FDA-approved Drug Library

目录号 L1300

A unique collection of 2607 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS).

サイズ 価格(税別)  
予めDMSOまたは水に溶解しています
2219300
4035400
最寄りの販売代理店を探す

お探しのディーラーが見当たらない場合は直接こちらのメールアドレスまでお問い合わせください：[email protected]

セレックの化合物ライブラリーはCOVID19研究に貢献しています

(日本)国立感染症研究所はセレックのFDA承認化合物を用いてスクリニーング実験を行い、研究から僅か3ヶ月以内にCOVID19
の治療薬候補を見出しました。本研究成果はBioRxivにて発表されました。doi: 10.1101/2020.04.14.039925。

お気に入りの分子或いは調達サービスにより、分子ライブラリーをカスタマイズします。
お客様自身のニーズを満たすために、弊社の製品を数量、状態（乾燥状態/固体或いはDMSO）等で選択できます。

FDA-approved Drug Library内容

Download theFDA-approved Drug Library - SDF
Download theFDA-approved Drug Library - XLSX
Download the Compound Library Usage Instructions- PDF

Selleckの分子ライブラリーが使用されている文献(253)

Selleck化合物ライブラリー使用例

  • 肝癌研究におけるGPCR Compound Libraryの使用例

    Nature.2019;574(7777):268-272

  • 大腸癌研究におけるKinase Inhibitor Library の使用例

    Nat Commun. 2019 16;10(1):2197

  • 抗ウイルス研究におけるFDA-approved Drug Libraryの使用例

    Cell Res. 2019;29(9):739-753

  • 代謝研究におけるFDA-approved Drug Library使用例

    Mov Disord. 2019;34(3):323-334

  • 白血病研究におけるEpigenetics Compound Libraryの使用例

    Blood. 2019 17;134(16):1323-1336

  • 癌免疫研究におけるInhibitor Libraryの使用例

    Cancer Immunol Res.2017;5(9):790-803

製品特性＆メリット

・FDAが認証した2607 種類の薬剤ライブラリーです。

HTS（High Throughput Screening） およびHCS（High Content Screening）に使用できます。

・全製品FDA,EMA,HMA,CFDA,PMDAなどの機関から承認済み、またはUSP,BP,EP,JP,Ph.Intなどの薬局方に情報が収載されています。

・FDAの新薬申請（NDA）または簡略化新薬申請（ANDA）情報を提供します。

・既存の薬剤を使用し新たなターゲットを見つけます。

・臨床試験を通じて、生物活性と安全性が確認されました。

・腫瘍、心臓病、抗炎症、免疫、神経精神病、鎮痛などに関連しています。

・構造、IC50、お客様からのレビューなど豊富な情報があります。

・NMRとHPLC検査で製品の高純度を保証しています。

・こちらがこのライブラリにおける化合物の認定機関です:

Approved institution Full name Country
                FDA U.S. Food and Drug Administration United States of America
                CFDA China Food and Drug Administration China
                EMA European Medicines Agency European
                HMA Heads Of Medicines Agency European
                NDC National Drug Code United States of America
                PMDA Pharmaceuticals and Medical Devices Agency Japan
                DMF Drug Master File United States of America

 

製品詳細情報

調合： 2300 compounds pre-dissolved in 10mM DMSO, 220 compounds pre-dissolved in 10mM water, 70 compounds pre-dissolved in 2mM DMSO and 17 compounds pre-dissolved in 2mM water
ケース： 96/384 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
安定性： in DMSO
in DMSO
出荷方式： ブルーアイス物流
包装： 不活性ガス（Inert gas）

FDA-approved Drug Library组成

HTS パートナ

他のライブラリー

  • FDA-approved & Passed Phase I Drug Library

    A unique collection of 2885 drugs that are marketed around the world or that have passed phase 1 clinical trials for high throughput screening (HTS) and high content screening (HCS).

  • Preclinical/Clinical Compound Library

    A unique collection of 2709 preclinical and clinical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-I

    A unique collection of 6748 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-Ⅱ

    A unique collection of 5076 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Kinase Inhibitor Library

    A unique collection of 1377 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Express-Pick Library

    A unique collection of 3924 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).

  • Natural Product Library

    A unique collection of 2198 natural products for high throughput screening (HTS) and high content screening (HCS).

  • Human Endogenous Metabolite Library

    532 small collections of human cell metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.

  • Alkaloid Compound Library

    A unique collection of 269 alkaloid compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Angiogenesis Related compound Library

    A unique collection of 224 small molecules used for angiogenesis research targeting Bcr-Abl,BTK,HIF,VEGFR,FGFR,FAK, etc.

  • Anti-Aging Compound Library

    A unique collection of 1439 anti-aging compounds used for aging related research.

  • Anti-alzheimer Disease Compound Library

    A unique collection of 475 small molecules for exploring the mechanism of Alzheimer's disease.

  • Antibiotics Library

    A unique collection of 302 antibiotics used for anti-infetion research in order to identify drug target and open up new mechanism and ways to treat human disease.

  • Anti-cancer Compound Library

    A unique collection of 3411 anti-cancer small molecules for 12 types of cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc.

  • Anti-cancer Compound Library (Verified by Broad Institute)

    A unique collection of 882 compounds with anticancer activity which has been verified by broad institute,half of the compounds are non-oncology drugs.

  • Anti-cancer Metabolism Compound Library

    A unique collection of 186 small molecules for cancer metabolism research.

  • Anti-Cardiovascular Disease Compound Library

    A unique collection of 685 anti-cardiovascular disease related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Anti-diabetic Compound Library

    A unique collection of 140 small molecules affecting the development of diabetes.

  • Anti-infection Compound Library

    A unique collection of 903 anti-infective small molecules with biological activity of antibiotics,antifungal drugs,anti-HIV,etc.

  • Antioxidant Compound Library

    A unique collection of 423 compounds used for exploring the relationship between anti-oxidation and some diseases such as aging,cancer,alzheimer's disease,parkinson's disease,diabetes,etc.

  • Antiviral Compound Library

    A unique collection of 336 antiviral compounds used for exploring novel antiviral drug.

  • Apoptosis Compound Library

    A unique collection of 664 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.

  • Autophagy Compound Library

    A unique collection of 780 small molecules with autophagy-inducing or autophagy-inhibiting activity.

  • Cambridge Cancer Compound Library

    A unique collection of 230 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).

  • Cell Cycle compound library

    A unique collection of 115 small molecule compounds used for cell cycle and related diseases research

  • CNS-Penetrant Compound Library

    A unique collection of 302 CNS-Penetrant compounds with biological activity for neurologic research.

  • Covalent Inhibitor Library

    A unique collection of 74 covalent Inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Cytoskeletal Signaling Pathway Compound Library

    A unique collection of 180 compounds used for research in cytoskeleton and cytoskeletal interactions.

  • DNA Damage/DNA Repair compound Library

    A unique collection of 493 small molecules used for DNA Damage and Repair research targeting PARP,ATM/ATR,Topoisomerase,DNA/RNA Synthesis etc.

  • Drug-like Compound Library

    A unique collection of 2006 drug-like compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Epigenetics Compound Library

    Selleck Epigenetic inhibitor Library contains various small molecule modulators (inhibitors and activators) with biological activity used for epigenetic research and associated assays.

  • FDA-approved Anticancer Drug Library

    A unique collection of 1520 approved drugs with anticancer activity used for high throughput screening(HTS) and high content screening(HCS).

  • Ferroptosis Compound Library

    A unique collection of 536 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.

  • Flavonoid Compound Library

    A unique collection of 185 flavonoid compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Fragment Library

    A unique collection of 939 Fragment compounds for Fragment-Based Drug Discovery (FBDD).

  • Glutamine Metabolism Compound Library

    A unique collection of 229 glutamine metabolism related compounds used for high throughput screening (HTS) and high content screening (HCS).

  • GPCR Compound Library

    Selleck GPCR Small Molecule Compound Library contains various small molecules targeting G protein coupled receptors with biological activity.

  • HIF-1 Signaling Pathway Compound Library

    A unique collection of 427 HIF-1 signaling pathway compounds used for oxygen sensing related research.

  • Highly Selective Inhibitor Library

    A unique collection of 312 validated bioactive compounds covering over 119 targets.

  • Histone modification compound library

    A unique collection of 191 compounds with biological activity used for histone modification research and associated assays

  • HTS Library for Drug Discovery

    A unique collection of 99040 compounds features numerous structurally diverse compounds and several alternate compositions.

  • Immunology/Inflammation Compound Library

    A unique collection of 1783 small molecules modulators (inhibitors and activators) with biological activity used for Immunology/Inflammation research and associated assays.

  • Inhibitor Library

    A unique collection of 3302 inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Ion Channel Ligand Library

    A unique collection of 227 small molecule modulators used for Ion channel research.

  • JAK/STAT compound library

    A unique collection of 39 small molecules used for research in JAK-STAT signaling pathway.

  • Macrocyclic Compound Library

    A unique collection of 104 macrocyclic compounds used for high throughput screening(HTS) and high content screening(HCS).

  • MAPK Inhibitor Library

    A unique collection of 166 small molecule inhibitors used for MAPK signaling research.

  • Medicine Food Homology Compound Library

    A unique collection of 374 medicine food homology compounds used for high throughput screening (HTS) and high content screening (HCS).

  • Metabolism Compound Library

    A unique collection of 1960 small molecules with biological activity in numerous metabolic pathway: glycometabolism, lipid metabolism, proteolysis, etc.

  • Methylation Compound Library

    A unique collection of 106 compounds used for researching the function of methylation in epigenetics,cancer,embryogenesis,etc.

  • Natural Organic Compound Library

    A unique collection of 1118 plant-derived natural organic compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Neuronal Signaling Compound Library

    A unique collection of 1076 small molecule compounds with biological activity used for neurologic research and associated assays

  • NF-κB Signaling Compound Library

    A unique collection of 303 small molecules used for NF-κB Signaling pathway research which plays a key role in immunology/inflammation and cancer.

  • Nucleoside Analogue Library

    A unique collection of 129 nucleoside analogues used for high throughput screening(HTS) and high content screening(HCS).

  • Obesity Compound Library

    A unique collection of 885 compounds used for research in obesity.

  • PI3K/Akt Inhibitor Library

    A unique collection of 254 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.

  • Protease Inhibitor Library

    A unique collection of 214 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).

  • Protein-protein Interaction Inhibitor Library

    A unique collection of 177 protein-protein Interaction(PPI) Inhibitors used for high throughput screening(HTS) and high content screening(HCS).

  • Pyroptosis Compound Library

    A unique collection of 428 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Small Molecule Immuno-Oncology Compound Library

    A unique collection of 115 Immuno-Oncology small molecules used for oncotherapy in conjunction with other drugs.

  • Stem Cell Signaling Compound Library

    A unique collection of 425 compounds with biological activity used for stem cell regulatory and signaling pathway research.

  • TGF-beta/Smad compound library

    A unique collection of 101 small molecules with biological activity used for TGF-beta/Smad pathway research.

  • Tyrosine Kinase Inhibitor Library

    Tyrosine Kinase Inhibitor library is ideal database for high-throughput screening (HTS) and cell based high-content screening (HCS).

  • Ubiquitination Compound Library

    A unique collection of 145 small molecules for Ubiquitination related research.