Y-27632 2HCl

製品コードS1049

Y-27632 2HCl化学構造

分子量(MW):320.26

Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.

サイズ 価格(税別)  
In DMSO JPY 27800
JPY 13600
JPY 21900
JPY 30200
JPY 96600
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文献中Selleckの製品使用例(153)

製品安全説明書

ROCK阻害剤の選択性比較

生物活性

製品説明 Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
ターゲット
ROCK1 (p160ROCK) [1]
(Cell-free assay)
ROCK2 [6]
(Cell-free assay)
140 nM(Ki) 300 nM(Ki)
体外試験

Y-27632 2HCl inhibits ROCK-II while displaying little activity against PKC, cAMP-dependent protein kinase and myosin light-chain kinase (MLCK) with Ki of 26 μM, 25 μM and > 250 μM, respectively, as well as PKA activated by another Rho-family GTPase member, Cdc42. Y-27632 2HCl inhibits smooth-muscle contraction induces by various agonists including phenylephrine, histamine, acetylcholine, serotonin, endothelin, and thromboxane with IC50 of 0.3-1 μM, by selectively inhibiting Ca2+ sensitization. Y-27632 2HCl suppresses Rho-induced, p160ROCK-mediated formation of stress fibres in cultured cells. [1] Y-27632 2HCl treatment blocks both Rho-mediated activation of actomyosin and LPA-stimulated invasive activity of MM1 cells in a concentration-dependent manner. [2] Y-27632 2HCl treatment is not only sufficient to initiate formation of exuberant axonal processes but also facilitates axonal maturation during the very early stages of axonogenesis, while largely sparing axon elongation. [3] In human embryonic stem (hES) cells, Y-27632 2HCl treatment at 10 μM markedly diminishes dissociation-induced apoptosis even in serum-free suspension (SFEB) culture, increases cloning efficiency (from ~1% to ~27%), facilitates subcloning after gene transfer, and enables SFEB-cultured hES cells to survive and differentiate into Bf1+ cortical and basal telencephalic progenitors. [4]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Swiss 3T3 cells M33MZ2Z2dmO2aX;uJGF{e2G7 M4X0W|ExKM7:TR?= M3\RVFIhcA>? M2SzXmROW09? NGO3[lRKdmirYnn0d{B1cGViYYPz[Y1jdHlib3[gcYlkem:2dXL1cIV{KGGwZDDpcpRmem2nZHnheIUh\mmuYX3lcpR{KHSxIH\vdo0h\Xi2ZX7k[YQheHKxY3Xzd4V{ NFzkNXY6PjR5NkW0
N1E-115 M{TIU2Z2dmO2aX;uJGF{e2G7 NFXJfngyOCEQvF2= NEjTWoYzKGh? MmfHSG1UVw>? MWPJcohq[mm2czD0bIUh[XO|ZX3icJkhd2ZibXnjdo91fWK3bHXzJIFv\CCrboTldo1m\GmjdHWg[olt[W2nboTzJJRwKG[xcn2g[Zh1\W6mZXSgdJJw[2W|c3Xz MYe5OlQ4PjV2
HeLa Ml3USpVv[3Srb36gRZN{[Xl? M3zKVVExKM7:TR?= NEjZTlI{OCCvaX6= M1zySWlvcGmkaYTzJJRp\SCob4LtZZRqd25ib3[gd5Rz\XO|IH\pZoVzeyCjbnSgeIhmKGG|c3XtZox6KG:oII\pcoN2dGmwLXPvcpRicW6rbneg[o9k[WxiYXTo[ZNqd26| M1zNfFk3PjhyN{K=
CCL39 MYjGeY5kfGmxbjDBd5NigQ>? M1HUTVMxKM7:TR?= M3\qflMxKG2rbh?= NV;pZ5ZsS2:vcHzleIVtgSCjYn;sbZNp\XNiYXP0bZZifGmxbjDv[kBP[S2KIHX4Z4hidmencjDOTGUyKGK7IHnueIVoemmwcx?= M{CyTlk3QTN|OEK=
Mesothelial cells from rat mesentery NXjiR|ZVUW64YYPpeoUhSXO|YYm= NUntbmFzOzBizszN MXWyNEBp NFroTlRDdG:la4OgbY53[XOrdnWgZYN1cX[rdIm= NHTMdXc6QTNyOEey
NIH3T3 M4C2UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmSzNVAh|ryP NGe4NY8yQCCm MXnEc4V{KG6xdDDpcohq[mm2IHPlcIwh\3Kxd4To NIDYdowyODB{MUO4Oi=>
Dbl-d MlL4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUniZ4ROOTBizszN M{D5R|E5KGR? NIjUcYdUfHKxbnfsfUBqdmirYnn0d{Bk\WyuIHfyc5d1cA>? M37DUFExODJzM{i2
Dbl-e MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV[xNEDPxE1? NV3jcHhXOThiZB?= MXzNc4RmemG2ZXz5JIlvcGmkaYTzJINmdGxiZ4Lve5Rp MVSxNFAzOTN6Nh?=
mNET1-d NYjYfJoyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkK4NVAh|ryP MUSxPEBl NXjpeJlIW3S{b37ncJkhcW6qaXLpeJMh[2WubDDndo94fGh? NHq5XWgyODB{MUO4Oi=>
mNET1-e Mkm5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHHo[noyOCEQvF2= MVixPEBl NX7nbWR3W3S{b37ncJkhcW6qaXLpeJMh[2WubDDndo94fGh? NVfHfoEyOTByMkGzPFY>
Ras-2 NGnmZYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmL3NVAh|ryP NXiyWGxrOThiZB?= MVfTeJJwdmeueTDpcohq[mm2czDj[YxtKGe{b4f0bC=> MlruNVAxOjF|OE[=
Ras-4 NYHDXXRuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTycXVZOTBizszN NHvWOWcyQCCm NXr4WI9EW3S{b37ncJkhcW6qaXLpeJMh[2WubDDndo94fGh? NW\ncIVkOTByMkGzPFY>
Src-1 MnfZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVj5c2Q1OTBizszN NIiwO3oyQCCm NG\pfppFd2W|IH7veEBqdmirYnn0JINmdGxiZ4Lve5Rp M1ntWFExODJzM{i2
Src-4 M2G1NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{[yVFExKM7:TR?= MlzNNVgh\A>? NIHFWYdFd2W|IH7veEBqdmirYnn0JINmdGxiZ4Lve5Rp M3OyXFExODJzM{i2
NIH3T3 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MknhNVAh|ryP MWOxPEBl NHf3UItFd2W|IH7veEBqdmirYnn0JINmdGxiZ4Lve5Rp MnnZNVAxOjF|OE[=
Src-1 M323[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYn0WIpLOTBizszN MX6xPEBl MlzZSI9meyCwb4SgbY5pcWKrdDDj[YxtKGe{b4f0bC=> M{jOflExODJzM{i2
Src-2 NFz5VIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXzb2s5OTBizszN MoPJNVgh\A>? NEH0cJVFd2W|IH7veEBqdmirYnn0JINmdGxiZ4Lve5Rp NXjzZotVOTByMkGzPFY>
SW620 NXTaWFJIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHfyWoQyOCEQvF2= MXKxPEBl NWPmfZlYTG:nczDuc5QhcW6qaXLpeEBk\WyuIHfyc5d1cA>? NFjZNpoyODB{MUO4Oi=>
HCT15 NUe2NVVXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPDUZZOOTBizszN NHrxRWUyQCCm NI\kUlRFd2W|IH7veEBqdmirYnn0JINmdGxiZ4Lve5Rp NXXsRWYzOTByMkGzPFY>
HCT116 NWXDV2VFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXH2W|hlOTBizszN MVOxPEBl MofyV5Rzd26pbImgbY5pcWKrdIOgZ4VtdCCpcn;3eIg> NWLoZoxPOTByMkGzPFY>
LS174T M{fhemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{K0UFExKM7:TR?= NFKzVm4yQCCm NFL1WXFOd2SncnH0[Yx6KGmwaHnibZR{KGOnbHyg[5Jwf3Sq NYjZcVl3OTByMkGzPFY>
Neonatal rat ventricular myocytes NULwbFRCTnWwY4Tpc44hSXO|YYm= MnPZNVAh|ryP M{nQS|Q5KGh? MVTJcohq[mm2czDFWE0yNWmwZIXj[YQhcW6lcnXhd4V{KGmwIIDyc5RmcW5ic4nueIhme2m|LDDj[YxtKHOrenWgZY5lKG27b3\pZpJqdGyjcjDvdodidmm8YYTpc44> NFj6O2oyODN6Nk[xNy=>
Stellate Cell NVn0O49lTnWwY4Tpc44hSXO|YYm= NGLNXGkzPSEQvF2= MX2xOUBucW5? MWnJcohq[mm2czDmc5Ju[XSrb36gc4YhTi2jY4TpckB{fHKnc4Og[olj\XK|IHHu[EBxcG:|cHjvdplt[XSrb36gc4YhdXmxc3nuJIxq\2i2IHPoZYlv M{G1VVExPjByNEm2
Rat Vascular Smooth Muscle Cells NEHDbmdHfW6ldHnvckBCe3OjeR?= MX:xNEDPxE1? NIHPd5EzKGh? MkHYTY5pcWKrdIOgZY5ocW:2ZX7zbY4hUUlvaX7keYNm\CCqeYDldpRzd3CqeR?= NWG4bGJCOTB4NEKzNVc>
PC3 M4rxSmZ2dmO2aX;uJGF{e2G7 M1XYWVI2KM7:TR?= NUCyTo5lOSCq MX3JcoR2[2W|IH3vdpBpd2yxZ3njZYwh[2ijbnfldy=> Mkm1NVA4OjB2N{G=
PC3 MXXNbYdz[XSrb36gRZN{[Xl? NUH4[lByOjVizszN M1rGOlEhcA>? NESzTZpKdmirYnn0d{B1cGViQl3GRk1EVSCjbnSgeIhmKEWJRj3zeIlufWyjdHXkJI1q\3KjdHnvci=> MknXNVA4OjB2N{G=
PC3 NFfqSnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVrTR40xOjVizszN NVPaZnF[OTdiaB?= NVPDN2o{TG:nczDuc5QhcW6qaXLpeEBk\WyuIHfyc5d1cA>? NI\RNJEyODd{MES3NS=>
LNCaP NGTOdVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NI\hfoQzPSEQvF2= MUCxO{Bp MWLEc4V{KG6xdDDpcohq[mm2IHPlcIwh\3Kxd4To NEfGOVkyODd{MES3NS=>
Rat hepatic stellate cells NGXmXmpHfW6ldHnvckBCe3OjeR?= MXezNEDPxE1? M4XablQ5KGh? MWPEbY1qdmm|aHXzJJRp\SCyaH;zdIhwenmuYYTpc44hd2ZiRYLrNkwh[W6mIHTlZ5Jm[XOnczDu[ZchTE6DIIP5cpRp\XOrcx?= NXvlRmhUOTB6NEW2OlM>
Pancreatic acinar cells NFjjZlBHfW6ldHnvckBCe3OjeR?= MWOxNOKh|ryP M3\w[FcxKG2rbh?= NImxbnJRd3SnboTpZZRmeyCFQ1utd5RqdXWuYYTl[EBx[W6lcnXheIlkKGWweont[UB{\WO{ZYTpc44> NFfFNY0yOjd2NUC4NC=>
C2C12 MU\GeY5kfGmxbjDBd5NigQ>? NE\w[GYyOMLizszN Mk\xOkBp M1rPPXBz\X[nboTzJJRp\SC|ZYLpcoUheGixc4Doc5J6dGG2aX;uJI9nKEmUUz2xJIlv\HWlZXSgZpkhcW6|dXzpckBidmRxb4KgWG5HNc7z M4\iU|E3OjZ5MUK0
PC 12 M3TM[mZ2dmO2aX;uJGF{e2G7 MXyxNOKh|ryP NWf1c4NGOjRiaB?= M3S4fWF1fGWwdXH0[ZMh[2G2ZXPoc4xidWmwZTDibY9{gW62aHXzbZM> NGHNWm4yPjJzOUSyOC=>
Cynomolgus monkey embryonic stem cells MUXDfZRwfG:6aXOgRZN{[Xl? NFTsOmozOCEEtV2= NHTVfW4zPCCq NUX6UpdlWHKxbX;0[ZMh[3mHUzDj[YxtKHO3co\peoFt NVfnPI9rOTh7NEC4OVU>
TSGH 8301 MWXNbYdz[XSrb36gRZN{[Xl? M3TYUFIxKML3TR?= M2\zPFEhcA>? NXHnR5dsUW6lcnXhd4V{KGOnbHygcYloemG2aX;u MlTuNVk5QTZ2N{W=
Swiss3T3 NUfOV4YzS2:ub375MYZwem2rbnegRZN{[Xl? NEKw[W4yOCEEtV2= MUexN{Bl MoXUTY5kemWjc3XzJJBzd3O2YYTlJINmdGxiY3;sc456NW[xcn3pcoch[WO2aY\peJk> NIOwZo4zOTR4NEmwNi=>
HT22 M{K3UmN6fG:2b4jpZ{BCe3OjeR?= M1\CRlExKML3TR?= NH2zNWoyOyCq MXLQdo91\WO2czDh[4FqdnO2IHfseZRidWG2ZT3pcoR2[2WmIH7leZJwdmGuIHTlZZRp NWjiU2NHOjJ6MUC4N|U>
Salivary gland stem cells M17zU2Z2dmO2aX;uJGF{e2G7 MlfQNVAhyrWP M1fRbFch\A>? NWPub45TWmWmdXPld{BUT1OFIIPlcoV{[2WwY3W= NVO4PGpYOjV6MES1OlA>

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アッセイ
Methods Test Index PMID
Western Blot
p-LIMK1(Thr508); 

PubMed: 24704720     


Immunoblot analysis of HCT116 and HCT116 SMAD4-/- cells. Cells were transfected transiently with either BMPR2 or pcDNA vector. Subsequently, cells were treated with 2.5 μmol/L of ROCK inhibitor (Y-27632) or PBS. Blots were incubated with antibodies against pLIMK1/2 and p-cofilin. Actin was used as a loading control.

p-LIMK2(Thr505); 

PubMed: 24704720     


Immunoblot analysis of HCT116 and HCT116 SMAD4-/- cells. Cells were transfected transiently with either BMPR2 or pcDNA vector. Subsequently, cells were treated with 2.5 μmol/L of ROCK inhibitor (Y-27632) or PBS. Blots were incubated with antibodies against pLIMK1/2 and p-cofilin. Actin was used as a loading control.

p-Cofilin(Ser3); 

PubMed: 24704720     


Immunoblot analysis of HCT116 and HCT116 SMAD4-/- cells. Cells were transfected transiently with either BMPR2 or pcDNA vector. Subsequently, cells were treated with 2.5 μmol/L of ROCK inhibitor (Y-27632) or PBS. Blots were incubated with antibodies against pLIMK1/2 and p-cofilin. Actin was used as a loading control.

CDK2; 

PubMed: 26555939     


Western blot detected proteins changes pTR cells cultured with Y-27632. CDX2 was remarkably increased in Y-27632 treated pIVFTR-7 and pPATR-5 cells. pTR cells cultured without Y-27632 in the same condition are used as control. β-ACTIN serves as an endogenous control. 

KRT7; 

PubMed: 26555939     


Western blot detected proteins changes pTR cells cultured with Y-27632. CDX2 was remarkably increased in Y-27632 treated pIVFTR-7 and pPATR-5 cells. pTR cells cultured without Y-27632 in the same condition are used as control. β-ACTIN serves as an endogenous control. 

ROCK2; 

PubMed: 26555939     


Western blot detected proteins changes pTR cells cultured with Y-27632. CDX2 was remarkably increased in Y-27632 treated pIVFTR-7 and pPATR-5 cells. pTR cells cultured without Y-27632 in the same condition are used as control. β-ACTIN serves as an endogenous control. 

E-cadherin; 

PubMed: 27399334     


The expression and/or phosphorylation of E-cadherin and ROCKs downstream targets in SW-480-FOXM1D cells treated with Y-27632.

p-MLC2(Ser19); 

PubMed: 27399334     


The expression and/or phosphorylation of E-cadherin and ROCKs downstream targets in SW-480-FOXM1D cells treated with Y-27632.

24704720 26555939 27399334
Transwell migration assay
cell migration inhibition ; 

PubMed: 27694793     


Data represent mean ± SEM, n=3. Compared with control, * P<0.05, ** P<0.01. Compared with control, Y-27632, or EGCG, *** P<0.01.

27694793
Immunofluorescence
Neurotoxicity Assay; 

PubMed: 21362567     


Representations of neurodegeneration in H9-, HUF5- and G2019S-iPSC derived neurons when treated with neurotoxins, H2O2 and MG-132, and ROCK inhibitor Y-27632. Scale bar = 50 µm.

E-cadherin; 

PubMed: 24523903     


The localized patterns of E-cadherin and b-catenin were examined using specific antibodies through confocal laser microscopy. MCF-7 cells were cultured for 24 hrs in the absence or presence of Y-27632 (20 µM) to inhibit ROCK activity. 

beta-catenin; 

PubMed: 24523903     


The localized patterns of E-cadherin and b-catenin were examined using specific antibodies through confocal laser microscopy. MCF-7 cells were cultured for 24 hrs in the absence or presence of Y-27632 (20 µM) to inhibit ROCK activity. 

Phalloidin; 

PubMed: 27399334     


Triple IF staining for F-actin (phalloidin, green) E-cadherin (b) (red) and nuclei (DAPI, blue) showed decreased F-actin, increased E-cadherin and altered cell shape and size in SW-480-FOXM1D cells treated with the ROCKs inhibitor Y-27632 or fasudil (both 10 μM, for 24 h). Scale bar, 25 μm. 

21362567 24523903 27399334
Growth inhibition assay
cell proliferation ; 

PubMed: 24523903     


MCF-7 cells and MDA-MB-231 cells were cultured on tissue culture plates for four days with or without Y-27632 (20 µM). Relative cell proliferation rates were determined by the cell number assayed using CCK-8 kit. The data are expressed as the mean ± SD. n = 3 culture dishes. The p-value was less than 0.05 for comparisons between control (Control) and treatment groups (Y-27632) in MCF-7 cells. *, p<0.05.

24523903
ELISA
caspase-9; 

PubMed: 30320378     


Caspase-9 activity was measured via ELISA. Mst1-mediated casapse-9 activation was inhibited by Y-27632 in A549 cells. *P<0.05. Ad, adenovirus; Mst1, mammalian STE20-like kinase 1.

30320378
体内試験 Oral administration of Y-27632 2HCl at 30 mg/kg significantly decreases the blood pressure in a dose-dependent manner in spontaneous hypertensive rats, renal hypertensive rats, as well as deoxycorticosterone acetate (DOCA)-salt hypertensive rats. [1] When Y-27632 2HCl is continuously administered at a rate of 0.55 μL per hour by implanted pumps for 11 days tumor cell invasion (MM1 cells expressing Val14-RhoA in rats) is significantly delayed. [2] By inhibiting ROCK, Y-27632 2HCl treatment attenuates hypoxia-induced angiogenesis and vascular remodeling in the pulmonary circulation. [5] Pretreatment with Y-27632 has a protective effect against tumor formation in albino mice with Ehrlich ascites carcinoma. [7]

お薦めの試験操作(参考用のみ)

動物試験:[1] [7]
+ 展開
  • 動物モデル: Male Wistar rats with spontaneous or induced hypertension; Swiss albino mice with Ehrlich ascites carcinoma
  • 製剤: Dissolved in DMSO, and diluted in saline (Rat); 0.9% NaCl (Mice)
  • 投薬量: 30 mg/kg/day (Rat); 0-10 mg/kg (mice)
  • 投与方法: Orally (Rat); i.p. (Mice)
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 64 mg/mL (199.83 mM) warming
Water 14 mg/mL (43.71 mM)
Ethanol Insoluble
体内 左から(NMPから)右の順に溶剤を製品に加えます(文献ではなく、Selleckの実験によるデータ):
saline
混合させたのち直ちに使用することを推奨します。
10mg/mL

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報

分子量 320.26
化学式

C14H21N3O.2HCl

CAS No. 129830-38-2
保管
in solvent
別名 N/A

便利ツール

モル濃度計算器

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (g) = 濃度 (mol/L) x 体積 (L) x 分子量 (g/mol)

モル濃度計算器方程式

  • 質量
    濃度
    体積
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 入力 出力 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量 濃度 体積 分子量

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

  • * 必須

よくある質問(FAQ)

  • 質問1:

    Is there any data about the Amax (maximum attraction luminosity) and extinction coefficient of this compound?

  • 回答:

    The wavelength we used to test HPLC is 260nm while the extinction coefficient is unknown.

  • 質問2:

    Could this product be used in cell culture? Do you have any reference for this application?

  • 回答:

    Yes. The Y-27632 can be used in cell culture certainly. Here is the reference website: http://molpharm.aspetjournals.org/content/57/5/976.full.

ROCKシグナル伝達経路

ROCK Inhibitors with Unique Features

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Tags: Y-27632 2HClを買う | Y-27632 2HCl ic50 | Y-27632 2HCl供給者 | Y-27632 2HClを購入する | Y-27632 2HCl費用 | Y-27632 2HCl生産者 | オーダーY-27632 2HCl | Y-27632 2HCl化学構造 | Y-27632 2HCl分子量 | Y-27632 2HCl代理店
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細胞株 試験類型 濃度 培養時間 溶剤類型 活性叙述 PMID