品の効果より著しく高くなります

正常には、p21蛋白はユビキチン化で分解されますが、MG-132はプロテアソームの活性を抑制することを通じて、p21蛋白の貯まりを引き起こします。だから、MG-132の抑制効果は強ければ強いほど、p21蛋白の貯まりは多くなってきます。(検査された蛋白:p21  細胞株:HeLa细胞株 処理条件:濃度5μM 処理時間:6h)

文献中の使用例(47)

カスタマーフィードバック(10)

  • MDA-MB-231 cells were treated with 10 uM MG132 and incubated under normoxia or hypoxia for 4 h. Endogenous interaction between LATS2 and SIAH2 was analysed by immunoprecipitation.

    Nat Cell Biol 2015 17(1), 95-103. MG-132 purchased from Selleck.

    HeLa cells were transfected with control mimic, RMND5A siRNA or miR-138 mimic. After transfection for 36 h, cells were treated with proteasome inhibitor MG132 (20 uM) or Dimethyl sulfoxide (DMSO) for 8 h. Endogenous Exportin-5 protein and RMND5A protein expression was measured by western blotting.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

  • HeLa cells were transfected with negative control mimic, miR-138 mimic or RMND5A siRNA. After transfection for 36 h, cells were treated with MG132 (20 uM) or DMSO for 8 h. RMND5A and Exportin-5 protein expression were analyzed by immunocytochemistry. Nuclei were counterstained with DAPI.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

     

    TFEB induced autophagy dependent ATZ clearance in vitro. MEF transiently co-transfected with either ATZ plus GFP expressing plasmids or ATZ plus TFEB expressing plasmids were incubated with proteasome inhibitor MG132 or with DMSO for 6 h. Upon MG132 treatment, steady state levels of 52 kDa ATZ band increased in both cells transfected with ATZ plus GFP and with ATZ plus TFEB expressing plasmids. Quantification of band intensities showed a 48% reduction of ATZ in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP, in the absence of the proteasome inhibitor. In MG132 treated cells, a 61% decrease of ATZ was detected in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP.

    EMBO Mol Med 2013 5, 397-412. MG-132 purchased from Selleck.

  • JAK1 expression was analyzed in A375 cells expressing scrambled shRNA or shRNF125 (#2) and treated with MG132 (5 uM, 10 hr), and in Lu1205 cells expressing WT RNF125 and treated with MG132.

    Cell Rep 2015 11(9), 1458-73. MG-132 purchased from Selleck.

    LRB1 and LRB2 regulate phyB protein levels. PhyB protein levels in crude extracts from the wild type (WT) and the indicated mutant backgrounds were assayed by immunoblot analysis with anti-phyB monoclonal antibodies. Anti-PBA1 and anti-histone H3 antibodies were used to confirm equal protein loading. Rc-induced loss of phyB in the wild type is inhibited by 100 uM MG132.

    Plant Physiol 2012 60(1), 118-34. MG-132 purchased from Selleck.

  • Representative images for γ-H2AX-stained cells treated with 100 uM FA for 3 h without or with MG132. Fluorescence was measured in at least 50 nuclei in each of three experiments.

    Toxicol Appl Pharmacol 2015 286(2), 135-41. MG-132 purchased from Selleck.

    GSK-3β phosphorylation at Ser9 is enhanced in NOK-overexpressed stable cell lines. The proteasome inhibitor, MG132, was added in medium of HeLa-HA and HeLa-NOK-HA cells for 12 h and then the p-GSK-3b(Ser9) was assayed by western blotting.

    FEBS Lett 2012 586, 3787–3792. MG-132 purchased from Selleck.

  • Nek2A impedes SuFu ubiquitination. HEK293T cells transfected with Nek2A-Myc and Flag-SuFu for 48 h were treated with MG-132 to enrich ubiquitinated proteins, and subsequently subjected to co-immunoprecipitation assay. Precipitated proteins were probed using anti-Ub antibody.

    Int J Oncol, 2017, 50(2):373-380. MG-132 purchased from Selleck.

    Truncated mouse Period2 (Per2) protein was expressed in NIH3T3 cells, treated by cycloheximide with or without MG132 for 1-4 hours.Per2 was reported to be degraded by the proteasome proteolysis. By adding MG132 (25 μM), a proteasome inhibitor, the degradation of Per2 was dramatically decreased within 4 hours treatment (shown by western blot).

    2012 Dr. Edison DUKE-NUS Graduate Medical School Singapore.. MG-132 purchased from Selleck.

質量管理及び製品安全説明書

Proteasome阻害剤の選択性比較

生物活性

製品説明 MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.
ターゲット
20S proteasome [9]
(Cell-free assay)
100 nM
体外試験

MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM. MG-132 also inhibits calpain with IC50 of 1.2 μM. MG-132 induces neurite outgrowth in PC12 cells at an optimal concentration of 20 nM, displaying 500 times more potency than ZLLal. [1] MG-132 (10 μM) potently inhibits TNF-α-induced NF-κB activation, interleukin-8 (IL-8) gene transcription, and IL-8 protein release in A549 cells by inhibition of proteasome-mediated IκBα degradation. [2] MG-132 treatment potently induces p53-dependent apoptosis in KIM-2 cells by 26S proteasome inhibition. [3] Unlike BzLLLCOCHO or PS-341, MG-132 treatment results in weak inhibition of the chymotrypsinlike (CT-L) and peptidylglutamyl peptide hydrolysing (PGPH) activities of the 26S proteasome, whereas multiple myeloma cells (U266 and OPM-2) are more sensitive to induction of apoptosis by MG-132 than BzLLLCOCHO. [4] MG-132 (1 μM) sensitizes TRAIL-resistant prostate cancer cells by activating the AP-1 family members c-Fos and c-Jun, which, in turn, repress the antiapoptotic molecule c-FLIP(L). [5] MG-132 significantly enhances the ability of inositol hexakisphosphate (IP6) to reduce cellular metabolic activity in both PC3 and DU145 androgen-independent prostate cancer (AIPCa) cell lines. [6]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
LPS-stimulated RAW264.7 cells MVzGeY5kfGmxbjDBd5NigQ>? MXuyOUDPxE1? M{XD[2ROW09? MojxTY5pcWKrdIOgcol1emmlIH;4bYRmKHC{b3T1Z5Rqd25id3n0bEBKSzVyIH;mJFAvOSEQvF2= NFPYWW4zPDZ7N{S5Oi=>
HL-60 M{i5TGN6fG:2b4jpZ{BCe3OjeR?= MYO0NEDPxE1? M{jVfVQ5KGh? MWHEUXNQ M1Pn[GlEPTB:MUCg{txO MmHLNlQ3QTd2OU[=
SMMC-7721 MljFR5l1d3SxeHnjJGF{e2G7 MVS0NEDPxE1? MXu0PEBp NGrNPHRFVVOR MnrKTWM2OD15LkGg{txO M2T5VlI1Pjl5NEm2
A-549 M1vNcWN6fG:2b4jpZ{BCe3OjeR?= M{PVclQxKM7:TR?= MoTJOFghcA>? Mm[0SG1UVw>? M3HFcmlEPTB:MUCg{txO M{PvblI1Pjl5NEm2
MCF-7 M1;GTmN6fG:2b4jpZ{BCe3OjeR?= NGjYVGc1OCEQvF2= MWm0PEBp MVrEUXNQ NHG2UZJKSzVyPUeuN{DPxE1? NFfJfYYzPDZ7N{S5Oi=>
SW-480 NH3nW3ZEgXSxdH;4bYMhSXO|YYm= MlriOFAh|ryP NYTPSodKPDhiaB?= MlfiSG1UVw>? NVjoZXVtUUN3ME20JO69VQ>? NX;I[FlXOjR4OUe0PVY>
NCI-H929 NF;I[XhEgXSxdH;4bYMhSXO|YYm= NFPvPZEyKM7:TR?= NIXGSm84OiCq MYnEUXNQ MnrQTWM2OD1yLkG3JO69VQ>? NXH5dI1xOjR4MkWwPFg>
293T NUe2SZFFS3m2b4TvfIlkKEG|c3H5 MYmxNEDPxE1? NVnoe2dDPzJiaB?= NUjkS2JCTE2VTx?= NV7tPGl5UUN3MEyyJO69VQ>? NHnFUnIzPDZ{NUC4PC=>
293T Ml;wSpVv[3Srb36gRZN{[Xl? NETrUJkyOCEQvF2= NVLaT4NDOjRiaB?= MXHEUXNQ NUWyTWdHVW:mZYLheIVtgSCrbnT1Z4V{KGinYYStd4hw[2tiIB?= NE\WN5MzPDZ{NUC4PC=>
HeLa Mn61T4lv[XOnIFHzd4F6 MnHsNVAh|ryP NV2wS2dqOSCq MmHQSG1UVw>? NYDqPJNpUW6mdXPld{BRSVKSIHPs[YF3[WenIHL5JIlvcGmkaYTpcocheHKxc3Xhd49u\SCjY4Tpeol1gQ>? MWqyOFMzOTh|Mx?=
MDA-MB-231 M{\rXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWexJO69VQ>? MX[3NkBp MYXEUXNQ Ml7WTWM2OD1yLkG4JO69VQ>? Mm\5NlQyPTN{ME[=
MCF-7 Ml7VS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVPn[W45OSEQvF2= M2OzfFczKGh? NUXJfI9OTE2VTx?= MUnJR|UxRTBwMUOg{txO MW[yOFE2OzJyNh?=
MCF10A NGDJV2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HEV|Eh|ryP MWm3NkBp NGDUdFZFVVOR NWXK[nFQUUN3ME2wMlI6KM7:TR?= M1;sXlI1OTV|MkC2
HEK-293 MXvLbY5ie2ViQYPzZZk> NEDhdGgzKGGwZDCyNEDPxE1? NIizfI0zKGh? NHe5bpNFVVOR MmjGTY5pcWKrdIOgR4hVNUxiYXP0bZZqfHlid3n0bEBKSzVyIH;mJFkhdk1i MoC4NlM2PDB5OUC=
Calu6 MWXGeY5kfGmxbjDBd5NigQ>? NXOzfHN4OTBizszN M4rYR|E5KGh? NVnFOXZ2TE2VTx?= NFrWOlBUcWewaX\pZ4FvfGy7IHHjZ5VufWyjdHXzJIZz[XSjeHnuJJBz\WO3coPvdi=> NEP2clkzOzVyNkS4Oi=>
IFN-gamma-induced RAW264.7 Mn\YSpVv[3Srb36gRZN{[Xl? NYfEVHk5TE2VTx?= NH3QdIpKdmirYnn0d{BvcXS{aXOgc5hq\GVicILv[JVkfGmxbjD3bZRpKEmFNUCgc4YhOC5yN{eg{txO NHXU[ngzOjJ5N{K3Oy=>
IPC227F MojiR5l1d3SxeHnjJGF{e2G7 MonPNUDPxE1? M4riNlQ5KGh? NUfwRmx7TE2VTx?= NUWyTIdIUUN3ME2wMlA4PyEQvF2= M1rOdlIyQTJ2NUK4
Hepa-1c1c7 MW\GeY5kfGmxbjDBd5NigQ>? MnPPNlUh|ryP MlHJOkBp MW\EUXNQ MlvnTY5kemWjc3XzJG5z\jJicILveIVqdiCuZY\lcC=> NHzL[oEzODN7MkW0OC=>
COS-7 NWj5NohvS3m2b4TvfIlkKEG|c3H5 MoLRNVAh|ryP NXrueVA1TE2VTx?= MX\JR|UxRDFyIN88US=> MW[xPFA5QDB7Nx?=
HuH-7 NUDFTGh3S3m2b4TvfIlkKEG|c3H5 Mn2zNVAh|ryP NXXzVmIxTE2VTx?= MnzXTWM2ODxzMDFOwG0> NI\sPWYyQDB6OEC5Oy=>
OCI-Ly3 NHjQTIJHfW6ldHnvckBCe3OjeR?= NIfFUnoyOCEQvF5CpC=> NI\6N3E1KGh? M{PnXWROW09? NVvpUpZwUW6mdXPld{BpfW2jbjDJb4FxeGGEYXzwbIEhe3SjYnnsbZpifGmxbjD3bZRpKEWFNUCgc4YhOSEQvF2= NV3sNpVDOThyMkSxNVM>
A2780 cDDP NFLZSXVCeG:ydH;zbZMhSXO|YYm= NWS4U3ZnOjRiaB?= NHnmSJFFVVOR MXjJcoR2[2W|IHHwc5B1d3OrczDifUBqdmirYnn0bY5oKFCWRV6g[IVoemGmYYTpc44> Mlm2NVc3QDRyMUi=
LPS-stimulated RAW264.7 cells MYfGeY5kfGmxbjDBd5NigQ>? M{[wRWROW09? NF3hNmtKdmirYnn0d{BPTi2tYYDwZWIhTE6DIHLpcoRqdmd? NHizVmQyPzRyN{K3Oy=>
PC12 MnvsSpVv[3Srb36gRZN{[Xl? NWTFPWo5OTByIN88UeKh Ml\CNlQhcA>? MWHEUXNQ NWTxUXJyUW6qaXLpeJMhPi2RSFTBMUBidmRiSELPNk1qdmS3Y3XkJIN6fG:2b4jpZ4l1gQ>? NFTIeWkyPzF3OES1OC=>
PC3 M{HI[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1HJblIxKM7:TR?= MlvrOFghcA>? M4OxU2ROW09? NWrzbINyUUN3ME2wMlYh|ryP MkTzNVY3QDZ3M{e=
LP-1 NHXYW2ZCeG:ydH;zbZMhSXO|YYm= MYmzNFAhdk1? MlS5NlQhcA>? NEXpPHNFVVOR NXK4XYZEUW6mdXPld{BieG:ydH;zbZMh[nliaX7jdoVie2mwZzDjcIVifmWmIGDBVnAhdGW4ZXygZY5lKHKnZIXjbY5oKE2lbD2xJJBzd3SnaX6gcIV3\Wx? MX2xOVk2QDV6OR?=
ES6 MlTCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HWWmlEPTB;MD6wNVMxPiEQvF2= M2fLWHNCVkeHUh?=
A101D NUnlcIZWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlG4TWM2OD1yLkCzNlc6KM7:TR?= NHPaUJNUSU6JRWK=
OCUB-M M3H0PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYPn[5B6UUN3ME2wMlA{PzN5IN88US=> NUjUco45W0GQR1XS
LB2518-MEL MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnMWVM{UUN3ME2wMlA{PzZizszN MlzJV2FPT0WU
SH-4 NUnvOmhCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVHJNmFmUUN3ME2wMlA1OzFizszN Mo[zV2FPT0WU
KNS-42 MlrOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYLFWndMUUN3ME2wMlA1PDRzIN88US=> MX\TRW5ITVJ?
DSH1 M4PP[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TXXWlEPTB;MD6wOVI5QSEQvF2= NIe5b2RUSU6JRWK=
NTERA-S-cl-D1 NYL4eINVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVT5fVV5UUN3ME2wMlA2Pzd{IN88US=> M2nGXnNCVkeHUh?=
D-542MG NVzX[Hc1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnjXTWM2OD1yLkC1PVU4KM7:TR?= Mn[4V2FPT0WU
KS-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHXLdmJKSzVyPUCuNFY1PThizszN Ml3qV2FPT0WU
BL-41 NWrKSmpLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXPJR|UxRTBwME[5OFch|ryP M1\JRnNCVkeHUh?=
LXF-289 M3\acWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWLJR|UxRTBwMEewOlYh|ryP Mn\QV2FPT0WU
D-247MG NH7pWZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVPRPFdRUUN3ME2wMlA4OjB7IN88US=> MXPTRW5ITVJ?
MMAC-SF NF;iXpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV7TeodQUUN3ME2wMlA4OjZ6IN88US=> NUjZNnY2W0GQR1XS
CP66-MEL NYnaZ2NkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPKb4dKSzVyPUCuNFc2KM7:TR?= NWfwdnVJW0GQR1XS
LB771-HNC NX7xN4JtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrDeZNuUUN3ME2wMlA5ODN4IN88US=> M3vaR3NCVkeHUh?=
no-10 NUTX[GpIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTBwMEi5NFkh|ryP MXXTRW5ITVJ?
A388 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTBwMEmwOlUh|ryP M3eyNnNCVkeHUh?=
OPM-2 NV7MfpVyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoLkTWM2OD1yLkGwOFc1KM7:TR?= M1zl[XNCVkeHUh?=
OVCAR-4 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjuTWM2OD1yLkGwPVM5KM7:TR?= NUTsNJlpW0GQR1XS
HOP-62 NWDyZVdvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTBwMUC5OFkh|ryP M4nuVHNCVkeHUh?=
ML-2 NXHQRYVrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGXtVYFKSzVyPUCuNVE5ODZizszN MnnkV2FPT0WU
UACC-257 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTBwMUG5Nlch|ryP MYnTRW5ITVJ?
NEC8 NU[zNoI4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTBwMUG5PVUh|ryP NF\xPIxUSU6JRWK=
ONS-76 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3TmdGlEPTB;MD6xNlk{PSEQvF2= M1fsSHNCVkeHUh?=
KE-37 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4S2e2lEPTB;MD6xN|I4QCEQvF2= M4rCV3NCVkeHUh?=
HT-144 MnL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTBwMUO4PVUh|ryP MVLTRW5ITVJ?
LB2241-RCC NX7PSWd[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXfydlg1UUN3ME2wMlE1OjR5IN88US=> MmO5V2FPT0WU
TE-5 MnXyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHH1TZBKSzVyPUCuNVQzPzhizszN M4\ydHNCVkeHUh?=
KINGS-1 M{\3OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWDzfmF5UUN3ME2wMlE1PzlizszN Moq4V2FPT0WU
NCI-H69 M4jGSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYnJR|UxRTBwMUWxOFEh|ryP NYjSS|dVW0GQR1XS
CAS-1 M{n0bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTBwMUW0PFIh|ryP MXzTRW5ITVJ?
D-263MG MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnLDTWM2OD1yLkG2NFA3KM7:TR?= MWHTRW5ITVJ?
A253 NXLVW5FqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE[0XlFKSzVyPUCuNVYyOjhizszN NF;4Uo5USU6JRWK=
PF-382 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTBwMU[3NFYh|ryP MV3TRW5ITVJ?
CESS M2PhXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1\oZ2lEPTB;MD6xO|A3KM7:TR?= MYHTRW5ITVJ?
MZ2-MEL M3rEUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1yyO2lEPTB;MD6xO|U2QSEQvF2= M2HWUXNCVkeHUh?=
HEL NHHKWFlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUDmc49[UUN3ME2wMlE5PTF5IN88US=> M{X5T3NCVkeHUh?=
D-392MG Mmf4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGG2ZWpKSzVyPUCuNVkyOTVizszN NUL4bZVNW0GQR1XS
SK-LMS-1 M{i0VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFexOXJKSzVyPUCuNVk{ODNizszN MXXTRW5ITVJ?
GI-ME-N MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk\jTWM2OD1yLkG5N|A3KM7:TR?= NYfMOlR3W0GQR1XS
LB831-BLC NFvGNopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vW[mlEPTB;MD6xPVM1KM7:TR?= MkHRV2FPT0WU
DU-4475 Mo\2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlK3TWM2OD1yLkG5OlU5KM7:TR?= M2j0e3NCVkeHUh?=
IST-SL1 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV;JR|UxRTBwMkCwPVQh|ryP NVHzSlFwW0GQR1XS
GAK Mn\qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HNO2lEPTB;MD6yNFU{PCEQvF2= NH:0[|lUSU6JRWK=
EW-1 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTBwMkGwOFch|ryP NHO5fnlUSU6JRWK=
LAMA-84 MmrwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWXqRZIyUUN3ME2wMlIyQDVzIN88US=> MYHTRW5ITVJ?
SK-UT-1 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUfQbJRYUUN3ME2wMlIzODR7IN88US=> NHLBXoxUSU6JRWK=
VA-ES-BJ MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1izOWlEPTB;MD6yNlI2PyEQvF2= NX[zbGlWW0GQR1XS
ACN M{jBfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2m2RWlEPTB;MD6yNlY{QCEQvF2= NE\5OFlUSU6JRWK=
SK-PN-DW MmLPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HXNmlEPTB;MD6yN|E6KM7:TR?= M{LxR3NCVkeHUh?=
HD-MY-Z MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfIS2VzUUN3ME2wMlI{OzB|IN88US=> NWrYPYZMW0GQR1XS
LB373-MEL-D M4XyeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIP5c21KSzVyPUCuNlQyQThizszN NV7FcIJLW0GQR1XS
COLO-829 M4K2RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorETWM2OD1yLkK0NlU4KM7:TR?= NEPnU3JUSU6JRWK=
ES8 NHz1ZXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHTUOoRKSzVyPUCuNlQ4PjNizszN MlzpV2FPT0WU
RXF393 M3rvXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;STWM2OD1yLkK1NFE2KM7:TR?= MYDTRW5ITVJ?
TK10 MlPKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnXTpZ1UUN3ME2wMlI2PDN3IN88US=> NGG3PYlUSU6JRWK=
LOUCY M1;iT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3MV|VoUUN3ME2wMlI2PDV4IN88US=> NXvvTXBEW0GQR1XS
MZ7-mel NYHzdFhNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFy1[3ZKSzVyPUCuNlY{PzRizszN NF;uTWRUSU6JRWK=
CP67-MEL NU\rd|dET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXfJR|UxRTBwMk[3N{DPxE1? MoDmV2FPT0WU
C2BBe1 NXrxRWlTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVLEWGEyUUN3ME2wMlI4QTB5IN88US=> M17zSXNCVkeHUh?=
K052 Mm\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;qdolKSzVyPUCuNlg6QSEQvF2= MY\TRW5ITVJ?
MOLT-16 M2f4[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTBwMkm1NlQh|ryP MYPTRW5ITVJ?
KNS-81-FD M37GVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHi3ZYJKSzVyPUCuN|A{OjNizszN NVf0[ldEW0GQR1XS
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LAN-6 NHu3TVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3G4S2lEPTB;MD6zNVMh|ryP NVLOb5RbW0GQR1XS
KLE MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MojtTWM2OD1yLkOxN|A3KM7:TR?= MUnTRW5ITVJ?
NCCIT MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NE\NV|ZKSzVyPUCuN|E4QDNizszN NU[1SnY{W0GQR1XS
HH MlXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHLNcG1KSzVyPUCuN|I5QTdizszN MYrTRW5ITVJ?
TE-8 NYfEfIk3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLBTWM2OD1yLkO0Nlc6KM7:TR?= NX3zeW9CW0GQR1XS
GDM-1 NWrqbY9rT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlvOTWM2OD1yLkO1NVA1KM7:TR?= M{f4[3NCVkeHUh?=
NCI-H747 NUHRVoFiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml3qTWM2OD1yLkO3NVA{KM7:TR?= NUTWSXg2W0GQR1XS
NCI-H1092 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjJTpdsUUN3ME2wMlM5QDR2IN88US=> MmnmV2FPT0WU
8-MG-BA NX;RR2xuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTBwM{m4N|ch|ryP MXnTRW5ITVJ?
NB17 NGfHWnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;ETWM2OD1yLkSyPVch|ryP MULTRW5ITVJ?
LC4-1 NX\NZZRpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVXJR|UxRTBwNEO2NFch|ryP NH\jZlFUSU6JRWK=
TE-1 MnvoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;oUXZKSzVyPUCuOFUyOTlizszN MkP3V2FPT0WU
KALS-1 NVrJbHBmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDRTWM2OD1yLkS2OVg1KM7:TR?= NWHN[4V5W0GQR1XS
CCRF-CEM NX25d5RPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{jiW2lEPTB;MD60O|Y4PCEQvF2= MUTTRW5ITVJ?
OS-RC-2 MoHyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUfaR5FXUUN3ME2wMlQ4QTd{IN88US=> MmLzV2FPT0WU
A704 M4PofGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnmcm01UUN3ME2wMlQ5Pjl{IN88US=> MnTtV2FPT0WU
BB49-HNC MoG4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXfJR|UxRTBwNEmwPVYh|ryP MW\TRW5ITVJ?
EVSA-T NF70UohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mom4TWM2OD1yLkS5PVEyKM7:TR?= NUXxb2VUW0GQR1XS
Mo-T M2HP[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXzJR|UxRTBwNUG3OlIh|ryP NYPZclJSW0GQR1XS
MONO-MAC-6 NEnRR2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUnJR|UxRTBwNUO2NVEh|ryP Mkj1V2FPT0WU
BB65-RCC MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIfhPYJKSzVyPUCuOVY5OTFizszN MV;TRW5ITVJ?
NCI-H1882 M4HOOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVLtcpZpUUN3ME2wMlU6ODN4IN88US=> MUTTRW5ITVJ?
TE-9 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTBwNkGwN|Mh|ryP NX6xOZM4W0GQR1XS
NCI-H2126 Mk\yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MonITWM2OD1yLk[yOlY6KM7:TR?= M3G2cnNCVkeHUh?=
SF268 Mm\HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTBwNkW2OFEh|ryP Mme2V2FPT0WU
SW872 NYe5Z2w6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;WSZhIUUN3ME2wMlY2PzJ7IN88US=> M4fjUnNCVkeHUh?=
LS-513 M3L6UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF;6XHdKSzVyPUCuOlY4PTFizszN MUjTRW5ITVJ?
NCI-H1355 NEXIdXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGnweHRKSzVyPUCuOlg3OTlizszN M4nqNHNCVkeHUh?=
BL-70 NYfMU2NOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnMTWM2OD1yLk[5N|g5KM7:TR?= M4nLSHNCVkeHUh?=
NCI-SNU-5 NX3QW5FWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn3VTWM2OD1yLk[5OVQ2KM7:TR?= MnvwV2FPT0WU
SNU-C2B MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mm[0TWM2OD1yLkewO|M6KM7:TR?= MY\TRW5ITVJ?
GB-1 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHfON|hKSzVyPUCuO|IyOjRizszN NHW5NGtUSU6JRWK=
CTB-1 NV[1dXdHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXjq[|NmUUN3ME2wMlc4QTV3IN88US=> NE\xWpZUSU6JRWK=
Becker M2jGc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\tWGhKSzVyPUCuO|k3OjFizszN Mon2V2FPT0WU
KM12 M4LFWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoP0TWM2OD1yLki1OFY3KM7:TR?= Mnr4V2FPT0WU
ES7 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7jZVF3UUN3ME2wMlg6PjVizszN NYPsPW5IW0GQR1XS
COLO-684 NUS4[WZqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfOTWM2OD1yLkmwOlU5KM7:TR?= M3zWcnNCVkeHUh?=
HCC2998 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlzmTWM2OD1yLkmzPFU1KM7:TR?= NYL5S5BMW0GQR1XS
TE-10 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTBwOU[0N{DPxE1? NETre25USU6JRWK=
SF126 MoHBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTBwOUi5O|Eh|ryP M{P5RnNCVkeHUh?=
EKVX Mn7NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYD5OHhOUUN3ME2xMlA{PDR{IN88US=> M1jnO3NCVkeHUh?=
KARPAS-45 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mm\GTWM2OD1zLkC0NFE3KM7:TR?= MWnTRW5ITVJ?
KGN NGfrTIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1LGbmlEPTB;MT6wOVA1PSEQvF2= M3fGRXNCVkeHUh?=
ES1 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHviXJhKSzVyPUGuNFc6OjFizszN NYrhcmtwW0GQR1XS
L-540 NFfLPFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3PTWM2OD1zLkGxPFM6KM7:TR?= MVrTRW5ITVJ?
KURAMOCHI NEXSdHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfzTWM2OD1zLkGyN|c1KM7:TR?= NYnxOlhjW0GQR1XS
LU-65 NUC4NYN5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnexTWM2OD1zLkGyO|U{KM7:TR?= MVHTRW5ITVJ?
MFH-ino NGnoTnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NET5NlVKSzVyPUGuNVc2ODFizszN NG\GbFBUSU6JRWK=
NCI-H23 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlf6TWM2OD1zLkKwOFEh|ryP NIfZcZBUSU6JRWK=
IA-LM NUDMfllHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGLSSm9KSzVyPUGuNlQyOTZizszN MorJV2FPT0WU
PSN1 M2LMcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2KydmlEPTB;MT6yO|AyPiEQvF2= NEjCeXZUSU6JRWK=
NCI-H719 M{\5cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTFwMke0NVEh|ryP NGLK[XRUSU6JRWK=
SW684 M4OxdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUKxb5o4UUN3ME2xMlI5PjV7IN88US=> MUDTRW5ITVJ?
HCE-4 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1vQS2lEPTB;MT6zNFIzOSEQvF2= MYDTRW5ITVJ?
EW-16 Mn3XS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmDwTWM2OD1zLkOxN|Q4KM7:TR?= MYHTRW5ITVJ?
NCI-H128 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTFwM{W4NVQh|ryP MnL5V2FPT0WU
HC-1 NVfPd|hXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTFwM{ixO{DPxE1? NIf4Z4VUSU6JRWK=
IST-MES1 NXmyVFhQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPaR3JKSzVyPUGuOFAzODhizszN MoDtV2FPT0WU
Raji MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfFb4ZyUUN3ME2xMlQyQDVizszN NI[4bHdUSU6JRWK=
DMS-114 NFLxR45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2jK[mlEPTB;MT60OFU{QSEQvF2= M{XuW3NCVkeHUh?=
GI-1 NYWwfYNGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEPNfFdKSzVyPUGuOFcyOzFizszN M3n4ZXNCVkeHUh?=
NCI-H2081 M4HVTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4PuemlEPTB;MT61OVE6PiEQvF2= MoLJV2FPT0WU
LC-1F NGPhdIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTFwNUWxPVgh|ryP MlmxV2FPT0WU
NCI-H2227 NEPwUVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXPTfJpPUUN3ME2xMlYyPTZzIN88US=> MYrTRW5ITVJ?
D-502MG M2fNZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2jCOWlEPTB;MT62O|IyOSEQvF2= M4GySnNCVkeHUh?=
NCI-H2141 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1jSNGlEPTB;MT62O|MyPyEQvF2= MVrTRW5ITVJ?
LS-411N NIf6Z41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFLnUpRKSzVyPUGuOlk5ODdizszN M3XmO3NCVkeHUh?=
SU-DHL-1 NVq2eJFRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmixTWM2OD1zLkexNlgyKM7:TR?= NFnYW3ZUSU6JRWK=
BB30-HNC Mn;BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoDqTWM2OD1zLkeyOlg2KM7:TR?= M4C0cXNCVkeHUh?=
TE-15 NXjqNVBlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTFwOUKzO|Mh|ryP Mn\xV2FPT0WU
JVM-3 NWnVb5A6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnufpZZUUN3ME2xMlk{QTB2IN88US=> M1Lqb3NCVkeHUh?=
IST-SL2 NE\UeHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTJwMEGyOVIh|ryP M1jWWXNCVkeHUh?=
EW-18 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHyTWM2OD1{LkCyN|M4KM7:TR?= Mm\JV2FPT0WU
DJM-1 NGTsVmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTJwMEK1OVIh|ryP NVPvUWJ4W0GQR1XS
no-11 NH3wcotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX\LeJJqUUN3ME2yMlA{OTB2IN88US=> NYHMfJNZW0GQR1XS
QIMR-WIL MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{Lqd2lEPTB;Mj6xOlc3OiEQvF2= NVTzTZZpW0GQR1XS
MC-CAR MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1vKW2lEPTB;Mj6yNlk2KM7:TR?= M3LLVHNCVkeHUh?=
KM-H2 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWqyUWNZUUN3ME2yMlI6ODR|IN88US=> M4e5eXNCVkeHUh?=
ECC12 MlTSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2G3SmlEPTB;Mj6zO|k1KM7:TR?= NFr5VW9USU6JRWK=
HCE-T NHnRbmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV7JR|UxRTJwNES4PFMh|ryP NInWW4pUSU6JRWK=
MFM-223 NVy1NW82T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUfJR|UxRTJwNUC4O|Eh|ryP NXzIOpEyW0GQR1XS
SW982 NV63TmVLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjkelV[UUN3ME2yMlUyPDhizszN M1zpd3NCVkeHUh?=
KG-1 Ml3oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUjxXGdSUUN3ME2yMlg5PzlzIN88US=> MlezV2FPT0WU
ES4 NX;kc4JsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjkWI5KSzVyPUOuNFYyOTFizszN MYHTRW5ITVJ?
SCC-3 MomwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYHHR|hjUUN3ME2zMlExQDR6IN88US=> MV7TRW5ITVJ?
RH-1 NUDkc49JT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrtTWM2OD1|LkO4O|Q5KM7:TR?= M1\Rb3NCVkeHUh?=
NCI-H748 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWn1XZZHUUN3ME2zMlQ1OjZ4IN88US=> MXXTRW5ITVJ?
HCC2218 MoD1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHTRNmlKSzVyPUOuOFY6OzdizszN NUXDNVREW0GQR1XS
MEG-01 M3vyWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{nXdGlEPTB;Mz61PVY5KM7:TR?= M{THNnNCVkeHUh?=
NB12 NU\PSIU1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MorkTWM2OD1|LkW5PFg5KM7:TR?= NX3wVY1RW0GQR1XS
SNB75 M4DsUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTNwNkCxNFMh|ryP MX7TRW5ITVJ?
KMS-12-PE NH;QSotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTNwNke3NlMh|ryP NVqzU20yW0GQR1XS
SKM-1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn73TWM2OD1|LkexN|c3KM7:TR?= NXzPeIM6W0GQR1XS
COLO-320-HSR MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2DET2lEPTB;Mz63OVY{PCEQvF2= MoPwV2FPT0WU
NKM-1 NXLV[oZGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2S2SGlEPTB;Mz63O|M4QCEQvF2= NX\Zd5NbW0GQR1XS
TE-6 NYTLblNnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmHITWM2OD1|Lkm0OVYyKM7:TR?= NUnjdWVKW0GQR1XS
D-336MG MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkLwTWM2OD12LkCxNVY3KM7:TR?= MkWwV2FPT0WU
NCI-H1650 NWXN[IJ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfWeG43UUN3ME20MlE2Pzl5IN88US=> MnXNV2FPT0WU
ES3 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTRwM{K4NlQh|ryP M3\ZcnNCVkeHUh?=
YT M1TycGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnjQTWM2OD12LkO1OFI1KM7:TR?= M{HabHNCVkeHUh?=
ES5 NGLMTWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX3JR|UxRTRwNECyOVUh|ryP MnfhV2FPT0WU
LB647-SCLC MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXnJR|UxRTRwNU[zNFgh|ryP M3X6cnNCVkeHUh?=
HAL-01 MlfzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLWTWM2OD12LkW3NFM1KM7:TR?= MX;TRW5ITVJ?
LP-1 NWfD[JBNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHK2UIpKSzVyPUSuO|I{PzFizszN M2jx[HNCVkeHUh?=
BC-1 M{nMTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXXhUGFsUUN3ME21MlAxPDR5IN88US=> NGD4b5lUSU6JRWK=
EB-3 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2HvSWlEPTB;NT6wN|A1OSEQvF2= NW\lOoZkW0GQR1XS
GT3TKB MmfDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HBWWlEPTB;NT6xO|Y3OiEQvF2= NYLrWo1bW0GQR1XS
NCI-H209 NIHmcZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn6xTWM2OD13LkG5N|UzKM7:TR?= M3z6[nNCVkeHUh?=
BT-474 NHPVWJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmK3TWM2OD13LkKzNVAzKM7:TR?= Mof6V2FPT0WU
RKO NX24foZ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzFNHBKSzVyPUWuNlM1OjJizszN MnjtV2FPT0WU
SIMA Mnv1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnlTWM2OD13LkOwO|Y2KM7:TR?= MlXJV2FPT0WU
RL M1Lqe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFv4ZnpKSzVyPUWuN|c2PDFizszN MYrTRW5ITVJ?
GCIY MlT5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWPoUnQ6UUN3ME21MlQ4OjN4IN88US=> NVOxUlhwW0GQR1XS
Calu-6 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnfRTWM2OD13Lk[yNkDPxE1? MYDTRW5ITVJ?
ALL-PO M1vWTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mmj3TWM2OD13Lk[zO|k2KM7:TR?= NXjTcVNlW0GQR1XS
ARH-77 NXXmU3ZlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGOxR21KSzVyPUWuOlcxQDdizszN MYfTRW5ITVJ?
A4-Fuk Mn64S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInNeGdKSzVyPU[uNFgyOThizszN M2rt[nNCVkeHUh?=
NCI-H1581 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLEXpI4UUN3ME22MlI{QDR7IN88US=> MlvJV2FPT0WU
HUTU-80 NWn2d2RRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MonITWM2OD14LkO2PFk4KM7:TR?= Mn65V2FPT0WU
TGW M{HOZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkO2TWM2OD14LkS1OVk{KM7:TR?= NY[2eZd{W0GQR1XS
SK-N-FI NHq4cXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTZwNEW4OVQh|ryP MVjTRW5ITVJ?
U-266 Mlz6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2PyVWlEPTB;Nj61NVkzPiEQvF2= M13TVXNCVkeHUh?=
EM-2 NXfKbGo2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTZwNkewPVkh|ryP NUjuUXo6W0GQR1XS
NMC-G1 NFfLOVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF\2PIFKSzVyPU[uO|E5QTVizszN NUjK[|hiW0GQR1XS
KASUMI-1 Mlz3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUjJR|UxRTZwOES3PFch|ryP M4ntSXNCVkeHUh?=
NALM-6 NVq2TJp[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIDaZ2dKSzVyPU[uPFY4PTRizszN MWTTRW5ITVJ?
OCI-AML2 NGS3T5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYTJR|UxRTdwMECzNlYh|ryP MmX0V2FPT0WU
SHP-77 NUTiUWpPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NETNPFdKSzVyPUeuNlI1OyEQvF2= NYPBSFBGW0GQR1XS
NOMO-1 Mo\QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTdwMkSyOVQh|ryP NWi5Tno3W0GQR1XS
SK-N-DZ NFnWemlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\iTWM2OD15LkexNFg6KM7:TR?= MlGzV2FPT0WU
LB1047-RCC MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zh[WlEPTB;Nz63NlI{OSEQvF2= MkG3V2FPT0WU
MZ1-PC MnzWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TjS2lEPTB;Nz64OlU2QCEQvF2= NYfVepZUW0GQR1XS
NB10 NGjPfZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV7EPJpjUUN3ME23Mlk6PTV4IN88US=> MX3TRW5ITVJ?
RL95-2 M{P6dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWjJR|UxRThwMUC4OFIh|ryP MVLTRW5ITVJ?
OMC-1 M33ybWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRThwNUKxPVEh|ryP MWHTRW5ITVJ?
D-283MED NEXiUXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHzTUYpKSzVyPUiuPVE4OTlizszN Ml[yV2FPT0WU
MC116 MmDYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIS3Z2tKSzVyPUiuPVc6PCEQvF2= M{TP[XNCVkeHUh?=
SJSA-1 MlfDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfkc2VnUUN3ME25MlA6ODlzIN88US=> MVnTRW5ITVJ?
JiyoyeP-2003 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGHvUoNKSzVyPUmuNlk{OTdizszN MWHTRW5ITVJ?
IST-MEL1 NFnQOFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3HSHhUUUN3ME25Mlc1OTl6IN88US=> MUDTRW5ITVJ?
CTV-1 M4[yc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7wellKSzVyPUGwMlA6PzlizszN MYDTRW5ITVJ?
NH-12 NHf4TmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2rGUmlEPTB;MUCuNlQ{OyEQvF2= NUS5PYxNW0GQR1XS
CA46 MmPsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojjTWM2OD1zMD6zOlEh|ryP MYXTRW5ITVJ?
NCI-SNU-1 MnvxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGWycnFKSzVyPUGwMlQ6PjlizszN NEfWe4NUSU6JRWK=
SCLC-21H NEXKclBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4XadmlEPTB;MUCuOlU6PiEQvF2= NWjiNJNEW0GQR1XS
EC-GI-10 Mm[zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWXJR|UxRTFyLkewN|Eh|ryP MWLTRW5ITVJ?
SR MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjRTWM2OD1zMT6wNVg2KM7:TR?= NFj2TodUSU6JRWK=
NCI-H1648 NX\QOld7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxRTFzLkC5OlUh|ryP M4ftbHNCVkeHUh?=
TGBC1TKB MlXjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIqzTVJKSzVyPUGxMlQyODJizszN NFLJR|FUSU6JRWK=
EW-11 MkWwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGf3OmVKSzVyPUGxMlUyQDZizszN M2O2[3NCVkeHUh?=
SK-MM-2 MoXHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUXJR|UxRTFzLkiwOlEh|ryP MmrVV2FPT0WU
NCI-H524 NWrhWlVZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1ftNmlEPTB;MUGuPVgzOiEQvF2= MkHrV2FPT0WU
NOS-1 MoL4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1zJWGlEPTB;MUKuNFM1PSEQvF2= MV;TRW5ITVJ?
AM-38 MonJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFewW3pKSzVyPUGyMlU3OzNizszN MkPkV2FPT0WU
A498 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2LQWWlEPTB;MUKuO|A3QSEQvF2= NHjFZ2RUSU6JRWK=
KARPAS-422 MkHuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTF{Lke0PVYh|ryP MnrtV2FPT0WU
LU-139 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFr4VWZKSzVyPUGyMlkxOjZizszN M2TWS3NCVkeHUh?=
COR-L88 NXv2RlJjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFPC[ZdKSzVyPUGyMlk{QDJizszN MkPRV2FPT0WU
K5 NXexSIpzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rQdmlEPTB;MUKuPVQ3OiEQvF2= MXPTRW5ITVJ?
NB13 MmHWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfpcmJtUUN3ME2xNk46Pzh|IN88US=> M2WzdXNCVkeHUh?=
MRK-nu-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYG4cnpHUUN3ME2xN{4yQTVizszN M{\jSXNCVkeHUh?=
MHH-NB-11 NEXlR49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX23VmROUUN3ME2xN{4zQTB{IN88US=> NFzSNplUSU6JRWK=
KU812 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWW2eG5[UUN3ME2xN{43OTJ2IN88US=> NV7RV5k5W0GQR1XS
TE-12 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2L2e2lEPTB;MUOuOlk6PCEQvF2= NEKxbFVUSU6JRWK=
NCI-N87 M4fYXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWL4U44yUUN3ME2xN{44OzZizszN MXfTRW5ITVJ?
EB2 Mne1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWf0dppMUUN3ME2xN{45PTB3IN88US=> NETqPHFUSU6JRWK=
DB MoWwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3n1eGlEPTB;MUOuPVg5PSEQvF2= M13lbHNCVkeHUh?=
697 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYjiWFloUUN3ME2xOE41PTFzIN88US=> MUnTRW5ITVJ?
MSTO-211H NHS5c4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEPT[2tKSzVyPUG0Mlc1PDhizszN NFzpR3RUSU6JRWK=
JVM-2 NGjBWWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYTJR|UxRTF2Lke3N|Uh|ryP M{Tn[3NCVkeHUh?=
COLO-824 NUnvPW9kT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHX1PIhKSzVyPUG0Mlc6QTRizszN MmnKV2FPT0WU
BC-3 NX;2NIRRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWfJR|UxRTF3LkO5PEDPxE1? MUfTRW5ITVJ?
BOKU M4nUWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPi[Gl7UUN3ME2xOU46PjB6IN88US=> NWnTSpZbW0GQR1XS
GOTO NFPnVnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX\OV|ZyUUN3ME2xOk46PjF5IN88US=> MXrTRW5ITVJ?
HCC2157 NX3ObnJbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGTiWYJKSzVyPUG3MlQ4PTVizszN MVzTRW5ITVJ?
LS-1034 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlXUTWM2OD1zNz62PFE5KM7:TR?= MlewV2FPT0WU
CAL-148 NEHJRWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1;2c2lEPTB;MUeuPVc6PiEQvF2= NFTDWmhUSU6JRWK=
MOLT-4 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX61Zmp3UUN3ME2xPE45OjB6IN88US=> MkD6V2FPT0WU
Daudi NV\DUFZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3EU|NtUUN3ME2xPE46OjNzIN88US=> MWjTRW5ITVJ?
J-RT3-T3-5 NIjvZZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVHab3lRUUN3ME2xPU41ODZ4IN88US=> MVXTRW5ITVJ?
KMOE-2 NIG2XYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWOwT4RNUUN3ME2xPU43PDh{IN88US=> MULTRW5ITVJ?
HL-60 NFnBbldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkiwTWM2OD1{MD6xPVY2KM7:TR?= M17STnNCVkeHUh?=
P31-FUJ M1zmSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LyV2lEPTB;MkCuOFc2OyEQvF2= MmnqV2FPT0WU
IM-9 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkLmTWM2OD1{MD62NlI1KM7:TR?= M3zsSXNCVkeHUh?=
HDLM-2 NWrUR21OT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHJTWM2OD1{MD64PFIyKM7:TR?= MXfTRW5ITVJ?
NCI-H1304 NXfmbJloT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTJzLkCzNVEh|ryP MXvTRW5ITVJ?
NCI-H345 Mn7SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\5TWM2OD1{MT6wOlQ{KM7:TR?= MWPTRW5ITVJ?
RPMI-6666 NFnhfG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TNc2lEPTB;MkGuN|YxOiEQvF2= M32yfnNCVkeHUh?=
GR-ST M{\1eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TIZWlEPTB;MkGuOFE4KM7:TR?= NGLLRpRUSU6JRWK=
CHP-126 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYDqV4hzUUN3ME2yNU43OThzIN88US=> Mn;rV2FPT0WU
EHEB M17yTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTJzLk[3N|Eh|ryP M2S5TXNCVkeHUh?=
CPC-N NIDxfVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDCTWM2OD1{ND6wNlAyKM7:TR?= MULTRW5ITVJ?
NB1 NI[4VlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF7aZYNKSzVyPUK0MlY6OzlizszN MnrzV2FPT0WU
LS-123 NVrwXGxtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MluxTWM2OD1{ND65NFEzKM7:TR?= NF;aUoRUSU6JRWK=
ST486 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2PvVmlEPTB;MkWuNVEyOyEQvF2= NV\yU443W0GQR1XS
NCI-H1963 NFPrW3dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFPubWxKSzVyPUK2MlA3OjNizszN MYHTRW5ITVJ?
U-87-MG MmPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1;Vb2lEPTB;Mk[uO|Y1PCEQvF2= MkKxV2FPT0WU
COR-L279 M3zzWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTJ4Lke5NlIh|ryP Mk\rV2FPT0WU
LU-165 MlHzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrFTWM2OD1{OD6wPFYyKM7:TR?= M{\6eXNCVkeHUh?=
COLO-800 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLmTWM2OD1{OD6yPVU3KM7:TR?= MX;TRW5ITVJ?
ETK-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLURY95UUN3ME2yPE4{PDR4IN88US=> NWHLdWxlW0GQR1XS
LNCaP-Clone-FGC NH;1XGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfJVmF{UUN3ME2yPU46OjhzIN88US=> NVHDTWhbW0GQR1XS
SIG-M5 NIfscFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlLyTWM2OD1|MD63PVUzKM7:TR?= NUn0eXVRW0GQR1XS
NB6 MmfYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7LTWM2OD1|MD65OVA{KM7:TR?= MnnVV2FPT0WU
NCI-H2107 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTNzLkKzN|gh|ryP MV;TRW5ITVJ?
SNU-C1 NYXjeYJPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnRUlZrUUN3ME2zNU4{OTJ4IN88US=> MY\TRW5ITVJ?
JAR M2qwNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVrEc3VTUUN3ME2zNU4{Pzl7IN88US=> NI\2VpJUSU6JRWK=
L-363 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfBRZk3UUN3ME2zNk4zOTR2IN88US=> MXzTRW5ITVJ?
EW-24 Ml[2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXuTWM2OD1|Mj6zOFc1KM7:TR?= NWTiUGc4W0GQR1XS
NB69 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFmwT4JKSzVyPUOzMlY1PTRizszN NX\s[3FKW0GQR1XS
EW-13 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUjOPXVZUUN3ME2zN{45QTZ7IN88US=> MoH0V2FPT0WU
Ramos-2G6-4C10 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\4TWM2OD1|ND6yPVk{KM7:TR?= MlHsV2FPT0WU
TE-11 NX7KVok5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHLPbIRKSzVyPUO0MlQ5OjJizszN NGTiTIxUSU6JRWK=
L-428 NEnzOlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTN2Lke1N|Yh|ryP NYjBV|FsW0GQR1XS
KP-N-YN NWrzTHFWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTN2LkmwOVch|ryP MV;TRW5ITVJ?
CGTH-W-1 NYDZTGRyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXHLcFJ3UUN3ME2zOk46ODR6IN88US=> NFe2NmZUSU6JRWK=
K-562 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTN5LkC4OlQh|ryP MYDTRW5ITVJ?
NCI-H1299 M4\4O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1HQUGlEPTB;M{iuNVYxOyEQvF2= NUHROXY1W0GQR1XS
RCC10RGB MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjmTWM2OD1|OD6yNFg{KM7:TR?= NULW[JdiW0GQR1XS
NCI-SNU-16 NH3ZV3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWHm[4JzUUN3ME2zPE42PjV|IN88US=> M3\We3NCVkeHUh?=
LC-2-ad NInZNGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYLJR|UxRTN7LkSzN|ch|ryP MU\TRW5ITVJ?
MHH-PREB-1 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1TEOmlEPTB;M{muO|M5QCEQvF2= MkDEV2FPT0WU
NCI-H64 NWr0OFlbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIPlVJdKSzVyPUSwMlA6PDhizszN MmrQV2FPT0WU
LB996-RCC MmLnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\YS2lEPTB;NECuPFcyPiEQvF2= NFe4bnBUSU6JRWK=
DEL NYXGXFhTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTRzLkS0NFUh|ryP NILxbVlUSU6JRWK=
MLMA MkG4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXpTWM2OD12MT63OVk2KM7:TR?= NV;qOlRtW0GQR1XS
SBC-1 NWrZVldXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2DJTGlEPTB;NEKuNVgxPiEQvF2= NY\MSGlQW0GQR1XS
MPP-89 NVPEW2pjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTR{LkW4O|Uh|ryP NXj2N4VJW0GQR1XS
MV-4-11 M{TvT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnvcXhKUUN3ME20Nk46ODZ5IN88US=> NHHBPFRUSU6JRWK=
EoL-1- NFn0d5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTR2LkG1Olgh|ryP MYrTRW5ITVJ?
CW-2 MkDNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TJeWlEPTB;NESuPFM1OiEQvF2= NFf2VlZUSU6JRWK=
HT MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILvPVNKSzVyPUS1MlcxODdizszN NF;uT5JUSU6JRWK=
SW954 M{Lue2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUTBbmZJUUN3ME20O{41OTJ6IN88US=> M3HpOHNCVkeHUh?=
A3-KAW NYq4Nm9KT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWi3Z405UUN3ME20PU45ODZzIN88US=> NWLIUGRYW0GQR1XS
TC-YIK NGXiRWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTVyLkCzOlMh|ryP MYrTRW5ITVJ?
SW962 NIDGcllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjnTWM2OD13ND64N|U4KM7:TR?= M2q5SXNCVkeHUh?=
KP-N-RT-BM-1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2HsZmlEPTB;NU[uOlY{QCEQvF2= NWnR[mVFW0GQR1XS
NCI-H1395 NXfXfng1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlT0TWM2OD13OD64NVczKM7:TR?= MXzTRW5ITVJ?
RPMI-8402 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfYWI5KSzVyPUW4Mlk2OjZizszN NU\mVZFxW0GQR1XS
SCH NU\z[XFqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2jvdmlEPTB;NkCuPVY{QCEQvF2= MkXQV2FPT0WU
NCI-H2196 NIHCNWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFLofYZKSzVyPU[xMlI{OSEQvF2= NHTYZYxUSU6JRWK=
LOXIMVI M4XVTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfBZoYxUUN3ME22NU45OjZ4IN88US=> NVvHeolSW0GQR1XS
TGBC24TKB NGHUSY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3r0Z2lEPTB;NkKuNVQ6OSEQvF2= MlXaV2FPT0WU
SK-MEL-2 M1TQOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV\JR|UxRTZ|Lkm4PVIh|ryP NX3VRVl5W0GQR1XS
U-698-M MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTZ6LkW2PFch|ryP MYTTRW5ITVJ?
NCI-H1522 NF;rbItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHhTWM2OD14OT6wNFQ4KM7:TR?= NXy0RYJVW0GQR1XS
UACC-812 NY\wbWlZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{DJcmlEPTB;NkmuOVIxQSEQvF2= NEDoWWNUSU6JRWK=
MHH-CALL-2 MmLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTdyLkC2JO69VQ>? MlnWV2FPT0WU
NB5 MkfKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVLDb2JPUUN3ME23NE4{PDZ6IN88US=> NILEbVBUSU6JRWK=
KARPAS-299 NHjTWoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEXWOppKSzVyPUewMlQ1PDdizszN MVLTRW5ITVJ?
NCI-H1694 M1nE[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfpT|RKSzVyPUexMlA{OiEQvF2= M2C1SnNCVkeHUh?=
NCI-H82 NFvuepRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4DrSGlEPTB;N{GuPVUxPyEQvF2= NVvq[206W0GQR1XS
SCC-15 NH;S[GhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWXJR|UxRTd{LkO0JO69VQ>? MkjlV2FPT0WU
NCI-H1436 NUfpWZhLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHhS5dXUUN3ME23Nk44PDV4IN88US=> MmXNV2FPT0WU
ATN-1 NFW1NXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkDNTWM2OD15ND61NFUh|ryP Ml;uV2FPT0WU
RPMI-8866 NXHVc|FOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlG3TWM2OD15ND63OVA6KM7:TR?= MlewV2FPT0WU
HCC1599 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2W0TGlEPTB;N{SuPFc{OiEQvF2= M33V[nNCVkeHUh?=
NCI-H1155 NV\ZRnJ7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITYZ|FKSzVyPUe0Mlk{PjdizszN M{Pp[nNCVkeHUh?=
DOHH-2 NX;6SotGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1rrTGlEPTB;N{SuPVUyPCEQvF2= NWDNVm56W0GQR1XS
SK-NEP-1 NVjVPHY{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV:3TVczUUN3ME23OU4xPzV2IN88US=> MVnTRW5ITVJ?
HCC1187 NVjTXYd4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYPNd4N{UUN3ME23O{43OTJ{IN88US=> NXW2c3J3W0GQR1XS
NCI-H322M M2D5eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoLXTWM2OD15OD6zO|A6KM7:TR?= NXuzfZl{W0GQR1XS
NCI-H526 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHfKTYRKSzVyPUe4MlU5PzdizszN MkC4V2FPT0WU
NCI-H2171 NIXN[JdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fSPGlEPTB;N{muOFE{PiEQvF2= NYmz[VQ6W0GQR1XS
COLO-668 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vyUGlEPTB;OEGuOVg5PCEQvF2= MU\TRW5ITVJ?
RS4-11 M{LnPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVnJR|UxRTh{LkK1NFUh|ryP MoKyV2FPT0WU
NCI-H716 NF;6ZplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoXCTWM2OD16Mj65NFc2KM7:TR?= MoTMV2FPT0WU
LU-134-A MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3;ETWlEPTB;OEOuNVM2OSEQvF2= NH6xWmJUSU6JRWK=
RPMI-8226 M3K5O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHyTWM2OD16ND6yNVA4KM7:TR?= NHTPbHJUSU6JRWK=
KY821 NGixbVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUC1[XNTUUN3ME25NU43PTVzIN88US=> MVrTRW5ITVJ?
ECC4 M4TLWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUewXZpQUUN3ME25N{45OjZ7IN88US=> NH;K[ZFUSU6JRWK=
EW-3 MoXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEDqVmdKSzVyPUm0MlkxQDFizszN NVnlfndJW0GQR1XS
NB7 NIj1cGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mkf1TWM2OD17NT63O|g3KM7:TR?= NXXDb2tSW0GQR1XS
NCI-H720 MmXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnK1TWM2OD17OD60NFYyKM7:TR?= NHzYe5FUSU6JRWK=
NCI-H446 M2rIWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4r4cWlEPTB;OUmuO|U5QCEQvF2= MnPRV2FPT0WU
NCI-H889 M{HGdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHiwWYZKSzVyPUGwOE4zPDJizszN M1fWN3NCVkeHUh?=
EW-22 M3fxV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3r1PGlEPTB;MUC2MlE6KM7:TR?= M{KxdnNCVkeHUh?=
BV-173 NX3TWWE1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYnJR|UxRTFyOD63Nlgh|ryP MXTTRW5ITVJ?
WSU-NHL M3iwbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{HoW2lEPTB;MUC5MlY4OSEQvF2= MmPIV2FPT0WU
MN-60 M1\DS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTFyOT62PUDPxE1? NXTuepR3W0GQR1XS
DG-75 MoraS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jaWmlEPTB;MUGzMlM2OiEQvF2= M2XnSXNCVkeHUh?=
DMS-79 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{C0VWlEPTB;MUG3MlM5OiEQvF2= MmnpV2FPT0WU
SK-MEL-1 NUT4OFVrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7SSHJKSzVyPUGxPE4xODlizszN MnLnV2FPT0WU
DMS-153 M3i5N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoLETWM2OD1zMkGuO|Q2KM7:TR?= MYPTRW5ITVJ?
NCI-H510A M1m5Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTF{Nz6zNkDPxE1? M3nTW3NCVkeHUh?=
BE-13 NHTlW3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NG\VXHlKSzVyPUGzOE4xPDRizszN MX7TRW5ITVJ?
KP-N-YS MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVzJR|UxRTF|OT63N|Yh|ryP NGXH[4dUSU6JRWK=
SUP-T1 MlLTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVnhPVB7UUN3ME2xOFMvPzB6IN88US=> MXvTRW5ITVJ?
EW-12 M3rlO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHSRYpKSzVyPUG0OE43QTlizszN MYjTRW5ITVJ?
NB14 M3LpXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml\wTWM2OD1zNEeuNFgzKM7:TR?= NYfMUpJ2W0GQR1XS
MDA-MB-134-VI M2n1PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXDcJZKSzVyPUG0PE4zPjhizszN Mnm2V2FPT0WU
NCI-H1770 NFvCOGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHu0e2tKSzVyPUG1Ok4zPzlizszN M336N3NCVkeHUh?=
TUR M4PqSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NG\kcXRKSzVyPUG2O{45PyEQvF2= NG\VenlUSU6JRWK=
NCI-H1417 M4q3cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPVdXFKSzVyPUG4NE4{OzFizszN NX\5OVNrW0GQR1XS
IMR-5 M1PXOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3ruOGlEPTB;MUixMlU4OSEQvF2= MXHTRW5ITVJ?
NCI-H226 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4LLRWlEPTB;MUi4Mlg3PiEQvF2= NXnSNpJOW0GQR1XS
NCI-H187 NVTnUWdMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTF7MD6wOlQh|ryP NH3LN|lUSU6JRWK=
SF539 MnXzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIP0ZYlKSzVyPUG5Nk44OjhizszN MX3TRW5ITVJ?
TALL-1 NUL2b|FoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fOWGlEPTB;MUm4MlMxPCEQvF2= MmK4V2FPT0WU
TE-441-T MoHiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXz0RndQUUN3ME2xPVkvPzN7IN88US=> NXn5SZJFW0GQR1XS
REH MmjIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4LKemlEPTB;MkO2MlYzPiEQvF2= NVvuTXhSW0GQR1XS
MS-1 NGDufYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEXGV3ZKSzVyPUKzPU4yOjFizszN M4PFVXNCVkeHUh?=
THP-1 MlX4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{nUXmlEPTB;Mk[0Mlc{QCEQvF2= NED0eHpUSU6JRWK=
NCI-H1838 MlfWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\YfWlEPTB;MkexMlQ2PiEQvF2= M{joNXNCVkeHUh?=
P30-OHK M4DtcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoLqTWM2OD1{OEOuPFQ4KM7:TR?= NHfXWZpUSU6JRWK=
C8166 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTN2NT6zN|gh|ryP MV7TRW5ITVJ?

多くの細胞株試験データを見る場合、クリックしてください

体内試験 Administration of MG-132 effectively rescues the expression levels and plasma membrane localization of dystrophin, β-dystroglycan, α-bdystroglycan, and α-sarcoglycan in skeletal muscle fibers from mdx mice, reduces muscle membrane damage, and ameliorates the histopathological signs of muscular dystrophy. [7] MG-132 treatment significantly reduces immobilization-induced skeletal muscle atrophy in mice, by downregulating the muscle-specific ubiquitin ligases atrogin-1/MAFbx and MuRF-1 mRNA. [8]

お薦めの試験操作(参考用のみ)

キナーゼ試験:

[1]

+ 展開

Measurement of inhibitory activities of MG-132 against 20S proteasome:

The reaction mixture for the 20S proteasome inhibitory assay contains 0.1 M Tris-acetate, pH 7.0, 20S proteasome, MG-132, and 25 μM substrate dissolved in dimethyl sulfoxide in a final volume of 1 mL. After incuba tion at 37 °C for 15 minutes, the reaction is stopped by the addition of 0.1 mL of 10% SDS and 0.9 mL of 0.1M Tris acetate, pH 9.0. The fluorescence of the reaction products is measured. To determine the IC50 against 20S proteasome, various concentrations of MG-132 are included in the assay mixture.
細胞試験:

[3]

+ 展開
  • 細胞株: KIM-2, HC11, and ES
  • 濃度: Dissolved in DMSO, final concentrations ~25 μM
  • 反応時間: 24 and 48 hours
  • 実験の流れ:

    Cells are exposed to various concentrations of MG-132 for 24, and 48 hours. Supernatant and monolayer cells are harvested by centrifugation and fixed in 70% ethanol in PBS for staining with acridine orange. Equal volumes of cells and acridine orange (5 mg/mL in PBS) are mixed on a microscope slide and examined by fluorescence microscopy. For annexin V analysis, cells are harvested by centrifugation and stained with annexin V and propidium iodide. For cell cycle analysis, cells are rehydrated in PBS at room temperature for 10 minutes, followed by staining with propidium iodide (5 mg/mL). All samples are analyzed using a Coulter Epics XL flow cytometer.


    (参考用のみ)
動物試験:

[7]

+ 展開
  • 動物モデル: Male mdx (C57BL/10ScSn DMD mdx) mice
  • 製剤: Dissolved in DMSO, and diluted in PBS
  • 投薬量: ~10 μg/kg/day
  • 投与方法: Injection
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 90 mg/mL (189.22 mM)
Ethanol 25 mg/mL (52.56 mM)
Water Insoluble
体内 左から(NMPから)右の順に溶剤を製品に加えます:
4% DMSO+30% PEG 300+20% propylene glycol+ddH2O
混合させたのち直ちに使用することを推奨します。
2mg/mL

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報

分子量 475.62
化学式

C26H41N3O5

CAS No. 133407-82-6
保管
in solvent
別名 N/A

便利ツール

モル濃度計算器

モル濃度計算器

解決のために必要とされるマス、ボリュームまたは濃度を計算してください。

マス (g) = 濃度 (mol/L) x ボリューム (L) x 分子量 (g/mol)

モル濃度計算器方程式

  • マス
    濃度
    ボリューム
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備することを要求される希釈剤を計算してください. セレック希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 輸入 輸出 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

マス 濃度 ボリューム 分子量

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

  • * 必須

よくある質問(FAQ)

  • 質問1:

    I want to know whether it contains EDTA or other chelating agent in this product(S2619)?

  • 回答:

    Our S2619 MG-132 doesn't contain EDTA or other chelating agent.

Proteasomeシグナル伝達経路

Proteasome Inhibitors with Unique Features

相関Proteasome製品

Tags: MG-132を買う | MG-132 ic50 | MG-132供給者 | MG-132を購入する | MG-132費用 | MG-132生産者 | オーダーMG-132 | MG-132化学構造 | MG-132分子量 | MG-132代理店
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