GPCR Compound Library

目录号 L2200

Selleck GPCR Small Molecule Compound Library contains various small molecules targeting G protein coupled receptors with biological activity.

サイズ 価格(税別)  
予めDMSOまたは水に溶解しています
1714700
2515500
最寄りの販売代理店を探す

お探しのディーラーが見当たらない場合は直接こちらのメールアドレスまでお問い合わせください：[email protected]

セレックの化合物ライブラリーはCOVID19研究に貢献しています

(日本)国立感染症研究所はセレックのFDA承認化合物を用いてスクリニーング実験を行い、研究から僅か3ヶ月以内にCOVID19
の治療薬候補を見出しました。本研究成果はBioRxivにて発表されました。doi: 10.1101/2020.04.14.039925。

お気に入りの分子或いは調達サービスにより、分子ライブラリーをカスタマイズします。
お客様自身のニーズを満たすために、弊社の製品を数量、状態（乾燥状態/固体或いはDMSO）等で選択できます。

GPCR Compound Library内容

Download theGPCR Compound Library - SDF
Download theGPCR Compound Library - XLSX

Selleckの分子ライブラリーが使用されている文献(46)

Selleck化合物ライブラリー使用例

  • 肝癌研究におけるGPCR Compound Libraryの使用例

    Nature.2019;574(7777):268-272

  • 大腸癌研究におけるKinase Inhibitor Library の使用例

    Nat Commun. 2019 16;10(1):2197

  • 抗ウイルス研究におけるFDA-approved Drug Libraryの使用例

    Cell Res. 2019;29(9):739-753

  • 代謝研究におけるFDA-approved Drug Library使用例

    Mov Disord. 2019;34(3):323-334

  • 白血病研究におけるEpigenetics Compound Libraryの使用例

    Blood. 2019 17;134(16):1323-1336

  • 癌免疫研究におけるInhibitor Libraryの使用例

    Cancer Immunol Res.2017;5(9):790-803

製品特性＆メリット

・Gタンパク質共役受容体をターゲットとした1006種類の化合物ライブラリーです。HTS（High Throughput Screening） およびHCS（High Content Screening）に使用できます。

・ライブラリーの化合物は全て生物活性と薬理活性を有しています。

・オーファンGPCR（Orphan GPCR）は機能未知なため、弊社のGPCR化合物ライブラリーを使用することで機能未知のGPCRsを選別し、新たなGPCR標的薬を見出す可能性があります。

・GPCR化合物ライブラリーは様々な受容体（5-HT受容体、ドーパミン受容体、オピオイド受容体、アドレナリン受容体、カンナビノイド受容体、代謝型グルタミン酸受容体、エンドセリン受容体など）を標的としています。

・構造的に多様で、薬効および細胞透過性が確認されています。

・詳しい構造説明と、お客様からのレビューなど豊富な情報があります。

・NMRとHPLC検査で製品の高純度を保証しています。

製品詳細情報

調合： 915 compounds pre-dissolved in 10mM DMSO, 60 compounds pre-dissolved in 10mM water, 27 compounds pre-dissolved in 2mM DMSO and 4 compounds pre-dissolved in 2mM water
ケース： 96/384 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
安定性： in DMSO
in DMSO
出荷方式： ブルーアイス物流
包装： 不活性ガス（Inert gas）

GPCR Compound Library组成

HTS パートナ

他のライブラリー

  • FDA-approved Drug Library

    A unique collection of 2611 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS).

  • FDA-approved & Passed Phase I Drug Library

    A unique collection of 2889 drugs that are marketed around the world or that have passed phase 1 clinical trials for high throughput screening (HTS) and high content screening (HCS).

  • Preclinical/Clinical Compound Library

    A unique collection of 2709 preclinical and clinical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-I

    A unique collection of 6753 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Bioactive Compound Library-Ⅱ

    A unique collection of 5076 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS).

  • Kinase Inhibitor Library

    A unique collection of 1447 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Express-Pick Library

    A unique collection of 3924 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).

  • Natural Product Library

    A unique collection of 2200 natural products for high throughput screening (HTS) and high content screening (HCS).

  • Human Endogenous Metabolite Library

    532 small collections of human cell metabolites, involving multiple metabolic pathways, which can be used for high-throughput screening, opening up new ways for humans to treat various diseases such as tumors.

  • Alkaloid Compound Library

    A unique collection of 269 alkaloid compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Angiogenesis Related compound Library

    A unique collection of 224 small molecules used for angiogenesis research targeting Bcr-Abl,BTK,HIF,VEGFR,FGFR,FAK, etc.

  • Anti-Aging Compound Library

    A unique collection of 1439 anti-aging compounds used for aging related research.

  • Anti-alzheimer Disease Compound Library

    A unique collection of 475 small molecules for exploring the mechanism of Alzheimer's disease.

  • Antibiotics Library

    A unique collection of 302 antibiotics used for anti-infetion research in order to identify drug target and open up new mechanism and ways to treat human disease.

  • Anti-cancer Compound Library

    A unique collection of 3411 anti-cancer small molecules for 12 types of cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc.

  • Anti-cancer Compound Library (Verified by Broad Institute)

    A unique collection of 882 compounds with anticancer activity which has been verified by broad institute,half of the compounds are non-oncology drugs.

  • Anti-cancer Metabolism Compound Library

    A unique collection of 186 small molecules for cancer metabolism research.

  • Anti-Cardiovascular Disease Compound Library

    A unique collection of 685 anti-cardiovascular disease related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Anti-diabetic Compound Library

    A unique collection of 140 small molecules affecting the development of diabetes.

  • Anti-infection Compound Library

    A unique collection of 903 anti-infective small molecules with biological activity of antibiotics,antifungal drugs,anti-HIV,etc.

  • Antioxidant Compound Library

    A unique collection of 423 compounds used for exploring the relationship between anti-oxidation and some diseases such as aging,cancer,alzheimer's disease,parkinson's disease,diabetes,etc.

  • Antiviral Compound Library

    A unique collection of 336 antiviral compounds used for exploring novel antiviral drug.

  • Apoptosis Compound Library

    A unique collection of 664 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.

  • Autophagy Compound Library

    A unique collection of 780 small molecules with autophagy-inducing or autophagy-inhibiting activity.

  • Cambridge Cancer Compound Library

    A unique collection of 230 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).

  • Cell Cycle compound library

    A unique collection of 115 small molecule compounds used for cell cycle and related diseases research

  • CNS-Penetrant Compound Library

    A unique collection of 302 CNS-Penetrant compounds with biological activity for neurologic research.

  • Covalent Inhibitor Library

    A unique collection of 74 covalent Inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Cytoskeletal Signaling Pathway Compound Library

    A unique collection of 180 compounds used for research in cytoskeleton and cytoskeletal interactions.

  • DNA Damage/DNA Repair compound Library

    A unique collection of 511 small molecules used for DNA Damage and Repair research targeting PARP,ATM/ATR,Topoisomerase,DNA/RNA Synthesis etc.

  • Drug-like Compound Library

    A unique collection of 2088 drug-like compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Epigenetics Compound Library

    Selleck Epigenetic inhibitor Library contains various small molecule modulators (inhibitors and activators) with biological activity used for epigenetic research and associated assays.

  • Ferroptosis Compound Library

    A unique collection of 536 compounds used for exploring the mechanism of ferroptosis which is an iron-dependent form of non-apoptotic cell death.

  • Flavonoid Compound Library

    A unique collection of 186 flavonoid compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Fragment Library

    A unique collection of 939 Fragment compounds for Fragment-Based Drug Discovery (FBDD).

  • Glutamine Metabolism Compound Library

    A unique collection of 229 glutamine metabolism related compounds used for high throughput screening (HTS) and high content screening (HCS).

  • HIF-1 Signaling Pathway Compound Library

    A unique collection of 427 HIF-1 signaling pathway compounds used for oxygen sensing related research.

  • Highly Selective Inhibitor Library

    A unique collection of 312 validated bioactive compounds covering over 119 targets.

  • Histone modification compound library

    A unique collection of 191 compounds with biological activity used for histone modification research and associated assays

  • HTS Library for Drug Discovery

    A unique collection of 99040 compounds features numerous structurally diverse compounds and several alternate compositions.

  • Immunology/Inflammation Compound Library

    A unique collection of 1783 small molecules modulators (inhibitors and activators) with biological activity used for Immunology/Inflammation research and associated assays.

  • Inhibitor Library

    A unique collection of 3302 inhibitors for high throughput screening (HTS) and high content screening (HCS).

  • Ion Channel Ligand Library

    A unique collection of 227 small molecule modulators used for Ion channel research.

  • JAK/STAT compound library

    A unique collection of 39 small molecules used for research in JAK-STAT signaling pathway.

  • Macrocyclic Compound Library

    A unique collection of 104 macrocyclic compounds used for high throughput screening(HTS) and high content screening(HCS).

  • MAPK Inhibitor Library

    A unique collection of 166 small molecule inhibitors used for MAPK signaling research.

  • Medicine Food Homology Compound Library

    A unique collection of 374 medicine food homology compounds used for high throughput screening (HTS) and high content screening (HCS).

  • Metabolism Compound Library

    A unique collection of 1960 small molecules with biological activity in numerous metabolic pathway: glycometabolism, lipid metabolism, proteolysis, etc.

  • Methylation Compound Library

    A unique collection of 106 compounds used for researching the function of methylation in epigenetics,cancer,embryogenesis,etc.

  • Natural Organic Compound Library

    A unique collection of 1130 plant-derived natural organic compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Neuronal Signaling Compound Library

    A unique collection of 1076 small molecule compounds with biological activity used for neurologic research and associated assays

  • NF-κB Signaling Compound Library

    A unique collection of 303 small molecules used for NF-κB Signaling pathway research which plays a key role in immunology/inflammation and cancer.

  • Nucleoside Analogue Library

    A unique collection of 129 nucleoside analogues used for high throughput screening(HTS) and high content screening(HCS).

  • Obesity Compound Library

    A unique collection of 885 compounds used for research in obesity.

  • PI3K/Akt Inhibitor Library

    A unique collection of 254 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.

  • Protease Inhibitor Library

    A unique collection of 214 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).

  • Pyroptosis Compound Library

    A unique collection of 428 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS).

  • Small Molecule Immuno-Oncology Compound Library

    A unique collection of 115 Immuno-Oncology small molecules used for oncotherapy in conjunction with other drugs.

  • Stem Cell Signaling Compound Library

    A unique collection of 425 compounds with biological activity used for stem cell regulatory and signaling pathway research.

  • TGF-beta/Smad compound library

    A unique collection of 101 small molecules with biological activity used for TGF-beta/Smad pathway research.

  • Tyrosine Kinase Inhibitor Library

    Tyrosine Kinase Inhibitor library is ideal database for high-throughput screening (HTS) and cell based high-content screening (HCS).

  • Ubiquitination Compound Library

    A unique collection of 145 small molecules for Ubiquitination related research.