| 製品コード |
製品名 |
製品説明 |
| P1151 |
Difelikefalin |
Difelikefalin (CR-845, FE-202845), a peripherally restricted and selective agonist of kappa opioid receptor (KOR), produces anti-inflammatory effects and has the potential in modulating pruritus in conditions such as chronic kidney disease. |
| E0524 |
Spinosad |
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. |
| E0525 |
Colistin |
Colistin, a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane. |
| E0528 |
Flecainide |
Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation. |
| E0530 |
Prednicarbate |
Prednicarbate (Dermatop) is a medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions. |
| E0527 |
Norgestimate |
Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. |
| E2516 |
Doxorubicin |
Adriamycin (Doxorubicin, Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent, inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication, and induces apoptosis, also inhibits human DNA topoisomerase I with an IC50 of 0.8 μM. |
| E2841 |
Sacituzumab govitecan |
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38, showing anticancer activity. |
| E0529 |
Metipranolol |
Metipranolol (Betamann) is potent β-adrenergic receptor antagonist, possessing the beta-blocking potencies (pA2) of 8.3, 8.4 at guinea pig atrial β1-adrenoceptor and β2-adrenoceptor of the rat uterus, respectively, also is a potent displacer of 3H-DHA binding, ligand concentration 0.7 nM, possessing a Ki value of 39 ± 24 nM. |
| S3562 |
Deserpidine |
Deserpidine (Harmonyl), an alkaloid isolated from the roots of Rauwolfia canescens, is a competitive angiotensin converting enzyme (ACE) inhibitor, also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex. |
| E0815 |
Rilpivirine Hydrochloride |
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. |
| P1111 |
Tesamorelin |
Tesamorelin, is a synthetic growth-hormone-releasing hormone (GHRH) analogue used clinically for the treatment of HIV-associated lipodystrophy (dysfunctional fat deposition). |
| E2665 |
Tafenoquine |
Tafenoquine (WR 238605) is an 8-aminoquinoline, used as an anti-malarial prophylactic agent. |
| E0938 |
Brincidofovir |
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438) with long-acting antiviral effect, shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. |
| E0939 |
Insulin Degludec |
Insulin degludec is an acylated basal insulin with a unique mechanism of protracted absorption involving the formation of a depot of soluble multihexamer chains after subcutaneous injection, shows a very long duration of action, with a half-life exceeding 25 h in PK/PD studies. |
| S2089 |
Fenoldopam |
Fenoldopam (SKF 82526) is a selective dopamine-1 (DA1) receptor agonist with natriuretic/diuretic properties with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells, which is more potent than DA . |
| S8886 |
PT2977 |
PT2977 (Belzutifan, MK-6482), an orally active and selective HIF-2α inhibitor, increases potency and improves pharmacokinetic profile, providing a potential treatment for clear cell renal cell carcinoma (ccRCC). |
| E0502 |
Metrizoic acid |
Metrizoic acid is a diagnostic radiopaque. The mechanism of action of metrizoic acid is as a X-Ray contrast activity. |
| E0178 |
Cysteamine bitartrate |
Cysteamine bitartrate (Mercaptamine bitartrate) is an FDA-approved cystine-depleting aminothiol agent for the treatment of nephropathic cystinosis to decrease accumulation of lysosomal cystine by engaging in disulfide exchange. In addition, cysteamine bitartrate has antioxidant properties. |
| E0500 |
Firocoxib (ML 1785713) |
Firocoxib (ML 1785713) is a cyclooxygenase (COX)-2 inhibitor and a nonsteroidal anti-inflammatory drug. In vitro firocoxib inhibits COX-1 and COX-2 with an IC50 of 7.5 mM and 0.13 mM respectively in feline blood. |
