カルシウムチャネル

信号経路図

研究分野

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1356 Levetiracetam 34 mg/mL 34 mg/mL 34 mg/mL
S1813 Amlodipine Besylate <1 mg/mL 113 mg/mL 14 mg/mL
S1293 Cilnidipine <1 mg/mL 99 mg/mL 15 mg/mL
S1811 Amiloride HCl 6 mg/mL 53 mg/mL 5 mg/mL
S1425 Ranolazine 2HCl 100 mg/mL 100 mg/mL <1 mg/mL
S8380 YM-58483 (BTP2) <1 mg/mL 84 mg/mL 84 mg/mL
S4727 Cinnarizine <1 mg/mL 73 mg/mL <1 mg/mL
S4202 Verapamil HCl 50 mg/mL 98 mg/mL 12 mg/mL
S2482 Manidipine 2HCl <1 mg/mL 21 mg/mL <1 mg/mL
S1799 Ranolazine <1 mg/mL 86 mg/mL 20 mg/mL
S1662 Isradipine <1 mg/mL 74 mg/mL 74 mg/mL
S1905 Amlodipine <1 mg/mL 82 mg/mL 82 mg/mL
S1885 Felodipine <1 mg/mL 77 mg/mL 72 mg/mL
S2481 Manidipine <1 mg/mL 122 mg/mL 3 mg/mL
S1748 Nisoldipine <1 mg/mL 77 mg/mL 60 mg/mL
S1747 Nimodipine <1 mg/mL 84 mg/mL 84 mg/mL
S2535 Econazole nitrate <1 mg/mL 89 mg/mL 5 mg/mL
S2721 Nilvadipine <1 mg/mL 77 mg/mL 33 mg/mL
S1994 Lacidipine <1 mg/mL 91 mg/mL 22 mg/mL
S2114 Dronedarone HCl <1 mg/mL 80 mg/mL 40 mg/mL
S2446 Levosimendan <1 mg/mL 56 mg/mL <1 mg/mL
S4181 Nicardipine HCl <1 mg/mL 100 mg/mL <1 mg/mL
S1808 Nifedipine <1 mg/mL 69 mg/mL 15 mg/mL
S2080 Clevidipine Butyrate <1 mg/mL 91 mg/mL 3 mg/mL
S2017 Benidipine HCl <1 mg/mL 8 mg/mL <1 mg/mL
S2918 HC-030031 <1 mg/mL 32 mg/mL <1 mg/mL
S2030 Flunarizine 2HCl <1 mg/mL 5 mg/mL 3 mg/mL
S2491 Nitrendipine <1 mg/mL 72 mg/mL <1 mg/mL
S2050 Strontium Ranelate <1 mg/mL <1 mg/mL <1 mg/mL
S3053 Azelnidipine <1 mg/mL 117 mg/mL 7 mg/mL
S2573 Tetracaine HCl 60 mg/mL 60 mg/mL 30 mg/mL
S1911 Disodium Cromoglycate 2 mg/mL <1 mg/mL <1 mg/mL
S1865 Diltiazem HCl 90 mg/mL 90 mg/mL 4 mg/mL
S7999 SKF96365 80 mg/mL 80 mg/mL 80 mg/mL
S3045 Cinepazide maleate 107 mg/mL 107 mg/mL <1 mg/mL
S8073 Optovin <1 mg/mL 63 mg/mL <1 mg/mL
S4626 Ethosuximide 28 mg/mL 28 mg/mL 28 mg/mL
S4597 Lercanidipine (hydrochloride) <1 mg/mL 66 mg/mL 1 mg/mL
S2403 Tetrandrine <1 mg/mL 1 mg/mL 2 mg/mL
S4084 Lomerizine 2HCl <1 mg/mL 100 mg/mL 52 mg/mL
S4648 Dantrolene sodium hemiheptahydrate <1 mg/mL 14 mg/mL <1 mg/mL
S7924 Bay K 8644 <1 mg/mL 71 mg/mL 71 mg/mL
S2415 Astragaloside A <1 mg/mL 100 mg/mL <1 mg/mL
S4209 Chlorocresol <1 mg/mL 29 mg/mL 29 mg/mL
製品コード 製品説明 文献中の使用例 お客様のフィードバック
S1356

Levetiracetam

Levetiracetam is an antiepileptic compound.

S1813

Amlodipine Besylate

Amlodipine Besylate is a long-acting calcium channel blocker with an IC50 of 1.9 nM.

S1293

Cilnidipine

Cilnidipine is a calcium channel blocker.

S1811

Amiloride HCl

Amiloride hydrochloride(Midamor), a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells.

S1425

Ranolazine 2HCl

Ranolazine 2HCl, is an antianginal medication.

S8380

YM-58483 (BTP2)

S4727

Cinnarizine

S4202

Verapamil HCl

Verapamil HCl、クラスIV抗不整脈剤であるL型カルシウムチャネル遮断薬です。

S2482

Manidipine 2HCl

Manidipine 2HCl は、Ca2+現在 に賛成のカルシウムチャネル・ブロッカーであるManidipineのHCl塩の形で、IC50 が2.6 nMです。

S1799

Ranolazine

Ranolazine(Ranexa) is an antianginal medication.

S1662

Isradipine

Isradipine is a calcium channel blocker with an IC50 of 34±8 μM.

S1905

Amlodipine

Amlodipine is a long-acting calcium channel blocker with an IC50 of 1.9 nM.

S1885

Felodipine

Felodipine は<がすする選択的なL-タイプCaが、>2+<で/すする> チャンネル・ブロッカー、IC50 が0.15 nMになる。

S2481

Manidipine

Manidipine is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.

S1748

Nisoldipine

Nisoldipine (Sular)は特定L型CaV1.2カルシウムチャネル遮断剤、 IC50 が 10 nMになる.

S1747

Nimodipine

Nimodipineは一種のジヒドロピリジン カルシウム チャネル( dihydropyridine calcium channel)阻害剤で、一種の自食阻害剤ですが、高血圧の治療に使用されます。

S2721

Nilvadipine

Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.

S1994

Lacidipine

Lacidipine is a L-type calcium channel blocker.

S2114

Dronedarone HCl

Dronedarone HCl is a therapy for the treatment of patients with paroxysmal and persistent atrial fibrillation or atrial flutter.

S4181

Nicardipine HCl

Nicardipine HClは著しい血管拡張作用を有するジヒドロピリジンカルシウムチャネル遮断薬です。

S1808

Nifedipine

Nifedipine(Adalat), a potent vasodilator agent with calcium antagonistic action.

S2080

Clevidipine Butyrate

Clevidipine Butyrate is a dihydropyridine calcium channel blocker use as agent for the reduction of blood pressure.

S2017

Benidipine HCl

Benidipine HCl is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.

S2918

HC-030031

HC-030031は、選択的なTRPA1 AITCとホルマリンによって引き起こされたチャンネル・ブロッカー カルシウム流入で、IC50 がそれぞれ 6.2 μM と5.3 μMです。

S2030

Flunarizine 2HCl

Flunarizine 2HCl is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.

S2491

Nitrendipine

Nitrendipineは一種のジヒドロピリジン カルシウム チャネル( dihydropyridine calcium channel)阻害剤で、IC50値が95nMです。

S3053

Azelnidipine

Azelnidipine is a dihydropyridine calcium channel blocker.

S2573

Tetracaine HCl

Tetracaine HCl is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.

S1865

Diltiazem HCl

Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.

S7999

SKF96365

S3045

Cinepazide maleate

Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.

S4626

Ethosuximide

S4597

Lercanidipine (hydrochloride)

S2403

Tetrandrine

Tetrandrine is a calcium channel blocker with an IC50 of 38.23± 25.77 μM.

S4084

Lomerizine 2HCl

Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.

S4648

Dantrolene sodium hemiheptahydrate

S2535

Econazole nitrate

Econazole nitrate (Spectazole) is an imidazole class antifungal medication.

S2415

Astragaloside A

Astragaloside A is a pure small molecular compound isolated from Radix Astragali and is commonly used in the treatment of degenerative bone diseases such as osteoporosis.

S2446

Levosimendan

Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC).

S1911

Disodium Cromoglycate

Disodium Cromoglycate is an antiallergic drug with IC50 of 39 μg/mL.

S2050

Strontium Ranelate

Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.

S8073

Optovin

Optovin is a reversible photoactivated TRPA1 activator.

S7924

Bay K 8644

S4209

Chlorocresol

Chlorocresol is an activator of ryanodine receptor.

製品コード 製品説明 文献中の使用例 お客様のフィードバック
S1356

Levetiracetam

Levetiracetam is an antiepileptic compound.

S1813

Amlodipine Besylate

Amlodipine Besylate is a long-acting calcium channel blocker with an IC50 of 1.9 nM.

S1293

Cilnidipine

Cilnidipine is a calcium channel blocker.

S1811

Amiloride HCl

Amiloride hydrochloride(Midamor), a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells.

S1425

Ranolazine 2HCl

Ranolazine 2HCl, is an antianginal medication.

S8380

YM-58483 (BTP2)

S4727

Cinnarizine

S4202

Verapamil HCl

Verapamil HCl、クラスIV抗不整脈剤であるL型カルシウムチャネル遮断薬です。

S2482

Manidipine 2HCl

Manidipine 2HCl は、Ca2+現在 に賛成のカルシウムチャネル・ブロッカーであるManidipineのHCl塩の形で、IC50 が2.6 nMです。

S1799

Ranolazine

Ranolazine(Ranexa) is an antianginal medication.

S1662

Isradipine

Isradipine is a calcium channel blocker with an IC50 of 34±8 μM.

S1905

Amlodipine

Amlodipine is a long-acting calcium channel blocker with an IC50 of 1.9 nM.

S1885

Felodipine

Felodipine は<がすする選択的なL-タイプCaが、>2+<で/すする> チャンネル・ブロッカー、IC50 が0.15 nMになる。

S2481

Manidipine

Manidipine is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.

S1748

Nisoldipine

Nisoldipine (Sular)は特定L型CaV1.2カルシウムチャネル遮断剤、 IC50 が 10 nMになる.

S1747

Nimodipine

Nimodipineは一種のジヒドロピリジン カルシウム チャネル( dihydropyridine calcium channel)阻害剤で、一種の自食阻害剤ですが、高血圧の治療に使用されます。

S2721

Nilvadipine

Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.

S1994

Lacidipine

Lacidipine is a L-type calcium channel blocker.

S2114

Dronedarone HCl

Dronedarone HCl is a therapy for the treatment of patients with paroxysmal and persistent atrial fibrillation or atrial flutter.

S4181

Nicardipine HCl

Nicardipine HClは著しい血管拡張作用を有するジヒドロピリジンカルシウムチャネル遮断薬です。

S1808

Nifedipine

Nifedipine(Adalat), a potent vasodilator agent with calcium antagonistic action.

S2080

Clevidipine Butyrate

Clevidipine Butyrate is a dihydropyridine calcium channel blocker use as agent for the reduction of blood pressure.

S2017

Benidipine HCl

Benidipine HCl is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.

S2918

HC-030031

HC-030031は、選択的なTRPA1 AITCとホルマリンによって引き起こされたチャンネル・ブロッカー カルシウム流入で、IC50 がそれぞれ 6.2 μM と5.3 μMです。

S2030

Flunarizine 2HCl

Flunarizine 2HCl is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.

S2491

Nitrendipine

Nitrendipineは一種のジヒドロピリジン カルシウム チャネル( dihydropyridine calcium channel)阻害剤で、IC50値が95nMです。

S3053

Azelnidipine

Azelnidipine is a dihydropyridine calcium channel blocker.

S2573

Tetracaine HCl

Tetracaine HCl is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.

S1865

Diltiazem HCl

Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.

S7999

SKF96365

S3045

Cinepazide maleate

Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.

S4626

Ethosuximide

S4597

Lercanidipine (hydrochloride)

S2403

Tetrandrine

Tetrandrine is a calcium channel blocker with an IC50 of 38.23± 25.77 μM.

S4084

Lomerizine 2HCl

Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.

S4648

Dantrolene sodium hemiheptahydrate

製品コード 製品説明 文献中の使用例 お客様のフィードバック
S2050

Strontium Ranelate

Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.

S8073

Optovin

Optovin is a reversible photoactivated TRPA1 activator.

S7924

Bay K 8644

S4209

Chlorocresol

Chlorocresol is an activator of ryanodine receptor.

製品コード 製品説明 文献中の使用例 お客様のフィードバック
S2535

Econazole nitrate

Econazole nitrate (Spectazole) is an imidazole class antifungal medication.

S2415

Astragaloside A

Astragaloside A is a pure small molecular compound isolated from Radix Astragali and is commonly used in the treatment of degenerative bone diseases such as osteoporosis.

製品コード 製品説明 文献中の使用例 お客様のフィードバック
S2446

Levosimendan

Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC).

2017, 146:76-85

S1911

Disodium Cromoglycate

Disodium Cromoglycate is an antiallergic drug with IC50 of 39 μg/mL.