Apoptosis Compound Library

目录号 L3300

A unique collection of 943 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.

サイズ

価格(税別)

予めDMSOまたは水に溶解しています
100uL/well (2mM or 10mM solution)	3752900
2x100uL/well (2mM or 10mM solution)	5353600

最寄りの販売代理店を探す

東京
北海道
東北
北関東
南関東
東海
北信越
近畿
中国
四国
九州

お探しのディーラーが見当たらない場合は直接こちらのメールアドレスまでお問い合わせください：[email protected]

具体的な在庫状況を確認してください。代表番号: 03-5615-9297 | 電子メール：[email protected]

セレックの化合物ライブラリーはCOVID19研究に貢献しています

(日本)国立感染症研究所はセレックのFDA承認化合物を用いてスクリニーング実験を行い、研究から僅か3ヶ月以内にCOVID19
の治療薬候補を見出しました。本研究成果はBioRxivにて発表されました。doi: 10.1101/2020.04.14.039925。

本研究成果はテレビニュース等での報道も行われました

お気に入りの分子或いは調達サービスにより、分子ライブラリーをカスタマイズします。
お客様自身のニーズを満たすために、弊社の製品を数量、状態（乾燥状態/固体或いはDMSO）等で選択できます。

Apoptosis Compound Library内容

Download theApoptosis Compound Library - SDF

Download theApoptosis Compound Library - XLSX

Download the Compound Library Usage Instructions- PDF

Selleckの分子ライブラリーが使用されている文献(76)

Cell Metab,2019,7;29(5):1166-1181.e6.

PubMed: 30799286 ( click the link to review the publication )

Nat Med,2017,23(4):405-408

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Nat Med,2014,20(8):954-60

PubMed: 24997607 ( click the link to review the publication )

Nat Commun,2020,14;11(1):1792.

PubMed: 32286289 ( click the link to review the publication )

Cancer Res,2020,15;80(4):832-842.

PubMed: 31888889 ( click the link to review the publication )

Stem Cell Reports,2020,14(3):478-492

PubMed: 32084387 ( click the link to review the publication )

Cancer Lett,2020,470:161-169

PubMed: 31765734 ( click the link to review the publication )

Cancer Lett,2020,469:195-206

PubMed: 31672491 ( click the link to review the publication )

Cell Death Dis,2020,2;11(3):158.

PubMed: 32123161 ( click the link to review the publication )

Signal Transduct Target Ther,2020,4;5:20.

PubMed: 32195002 ( click the link to review the publication )

Mol Ther Oncolytics,2020,30;17:169-179.

PubMed: 32346607 ( click the link to review the publication )

Cell Chem Biol,2020,20;27(2):197-205.e6.

PubMed: 31734178 ( click the link to review the publication )

Cell Chem Biol,2020,16;27(1):94-104.e5.

PubMed: 31902676 ( click the link to review the publication )

Antimicrob Agents Chemother,2020,4;AAC.02523-19.

PubMed: 32366713 ( click the link to review the publication )

Toxicol Sci,2020,1;174(2):218-240.

PubMed: 32040181 ( click the link to review the publication )

Int J Mol Sci,2020,18;21(8):2825.

PubMed: 32325639 ( click the link to review the publication )

Sci Rep,2020,24;10(1):5318.

PubMed: 32210281 ( click the link to review the publication )

J Biol Chem,2020,27;jbc.RA120.012981.

PubMed: 32461254 ( click the link to review the publication )

Breast Cancer Res Treat,2020,179(2):337-347.

PubMed: 31655920 ( click the link to review the publication )

PLoS One,2020,15(1):e0228189

PubMed: 31999754 ( click the link to review the publication )

bioRxiv,2020,doi:10.1101/2020.05.26.117770

PubMed: No ( click the link to review the publication )

J Allergy Clin Immunol,2020,21;S0091-6749(20)30259-1.

PubMed: 32088305 ( click the link to review the publication )

Genome Biol,2019,20(1):253

PubMed: 31771620 ( click the link to review the publication )

Sci Adv,2019,5(6):eaav9784

PubMed: 31249867 ( click the link to review the publication )
Cell Rep,2019,5;26(6):1544-1556.e8.

PubMed: 30726737 ( click the link to review the publication )

Neuropsychopharmacology,2019,10.1038/s41386-018-0266-7

PubMed: 30518933 ( click the link to review the publication )

Cancers (Basel),2019,30;11(2):156.

PubMed: 30704052 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):37

PubMed: 30845991 ( click the link to review the publication )

Cell Chem Biol,2019,21;26(2):235-243.e5.

PubMed: 30527999 ( click the link to review the publication )

Neurobiol Aging,2019,76:24-34

PubMed: 30640040 ( click the link to review the publication )

Cancer Gene Ther,2019,10.1038/s41417-019-0127-5

PubMed: 31383953 ( click the link to review the publication )

Stem Cells Int,2019,2019:3435901

PubMed: 31871467 ( click the link to review the publication )

Cancer Manag Res,2019,11:8391-8405

PubMed: 31571995 ( click the link to review the publication )

Breast Cancer Res Treat,2019,10.1007/s10549-019-05504-5

PubMed: 31784862 ( click the link to review the publication )

Acta Pharmacol Sin,2019,10.1038/s41401-019-0246-4

PubMed: 31197246 ( click the link to review the publication )

Cell Signal,2019,67:109508

PubMed: 31866490 ( click the link to review the publication )

Virology,2019,541:41-51

PubMed: 31826845 ( click the link to review the publication )

Int J Parasitol Drugs Drug Resist,2019,10:28-37.

PubMed: 31015150 ( click the link to review the publication )

J Med Virol,2019,91(8):1440-1447.

PubMed: 30900754 ( click the link to review the publication )

Bioengineered,2019,10(1):98-107

PubMed: 31023186 ( click the link to review the publication )

Kaohsiung J Med Sci,2019,10.1002/kjm2.12051

PubMed: 30896891 ( click the link to review the publication )

bioRxiv,2019,doi:10.1101/748129

PubMed: no ( click the link to review the publication )

Nat Commun,2018,9(1):1655

PubMed: 29695808 ( click the link to review the publication )

Cell Rep,2018,22(5):1185-1199

PubMed: 29386107 ( click the link to review the publication )

EBioMedicine,2018,28:80-89.

PubMed: 29396295 ( click the link to review the publication )

Cancer Sci,2018,109(4):1220-1229

PubMed: 29453896 ( click the link to review the publication )

Sci Rep,2018,8(1):13106

PubMed: 30166612 ( click the link to review the publication )

Sci Rep,2018,21;8(1):14178.

PubMed: 30242186 ( click the link to review the publication )
J Cell Physiol,2018,233(1):422-433

PubMed: 28294327 ( click the link to review the publication )

Oncotarget,2018,9(57):31018-31031

PubMed: 30123424 ( click the link to review the publication )

Methods Mol Biol,2018,1795:203-221.

PubMed: 29846930 ( click the link to review the publication )

Nat Commun,2017,17;8:16078.

PubMed: 28714472 ( click the link to review the publication )

Lab Chip,2017,31;17(3):511-520.

PubMed: 28092382 ( click the link to review the publication )

Anal Chem,2017,89(12):6678-6685

PubMed: 28520400 ( click the link to review the publication )

Antimicrob Agents Chemother,2017,e01674-17

PubMed: 29061736 ( click the link to review the publication )

Apoptosis,2017,22(12):1564-1577

PubMed: 29058102 ( click the link to review the publication )

PLoS One,2017,5;12(1):e0169407.

PubMed: 28056055 ( click the link to review the publication )

Parasitol Res,2017,116(10):2619-2626.

PubMed: 28776226 ( click the link to review the publication )

Biol Pharm Bull,2017,40(8):1289-1298.

PubMed: 28769010 ( click the link to review the publication )

Pharmacol Res,2016,113(Pt A):216-227

PubMed: 27543462 ( click the link to review the publication )

Biogerontology,2016,17(5-6):907-920.

PubMed: 27484416 ( click the link to review the publication )

PLoS One,2016,11(2):e0149848

PubMed: 26919709 ( click the link to review the publication )

Sensors (Basel),2016,16(3)

PubMed: 26999137 ( click the link to review the publication )

Database (Oxford),2016,7;2016:baw041.

PubMed: 27055828 ( click the link to review the publication )

Genome Biol,2015,19;16(1):127.

PubMed: 26084335 ( click the link to review the publication )

Clin Cancer Res,2015,21(5):1172-82

PubMed: 25549722 ( click the link to review the publication )

Biosens Bioelectron,2015,68:699-704

PubMed: 25668591 ( click the link to review the publication )

Cancer Discov,2015,5(2):154-67.

PubMed: 25501949 ( click the link to review the publication )

Mol Cancer Ther,2015,14(5):1213-23

PubMed: 25777964 ( click the link to review the publication )

Cell Cycle,2015,14(1):109-22

PubMed: 25602521 ( click the link to review the publication )

PLoS One,2015,10(11):e0142655

PubMed: 26569102 ( click the link to review the publication )

Oncotarget,2015,6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )
Head Neck,2015,37(12):1722-32

PubMed: 24986420 ( click the link to review the publication )

Mol Cancer Res,2014,12(5):703-13

PubMed: 24554781 ( click the link to review the publication )

Oncotarget,2014,5(15):6512-25

PubMed: 25156567 ( click the link to review the publication )

Curr Protoc Chem Biol,2014,4:177-191

PubMed: 26705509 ( click the link to review the publication )

Selleck化合物ライブラリー使用例

肝癌研究におけるGPCR Compound Libraryの使用例（当文献はNature (IF=43)に掲載され、研究期間は約15ヶ月です）：
Nature.2019;574(7777):268-272
大腸癌研究におけるKinase Inhibitor Library の使用例（当文献はNature Communications (IF=11)に掲載され、研究期間は約8ヶ月です）：
Nat Commun. 2019 16;10(1):2197
抗ウイルス研究におけるFDA-approved Drug Libraryの使用例（当文献はCell Research (IF=17)に掲載され、研究期間は約13ヶ月です）：
Cell Res. 2019;29(9):739-753
代謝研究におけるFDA-approved Drug Library使用例（当文献はMovement Disorders (IF=8)に掲載され、研究期間は約10ヶ月です）：
Mov Disord. 2019;34(3):323-334
白血病研究におけるEpigenetics Compound Libraryの使用例（当文献は Blood (IF=16)に掲載され、研究期間は約16ヶ月です）：
Blood. 2019 17;134(16):1323-1336
癌免疫研究におけるInhibitor Libraryの使用例（当文献はCancer Immunol Res (IF=8.6)に掲載され、研究期間は約12ヶ月です）：
Cancer Immunol Res.2017;5(9):790-803

製品特性＆メリット

・アポトーシス研究に使用する943種類の低分子ライブラリーです。

・Bcl-2、カスパーゼ、p53、TNFα、Mdm2、survinなどを標的にしています。

・構造的に多様で、薬効および細胞透過性が確認されています。

・詳しい構造説明と、お客様からのレビューなど豊富な情報があります。

・NMRとHPLC検査で製品の高純度を保証しています。

製品詳細情報

調合：	873 compounds pre-dissolved in 10mM DMSO, 42 compounds pre-dissolved in 10mM water, 27 compounds pre-dissolved in 2mM DMSO and 1 compounds pre-dissolved in 2mM water
ケース：	96/384 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
安定性：	12 months -20°Cin DMSO
安定性：	24 months -80°Cin DMSO
出荷方式：	ブルーアイス物流
包装：	不活性ガス（Inert gas）

Apoptosis Compound Library组成

HTS パートナ

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研究分野別

製品類型