| 製品コード |
製品名 |
製品説明 |
| S5326 |
Dolasetron |
Dolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist. It has minimal activity at other known serotonin receptors, and has low affinity for dopamine receptors. |
| S1646 |
Ketorolac |
Ketorolac (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. |
| S5399 |
Chlorprothixene hydrochloride |
Chlorprothixene HCl is the hydrochloride salt form of chlorprothixene, a typical antipsychotic drug of the thioxanthene (tricyclic) class. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.
|
| S5392 |
Mepivacaine |
Mepivacaine is a local anesthetic indicated for infiltration, nerve block, and epidural anesthesia. |
| S5416 |
Metyrapone |
Metyrapone is an inhibitor of the enzyme steroid 11-beta-monooxygenase that inhibits adrenal steroid synthesis. |
| S1021 |
Dasatinib |
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. |
| S1378 |
Ruxolitinib (INCB018424) |
Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. |
| S4642 |
Dolutegravir Sodium |
Dolutegravir is a HIV integrase inhibitor with IC50 of 2.7 nM. |
| S1150 |
Paclitaxel |
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. |
| S1208 |
Doxorubicin (Adriamycin) HCl |
Doxorubicin (Adriamycin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis in tumor cells. |
| S1261 |
Celecoxib |
Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM in Sf9 cells. |
| S1648 |
Cytarabine |
Cytarabine is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. |
| S5278 |
Tedizolid (TR-700) |
Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria. |
| S5238 |
Solifenacin (YM905) |
Solifenacin (YM905) is a competitive muscarinic receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle. |
| S5701 |
Alvimopan dihydrate (LY246736 dihydrate) |
Alvimopan (LY-246736) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors. |
| S9500 |
Valbenazine tosylate |
Valbenazine tosylate is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM). |
| S4848 |
Dalbavancin |
Dalbavancin is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci. |
| S5737 |
Diclofenac Epolamine |
Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. |
| S5674 |
Lodoxamide Tromethamine |
Lodoxamide Tromethamine is the tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity. |
| S5254 |
Dasatinib hydrochloride |
Dasatinib hydrochloride is the hydrochloride salt form of dasatinib, an inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. |
