Highly Selective Inhibitor Library

目录号 L3500

A unique collection of 312 validated bioactive compounds covering over 119 targets.

サイズ 価格(税別)  
予めDMSOまたは水に溶解しています
741400
1363800
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セレックの化合物ライブラリーはCOVID19研究に貢献しています

(日本)国立感染症研究所はセレックのFDA承認化合物を用いてスクリニーング実験を行い、研究から僅か3ヶ月以内にCOVID19
の治療薬候補を見出しました。本研究成果はBioRxivにて発表されました。doi: 10.1101/2020.04.14.039925。

お気に入りの分子或いは調達サービスにより、分子ライブラリーをカスタマイズします。
お客様自身のニーズを満たすために、弊社の製品を数量、状態（乾燥状態/固体或いはDMSO）等で選択できます。

Highly Selective Inhibitor Library内容

Download theHighly Selective Inhibitor Library - XLSX
Download theHighly Selective Inhibitor Library - SDF
Download the Compound Library Usage Instructions- PDF

Selleckの分子ライブラリーが使用されている文献(90)

Selleck化合物ライブラリー使用例

  • 肝癌研究におけるGPCR Compound Libraryの使用例

    Nature.2019;574(7777):268-272

  • 大腸癌研究におけるKinase Inhibitor Library の使用例

    Nat Commun. 2019 16;10(1):2197

  • 抗ウイルス研究におけるFDA-approved Drug Libraryの使用例

    Cell Res. 2019;29(9):739-753

  • 代謝研究におけるFDA-approved Drug Library使用例

    Mov Disord. 2019;34(3):323-334

  • 白血病研究におけるEpigenetics Compound Libraryの使用例

    Blood. 2019 17;134(16):1323-1336

  • 癌免疫研究におけるInhibitor Libraryの使用例

    Cancer Immunol Res.2017;5(9):790-803

製品特性＆メリット

・生物活性が確認されている、312種類のターゲット選択化合物ライブラリーです。

・それぞれの化合物はターゲット分子との相互作用能に基づいて選別されています。そのため、オフ・ターゲット作用は最小限に抑えられています。

・非メインターゲットに比べて選択性は100倍以上高いです。

・PI3K/Akt、MAPK、PTK、JAK、アポトーシスなど広範な経路を標的にしています。

・ターゲット分子を選別するためのツールとなります。

・構造的に多様で、薬効および細胞透過性が確認されています。

・詳しい構造説明と、お客様からのレビューなど豊富な情報があります。

・NMRとHPLC検査で製品の高純度を保証しています。

製品詳細情報

調合： 292 compounds pre-dissolved in 10mM DMSO, 5 compounds pre-dissolved in 10mM water and 15 compounds pre-dissolved in 2mM DMSO
ケース： 96/384 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
安定性： in DMSO
in DMSO
出荷方式： ブルーアイス物流
包装： 不活性ガス（Inert gas）

Highly Selective Inhibitor Library组成

HTS パートナ

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