Vorinostat (SAHA, MK0683)

製品コードS1047 別名:SAHA, MK0683, suberoylanilide hydroxamic acid

Vorinostat (SAHA, MK0683)化学構造

分子量(MW):264.3

Vorinostat (suberoylanilide hydroxamic acid, SAHA)は一種のHDAC阻害剤で、無細胞試験でIC50値が約10 nMです。

サイズ 価格 在庫  
JPY 31706.00 あり
JPY 24402.00 あり
JPY 36520.00 あり

文献中の引用(100)

カスタマーフィードバック(20)

  • Differential effects of HDAC inhibitors on histone and tubulin acetylation. Immunofluorescence analysis of histone H3 (K9ac/K14ac) and tubulin acetylation in HeLa cells treated for 4 h with vehicle, SAHA (10 μM), tacedinaline (50 μM), PCI-24781 (20 μM. (a) Mapping of histone acetylation in K562 cells treated with HDAC inhibitors by LC-MS/MS. Cells were treated with TSA (10 μM), SAHA (5 μM), PCI-24781 (2 μM), tacedinaline (50 μM) for 6 h. Histones were extracted from cells and acetylated peptides were quantified after isobaric tagging.

    Nat Biotechnol 2011 29, 255-265. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Activity of vorinostat in Jurkat and Peer T-ALL cell lines in an MTT cell viability assay. Cells were treated with increasing drug concentrations for 72 h. The data are plotted as the mean % of DMSO-treated control cells against the corresponding drug concentration. The error bars are the standard error. For each drug and cell line, 3-4 independent experiments were performed with 6 replicates at each drug concentration.

    Nature 2011 471, 235-9. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Western blot analysis of histone H3 acetylation in the spleen of untreated and vorinostat-treated hNF-E2 tg mice (n = 4 of each genotype).

    J Exp Med 2012 209, 35-50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    SAHA down-regulates c-FLIP expression and increases the sensitivity of CaP cells to undergo apoptosis in the presence of bicalutamide (A) Bar graph illustrating the sub-G0/G1 cell population in 22Rv1 (left panel) and LNCaP (right panel) cells in the absence and presence of 10μM bicalutamide, administered as a single agent or in ombination with increasing concentrations of the HDAC inhibitor, SAHA. (B) Immunoblots demonstrating the single agent activity of bicalutamide or SAHA, or effect upon their combined administration on the expression of c-FLIP and/or the processing of PARP. Equal protein loading was confirmed by GAPDH. (C) Bar graph illustrating the effect of bicalutamide and SAHA upon the induction of caspase-8 or caspase-3/7 activity in 22Rv1 cells (left panel) and LNCaP cells (right panel). (D) Immunoblots characterizing the impact of SAHA and/or bicalutamide upon the induction of PARP cleavage, in the absence or presence of the pan-caspase inhibitor, ZIETD. ZIETD was incubated with the cells for 12 h prior to the experiment. All data points shown in (A) and (C) represent the mean ± S.E.M. value, calculated from four independent experiments.

    Clin Cancer Res 2012 18, 3822-33. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Analyses of efficacy, potency and IC50 of HDAC inhibitors point toward HDACs 1–3 as relevant candidates for beta cell protection. Ranking and raw data on ITF drugs (Table 3) and commercial HDAC inhibitors (Table 4) underlying the heat maps of Fig. 1 (A and B). The HDAC inhibitor compounds were tested using a HDAC activity kit and recombinant proteins to determine IC50 values on each individual HDAC (right part of the table). Each drug was further tested using Real-Time Cell Analysis (RTCA) to score their maximal effective concentration (ECmax) as well as the corresponding rescue percentage of cytokine treated INS-1 cells. The drugs were ranked according to % rescue. * DMSO alone controls were included in each experiment, but not shown here. The results indicate that the highest concentrations of DMSO used here (1:1,000) were slightly potentiating the proliferation of the cells. The effects observed in this group of compounds were ascribed to the DMSO.?

    Diabetologia 2012 55, 2421-2431. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Proliferation o f HT29 and HCT116 cells after 48 h of butyrate or SAHA treatment. Proliferation measurements using the xCEL Ligence RTCA DP instrument (Roche) in cells treated with increasing doses of butyrate or SAHA, compared with control medium cells (0) (*P < 0.05). The mean ?SEM of three cell culture replicates is shown.

    Mol Carcinog 2012 52, 459-74. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Suberoylanilide hydroxyamic acid (SAHA) preserves CFP (+) expression in mouse optic nerves (MONs) from older mice. (a) CFP (+) mitochondria were longer and thicker in MONs from 12-month-old Thy-1 CFP mice (inset; scale bar = 2 μm). Oxygen–glucose deprivation (OGD) consistently reduced CFP pixel intensity in 12-month-old MONs despite longer and brighter CFP ( +) mitochondria (yellow arrows). (b) Blockade of AMPA/kain ate receptors with NBQX (30 μM), or pan-Histone deacetylase (HDAC) inhibition with SAHA (5 μM), effectively preserved CFP pixel intensity during OGD. The preservation of CFP (+) mitochondria correlates with protection of the CAP area during OGD and profound recovery.

    J Neurochem 2012 123 Suppl 2, 108-15. Vorinostat (SAHA, MK0683) purchased from Selleck.

    D and E, Regression of IL-13Ra 2-negative pancreatic tumors treated with SAHA and/or IL-13-PE. Mice were treated daily with i.p. injection of SAHA (25 mg/kg) from day 4 after tumor implantation for two weeks followed by i.t. injection of IL-13-PE (100 μ g/kg) from day 5 for two weeks. F and G, Regression of IL-13Ra 2-posotive pancreatic tumors (HS766T and MIA-PaCa2) treated with SAHA and/or IL-13-PE. The schedule of treatment was similar as in panel D and E. Statistical significances are shown by *: P < 0.05,†: P < 0.001.

    J Transl Med 2011 9, 37. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • IL-13Rα2 expression is upregulated in pancreatic tumors but not in organs of mice after treatment with HDAC inhibi tor, SAHA. A, qRT-PCR of human IL-13Rα2 in implanted pancreatic tumors after SAHA and IL-13-PE treatment. Tumors were harvested next day after IL-13-PE treatment and total RNA extracted. Data shown is ratio of human IL-13Rα2/β-actin expression and multiplied by 1000 for convenience. Bars , SD of triplicate determinations. B, qRT-PCR of mouse IL-13Rα2 in mice organs after SAHA and IL-13-PE treatment. Tissues were harvested at the same time point as in panel A and total RNA extracted. Data shown is ratio of mouse IL-13Rα2/β-actin expression and multiplied by 100 for convenience. C, IHC of human IL-13Rα2 in implanted pancreatic tumors after SAHA and IL-13-PE treatment. D, IHC of mouse IL-13Rα2 in mice organs after SAHA and IL-13-PE treatment. Liver, brain, kidney, pancreas, lung and spleen were fixed for immunostaining of mouse IL-13Rα2 as visualized by Alexa555. Nucleus was counterstained by DAPI.

    J Transl Med 2011 9, 37. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Vorinostat inhibits the tumor growth. NOD ⁄ SCID-B2m-/-mice were injected s.c. with 1×106 MyLa2059 cells into both flanks. When the mice had developed established palpable tumors treatment was initiated (day 1). The mice received either vehicle (black line) or 60 mg ⁄ kg vorinostat (grey line) i.p. five days a week. In total, there were four mice in the group receiving vehicle and three mice in the group receiving vorinostat. The length and width of the tumors were measured continuously until the experiment was terminated on day 20 post treatment initiation. The tumor volume was calculated using the formula V = (a×b2)/2, where a defines the length (mm) and b the width (mm) of the tumor. The histogram shows the average tumor volume per flank ± SEM. * denotes a significant difference (P < 0.05) in the average tumor volume per flank between mice treated with vehicle and vorinostat at the given time-point both by using a one-tailed two samples test with Welch, scorrection and a Mann-Whitney U test.

     

     

    Exp Dermatol 2010 19, 1096-1102. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • SAHA induces the down-regulation of cFLIP expression and promotes TRAIL-mediated activation of a mitochondrial-operated apoptotic pathway. a BT-474 cells were treated as indicated in Fig. 1 and the cells were then harvested to analyse caspase-8, Bid, caspase-9, caspase-3 and PARP expression, using GAPDH as the protein loading control. b BT-474 cells were treated with SAHA for 8 h at the doses indicated and subsequently, the cells were harvested and the apoptosis-related proteins were analysed in western blots as described in the "Materials and Methods". The results shown are representative of at least three independent experiments

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Treatment with SAHA sensitizes breast cancer cells to TRAILinduced apoptosis. BT-474 and MDA-MB-231 cells were incubated for 8 h with SAHA at the doses indicated. After this time, TRAIL (500 ng/ml) was added to some of the cultures for an additional 15 h. Apoptosis was measured as the percentage of cells with subG1 DNA content as described in the "Materials and methods". The results show the mean and S.E.M. of three independent experiments

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • SAHA facilitates the Itch/AIP4-independent proteasomal degradation of cFLIP proteins in breast cancer cells. a BT-474 cells were treated with SAHA (5 μM) for 8 h in the presence or absence of the proteasome inhibitors MG132 or epoxomicin (at the doses indicated), and they were then harvested and the cFLIP content was analysed in western blots. b BT-474 cells were transfected with either the siRNA oligonucleotides targeting Itch/AIP4 or the non-targeting RNA oligonucleotide (scrambled) for 48 h as described in the "Materials and Methods". Subsequently, the cells were treated with SAHA (5 μM) for 8 h and then cFLIP and Itch/AIP4 expression was analysed in immunoblots

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

    cFLIP down-regulation following SAHA treatment is responsible for the sensitization of breast cancer cells to TRAIL. a BT-474 cells were transfected with either different siRNAs directed against the cFLIP isoforms or the non-targeting RNA oligonucleotide (scrambled) as described in the "Materials and Methods". After 24 h, the cells were treated with TRAIL (500 ng/ml) for a further 15 h and apoptosis was then measured as the percentage of cells with subG1 DNA content. The results show the mean and S.E.M. of three independent experiments. To verify protein knockdown, cells were harvested 24 h after transfection and the cFLIP levels were assessed in immunoblots. b. BT-474 cells overexpressing Cflipl (pBABE-FLIPL) or control cells (pBABE) were treated with SAHA for 8 h at the doses indicated. After this time, TRAIL (500 ng/ml) was added to some cultures for 15 h. Apoptosis was measured as the percentage of cells with subG1 DNA content and the results show the mean and range of two independent experiments. Western blots show the cFLIP levels after SAHA treatment in pBABE and pBABE-FLIPL cells.

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • (a) Western blot of whole cell extracts demonstrates SAHA and NaB treatment result in increased levels of acetylated histone H3 compared to vehicle controls. (b) Light micrographs of HDACi/vehicle treated cultures illustrate the paucity of neurospheres in HDACi-treated cultures. (c) Quantitative analysis confirms SAHA and NaB inhibit the formation of neurospheres (diameter ≥ 50 μm) and increase the prevalence of small cell clusters (≥ 4 cell, diameter < 50 μm). (d) Flow cytometry using LIVE/DEAD cell stain confirms SAHA and NaB are minimally toxic compared to vehicle controls (n = 3). Scale bar = 100 μm.

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    (a) EdU flow cytometry of live cell-gated adult mouse NSCs demonstrates SAHA (**p < 0.01) and NaB (***p < 0.001) significantly inhibit DNA synthesis. (b) Analysis of DNA content by flow cytometry reveals significant accumulation of adult mouse NSCs in G1phase of the cell cycle following SAHA (*p < 0.05) and NaB (*p < 0.05) treatment. (c) Correspondingly the proportion of cells in G2/M phase is significantly reduced following SAHA (*p < 0.05) and NaB (*p < 0.05) treatment. (d) Fluorescence micrographs of HDACi/vehicle treated adult NSCs pulse-labeled with EdU for flow cytometry. Scale bar = 50 μm. Statistical comparisons performed using one-way ANOVA with post hoc Newman-Keuls multiple comparison tests.

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • (a) Immunofluorescence labeling of NeuN, GFAP and Olig2 cell fate markers reveals reduced expression of GFAP (*p < 0.001) and Olig2 (*p < 0.05) in adult mouse NSCs treated with SAHA for 48 hours under proliferation culture conditions and then induced to differentiate for 14 days in culture (two-way ANOVA with Bonferroni post-tests). (b) Western blot of β-catenin protein in nuclear and cytoplasmic fractions of adult mouse NSCs treated with HDACi/vehicle control under proliferation culture conditions. Gapdh and lamin A/C blots are included as loading controls. (c) SAHA and NaB do not significantly alter nuclear/cytoplasmic levels of β-catenin in adult mouse NSCs. Histogram of β-catenin Western blot signal intensities normalized to loading controls (n = 4).

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Morphological changes and histone H3 phosphorylation of HB cells treated with a combination of VX-680 and SAHA. HUH6 and HepT1 were incubated with VX-680 (6 μM) and SAHA (0.5 μM). Nuclei diameter (a) and cell diameter (b) were determined 72 h later by DAPI staining and microscopy. Data represent mean±SD of the diameters from 20 cells in each experiment. (* Two-way ANOVA, Bonferroni test, p \0.05). c Western blot analysis on HUH6 and HepT1 cells were carried out with an anti-phospho-Histone H3 (Ser 10) antibody (p-H3) 24 h after incubation with VX-680 (10 μM), SAHA (0.2 μM) or a combination of both. Controls were left untreated. Western blot analysis showed a decrease in p–H3 after treatment with VX-680 ( lane 2 ) relative to controls ( lane 1 ) and an increase when SAHA was added ( lane 3 ). For the combination of VX-680 and SAHA (lane 4 ) no p-H3 was detected.

    Pediatr Surg Int 2012 28, 579-89. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Vorinostat promotes C2C12 differentiation.In the image, the red is the myotube indicating differentiation ,the blue is the nuclei.

     

     

    Dr. Akihiko Yoshimura of Akihiko Yoshimura. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Western blot analysis of Acetyl-H3 and H3. 0-20μM SAHA was added.

     

     

    Dr. Zhang of Tianjin Medical University. Vorinostat (SAHA, MK0683) purchased from Selleck.

製品安全説明書

HDAC阻害剤の選択性比較

生物活性

製品説明 Vorinostat (suberoylanilide hydroxamic acid, SAHA)は一種のHDAC阻害剤で、無細胞試験でIC50値が約10 nMです。
ターゲット
HDAC [1]
(Cell-free assay)
~10 nM
体外試験

Vorinostat inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively. Vorinostat also results in a marked hyperacetylation of histone H4. [1] Vorinostat inhibits the growth of three prostate cancer cell lines LNCaP, PC-3 and TSU-Pr1 at micromolar concentrations (2.5-7.5 μM), and induces dose-dependent cell death in LNCaP cells. [2] Vorinostat treatment in MCF-7 cells inhibits cell proliferation at an IC50 of 0.75 μM resulting in the accumulation of cells in the G1 and G2-M phase of the cell cycle. Vorinostat also induces differentiation in the estrogen receptor-negative cell line SKBr-3 and the retinoblastoma-negative cell line MDA-468. [3] Vorinostat treatment at 1 μM for 8 hours or more is sufficient to irreversibly induce apoptosis of human multiple myeloma (MM) cells. The gene expression profiles of Vorinostat treated MM cells are not hallmarked by global transcriptional activation, but by coordinated transcriptional changes of specific functional groups of genes such as cytokine-induced proliferative/survival signaling cascades, oncogenes-tumor suppressor genes, regulators of apoptosis, DNA synthesis-repair and cell cycle, and proteasome-ubiquitin function. [4]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
A20 NVvBOXd4U2mwYYPlJGF{e2G7 NIjRR2MyKGh? M2G1XmROW09? Mk\CZY51cS2KRFHDNUBi[3Srdnn0fUB4cXSqIFnDOVAhd2ZiMD6xNVIh|ryP NHTSXJMyOTl4MES4PS=>
Friend leukemic cell NVPRN3hGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUK1NEDPxE1? NXXGO|l{PzJiaB?= Mn\uSG1UVw>? NHflc2hKSzVyPUCuPVkh|ryP MUGxNlExQTlzMx?=
K562 M3jxTWtqdmG|ZTDBd5NigQ>? NWj0[4JxPiCq MXPEUXNQ MknGTY5pcWKrdHnvckBw\iCqdX3hckBpcXO2b37lJIRm[WOndInsZZNmKCivaYj0eZJmKG:oIFjERWMyKGGwZDDISGFEOilid3n0bEBKSzVyIH;mJFAvODFizszN MlniNVI1OTl|OEC=
HT1080 MoXXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3HTWlxPzJiaB?= NI\QOoxFVVOR NFHZUHBKSzVyPUKuOEDPxE1? MYSxNlI4ODF5NR?=
H1299 MmfHT4lv[XOnIFHzd4F6 MXuyNEBucW5? NGXWZm1FVVOR M4n5RmlvcGmkaYTvdpkh[WO2aY\peJkh[WejaX7zeEBJTEGFIHXufplu\SC5aYToJGlEPTBib3[gNE4yQTRizszN NIjMc4MyPDV{MUSyNi=>
H1299 NEm1TlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2OzOlczKGh? MWLEUXNQ NWrqSJNHUUN3ME23MlI1KM7:TR?= MWKxOFUzOTR{Mh?=
HeLa MXXLbY5ie2ViQYPzZZk> MoTwN|AhdWmw MknDTY5pcWKrdH;yfUBkd26lZX70doF1cW:wIHHnZYlve3RiaHnzeI9v\SCmZXHj[ZR6dGG|ZTD3bZRpKEmFNUCgc4YhOC5{ODFOwG0> MXGxOVYxOzl2OR?=
LOX-IMVI NGfEXohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1HBOlQ5KGh? M3\wO2lEPTB;MT6zJO69VQ>? M1HB[VE2PzF3NEew
NCI-H226 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXK0PEBp MornTWM2OD1{Lk[g{txO MoDjNVU4OTV2N{C=
RXF-631L NXnBSINZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGjFSnQ1QCCq MUPJR|UxRTJizszN NETPZWMyPTdzNUS3NC=>
SNB-78 Mm\oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmXNOFghcA>? Mle4TWM2OD1zNjFOwG0> MkXmNVU4OTV2N{C=
St-4 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvzOFghcA>? NHfiSGxKSzVyPUWuNkDPxE1? MYCxOVcyPTR5MB?=
ARP1 MmTBSpVv[3Srb36gRZN{[Xl? M3HMWlIh|ryP M3;pcVYhcA>? M1P2S2lv\HWldHnvckBw\iCSMkHXRWYyKGenbnWg[ZhxemW|c3nvci=> NETwV20yPDd|NEiwOi=>
CEM NXvRZ5F[U2mwYYPlJGF{e2G7 NWjYWYJsOSCq MmnySG1UVw>? NFjweo5KdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuN|Mh|ryP NIK3[HoyPjR{MEC2OC=>
HCT15 NFrsblNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUe0PEBp M4roRWdKPTB;MD64NkDPxE1? M4O0VlE3PzJ|MkK3
NCI-H23 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUTMeGNTPDhiaB?= NGDUSFRIUTVyPUCuPVIh|ryP NWnNT4JGOTZ5MkOyNlc>
GM15850 MWLLbY5ie2ViQYPzZZk> MVyyMlUh|ryP NUnFc|dEQTZiaB?= MUHEUXNQ NY\yUZI5UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFMhdHm|aX7lJFE1KGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l NF\ocFIyPjl{MUO2Oy=>
GM15850 M4rrSWtqdmG|ZTDBd5NigQ>? MojmNk42KM7:TR?= MkezPVYhcA>? M4\GdWROW09? MUXJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKNDDsfZNqdmViNTDhZ4V1gWyjdHnvckBw\iCIWF6g[4Vv\Q>? MUCxOlkzOTN4Nx?=
GM15850 M17tcGtqdmG|ZTDBd5NigQ>? NFf1WmozNjVizszN NUHkdo9jQTZiaB?= MkC5SG1UVw>? NX\JclRrUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFQhdHm|aX7lJFEzKGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l M3[yOVE3QTJzM{[3
GM15850 NFHqV21McW6jc3WgRZN{[Xl? NVHhToFPOi53IN88US=> NWLuSGE3QTZiaB?= NWXqSGk1TE2VTx?= M17XbGlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFizJIx6e2mwZTC5JIFk\XS7bHH0bY9vKG:oIF\YUkBo\W6n NEL2[o0yPjl{MUO2Oy=>
GM15850 NYnxN5RlU2mwYYPlJGF{e2G7 MXKyMlUh|ryP MVe5OkBp MXvEUXNQ NFjrfmNKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgPEBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= M{L0clE3QTJzM{[3
GM15850 MXTLbY5ie2ViQYPzZZk> MXiyMlUh|ryP M3zybVk3KGh? MoDESG1UVw>? NWD5RlAyUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFQhdHm|aX7lJFE3KGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l NV3FWWVrOTZ7MkGzOlc>
U937 M3qxdGZ2dmO2aX;uJGF{e2G7 NXnJc5A6PSEQvF2= M1nyVVI1KGh? M1jMOGROW09? MnG5R4VtdCCleXPs[UBienKnc4SgZpkh[WOldX31cIF1cW:wIHH0JHMwTzJxTTDwbIF{\Q>? MXOxO|AxPDdzOB?=
H661 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmewOFghcA>? NXO4emFlUUN3ME2xJO69VQ>? M4exeFE4OTV5MEC5
U937 NYf3[JVyTnWwY4Tpc44hSXO|YYm= MmnWOUDPxE1? MX2yOEBp M{XEXmROW09? MXLJcoNz\WG|ZTDpckBpcXO2b37lJGg{KGGlZYT5cIF1cW:w NGHHcpQyPzR2N{e1NC=>
U937 MoTsSpVv[3Srb36gRZN{[Xl? NVjtNG04OSEQvF2= NWWyV4ZCOjRiaB?= M{SwcGROW09? MoLNSYZn\WO2IH;uJIFteGijIIT1ZpVtcW5iYXPleJlt[XSrb36= Mn;CNVc1PDd5NUC=
RAW264.7 NULIenV5TnWwY4Tpc44hSXO|YYm= NX;jUmltOTBizszN M{HTN|I1cA>? NETEWlJ4[XSnch?= M{jEUmlvcGmkaYTpc44hd2ZiTGDTMZN1cW23bHH0[YQhXE6IYXzwbIEheHKxZIXjeIlwdiC5aYToJGlEPTBib3[gNE44PiEQvF2= NHrHTlEyPzR5N{WxPC=>
RAW264.7 NHjGUmZHfW6ldHnvckBCe3OjeR?= NEDnS3YyOCEQvF2= NEi0VnAzPGh? NH7FPFh4[XSnch?= MnjJTY5pcWKrdHnvckBw\iCOUGOtd5RqdXWuYYTl[EBPVyCycn;keYN1cW:wIIfpeIghUUN3MDDv[kAyNjh6IN88US=> M{C3W|E4PDd5NUG4
SC9 NIe3ZnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mmq0OFghcA>? MkHhTWM2OD1yLk[wOkDPxE1? NH;KN2QyPzVyN{KxPS=>
ST14A NFy5VGVHfW6ldHnvckBCe3OjeR?= NWjnTpN2PSCwTR?= MlL1O|IhcA>? NIXafYlKdmO{ZXHz[UBqdiCURWPUM25TW0ZibWLORUBmgHC{ZYPzbY9v MkPoNVc2PjV7OUO=
ST14A M4jWZ2Z2dmO2aX;uJGF{e2G7 NIH2enM2KG6P M4m1SFczKGh? M{DsU2lv[3KnYYPlJIlvKEV{RkGgcXJPSSCneIDy[ZN{cW:w MmH3NVc2PjV7OUO=
PANC1 NW\JT|F{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF:2c4QyKM7:TR?= MkHlTWM2OD1yLkS1JO69VQ>? M1\YRlE4PTh6N{S0
PANC1 NIK0e29HfW6ldHnvckBCe3OjeR?= M1OxflEh|ryP MXuyOEBp MWXJcoNz\WG|ZTDpckBxOjGZQV[xM2NKWDFiZ3Xu[UBmgHC{ZYPzbY9v NYmyRY1uOTd3OEi3OFQ>
PANC1 NEHaZYVHfW6ldHnvckBCe3OjeR?= NFr3PFAyKM7:TR?= MVeyOEBp NYHl[|ZMUW6lcnXhd4UhcW5icEK3b4lxOSCpZX7lJIV5eHKnc4Ppc44> NXTLT|hXOTd3OEi3OFQ>
PT45 NXi2d|hHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHh[XZ2UUN3ME20JO69VQ>? Moe1NVc2QDh5NES=
ACHN M3TlZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUPJV|ZvOjFiaB?= MV7HTVUxRTBwNkWg{txO MYSxO|Y3OjZyNh?=
PC3 NI\0dpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M33Gb|IyKGh? MnrLS2k2OD1yLkexJO69VQ>? M2Pyc|E4PjZ{NkC2
A431 NFrGNmdEgXSxdH;4bYMhSXO|YYm= Ml\XO|IhcA>? MXfJR|UxRTRwMjFOwG0> MnjwNVc3QTF5NkO=
Cal27 NU\iV2xwS3m2b4TvfIlkKEG|c3H5 M4LjU|czKGh? MonyTWM2OD1|LkKg{txO NWrRNlBJOTd4OUG3OlM>
CCRF-CEM NX;tZYlLS3m2b4TvfIlkKEG|c3H5 Mn\3O|IhcA>? NUHlRXR3UUN3ME2wMlgh|ryP MmPuNVc3QTF5NkO=
EOL1 NGjadG9EgXSxdH;4bYMhSXO|YYm= NF7DNJc4OiCq NX3aZpM5UUN3ME2xJO69VQ>? MofFNVc3QTF5NkO=
Hec-1-A M3TYZWN6fG:2b4jpZ{BCe3OjeR?= NFLU[ZY4OiCq MmrjTWM2OD1zIN88US=> MkLDNVc3QTF5NkO=
HeLa MWLLbY5ie2ViQYPzZZk> MW[xNEDPxE1? MYGzNEBucW5? MWfEUXNQ NXrzeG5pUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBJTEGFMTD3bZRpKEmFNUCgc4YhOC5yMjFOwG0> M4DwRlE4PjlzN{[z
RKOp21 MlW3R5l1d3SxeHnjJGF{e2G7 MVu3NkBp MlfMTWM2OD1zLke2JO69VQ>? NFPtNYoyPzZ7MUe2Ny=>
Saos2 MUfDfZRwfG:6aXOgRZN{[Xl? M1OzPFczKGh? MWLJR|UxRTJwMzFOwG0> MlvGNVc3QTF5NkO=
SK-OV-3 NVfYZXVvS3m2b4TvfIlkKEG|c3H5 NETzc|Y4OiCq M1y0XmlEPTB;Mj6yJO69VQ>? MXqxO|Y6OTd4Mx?=
U87MG NUC3Rph4S3m2b4TvfIlkKEG|c3H5 Mmq0O|IhcA>? MVjJR|UxRTFzIN88US=> MWGxO|Y6OTd4Mx?=
NUGC3 MlvlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2DWXVUh|ryP MXiyOEBp MUHHTVUxRTJwN{mg{txO M4Hle|E4QTB2OESz
CCD1059SK MmDqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;xbIVKSzVyPUSzMlUh|ryP NHLBcXcyQDJ2N{W1OC=>
HepG2 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHroS|JKSzVyPUCuNFAxPiEQvF2= M{nUS|E5OjR5NUW0
HT1080 Ml;YS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlHPTWM2OD1yLkCwNlQh|ryP M37DdVE5OjR5NUW0
SKBR3 NEfUUIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWfjPG9MUUN3ME2wMlgh|ryP NG[2UYkyQDJ2N{W1OC=>
SNB78 M{fzfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHH6UlJGSzVyPUG2JO69VQ>? NHvyPXgyQDJ2N{W1OC=>
SQ20B M3niW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnIUIxIUUN3ME2zJO69VQ>? NGPQ[mwyQDJ2N{W1OC=>
St4 NWHVTmNPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1HNOGVEPTB;NT6yJO69VQ>? NWO5d2N4OTh{NEe1OVQ>
MCF7 NVXZRoFNTnWwY4Tpc44hSXO|YYm= M3HRWVExKM7:TR?= Ml;QPEBp M4jZS2ROW09? NF3zVJFKdmS3Y4Tpc44hd2ZidIXieYxqdiCqeYDldoFk\XS7bHH0bY9v MXyxPFI3QTJ{Nh?=
HEK293 MnTjT4lv[XOnIFHzd4F6 Mm\TNUBp M33nTWROW09? NFzrUXZKdmirYnn0bY9vKG:oIFjERWMyKHerdHigTWM2OCCxZjCwMlA{KM7:TR?= MlfkNVg{ODh3NkO=
HEK293 NFnkcXdMcW6jc3WgRZN{[Xl? M2nyUVEhcA>? M1jHSGROW09? NEjYTVBKdmirYnn0bY9vKG:oIFjERWM{KHerdHigTWM2OCCxZjCwMlA2PyEQvF2= NXzEc4NtOTh|MEi1OlM>
G401 MknlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWm3NkBp NUjEV49qTE2VTx?= NWKzR2ZqUUN3ME2xJO69VQ>? NHLJe3cyQDN5MEO3Ny=>
HeLa MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXH4SVBHPzJiaB?= MYfEUXNQ NYnmfpZNUUN3ME2wMlQ3KM7:TR?= M1m1OlE5OzdyM{ez
Human renal epithelial cell M4r6Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmnPO|IhcA>? MVfEUXNQ NWDyTZhtUUN3ME2xOEDPxE1? NVru[Xl{OTh|N{CzO|M>
U937 MWrGeY5kfGmxbjDBd5NigQ>? MV[1JO69VQ>? MXSyOEBp M{DHTmlv\HWldHnvckBw\iCqaYP0c45mKEh2IHj5dIVz[WOndInsZZRqd25? MY[xPFM5OTJ|OB?=
U937 MW\GeY5kfGmxbjDBd5NigQ>? MXS1JO69VQ>? M13ubVI1KGh? M4fKdWlv\HWldHnvckBw\iCjbIDoZUB1fWK3bHnuJIh6eGW{YXPleJlt[XSrb36= Mo[3NVg{QDF{M{i=
U937 NWnnVFI2TnWwY4Tpc44hSXO|YYm= M2K3bFUh|ryP MlLNNlQhcA>? MlrBTY5lfWO2aX;uJI9nKHB{MTDlfJBz\XO|aX;u NIHCfIsyQDN6MUKzPC=>
U937 M2jUeWZ2dmO2aX;uJGF{e2G7 MnLFOUDPxE1? M2HjdVI1KGh? MX7JcoR2[3Srb36gc4Yh[XCxcITvd4l{ NEHyfpUyQDN6MUKzPC=>
U937 NEi2b2xHfW6ldHnvckBCe3OjeR?= Mn3COUDPxE1? MkPVNlQhcA>? NGnweXNKdmS3Y4Tpc44hd2ZiZ4LhcpVtd2O7dHnjJIRq\m[ncnXueIlifGmxbh?= NXKwTldYOTh|OEGyN|g>
U937 M1f1eWtqdmG|ZTDBd5NigQ>? MU[1JO69VQ>? NE\HOVYzPCCq NHPK[WtKdmirYnn0bY9vKG:oIHj1cYFvKEiGQVOx NUDlPHNTOTh|OEGyN|g>
U937 M4Thc2tqdmG|ZTDBd5NigQ>? MlTWOUDPxE1? NXn6VI5DOjRiaB?= NHTNTIdKdmirYnn0bY9vKG:oIHj1cYFvKEiGQVO0 NUC0WlFxOTh|OEGyN|g>
HEK-TE NYn6[Ik4TnWwY4Tpc44hSXO|YYm= M1\EU|Uh|ryP MnfQOog> NXPjT5NrTE2VTx?= NHvhbWVKdmO{ZXHz[UBqdiCqaYP0c45mKEh|IHHj[ZR6dGG2aX;u MnnVNVg1OzRzNES=
HPDE6c7 MVPDfZRwfG:6aXOgRZN{[Xl? MUK1NEDPxE1? MVm3NkBp NXLFbpdjTE2VTx?= MXnJR|UxRTFwMzFOwG0> NXjNU2NnOTh2OUS0OlM>
Human microvascular epithelial cell MkXyR5l1d3SxeHnjJGF{e2G7 NYTpT2VEPTBizszN NVHIUItJPzJiaB?= NWrnR2VqTE2VTx?= M1HhdmlEPTB;MT6zJO69VQ>? NVXHPIczOTh2OUS0OlM>
Hup T3 M1i3d2N6fG:2b4jpZ{BCe3OjeR?= MnexOVAh|ryP NY\NUWpVPzKq MVrEUXNQ MXPJR|UxRTBwODFOwG0> NXzzWXJmOTh2OUS0OlM>
Mia Paca2 MYjDfZRwfG:6aXOgRZN{[Xl? NWD6TVBnPTBizszN M3zUcVczcA>? MXzEUXNQ NFvOTm9KSzVyPUGuNUDPxE1? MWmxPFQ6PDR4Mx?=
Panc 04.03 M{fiXWN6fG:2b4jpZ{BCe3OjeR?= NV\hOlFOPTBizszN MVi3Nog> MUHEUXNQ MV;JR|UxRTFwMjFOwG0> NFrpRnMyQDR7NES2Ny=>
SU 86.86 NHz5NHJEgXSxdH;4bYMhSXO|YYm= M{nxZ|UxKM7:TR?= NI\EWJo4Omh? MoTVSG1UVw>? Mny1TWM2OD1zLkOg{txO MmWwNVg1QTR2NkO=
HEK293 M4HXNGtqdmG|ZTDBd5NigQ>? NYHNZlFFOyCq MV\Jcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IFjERWM3KGW6cILld5Nqd25id3n0bEBKSzVyIH;mJFAvODF7IN88US=> MmO0NVg2PTh4Nkm=
HeLa NYfTZWE2U2mwYYPlJGF{e2G7 NFjxdlAzKGh? MnHMTY5pcWKrdHnvckBw\iCwdXPs[YFzKEiGQVOge4l1cCCLQ{WwJI9nKDBwMEizJO69VQ>? M3TwclE5PTV6Nk[5
RAW264.7 M{joUGZ2dmO2aX;uJGF{e2G7 MoHiNkDPxE1? MonQN{42KGh? MmDoSG1UVw>? M1jGfGFvfGmvYXzhdolidCCjY4Tpeol1gSCjZ3HpcpN1KFCuYYPtc4RqfW1iZnHsZ4lx[XK3bTDpcoZm[3SnZDD3bZRpKEmFNUCgc4YhOC5zMTFOwG0> MmrMNVg3PDR7Nkm=
NB4 MUm0PIg> NFLoOmNFVVOR M2nlZ2lEPTB;MD62JO69VQ>? MVqxPFczOzN2OR?=
HEK293 M2f6VmZ2dmO2aX;uJGF{e2G7 NFO4OG4yOCEQvF2= NGHR[YczPCCq NYHJN2VNTE2VTx?= MkGwRYN1cX[jdHnvckBw\iCvb4Xz[UBYdnR|YTDzbYdv[Wyrbneg[ZhxemW|c3Xk NWfBbndOOTlyMkK2O|U>
HCT116 NYe5[md{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlvxO|Jp MWrEUXNQ NEjGcnVKSzVyPUCuN|Eh|ryP NEnmcWEyQTB6NEK5OC=>
HeLa MV\LbY5ie2ViQYPzZZk> NWHyb5gyOiEQvF2= M2fJ[VMxKG2rbh?= NGewWlhFVVOR M4PwPGlvcGmkaYTpc44hd2ZiSFTBR|IhcW5iaIXtZY4hUGWOYTDj[YxteyC5aYToJGlEPTBib3[gNE4yKM7:TR?= MV2xPVA5PDJ7NB?=
IGROV1 MmTqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\HZ5FOPzJiaB?= M1;LdWROW09? NFTsWmVKSzVyPUKuNkDPxE1? M4naWlE6ODh2Mkm0
IGROV1 M2jqWWtqdmG|ZTDBd5NigQ>? MYW1JO69VQ>? NETENYUzPCCq MX;EUXNQ NEHGU4FKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNicEWzJIFk\XS7bHH0bY9v M4TNOVE6ODh2Mkm0
IGROV1 NXW1OpFGU2mwYYPlJGF{e2G7 MV2xNEDPxE1? NHjFUoo1KGh? MnHoSG1UVw>? NFPlVVJKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaHnzeI9v\S2KNDDhZ4V1gWyjdHnvci=> MmrNNVkxQDR{OUS=
IGROV1 M1\rfmtqdmG|ZTDBd5NigQ>? MmPoNVAh|ryP NVG5[pd7PCCq NI\vXmtFVVOR NUH1UpJrUW6qaXLpeIlwdiCxZjDISGFEPiCjc4Pld5Nm\CCjczDhcJBp[S22dXL1cIlvKGGlZYT5cIF1cW:w M4WycFE6ODh2Mkm0
T24 M4XMO2tqdmG|ZTDBd5NigQ>? MYmzJIg> NXLIR4pwUW6mdXP0bY9vKG:oIHjpd5RwdmViSEOgZYNmfHmuYYTpc44hf2m2aDDFR|UxKG:oIECuNVIh|ryP NFv4WpMyQTB6NEO5OS=>
T24 NYHxU4FjU2mwYYPlJGF{e2G7 NHPMTWY{KGh? MlvZTY5lfWO2aX;uJI9nKGGucHjhJJR2[nWuaX6gZYNmfHmuYYTpc44hf2m2aDDFR|UxKG:oIECuNlUh|ryP MUOxPVA5PDN7NR?=
HeLa NV[3NGJNU2mwYYPlJGF{e2G7 MYGxOUBucW5? NI[5c2xFVVOR NYr0OFdDUW6qaXLpeIlwdiCxZjDISGFEPiCocn;tJI52[2ynYYKg[Zh1emGldDD3bZRpKEmFNUCgc4YhOC5yOEW1JO69VQ>? M1fVSFE6ODl|OEi0
HeLa NH31dnhMcW6jc3WgRZN{[Xl? M3XlR|E2KG2rbh?= NIe1d49FVVOR M3S3W2lvcGmkaYTpc44hd2ZiSFTBR|gh\nKxbTDueYNt\WG{IHX4eJJi[3Rid3n0bEBKSzVyIH;mJFEvQDZizszN Ml[xNVkxQTN6OES=
NCI-H69 M{OxTWN6fG:2b4jpZ{BCe3OjeR?= MVe3NkBp M2\SemROW09? MV\JR|UxRTJwME[g{txO NHrIR2gyQTB7M{i4OC=>
SKMES1 NGP3TnpEgXSxdH;4bYMhSXO|YYm= MmXuO|IhcA>? Mn:zSG1UVw>? NXfjO2p2UUN3ME2yMlQzKM7:TR?= M{jkO|E6ODl|OEi0
S2 MXLLbY5ie2ViQYPzZZk> M1fpWlAvOS1zMDFOwG0> MmP2NUBp MV\Jcohq[mm2aX;uJI9nKFCuYYPtc4RqfW1iZnHsZ4lx[XK3bTDISGFEOSCneIDy[ZN{\WRid3n0bEBKSzVyIH;mJFAvODV7IN88US=> MmXsNVk{OTd2NUC=
SHSY5Y MXLLbY5ie2ViQYPzZZk> MVKxNEDPxE1? NWTKVFBNPDhiaB?= MX7EUXNQ M4[3RWlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD61JO69VQ>? MYexPVM1PDF5NR?=
SHSY5Y M4TwZmN6fG:2b4jpZ{BCe3OjeR?= M37IS|ExKM7:TR?= NXSwdFVnPDhiaB?= Mo[2SG1UVw>? MkOwTWM2OD1{IN88US=> Mn7GNVk{PDRzN{W=
DMS114 NGjvfFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF\aS5A1QCCq NFPJ[VNIUTVyPUKuPUDPxE1? NFzOSpMyQTRzOUKwOS=>
HBC5 NVrIV4tTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofEOFghcA>? M{TwfWdKPTB;MUeg{txO MofwNVk1OTl{MEW=
SNB78 NE\ufXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mnu3OFghcA>? NF:3cI1IUTVyPUG2JO69VQ>? NIjUb4EyQTRzOUKwOS=>
HeLa NV3tOHFwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXLUNo81PzJiaB?= M{KxS2ROW09? NUPxVZgyUUN3ME2wMlQ3KM7:TR?= MnrFNVk1PDF6NE[=
BHK NGjWcXpMcW6jc3WgRZN{[Xl? MonBOUDPxE1? NV\kfpRsOjRiaB?= M3i4O2ROW09? NFzEfmtKdmirYnn0bY9vKG:oIFjERWM4KGW6cILld5Nm\CCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBxdGG|bXGgcYVu[nKjbnWgSoRmdHSjNUC4JGNHXFJicILveIVqdg>? M2XoRlE6QTZ4N{i5
CFBE41o- NYHyNW5xU2mwYYPlJGF{e2G7 NF32PHo2KM7:TR?= MmjCPEBp NEnTNmZFVVOR NH\xSldKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaInw[ZJi[2W2eXzheIlwdiCxZjDobZN1d26nIFiz NYewNnF2OTl7Nk[3PFk>
CFBE41o- Mmf5T4lv[XOnIFHzd4F6 MUS1JO69VQ>? M4G4OFQhcA>? NFzrb5FFVVOR M{XYfGlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDteZRidnRiRnTlcJRiPTB6IFPGWHIheHKxdHXpckBt\X[nbB?= M17XWlE6QTZ4N{i5
CFBE41o- M1fsSmtqdmG|ZTDBd5NigQ>? MUGxJO69VQ>? NECwUI0yKGh? MkKxSG1UVw>? NFy2PJVKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gR2ZVWiCycn;0[YlvKGyndnXs Mn:1NVk6PjZ5OEm=
Primary bronchial epithelial cell NYnXPZg4U2mwYYPlJGF{e2G7 MYSxJO69VQ>? Mk\6NlQhcA>? MYfEUXNQ M2ewNGlvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJI12fGGwdDDG[IVtfGF3MEigR2ZVWiCycn;0[YlvKGGyaXPhcEB{fXKoYXPlJIxw[2GuaYrheIlwdg>? NFT6XXgyQTl4Nke4PS=>
CFBE41o- MXLLbY5ie2ViQYPzZZk> NHX2bIEyKM7:TR?= MonxOUBl[Xm| NGS5PGVFVVOR NHjaR3VKdmirYnn0bY9vKG:oIFjERWM4KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJJN1[WKrbHn6ZZRqd25ib3[gSoRmdHSjNUC4JGNHXFJicILveIVqdg>? NU\HOlJGOTl7Nk[3PFk>
CFBE41o- Mny3T4lv[XOnIFHzd4F6 MnHoNUDPxE1? MlLGNlQhcA>? M3;BSGROW09? Moi5TY5pcWKrdHnvckBw\iCKRFHDO{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDG[IVtfGF3MEigR2ZVWiCycn;0[YlvKHS{YX\mbYNscW6p NVLOXmpvOTl7Nk[3PFk>
CFBE41o- NEjBSoFMcW6jc3WgRZN{[Xl? MmK1OUDPxE1? M4n5dlI1KGh? NXPidYltTE2VTx?= M1LzXGlvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gdoF1\SCxZjDtZZR2emG2aX;uJI9nKEOIVGKgdJJwfGWrbjD0c{BqfHNiZ3z5Z49nd3Kv M1\RVFE6QTZ4N{i5
CFBE41o- NFnXdWhMcW6jc3WgRZN{[Xl? NV\DTVlpPSEQvF2= MVuyOEBp NGC0TYVFVVOR Mn;lTY5pcWKrdHnvckBw\iCKRFHDO{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDzeIFjcWyrdImgc4YhTmSnbIThOVA5KEOIVGKgdJJwfGWrbh?= MlzGNVk6PjZ5OEm=
CFBE41o- M2q5[2tqdmG|ZTDBd5NigQ>? MY[1JO69VQ>? MnXsNlQhcA>? NGfYS5lFVVOR MkHQTY5pcWKrdHnvckBw\iCKRFHDO{Bie3Onc4Pl[EBieyClb4Ly[YN1cW:wIH;mJI12fGGwdDDG[IVtfGF3MEigR2ZVWiC2cnHm[olkc2mwZzD0c{Bk\WyuIIP1doZi[2ViYYOg[4x6[2:ob4Lt MmfWNVk6PjZ5OEm=
Primary bronchial epithelial cell NYLtOlZjU2mwYYPlJGF{e2G7 NUPqRYpXPSEQvF2= MWOyOEBp NETOR2pFVVOR NFvscmZKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJI12fGGwdDDG[IVtfGF3MEigR2ZVWiCycn;0[YlvKGGyaXPhcEB{fXKoYXPlJIxw[2GuaYrheIlwdg>? Mn2wNVk6PjZ5OEm=
Primary bronchial epithelial cell M1zFUWtqdmG|ZTDBd5NigQ>? NGHMVIIyKM7:TR?= NGDxV|I6PiCq M4PISmROW09? NEHBV2lKdmirYnn0bY9vKG:oIFjERWM4KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJJNpd3K2IHPpdoN2cXRiY4XydoVvfHN? M2ezNlE6QTZ4N{i5
BxPC3 NIf2RmdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUS3NkBp Mk\QTWM2OD1{Lkeg{txO MliwNlAyPDN5N{i=
CAL27 NXu2WGliT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mny3O|IhcA>? MmnsTWM2OD1|LkeyJO69VQ>? MY[yNFE1Ozd5OB?=
Capan1 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4frPFczKGh? M{P2WWlEPTB;Nz6zJO69VQ>? NUf6WJpFOjBzNEO3O|g>
HCC827 NH;tV21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF3mOYY4OiCq MkPTTWM2OD1zLkig{txO NFjvR3gzODF2M{e3PC=>
LNCAP M4nvUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGO4R3U4OiCq Mn;hTWM2OD1yLkW4JO69VQ>? NXLvc4tqOjBzNEO3O|g>
NCI-H2122 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY[3NkBp NV;wWJFXUUN3ME23MlUh|ryP MnH5NlAyPDN5N{i=
NCI-H358 MlvYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnLkO|IhcA>? NHvkSVFKSzVyPUKuOUDPxE1? NGTaeGgzODF2M{e3PC=>
SCC15 NFK2UVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmC4O|IhcA>? MV7JR|UxRTJwNEmg{txO Mkj3NlAyPDN5N{i=
SCC25 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mo\tO|IhcA>? MnTnTWM2OD1zLkmzJO69VQ>? Ml7sNlAyPDN5N{i=
SKHEP1 Ml;mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVu3NkBp NGP4[nZKSzVyPUOuOFYh|ryP NFTISFMzODF2M{e3PC=>
BJ NXqxS2Q2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\FXFExOCEQvF2= M3:xclQ5KGh? NHi1dmdFVVOR MkjjS5Jwf3SqIHnubIljcXSrb36gZZQhOC5yNTD0c{AyODBidV2= NYDiWHR1OjBzNEO4OFA>
MUF MmK2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M37wT|ExOCEQvF2= NHzRUo81QCCq MUnEUXNQ MW\Hdo94fGhiaX7obYJqfGmxbjDheEAxNjB3IITvJFExOCC3TR?= M4TLRlIxOTR|OESw
Caco-2 MojVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3K5TVExOCEQvF2= NWHUfWRLPDiq MnfPSG1UVw>? NFzYSoxKSzVyPUiuNUDPxE1? MVWyNFE1Ozh2MB?=
Caco-2 M4\4[WtqdmG|ZTDBd5NigQ>? MlriOUDPxE1? MoHOOEBp MW\EUXNQ MXvJcoR2[3Srb36gc4YhUESDQz3t[YRq[XSnZDDobZN1d26nIHHj[ZR6dGG2aX;uJGlEPTBib3[gNE4xOzdizszN M4rwOlIxOTR|OESw
Caco-2 NVjDWHhoU2mwYYPlJGF{e2G7 MmHENE4{OTZibl2geI8hOzFwNjFOwG0> MnP0OEBp NYKxb4Y4TE2VTx?= NFjacm9GgCC4aY\vJIlvcGmkaYTpc44hd2ZiaIXtZY4hUESDQ{Gge4l1cCCLQ{WwJI9nKDBwMUG5JO69VQ>? NV3JNJJxOjBzNEO4OFA>
Caco-2 NXrw[3NQU2mwYYPlJGF{e2G7 NHrWWG0xNjNzNjDuUUB1dyB|MT62JO69VQ>? M1fIVVQhcA>? Ml;SSG1UVw>? M33QS2V5KH[rdn:gbY5pcWKrdHnvckBw\iCqdX3hckBJTEGFMzD3bZRpKEmFNUCgc4YhOC5zNEeg{txO NFjCUogzODF2M{i0NC=>
Caco-2 MWnLbY5ie2ViQYPzZZk> MVq2MlMzKG6PIITvJFY{OiEQvF2= MV20JIg> NF23eVFFVVOR M1XMc2V5KH[rdn:gbY5pcWKrdHnvckBw\iCqdX3hckBJTEGFNTD3bZRpKEmFNUCgc4YhOTJwNjFOwG0> M33BSlIxOTR|OESw
Caco-2 M{TMV2tqdmG|ZTDBd5NigQ>? MW[2MlMzKG6PIITvJFY{OiEQvF2= NYLMeIsxPCCq MWPEUXNQ NXvJPVluTXhidnn2c{BqdmirYnn0bY9vKG:oIHj1cYFvKEiGQVO3JJdqfGhiSVO1NEBw\iB2MTFOwG0> Mn[5NlAyPDN6NEC=
Caco-2 M{fOUGtqdmG|ZTDBd5NigQ>? M{\l[lAvOzF4IH7NJJRwKDNzLk[g{txO MmjuOEBp NVG2XVV6TE2VTx?= NFzaUm9GgCC4aY\vJIlvcGmkaYTpc44hd2ZiaIXtZY4hUESDQ{[= MVuyNFE1Ozh2MB?=
HepG2 M3rT[GtqdmG|ZTDBd5NigQ>? MYW1JO69VQ>? NYHXXY45Pmh? NG\ET2JFVVOR NUmwbZVZUW6mdXP0bY9vKG:oIFjERWMudWWmaXH0[YQhcGm|dH;u[UBi[2W2eXzheIlwdg>? MXyyNFE1Ozh2MB?=
HepG2 NFPTNWhMcW6jc3WgRZN{[Xl? MmDSOUDPxE1? MXi2bC=> M2XiSWROW09? NHfPWGFKdmS3Y4Tpc44hd2ZiSFTBR{1u\WSrYYTl[EBpcXO2b37lJIh6eGW{YXPleJlt[XSrb36= Mn3pNlAyPDN6NEC=
HepG2 Mn:wT4lv[XOnIFHzd4F6 M4W4RlUh|ryP NHW1Omg3cA>? M1:zNmROW09? NYezO5B{UW6mdXP0bY9vKG:oIFjERWMudWWmaXH0[YQh[WyyaHGteJVjfWyrbjDhZ4V1gWyjdHnvci=> M3PiUVIxOTR|OESw
HepG2 M4\uU2tqdmG|ZTDBd5NigQ>? NUC0N|VMPSEQvF2= NHTYT4I3cA>? MWfEUXNQ MWLJcoR2[3Srb36gc4YhUESDQz3t[YRq[XSnZDDIN{9JPCCqaYP0c45mKGGlZYT5cIF1cW:w MWiyNFE1Ozh2MB?=
COLO205 MVfLbY5ie2ViQYPzZZk> NULzUIRyOTBizszN NXT3c5VQOjRiaB?= M2HzeGROW09? NFHKfHBKdmirYnn0bY9vKG:oIFjERWMyKGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBpcXO2b37lJGg{KGGlZYT5cIF1cW:wIIfpeIghUUN3MDDv[kAzNjJizszN Mk\hNlA1PTF|N{i=
SCC4 NUTnV4Z4U2mwYYPlJGF{e2G7 MkPqNUDPxE1? M1zrOVI1cA>? MUPJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5idIXieYxqdiCjY3X0fYxifGmxbh?= NFHuUJMzODR3MkKyOS=>
SCC4 M{DJd2tqdmG|ZTDBd5NigQ>? MmH2NUDPxE1? NUC2fmN2OjSq M{PCVWlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIHHj[ZR6dGG2aX;u M1LR[VIxPDV{MkK1
SCC4 M4TR[2Z2dmO2aX;uJGF{e2G7 MV6xJO69VQ>? NHrmSXQ2KG2rbh?= MlrnRYdwdmm|dDDhZ5Rqfmm2eTDheEBXTFJiYYPz[ZN{\WRiYYOgbY5lfWO2aX;uJI9nKEO\UEK0JIdmdmViZYjwdoV{e2mxbh?= NILhfm8zODR3MkKyOS=>
NB4 NH:1ZZlHfW6ldHnvckBCe3OjeR?= M{PoTVUh|ryP MlfCNlQhcA>? Mne2SG1UVw>? NVfxSHZ1S2WubDDjfYNt\SCjcoLld5Qh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gZYNkfW23bHH0bY9vKGG2IIDy[U1IOSCyaHHz[S=> M2DPXlIxPDlzNESw
NB4 NELzZ5NMcW6jc3WgRZN{[Xl? MkXUOUDPxE1? MWeyOEBp NELiWlBFVVOR MU\Jcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iYXPleJlt[XSnIIT1ZpVtcW5ibHX2[Yw> NXPXSFhnOjB2OUG0OFA>
NB4 NWrafJg6TnWwY4Tpc44hSXO|YYm= NH7uUo82KM7:TR?= MV2yOEBp MWHEUXNQ NYT0cmN6UW6mdXP0bY9vKG:oIICyNXdCTjFxQ1nQNUBmgHC{ZYPzbY9v NECzcmMzODR7MUS0NC=>
NB4 M4[0ZWtqdmG|ZTDBd5NigQ>? Mkn2OUDPxE1? MVeyOEBp NFO3O4hFVVOR MYPJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDhZ4V1gWyjdHnvci=> M1\uZlIxPDlzNESw
NUGC3 NYXUS|JoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHL0U4hIUTVyPUKuPVQh|ryP MkHKNlA5PTB7N{G=
A549 NF3uUYlHfW6ldHnvckBCe3OjeR?= NVXMR4M5PSEQvF2= MUmzJIg> MmjXSG1UVw>? MXPJcoR2[3Srb36gc4Yh[XW2b4DoZYd6KGmwIHj1cYFvKEF3NEmgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hVEN|SVm= Mmf6NlA5PTV{MEi=
HUT78 NHH0TVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\0Ump3PzJiaB?= M1TydWROW09? M2ixPWdKPTB;MD6zJO69VQ>? NXLUU4FUOjB6OESyNFg>
U937 NFfVfYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTPVXU6PzJiaB?= M1\DSWROW09? MojhS2k2OD1yLkO5JO69VQ>? NUnCe2dPOjB6OESyNFg>
A431 MVfDfZRwfG:6aXOgRZN{[Xl? NXLHbWVwPzJiaB?= MoO4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVQ{OSClZXzsd{BwfmW{ZYjwdoV{e2mwZzDFS2ZTKHerdHigTWM2OCCxZjC0MlIh|ryP NFeyZXEzOTB6ME[yPS=>
A549 M3fFVGN6fG:2b4jpZ{BCe3OjeR?= MlvLO|IhcA>? NF75cGtEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KG:4ZYLlfJBz\XO|aX7nJGhFSUNid3n0bEBKSzVyIH;mJFEvQCEQvF2= MWWyNVA5ODZ{OR?=
CAL27 M4TpfmN6fG:2b4jpZ{BCe3OjeR?= Mk\CO|IhcA>? NX;pPW1wS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hS0GOMkegZ4VtdHNib4\ldoV5eHKnc4PpcochTUeIUjD3bZRpKEmFNUCgc4YhOy5{IN88US=> MVSyNVA5ODZ{OR?=
HeLa NV7ZdINwS3m2b4TvfIlkKEG|c3H5 MWG3NkBp MVXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJI93\XKneIDy[ZN{cW6pIFjERWMhf2m2aDDJR|UxKG:oIEGuOUDPxE1? NEjiN2YzOTB6ME[yPS=>
Sf21 NIP3eo5McW6jc3WgRZN{[Xl? MnrHN{Bp NVXMOppGUW6qaXLpeIlwdiCxZjDGcIFoKHSjZ3fl[EBpfW2jbjDy[YNwdWKrbnHueEBJTEGFODDlfJBz\XO|ZXSge4l1cCCLQ{WwJI9nKDFwMjFOwG0> MoDDNlExQDB4Mkm=
SKBR3 M1Lmd2N6fG:2b4jpZ{BCe3OjeR?= NWXhSnJjPzJiaB?= MnHLR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2tDWjNiY3XscJMhd3[ncnX4dJJme3OrbnegTGVTOiC5aYToJGlEPTBib3[gNk43KM7:TR?= M1P5NVIyODhyNkK5
SKOV3 MUHDfZRwfG:6aXOgRZN{[Xl? Mn:xO|IhcA>? NHzwS4NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUU0:YMzDj[YxteyCxdnXy[ZhxemW|c3nu[{BJTVJ{IIfpeIghUUN3MDDv[kAzNjJizszN NH3TcI8zOTB6ME[yPS=>
COR-L23 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnHtNVAh|ryP M4rqbVczKGh? NHXIcIpFVVOR M1;ucmdKPTB;MT6xJO69VQ>? NFG1cGwzOTB6ME[0Oy=>
DU145 NIjQU2dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVSxNEDPxE1? NYTBbGFFPzJiaB?= NIiye4xFVVOR M{mxdmdKPTB;MT6wOUDPxE1? MoLNNlExQDB4NEe=
LoVo NXXMVYZvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVHlWnBMOTBizszN M4Pj[lczKGh? NYrl[WNmTE2VTx?= M2nCO2dKPTB;MT63JO69VQ>? MnfhNlExQDB4NEe=
MCR5-SV2 NXz4SpRHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1XVfVExKM7:TR?= M1;PdFczKGh? NFPwbW9FVVOR NID0NoVIUTVyPUKuNUDPxE1? NFz4UogzOTB6ME[0Oy=>
HCT116 M{HDR2tqdmG|ZTDBd5NigQ>? NWfybXQyOzBizszN MmqxN|AhcA>? MnnoSG1UVw>? NITGSIVKdmirYnn0bY9vKG:oIFjERWM3KGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBidHCqYT30eYJ2dGmwIHHj[ZR6dGG2aX;u MX6yNVA5ODZ2Nx?=
HCT116 MYnLbY5ie2ViQYPzZZk> MVuzNEDPxE1? MXGzNEBp MljUSG1UVw>? M3H0[GlvcGmkaYTpc44hd2ZiSFTBR|Eh[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJIhqe3SxbnWgTFNMQSCjY3X0fYxifGmxbh?= NIHGUnYzOTB6ME[0Oy=>
U937 M2rrRmtqdmG|ZTDBd5NigQ>? MWO1JO69VQ>? NHSyUlQzPCCq NWj6WnJHTE2VTx?= M2fDfWlvcGmkaYTpc44hd2ZiaHnzeI9v\SCjY3X0fYx1emGwc3\ldoF{\SCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDv[kBi[2W2eXzheIlwdiCxZjDobZN1d26nIFizJIF1KEt7 M13jTFIyOjl{NEmy
U937 MXjLbY5ie2ViQYPzZZk> M3y3WVUh|ryP NWjpc4VrOjRiaB?= MX7EUXNQ MUXJcohq[mm2aX;uJI9nKGirc4TvcoUh[WOndInseJJidnOoZYLhd4Uh[XO|ZYPz[YQh[XNiaX7jdoVie2Vib3[gZYNmfHmuYYTpc44hd2ZiaHnzeI9v\SCKMzDheEBMOTh? NY\6d4pPOjF{OUK0PVI>
U937 Ml3kT4lv[XOnIFHzd4F6 M3LZRlUh|ryP M3e0[VI1KGh? M13Vb2ROW09? NYLqd4V{UW6qaXLpeIlwdiCxZjDobZN1d26nIHHj[ZR6dHS{YX7z[oVz[XOnIHHzd4V{e2WmIHHzJIlv[3KnYYPlJI9nKHCjbj3hZ4V1gWyjdHXkJIhqe3SxbnWgTFQhdGW4ZXy= NHfOUWozOTJ7MkS5Ni=>
U937 MWLLbY5ie2ViQYPzZZk> M{XFXVUh|ryP NVfkToFCOTVibXnu NIO1[I9FVVOR MlG5TY5pcWKrdHnvckBw\iCqaYP0c45mKGGlZYT5cJRz[W6|ZnXyZZNmKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIH;mJIhqe3SxbnWgTFMh[WOndInsZZRqd25ibHX2[Yw> MViyNVI6OjR7Mh?=
A2780 MlnBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NETHXFY6PiCq NFv0RplFVVOR MlPOTWM2OD1zLk[yJO69VQ>? M1voRVIyPjN2NEOw
COLO205 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXjESlg{QTZiaB?= NYHORWFDTE2VTx?= M{jkd2lEPTB;Mj6xNkDPxE1? NXvneG1yOjF4M{S0N|A>
Hep3B MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnhSW81QCCq MV;EUXNQ MoiyS2k2OD1zLkKxJO69VQ>? Mof4NlE4OTJzNE[=
GM11272 NUTW[WJVTnWwY4Tpc44hSXO|YYm= NGC3e28yODBibl2= MXi3NkBp M3rrcWROW09? Mor3VoVi[3SrdnH0bY9vKG:oIF3lR5AzKG23dHHueEBmgHC{ZYPzbY9vKGG2IEGwJJRwKDFyMDDuUS=> M4LRW|IyQDRyN{G2
CFBE41o MmXPT4lv[XOnIFHzd4F6 MmO0OUDPxE1? NIrVOlFFVVOR NHPhbmhFd3ewIILl[5Vt[XSrb36gc4YhUESDQ{egZZQhOC5{IITvJFUhfU1? NYn0[|ZZOjF7OES5OVg>
CFBE41o M3\HfGZ2dmO2aX;uJGF{e2G7 NX\B[JZLOSEQvF2= M4e3NVI1KGh? Mo\WSG1UVw>? M3X6bXJme3SxcnH0bY9vKG:oIFPGWHIh\GWudHHGOVA5KG23dHHueEB1emGoZnnjb4lv\yC2bzDj[YxtKHO3cn\hZ4Uh[XNiZ3z5Z49nd3Kvcx?= NFvKXlMzOTl6NEm1PC=>
DU145 M3LGU2tqdmG|ZTDBd5NigQ>? NITlSWwzNjVizszN MojQNlQhcA>? NUi5U|I3TE2VTx?= M1vlTGlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyC3cILl[5Vt[XSrb36gc4YheDJzd3HmNUBxem:2ZXnuJIV5eHKnc4Ppc44> Ml\UNlIzPjBzNk[=
DU145 NXHS[mYxU2mwYYPlJGF{e2G7 MUm1JO69VQ>? M{\zNFI1KGh? Mn:xSG1UVw>? MV7Jcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcGm|dH;u[UBJPCCjY3X0fYxifGmxbh?= NGOyfWEzOjJ4MEG2Oi=>
DU145 NV\oNZRRU2mwYYPlJGF{e2G7 NVHNVHY4PSEQvF2= NIfrTWgzPCCq NX7NepI{TE2VTx?= MWjJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcGm|dH;u[UBJOyCqeYDldoFk\XS7bHH0bY9v NFzPXpEzOjJ4MEG2Oi=>
786-0 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWPRRZVZPi5{IN88US=> MmrCO|IhcA>? NHLMdplFVVOR MnX1S2k2OD1|LkKg{txO Mk\JNlI1OzV4Nkm=
A498 NWPzPGJST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITCe243NjJizszN MnSyO|IhcA>? MUTEUXNQ NEG0Oo1IUTVyPUGuOkDPxE1? MWiyNlQ{PTZ4OR?=
A549/ATCC NX\yd2hrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWG2MlIh|ryP M3H2WlczKGh? NHTyUnRFVVOR M3nkTmdKPTB;MT62JO69VQ>? NXHBT3dCOjJ2M{W2Olk>
ACHN MlPRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV3XTXdvPi5{IN88US=> NH7MWoM4OiCq NUDROHB{TE2VTx?= NYj4XJhjT0l3ME2xMlMh|ryP NF72SZUzOjR|NU[2PS=>
BT549 M{P0Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHkOk4zKM7:TR?= MV:3NkBp M2Dkc2ROW09? MXnHTVUxRTFwMzFOwG0> MWqyNlQ{PTZ4OR?=
EKVX M1HRcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3eyOFYvOiEQvF2= M2j2e|czKGh? M{fB[GROW09? MljtS2k2OD1zLkOg{txO NFnJeHUzOjR|NU[2PS=>
HCT15 Mo\lS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NID4Z3c3NjJizszN NHP6fWs4OiCq Mon2SG1UVw>? M{DkWmdKPTB;Mj61JO69VQ>? M2\FW|IzPDN3Nk[5
HOP92 M4GwS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4q1XFYvOiEQvF2= MVS3NkBp MVPEUXNQ M1fvNmdKPTB;NDFOwG0> MoHXNlI1OzV4Nkm=
IGROV1 MkDHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NULSXZdVPi5{IN88US=> MkHQO|IhcA>? MljESG1UVw>? NFjocYhIUTVyPUGuN{DPxE1? MXyyNlQ{PTZ4OR?=
LOXIMVI NEHFToxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlLGOk4zKM7:TR?= NEHEcVI4OiCq MWLEUXNQ NYTMSmpET0l3ME2xJO69VQ>? NYS3ZmtvOjJ2M{W2Olk>
M14 M{TENmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm[wOk4zKM7:TR?= MlrKO|IhcA>? NUfofVFmTE2VTx?= NIP5b|FIUTVyPUGuN{DPxE1? M1;MdVIzPDN3Nk[5
MALME-3M MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkjKOk4zKM7:TR?= M1jKUlczKGh? NITWXVZFVVOR M3nzXGdKPTB;MD6zNkDPxE1? MkHTNlI1OzV4Nkm=
MCF10A MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUTXV|FJPi5{IN88US=> NEOwW4o1QCCq NX7XWIJjTE2VTx?= MXXHTVUxRTlwNjFOwG0> NUXXWmFUOjJ2M{W2Olk>
MDA-MB-435 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYC2MlIh|ryP NEDrWJI4OiCq NUjkPIhnTE2VTx?= MVXHTVUxRTBwNTFOwG0> MlHKNlI1OzV4Nkm=
MDA-MB-468 NYr4TFQxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX6wNlh7Pi5{IN88US=> NX:xTWs1PzJiaB?= NV\TZmFMTE2VTx?= NFXyRnBIUTVyPUCuOlMh|ryP MWCyNlQ{PTZ4OR?=
MOLT4 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NG\Fe2g3NjJizszN MXq3NkBp NXGzbmJRTE2VTx?= NFTOcIJIUTVyPUCuOEDPxE1? Ml7YNlI1OzV4Nkm=
NCI-ADR-RES MnfLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TLb|YvOiEQvF2= MX23NkBp NWC0cmRiTE2VTx?= MXLHTVUxRTBwMU[g{txO NVX2UXE4OjJ2M{W2Olk>
NCI-H23 Ml3FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX:2MlIh|ryP NVfLUIFwPzJiaB?= NFPZZ21FVVOR NUHZU442T0l3ME2xJO69VQ>? MWSyNlQ{PTZ4OR?=
NCI-H322M NXS1U2dRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjNdXE3NjJizszN MXW3NkBp NV3iS3JmTE2VTx?= MU\HTVUxRTBwN{mg{txO MYSyNlQ{PTZ4OR?=
NCI-H460 M4LGTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUW2MlIh|ryP NHPZdYI4OiCq MnHpSG1UVw>? NWfRb4prT0l3ME2wMlc6KM7:TR?= MVKyNlQ{PTZ4OR?=
NCI-H522 Ml7ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2mzSlYvOiEQvF2= NY\yR3RRPzJiaB?= M2nvfWROW09? NIm0UlRIUTVyPUCuOUDPxE1? NYLkToRzOjJ2M{W2Olk>
OVCAR3 MnjHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1exUVYvOiEQvF2= NFv6bos4OiCq MYTEUXNQ NXP5e29HT0l3ME2xMlMh|ryP NX3BWHIxOjJ2M{W2Olk>
OVCAR4 NW[2e49[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rVZlYvOiEQvF2= NFzrNFY4OiCq NIXvVllFVVOR NWnGeJljT0l3ME20JO69VQ>? MUiyNlQ{PTZ4OR?=
OVCAR5 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVO2MlIh|ryP M{fiV|czKGh? M{K4ZWROW09? NXqwN2w2T0l3ME2wMlc6KM7:TR?= NGOxVnMzOjR|NU[2PS=>
OVCAR8 M2rDNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVu2MlIh|ryP M3TDOVczKGh? NESwbnBFVVOR NHzZNGJIUTVyPUCuOUDPxE1? NWXUO|ZWOjJ2M{W2Olk>
RXF393 MoXoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;qS5I3NjJizszN NYLHSI9IPzJiaB?= MoHjSG1UVw>? NVXYT2J6T0l3ME2xMlMh|ryP NY\FPXVqOjJ2M{W2Olk>
SF268 Mlv3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{n2SVYvOiEQvF2= MYO3NkBp M1\l[WROW09? NF;tUpJIUTVyPUGuOkDPxE1? MUOyNlQ{PTZ4OR?=
SF295 MonFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFTpfJk3NjJizszN MUC3NkBp MkP6SG1UVw>? MoXDS2k2OD1zLk[g{txO M{DjO|IzPDN3Nk[5
SF539 M1fZR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TmcVYvOiEQvF2= M17UTVczKGh? MVTEUXNQ NWjxUVhTT0l3ME2yJO69VQ>? M3vNVFIzPDN3Nk[5
SK-MEL-2 MonBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;UV2E2Pi5{IN88US=> M4HXPVczKGh? MXnEUXNQ M3nDeWdKPTB;MT6zJO69VQ>? NYTJVHR[OjJ2M{W2Olk>
SK-MEL-28 M1nUW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLO[lc3NjJizszN MUi3NkBp NILzdI1FVVOR MY\HTVUxRTFizszN NXzOd|V4OjJ2M{W2Olk>
SK-MEL-5 M17DO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2P4cFYvOiEQvF2= NILIdIU4OiCq MnnMSG1UVw>? MX7HTVUxRTBwNkOg{txO M2i2TFIzPDN3Nk[5
SKOV3 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHTSVJA3NjJizszN NFPsPVI4OiCq M1XEZ2ROW09? MmOyS2k2OD1zIN88US=> NH3HU4gzOjR|NU[2PS=>
SN12C NIXVTpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoK0Ok4zKM7:TR?= NWHHV5FGPzJiaB?= MXXEUXNQ MYjHTVUxRTJizszN NFHwSY4zOjR|NU[2PS=>
SNB19 M{XWeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIqwPWI3NjJizszN M1fZ[lczKGh? M{LxO2ROW09? MoLlS2k2OD1yLk[zJO69VQ>? MViyNlQ{PTZ4OR?=
SNB75 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2HieFYvOiEQvF2= M1HCdFczKGh? M{\MPGROW09? MlnHS2k2OD1yLke5JO69VQ>? M3TU[lIzPDN3Nk[5
SR NXfHTotvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYC2MlIh|ryP NEfwTok4OiCq MX\EUXNQ M3;6ZWdKPTB;MD60JO69VQ>? M{K0eVIzPDN3Nk[5
T47D M3XKRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4LqdVYvOiEQvF2= M37IOlczKGh? M1XEcGROW09? NUDJ[3dQT0l3ME2wMlUh|ryP M3X4clIzPDN3Nk[5
TK10 Mor4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGLEb3A3NjJizszN NVzHUpNYPzJiaB?= M4jOVmROW09? NXXLdoQ4T0l3ME2wMlY{KM7:TR?= MkLUNlI1OzV4Nkm=
UACC257 NGjOPWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NED3dWQ3NjJizszN MYO3NkBp NWLTfmoyTE2VTx?= NUn6[FlZT0l3ME2wMlUh|ryP M1XZS|IzPDN3Nk[5
UACC62 MlvnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2TZdlYvOiEQvF2= MlfOO|IhcA>? M4jNVmROW09? MY\HTVUxRTBwNDFOwG0> MV[yNlQ{PTZ4OR?=
UO31 MkS0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1S5OlYvOiEQvF2= MUW3NkBp NIfIUXNFVVOR NITPOZRIUTVyPUCuOUDPxE1? MVmyNlQ{PTZ4OR?=
Hep3B NELQeVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUi0PEBp MmrOSG1UVw>? NEfyUm9IUTVyPUCuOlkh|ryP NGfGXIszOjR|OUi2Ny=>
BE(2)-C MlflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkDLO|IhcA>? M3LB[GROW09? MV7JR|cxRTJizszN NIjwNoszOjl|MkOxOi=>
Bel7402 M37FWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHGO|IhcA>? M1X1[2ROW09? NGPWbXhIUTlyPUG3JO69VQ>? NVnpVYx5OjNyNkGzO|Y>
Bel7404 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfhO|IhcA>? NV;ON45XTE2VTx?= M2PmcGdKQTB;MUig{txO MnXRNlMxPjF|N{[=
BGC823 NX2zbHFiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVu3NkBp M1\yTGROW09? MmP6S2k6OD15LkWg{txO NVLN[3BEOjNyNkGzO|Y>
MGC803 M{jUSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYG4VoZKPzJiaB?= M37YWWROW09? M4HJXWdKQTB;MUCuPEDPxE1? MnywNlMxPjF|N{[=
SGC7901 M17Zemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUTuS4lvPzJiaB?= M2fvNmROW09? NHrwcFZIUTlyPUmuOEDPxE1? Ml[2NlMxPjF|N{[=
SKHEP1 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXOO|IhcA>? M3LNPGROW09? NG\Fd3ZIUTlyPUG3JO69VQ>? Mn3FNlMxPjF|N{[=
SMMC7721 M{jFPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37LWlczKGh? MXrEUXNQ MVnHTVkxRTJyIN88US=> NIL0WmQzOzB4MUO3Oi=>
NUGC3 M1q0VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml64NVAh|ryP NEPOOZVIUT1{Lkm0JO69VQ>? MnfkNlMyPjN|M{K=
A2780 CisR MV;LbY5ie2ViQYPzZZk> MX2xPEBp MXLJcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNESg{txO NHTlPJMzOzJ3Mk[wNy=>
CAL27 sens NHnGWFhMcW6jc3WgRZN{[Xl? NFK4TFgyQCCq MX3Jcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwM{[g{txO NF7seZczOzJ3Mk[wNy=>
CAL27 CisR MYrLbY5ie2ViQYPzZZk> NX21OmZzOThiaB?= NY\OVWp{UW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlYyKM7:TR?= NFzFUpozOzJ3Mk[wNy=>
KYSE-510 CisR M3H3ZWtqdmG|ZTDBd5NigQ>? M4\DU|E5KGh? MUXJcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNUmg{txO M2rxZ|I{OjV{NkCz
KYSE-510 sens MXLLbY5ie2ViQYPzZZk> NVTzZY9qOThiaB?= NVLXdlJEUW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlch|ryP MkXqNlMzPTJ4MEO=
MDA-MB-231 sens NYXRSotFU2mwYYPlJGF{e2G7 MnTuNVghcA>? NHHZSphKdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuOlEh|ryP MlHrNlMzPTJ4MEO=
MDA-MB-231 CisR MXvLbY5ie2ViQYPzZZk> M{XtbVE5KGh? NVfQOGZnUW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlYyKM7:TR?= NHjSRXQzOzJ3Mk[wNy=>
ES2 Mk\ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3fnTFQ5KGh? NXy3XFBCTE2VTx?= M4O0SmlEPTB;MUKuO{DPxE1? M2X3XlI{PDl|NES5
MDA-MB-231 NILNfYlMcW6jc3WgRZN{[Xl? M{jmclExKM7:TR?= MonYN|AhdWmw M3XzNGROW09? MV;Jcohq[mm2aX;uJI9nKEiGQVOyZS=> MYqyN|Q6OzR2OR?=
MDA-MB-231 MlHzT4lv[XOnIFHzd4F6 NEjRVpcyKM7:TR?= Ml;yNlQhcA>? MX\EUXNQ MUfJcohq[mm2aX;uJI9nKEiGQVO2JIF{e2W|c3XkJIF{KGGlZYT5cIF1cW:wIHzleoVteyCxZjD0eYJ2dGmw MmTyNlM1QTN2NEm=
HS68 MWDDfZRwfG:6aXOgRZN{[Xl? MUWxNEDPxE1? NVn4WoNCPzJiaB?= M1TWVWROW09? M2WzUWlEPTB;ND62JO69VQ>? M13LR|I{PTdyNUSy
MEF MWHDfZRwfG:6aXOgRZN{[Xl? MoXXNVAh|ryP MUG3NkBp MVXEUXNQ MVPJR|UxRTRwNDFOwG0> MmW0NlM2PzB3NEK=
BGC823 M1:2Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MknkSG1UVw>? MXLHTVUxRTNwMEmg{txO M{LWXFI{PjBzN{C2
High5 M1vSO2tqdmG|ZTDBd5NigQ>? M2K3PVI1KGh? NV3VZ|l3UW6qaXLpeIlwdiCxZjDoeY1idiC{ZXPvcYJqdmGwdDDISGFEPiC5aYToJGlEPTBib3[gNE4xQSEQvF2= M{i5U|I{PjB{NUKz
High5 MnruT4lv[XOnIFHzd4F6 NFroRY4zPCCq M1eyRmlvcGmkaYTpc44hd2ZiaIXtZY4hemWlb33ibY5idnRiSFTBR|Ehf2m2aDDJR|UxKG:oIECuNVIh|ryP NILwbY8zOzZyMkWyNy=>
High5 MUPLbY5ie2ViQYPzZZk> NFTZSo8zPCCq MoLrTY5pcWKrdHnvckBw\iCqdX3hckBz\WOxbXLpcoFvfCCKRFHDN{B4cXSqIFnDOVAhd2ZiMD6xO{DPxE1? M{P6d|I{PjB{NUKz
A549 NHL5UHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\FSG1UVw>? M3K0SmlEPTB;MT6wO|kh|ryP NV;6bJFMOjN4NESyNVA>
HCT116 MlXFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUWxcWNnTE2VTx?= NFrtVFJKSzVyPUCuO|U4KM7:TR?= NF:xUmozOzZ2NEKxNC=>
K562 MlX5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH3LcmJFVVOR MWTJR|UxRTBwNkS1JO69VQ>? MVeyN|Y1PDJzMB?=
GBC-SD Moe2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVu1JO69VQ>? M{LVNlczKGh? NE[5O49FVVOR MYjJR|UxRTF2Lkig{txO NFvUbWUzOzdyN{K2NC=>
HGC27 NWr0fVkxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIC3PFA2KM7:TR?= NGe4dG44OiCq MojwSG1UVw>? NVHjTnQzUUN3ME21MlQh|ryP MYqyN|cxPzJ4MB?=
HL60 MXzLbY5ie2ViQYPzZZk> NXrK[It[PSEQvF2= NXvld4twOjRiaB?= MVTEUXNQ NWHqZm9UUW6qaXLpeIlwdiCxZjDISGFE MV[yN|cxPzJ4MB?=
Vero MkTXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWq3NkBp MXPEUXNQ M2DWOmlEPTB;MD65JO69VQ>? MXKyN|c5PjR3Mh?=
NCI60 NWDaOnBWS3m2b4TvfIlkKEG|c3H5 M162e|Q5KGh? NWj4OGJDTE2VTx?= NXfGWHBIT0l;MD61N{DPxE1? MmnYNlQxOTV|Mke=
SW620 NGPEWYxEgXSxdH;4bYMhSXO|YYm= NFK0Xog1QCCq M4LkN2ROW09? MnHOS2k:OC53NDFOwG0> NU\uXGIxOjRyMUWzNlc>
U251 M3rLV2N6fG:2b4jpZ{BCe3OjeR?= MYC0PEBp M{TZZ2ROW09? M{nsOGdKRTFwNUOg{txO M{TRZVI1ODF3M{K3
KM12 M2T4ZmN6fG:2b4jpZ{BCe3OjeR?= Mn3mOFghcA>? M1\PZ2ROW09? NYLZcI9zT0l;MT64PEDPxE1? NEjnc24zPDBzNUOyOy=>
Hs578T NYXRUII4S3m2b4TvfIlkKEG|c3H5 M13tOlQ5KGh? NInYeWpFVVOR M4i1XmdKRTRwOEOg{txO MV[yOFAyPTN{Nx?=
MDA-MB-231 NXj0UoE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzuTnY1QCCq NHnSdoVKSzVyPUCuNVYh|ryP M17Z[lI1ODl3MEG2
MCF7 MkK5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYS0PEBp NYKwWnBpT0l;MD60OUDPxE1? M1jRNFI1OTF7NUW1
MDA-MB-435 NXjNNlA3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1rGNFQ5KGh? M2qwT2dKRTBwOEig{txO MX:yOFEyQTV3NR?=
AsPC1 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYKzNEDPxE1? NX\2eIZlPDhiaB?= M3;j[mROW09? MnjkTWM2OD1|Lk[2JO69VQ>? MY[yOFE5PTN5OB?=
Jurkat E6.1 NV3QV4syU2mwYYPlJGF{e2G7 MoDKNkBp MmC4SG1UVw>? NXXSTlRsUW6qaXLpeIlwdiCxZjDISGFEPCC5aYToJGlEPTBib3[gNE4xPCEQvF2= MnPJNlQzPjF6NkK=
KG1 M2S1cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYjMTnAyPDhiaB?= Ml3oTWM2OD1zLkG1JO69VQ>? Ml\UNlQ2OjVyMEO=
HEL MmDpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXK0PEBp NIm2cWJFVVOR NGC4T2pKSzVyPUCuOFkh|ryP NFXXfYIzPDZ7NEC1OS=>
HSC3 MmWyR5l1d3SxeHnjJGF{e2G7 MkP5NVIhcA>? NXe1S29uTE2VTx?= MWTJR|UxRTBwN{Gg{txO NEXnd5YzPDd4NkW2NC=>
HT-29 MmLoR5l1d3SxeHnjJGF{e2G7 NFjaVYYyOiCq NXLn[2hvTE2VTx?= NEC0SlhKSzVyPUCuO|Ih|ryP MWKyOFc3PjV4MB?=
KB MX\DfZRwfG:6aXOgRZN{[Xl? NV\CSXFzOTJiaB?= M{LGb2ROW09? MoPsTWM2OD1yLke1JO69VQ>? M2DSWlI1PzZ4NU[w
H460 NFv3WmREgXSxdH;4bYMhSXO|YYm= MV2xNkBp MoXPSG1UVw>? NYG0fog1UUN3ME2wMlgzKM7:TR?= NFvOSpIzPDd4NkW2NC=>
MONE1 NUjVZVJ1S3m2b4TvfIlkKEG|c3H5 MWWxNkBp MmS4SG1UVw>? MlHpTWM2OD1zLkG4JO69VQ>? NWqyNlgzOjR5Nk[1OlA>
MKN45 NU[3WHRJS3m2b4TvfIlkKEG|c3H5 M33SWVEzKGh? M1TyemROW09? MkLITWM2OD1zLkK1JO69VQ>? M1vUXVI1PzZ4NU[w
TSGH MXrDfZRwfG:6aXOgRZN{[Xl? NFn2fpoyOiCq NVLnU3UxTE2VTx?= MVjJR|UxRTJwMEmg{txO MnzYNlQ4PjZ3NkC=
HL60 M{XmNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEHycYo4OiCq MWjEUXNQ NEjKWmpIUTVyPUCuPVMh|ryP MX:yOFkxODVyMB?=
HEK293 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofJO|IhcA>? NFHXR5pFVVOR Moi2S2k2OD1zMzFOwG0> MkX2NlQ6ODB3MEC=
Jurkat MUPDfZRwfG:6aXOgRZN{[Xl? MXqxNFAh|ryP MYi3NkBp Mni0S2k2OD1yLkmg{txO NEW0elIzPDlyMEe0Ny=>
GM15850 MlGyT4lv[XOnIFHzd4F6 MkniNk42KM7:TR?= M3TTbVk3KGh? NV7FVopJTE2VTx?= M1nnbIRw\XNibn;0JIlvcGmkaYSgTGRCSyCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBpcXO2b37lJGg{KGy7c3nu[UAyPCCjY3X0fYxifGmxbjDv[kBHYE5iZ3Xu[S=> MkXQNVY6OjF|Nke=
GM15850 MkfzT4lv[XOnIFHzd4F6 MlTiNk42KM7:TR?= NX7ycnJwQTZiaB?= M176TGROW09? MWjkc4V{KG6xdDDpcohq[mm2IFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgOUBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= MWqxOlkzOTN4Nx?=
GM15850 NWHER2Z{U2mwYYPlJGF{e2G7 NVftb2pHOi53IN88US=> MofYPVYhcA>? NWDNcm4xTE2VTx?= NW\zTow{\G:nczDuc5QhcW6qaXLpeEBJTEGFIHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKGirc4TvcoUhUDRibInzbY5mKDF{IHHj[ZR6dGG2aX;uJI9nKE[[TjDn[Y5m MmPSNVY6OjF|Nke=
GM15850 NH;uZlFMcW6jc3WgRZN{[Xl? NH7Fb2kzNjVizszN MWW5OkBp M3XYUmROW09? NEnNUZpld2W|IH7veEBqdmirYnn0JGhFSUNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hcGm|dH;u[UBJOyCueYPpcoUhQSCjY3X0fYxifGmxbjDv[kBHYE5iZ3Xu[S=> MWWxOlkzOTN4Nx?=
GM15850 NF7rb29McW6jc3WgRZN{[Xl? MXiyMlUh|ryP NIjKUmo6PiCq MUHEUXNQ NIDTd|Fld2W|IH7veEBqdmirYnn0JGhFSUNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hcGm|dH;u[UBJPCCueYPpcoUhQCCjY3X0fYxifGmxbjDv[kBHYE5iZ3Xu[S=> NVXzWJVUOTZ7MkGzOlc>
GM15850 MlXMT4lv[XOnIFHzd4F6 MV6yMlUh|ryP NEP3Tnk6PiCq M3excWROW09? MXvkc4V{KG6xdDDpcohq[mm2IFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgNVYh[WOndInsZZRqd25ib3[gSnhPKGenbnW= NYXFfINwOTZ7MkGzOlc>
GM15850 NFy0PG5HfW6ldHnvckBCe3OjeR?= MX[1JO69VQ>? NIjuVpIyOiCq M{PR[GROW09? NXLEXnZRcGG|IH7vJIVn\mWldDDvckBHYE5ibWLORUBmgHC{ZYPzbY9v NGH6RmsyPjl{MUO2Oy=>
U937 Moi4T4lv[XOnIFHzd4F6 NFfte4o2KM7:TR?= NXHKPY5VOjRiaB?= NF\yb2xFVVOR M33BeIhieyCwbzDl[oZm[3Rib36gZYxxcGFidIXieYxqdiCjY3X0fYxifGmxbh?= NUPWOpZ{OTd2NEe3OVA>
U937 M3\tTmtqdmG|ZTDBd5NigQ>? Mmi1NUDPxE1? MVSyOEBp Mkn2SG1UVw>? NUCyUlFHcGG|IH7vJIVn\mWldDDvckBidHCqYTD0eYJ2dGmwIHHj[ZR6dGG2aX;u NV7DXWIzOTd2NEe3OVA>
PANC1 MWXGeY5kfGmxbjDBd5NigQ>? NHXxUFcyKM7:TR?= NFv0NHczPCCq NXTNc4NT\G:nczDuc5QhcW6lcnXhd4UhcW5icEK3b4lxOSCpZX7lJIV5eHKnc4Ppc44> NWjoNpgyOTd3OEi3OFQ>
PANC1 M3XubWZ2dmO2aX;uJGF{e2G7 M3X1RlEh|ryP M37pflQ5KCCq MYHkc4V{KG6xdDDpcoNz\WG|ZTDpckBxOjetaYCxJIdmdmViZYjwdoV{e2mxbh?= M{XyXFE4PTh6N{S0
Caco-2 MoDLSpVv[3Srb36gRZN{[Xl? MYi1JO69VQ>? NXzJSot5OjRiaB?= M132OGROW09? NVLZV45M\G:nczDuc5QhcW6mdXPlJHAzOVeDRkGg[4Vv\SCneIDy[ZN{cW:w MVGyNFE1Ozh2MB?=
SCC4 NHvWeVZHfW6ldHnvckBCe3OjeR?= NFexbmgyKM7:TR?= NYHmNpZVOTBibXnu MYjEUXNQ M2KxPIhieyCwbzDh[49vcXO2IHHjeIl3cXS7IHH0JHZFWiCjc4Pld5Nm\CCjczDpcoR2[3Srb36gc4YhS1mSMkSg[4Vv\SCneIDy[ZN{cW:w M4D2dFIxPDV{MkK1
A549 Mmf5SpVv[3Srb36gRZN{[Xl? MmLrOUDPxE1? NWKxUGxzOyCq NWi3enNKTE2VTx?= MVfkc4V{KG6xdDDpcoR2[2ViYYX0c5Bp[We7IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKEyFM1nJ NH7aeXozODh3NUKwPC=>
HCT116 Mo\qT4lv[XOnIFHzd4F6 MknPNE4{KM7:TR?= NF;IXlY{OCCq MlvKSG1UVw>? M1e0NoRw\XNibn;0JIlvcGmkaYSgTGRCSzFiYYPz[ZN{\WRiYYOgbY5lfWO2aX;uJI9nKGirc4TvcoUhUDONOTDhZ4V1gWyjdHnvci=> NXHaTIpTOjFyOEC2OFc>
HepG2 NIrLV5lHfW6ldHnvckBCe3OjeR?= Mn;YNVAh|ryP NX3jR5BmOjRiaB?= M13JRmROW09? M1TPc4Rw\XNibn;0JIlv\HWlZTDhdI9xfG:|aYOgZZN{\XO|ZXSgZZMhcHmyZYLhZ4V1gWyjdHnvckBw\iCyNUO= MoDkNlE2PDh3OEK=
GM11272 MlH4SpVv[3Srb36gRZN{[Xl? MV2wMlEh|ryP NF\IN484OiCq NEH3T|lFVVOR NHf6[5pld2W|IH7veEBz\WGldHn2ZZRmKE2nQ4CyJI12fGGwdDDlfJBz\XO|aX;u NUPiWVAzOjF6NEC3NVY>
MDA-MB-231 M{\kOGtqdmG|ZTDBd5NigQ>? M1zKSlExKM7:TR?= M4\4eFUhdWmw NF\6NG9FVVOR M1vOPYRw\XNibn;0JIlvcGmkaYSgTGRCSzKj NH7SPXMzOzR7M{S0PS=>
MDA-MB-231 MnvsT4lv[XOnIFHzd4F6 NIH3NGQyKM7:TR?= NUPsOHl7OjRiaB?= MWHEUXNQ M4\iS4Rw\XNibn;0JIlvcGmkaYSgTGRCSzZiYYPz[ZN{\WRiYYOgZYNmfHmuYYTpc44hdGW4ZXzzJI9nKHS3YoXsbY4> NIq3UGEzOzR7M{S0PS=>
K562 MVzLbY5ie2ViQYPzZZk> MVXkc4V{KG6xdDDpcohq[mm2IFjERWM> NVnJVJl[OjN3OUGxNVE>
Jurkat MUTDfZRwfG:6aXOgRZN{[Xl? NWO4bppLOjBizszN M4Ox[FczKGh? MVHEUXNQ MkHJco8h[3m2b4TvfIlkcXS7IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;u M{fOZVI1OzB2M{S4
HCT116 M1nMTWFxd3C2b4Ppd{BCe3OjeR?= MUSzJO69VQ>? MmXqNlQhcA>? NYLJRWdpTE2VTx?= NIriXXFld2W|IH7veEBqdmS3Y3WgZZBweHSxc3nzJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIIC1N{Bxem:2ZXnuJIxmfmWu MkHWNlQ4PjZ3NkC=
KASUMI-1 Mo\yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWD6fpg4UUN3ME25PU4yPyCwTR?= NF7zZlNUSU6JRWK=
KARPAS-45 NGrCWIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MU\JR|UxRTF5Mz64PUBvVQ>? MV3TRW5ITVJ?
BHT-101 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjUTmJKSzVyPUK0OE4yQCCwTR?= MWPTRW5ITVJ?
H9 NVjVWZhPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NY\hVZIxUUN3ME2yOVUvODRibl2= MYnTRW5ITVJ?
PA-1 M3\jZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoTsTWM2OD1{OE[uNlYhdk1? M{e2fnNCVkeHUh?=
NEC8 NVXzd2o4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zQOmlEPTB;Mki5MlM5KG6P MWTTRW5ITVJ?
MHH-PREB-1 NFjXenBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4nyN2lEPTB;Mkm0MlU{KG6P MmrGV2FPT0WU
NB7 M4HrTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnvyTWM2OD1|NEWuO|Qhdk1? MWHTRW5ITVJ?
A3-KAW MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYi1bY1rUUN3ME20NFAvPTlibl2= NEXkSmdUSU6JRWK=
NB69 NU\pdIs6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHsTWM2OD12MUGuO|Ehdk1? MUjTRW5ITVJ?
EoL-1-cell NG\XSVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4DGTWlEPTB;NEW0NlUhdk1? NU\ie4VnW0GQR1XS
CHP-212 Mli1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mk\ETWM2OD12NUeuOVMhdk1? M1e4WHNCVkeHUh?=
C2BBe1 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF7TNIRKSzVyPUS3Nk4yQSCwTR?= NFftfmhUSU6JRWK=
697 M2i5bWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTR5Mz60NUBvVQ>? MUDTRW5ITVJ?
BCPAP MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWXnUWFQUUN3ME21NFEvPDJibl2= NHzOb|dUSU6JRWK=
L-363 NGnhdoxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fMW2lEPTB;NUCzMlEhdk1? Mn;RV2FPT0WU
ES8 NELuXJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIPrTIVKSzVyPUWyN{42OyCwTR?= MV3TRW5ITVJ?
BE-13 M2W3V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnTlTWM2OD13Mk[uPVYhdk1? NUT3[WNMW0GQR1XS
CTB-1 M{XhVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnRV|ltUUN3ME21N|cvQTJibl2= M3TscnNCVkeHUh?=
HD-MY-Z NFTaPFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4qwUmlEPTB;NUO4MlE{KG6P NGnNU|BUSU6JRWK=
NKM-1 NEDIWVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2TKb2lEPTB;NUS0MlI4KG6P NEHHd29USU6JRWK=
NCI-H720 MoO3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnKU3FKSzVyPUW2NE4yQCCwTR?= MXLTRW5ITVJ?
KY821 M{TLT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHjZ[nJKSzVyPUW2N{4zPSCwTR?= MV\TRW5ITVJ?
OVCAR-5 NV[1dZE1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTV5Nj6xNUBvVQ>? M4LFdHNCVkeHUh?=
CTV-1 M2\0bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUTJR|UxRTV6MT61OkBvVQ>? NFnMfJpUSU6JRWK=
P12-ICHIKAWA MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGr3dIVKSzVyPUW5Ok42OSCwTR?= MWrTRW5ITVJ?
DB NH;TWpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmKzTWM2OD13OUiuOVchdk1? NUPWelhFW0GQR1XS
CHL-1 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTZ2Mj6wPEBvVQ>? NW\COpZlW0GQR1XS
A4-Fuk NFmyS21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFrNfnpKSzVyPU[0OE46OSCwTR?= MmnhV2FPT0WU
MV-4-11 M4jwOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LFeWlEPTB;NkW5MlEhdk1? NF;Vc3ZUSU6JRWK=
RPMI-8226 MkjXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NELyfG9KSzVyPU[3PE4yQCCwTR?= NFHGNYNUSU6JRWK=
NB14 MmniS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY[yfVBmUUN3ME22PVYvQTVibl2= MoT4V2FPT0WU
DOHH-2 M1PVU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlrETWM2OD15ME[uOlghdk1? NYe5c2VFW0GQR1XS
D-423MG NGjpWlZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHPTWM2OD15ME[uPFkhdk1? NXm2[nd{W0GQR1XS
D-283MED MkLvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInlOlVKSzVyPUexOE4yPCCwTR?= NVfMcGlJW0GQR1XS
ES1 NWPOWIJmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml3PTWM2OD15MkSuOEBvVQ>? M1HKUnNCVkeHUh?=
GOTO MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHUTWM2OD15MkmuNVIhdk1? NUXrZlFLW0GQR1XS
NCI-H209 M4fEXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37IbmlEPTB;N{K5Mlkhdk1? M1XDfHNCVkeHUh?=
MOLT-13 NHqwV5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUW4UIt2UUN3ME23N|gvQThibl2= NVqwOnp2W0GQR1XS
ATN-1 NW\GO4syT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHfnellKSzVyPUe0NE4zQCCwTR?= MlvTV2FPT0WU
DU-4475 NX3JZYpRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTd3MT65NUBvVQ>? MoPUV2FPT0WU
NB10 NXfWeHF6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{nneWlEPTB;N{WxMlkzKG6P NIjlUVNUSU6JRWK=
KG-1 MmrmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{nTcGlEPTB;N{e1MlQ2KG6P NE\NZ2xUSU6JRWK=
MOLT-4 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTd6Nz60OkBvVQ>? NVftT3E{W0GQR1XS
TE-1 NUDSe4JoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFvBcWlKSzVyPUe5NU4yKG6P NG\5cJVUSU6JRWK=
SBC-1 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvtTWM2OD15OUOuPFQhdk1? NE\zN|ZUSU6JRWK=
HEL NGLn[lRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmTITWM2OD16ME[uNFghdk1? NVfr[nFmW0GQR1XS
SK-MEL-2 NIizVmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYCxPZF5UUN3ME24NFkvPDRibl2= NYHYWWhNW0GQR1XS
KU812 NEHIW4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIftOotKSzVyPUixN{4yKG6P NGjRSJhUSU6JRWK=
RPMI-8866 M2\NWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFXPfpFKSzVyPUixN{43PyCwTR?= MkXCV2FPT0WU
ALL-PO MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX7JR|UxRThzND62OkBvVQ>? MYjTRW5ITVJ?
LU-139 NUO4flZKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{TlN2lEPTB;OEKyMlg3KG6P M4rBTnNCVkeHUh?=
RS4-11 MljMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnLtTWM2OD16M{KuOFUhdk1? M2LmcnNCVkeHUh?=
EW-18 NF[x[IxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjXWpdwUUN3ME24N|IvQTZibl2= MmLwV2FPT0WU
P30-OHK MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2C2R2lEPTB;OEO1Mlchdk1? MWHTRW5ITVJ?
D-566MG NE\KTGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\HTWM2OD16M{iuOlIhdk1? NID3eYVUSU6JRWK=
HSC-4 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTh2Nj61NUBvVQ>? M{XXXnNCVkeHUh?=
QIMR-WIL M3m4VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTh4Mj6wN{BvVQ>? M4jmW3NCVkeHUh?=
SW954 NXTBd40{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXW4[pRmUUN3ME24OlMvOTZibl2= NWXnWVZvW0GQR1XS
HGC-27 NI\DVHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGq0[IdKSzVyPUi3Nk4{PCCwTR?= MkTPV2FPT0WU
HH Mn65S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;aTWM2OD16OUSuNVIhdk1? MXPTRW5ITVJ?
KE-37 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2XjXGlEPTB;OEm0MlYzKG6P NEjIXpVUSU6JRWK=
SK-N-DZ M2HQUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTlyMD60N{BvVQ>? M4rwVnNCVkeHUh?=
J-RT3-T3-5 NEPESnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlzkTWM2OD17MUCuOFkhdk1? MWHTRW5ITVJ?
A427 NELwSW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{OyZmlEPTB;OUKwMlg1KG6P MonOV2FPT0WU
ECC10 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrsdnVKSzVyPUm0OU45PyCwTR?= MnnQV2FPT0WU
EW-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLLOpBOUUN3ME25OFcvOjZibl2= NEfCdJNUSU6JRWK=
MIA-PaCa-2 NEHRc5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1vpW2lEPTB;OUS5MlEzKG6P MmrnV2FPT0WU
HCC2218 Mk\1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnfCTWM2OD17NUiuOFghdk1? M3fvV3NCVkeHUh?=
HAL-01 M33HfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTl4OD6wOEBvVQ>? NV;2PWp6W0GQR1XS
RD MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGP4TnVKSzVyPUm3OE41PSCwTR?= MYrTRW5ITVJ?
SK-N-AS MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnYV2NKSzVyPUm4PE4yKG6P NW\Q[YN[W0GQR1XS
ML-2 MoPFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1[wO2lEPTB;MT6wNFQxPyEQvF2= NIfTV4ZUSU6JRWK=
MEL-HO MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\QTWM2OD1zLkCwOVgzKM7:TR?= MoLSV2FPT0WU
MS-1 NYHyPGNwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH7kZ2hKSzVyPUGuNFA3OTdizszN MkHVV2FPT0WU
NCI-SNU-1 NFnSSYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIS4OJpKSzVyPUGuNFI{OzFizszN MX;TRW5ITVJ?
8505C NH;kNXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnnuTWM2OD1zLkCyN|MyKM7:TR?= MUDTRW5ITVJ?
MN-60 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2LQUmlEPTB;MT6wNlY5KM7:TR?= MXvTRW5ITVJ?
SAS NGDTW|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVTJR|UxRTFwMESwPFEh|ryP MXrTRW5ITVJ?
EFM-19 MmLhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXLJR|UxRTFwMES4O|kh|ryP MXXTRW5ITVJ?
Ca9-22 NGmzU|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX7sRnFpUUN3ME2xMlA2OTB5IN88US=> NFv1U2xUSU6JRWK=
NBsusSR NIjnVoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFjYNnlKSzVyPUGuNFUyPjZizszN MX7TRW5ITVJ?
NB13 MnfNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnxcYVKSzVyPUGuNFU2ODFizszN NVfuTppIW0GQR1XS
SF295 NF31N5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTFwME[2NlQh|ryP M3zwOHNCVkeHUh?=
U-2-OS Mo\HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTFwMEe5NVEh|ryP MVTTRW5ITVJ?
NCI-H526 M1;jdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2fqW2lEPTB;MT6wPFI6OSEQvF2= NVPkfHhMW0GQR1XS
KMOE-2 MkHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTFwMEm0NlIh|ryP NX:3U5lGW0GQR1XS
RCM-1 Mo\IS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUDJR|UxRTFwMUKxNFIh|ryP MYTTRW5ITVJ?
MC116 NGTkTIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M37KVWlEPTB;MT6xN|YzOSEQvF2= MUHTRW5ITVJ?
NCI-H1092 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml:3TWM2OD1zLkG1OFA3KM7:TR?= NGLMO2JUSU6JRWK=
EW-3 Ml7nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mkn1TWM2OD1zLkG3NlEzKM7:TR?= NHW4SFFUSU6JRWK=
HCT-116 M{\qfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTFwMUe3OUDPxE1? NUX2ZVdMW0GQR1XS
MC-IXC M1XwSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4\0dGlEPTB;MT6xO|g5OSEQvF2= MVfTRW5ITVJ?
LB1047-RCC M1;teWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYXxT2lHUUN3ME2xMlE5OzF{IN88US=> M4L5fHNCVkeHUh?=
VM-CUB-1 M1;Oe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEm3UYZKSzVyPUGuNVkyODhizszN NWftZ|JZW0GQR1XS
NB5 NWLEN5JZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXjafIxQUUN3ME2xMlE6QDV4IN88US=> MVPTRW5ITVJ?
SKG-IIIa Mn[5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTFwMkO0OlQh|ryP Moq4V2FPT0WU
HO-1-N-1 MlHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{juPWlEPTB;MT6yN|g{PSEQvF2= NF\Z[VdUSU6JRWK=
EFO-27 NF74VWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnLkTWM2OD1zLkK1NFQ{KM7:TR?= NWrRUVJEW0GQR1XS
MHH-NB-11 M1z6bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTFwMkizNlkh|ryP MUHTRW5ITVJ?
SW620 M3LmTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmC3TWM2OD1zLkK5NFE5KM7:TR?= NUPUZYxDW0GQR1XS
MOLT-16 NYX3dGluT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTFwMkm3PVch|ryP NFjCSIJUSU6JRWK=
NTERA-S-cl-D1 NHHBXZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4T5NGlEPTB;MT6zNVc3OSEQvF2= NHjpS3lUSU6JRWK=
VA-ES-BJ MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXvxSZhmUUN3ME2xMlMzPDd5IN88US=> MUfTRW5ITVJ?
HCC1419 NVT0OGdpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4XBfGlEPTB;MT6zOFAzPyEQvF2= MYfTRW5ITVJ?
NCI-H69 NITKOWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkTWTWM2OD1zLkO0NVEzKM7:TR?= MXTTRW5ITVJ?
DEL NYe3OVVjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\Ec3NGUUN3ME2xMlM2OTZ{IN88US=> MXrTRW5ITVJ?
LXF-289 NVXTTZlYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEHtXFNKSzVyPUGuN|UzPCEQvF2= Mn3lV2FPT0WU
EW-11 NEniT|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWrDWnM2UUN3ME2xMlM3ODJ4IN88US=> NGTLUGpUSU6JRWK=
KP-4 NILxXIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fLemlEPTB;MT6zO|A5PSEQvF2= Mki0V2FPT0WU
NOS-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NI[x[HFKSzVyPUGuOFEyQTRizszN MV3TRW5ITVJ?
SK-NEP-1 MkHvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJR|UxRTFwNEG2PVMh|ryP M3u3XXNCVkeHUh?=
LAMA-84 NWDONVhPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTFwNEO5OFUh|ryP MlS3V2FPT0WU
ES5 NFW1cnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnxO4pbUUN3ME2xMlQ1OyEQvF2= M4PTS3NCVkeHUh?=
HuO9 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH6xVmxKSzVyPUGuOFU{PjJizszN MYjTRW5ITVJ?
COLO-684 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIXTTYNKSzVyPUGuOFYyOThizszN MlvkV2FPT0WU
EW-24 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUDVT5BQUUN3ME2xMlQ3PTNzIN88US=> MkntV2FPT0WU
BV-173 MorxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHLaVmdKSzVyPUGuOFczQTFizszN MX\TRW5ITVJ?
NCI-H1770 NEDLOHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX7JR|UxRTFwNEi1N|Yh|ryP MkXZV2FPT0WU
HuP-T4 MkHjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mke4TWM2OD1zLkS5N{DPxE1? M1j6VHNCVkeHUh?=
TYK-nu NV\zVno3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTFwNEm4OVEh|ryP MXXTRW5ITVJ?
YH-13 NF;kflRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIixeWtKSzVyPUGuOFk5QTRizszN Ml;DV2FPT0WU
H4 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfYSGVKSzVyPUGuOVA6OTJizszN MXLTRW5ITVJ?
OVCAR-8 MoS0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mlq4TWM2OD1zLkW0OFc4KM7:TR?= Mle4V2FPT0WU
NCI-H23 NGP0V3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHVZldKSzVyPUGuOVQ3PDVizszN NF[yemxUSU6JRWK=
ES7 NXzEWnJWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2S1XmlEPTB;MT61OFc4OyEQvF2= M1\0XnNCVkeHUh?=
COR-L88 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NITYN3BKSzVyPUGuOVY1OjRizszN NXn3eYxjW0GQR1XS
TI-73 NHzudXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUPpelJtUUN3ME2xMlU6ODZizszN MoThV2FPT0WU
RT-112 NEjOUYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTjS5FIUUN3ME2xMlU6Ojh2IN88US=> M{Cy[XNCVkeHUh?=
HuO-3N1 NX7DT5lOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFm1[nJKSzVyPUGuOVk{QDVizszN MkTMV2FPT0WU
HC-1 Mk[5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MljLTWM2OD1zLkW5PFY3KM7:TR?= MVzTRW5ITVJ?
HT55 NX\rSHZPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTFwNkWxN|Eh|ryP M2HvRXNCVkeHUh?=
IA-LM M4TQZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTFwNkmyO|gh|ryP MV3TRW5ITVJ?
EM-2 M3PoVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFX2e2tKSzVyPUGuO|AxOTRizszN MWHTRW5ITVJ?
MHH-ES-1 NYjPNFFFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M32yRWlEPTB;MT63NFQ{PSEQvF2= MkL1V2FPT0WU
CAL-27 MkPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkfuTWM2OD1zLkewOlIyKM7:TR?= MlHVV2FPT0WU
COLO-800 M3ztRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX7wfnh1UUN3ME2xMlcyOTd7IN88US=> M{fUcnNCVkeHUh?=
HCE-T MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVXJR|UxRTFwN{G1JO69VQ>? Ml[yV2FPT0WU
CAMA-1 Mnv5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NETiV2hKSzVyPUGuO|E6PzFizszN M4\zVHNCVkeHUh?=
LOXIMVI MkPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYXJR|UxRTFwN{KxNUDPxE1? NX\S[lV3W0GQR1XS
NH-12 M{n5RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlnsTWM2OD1zLkeyOlkyKM7:TR?= NX;sRng{W0GQR1XS
TCCSUP MmTuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFnHN2JKSzVyPUGuO|I5OjlizszN M1S0U3NCVkeHUh?=
MDA-MB-361 M37hNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWHMWoEzUUN3ME2xMlc{OTV5IN88US=> NEjEeYxUSU6JRWK=
EW-16 NHz3eGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnryTWM2OD1zLke0NVA4KM7:TR?= MVTTRW5ITVJ?
SNU-423 NIjuTnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnyyTWM2OD1zLke1PFI4KM7:TR?= NIP3d3VUSU6JRWK=
Daoy M2nMZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NInhT2tKSzVyPUGuO|Y{OTlizszN MmHHV2FPT0WU
ES4 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zMRmlEPTB;MT63PFc1OSEQvF2= NFzCXopUSU6JRWK=
PFSK-1 MkG0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFzPfGZKSzVyPUGuPFA{PyEQvF2= MXzTRW5ITVJ?
ES3 NHez[5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTFwOEK2PFEh|ryP NIOwRZdUSU6JRWK=
ONS-76 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVe0WFNRUUN3ME2xMlgzQDl5IN88US=> M2DGfHNCVkeHUh?=
JVM-3 MlHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTFwOEW0OVEh|ryP NHrmdZpUSU6JRWK=
OS-RC-2 NH35b3ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnnsTWM2OD1zLki3NVUyKM7:TR?= M4LTTXNCVkeHUh?=
COLO-320-HSR NGrmcphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTFwOEixPVch|ryP M1vhXHNCVkeHUh?=
HN MnWwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYnJR|UxRTFwOEi3NlUh|ryP MnO1V2FPT0WU
HT M{XUZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXXHOnp[UUN3ME2xMlg5QTR5IN88US=> M1vEWnNCVkeHUh?=
LoVo MnXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYTJR|UxRTFwOEm4NUDPxE1? MoPDV2FPT0WU
CGTH-W-1 M3XBVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIHMXllKSzVyPUGuPFk6PDZizszN M{n5cXNCVkeHUh?=
NB6 Mke5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVqyUZBTUUN3ME2xMlkyOjl6IN88US=> M1jLVHNCVkeHUh?=
EW-22 NFfGfXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIXrPZdKSzVyPUGuPVI5QDdizszN MVPTRW5ITVJ?
ES6 NXvvfGY5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTFwOUO2N|Eh|ryP NEfhbnVUSU6JRWK=
SCC-15 NV\SVJZOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTFwOUO4NVkh|ryP NGftVJdUSU6JRWK=
HL-60 Mmn3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYHJR|UxRTFwOUO5NFIh|ryP NIW0enhUSU6JRWK=
human HOP-92 Mlj3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHGfZRKSzVyPUGuPVQxPjVizszN MnzoV2FPT0WU
SW626 NY\Ncml5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWXlWlZlUUN3ME2xMlk1QDl7IN88US=> NH7MVIRUSU6JRWK=
HEC-1 NEPrWIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHi0b|dKSzVyPUGuPVU{PiEQvF2= NV30eGNIW0GQR1XS
LB2241-RCC NWCzS|BkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1LQR2lEPTB;MT65PFI{OSEQvF2= NInQeoJUSU6JRWK=
Ramos-2G6-4C10 NYHyfZRwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHQTWM2OD1zLkm5OFk{KM7:TR?= MkLhV2FPT0WU
A101D NWnnNWJsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYfMWpdkUUN3ME2yMlIxOzB|IN88US=> NY[xTXJsW0GQR1XS
NCI-H446 NWTwd2R3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDZTWM2OD1{LkC0OVk6KM7:TR?= MVfTRW5ITVJ?
SBC-5 M4[5Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TPNWlEPTB;Mj6wOlE1PyEQvF2= NYTK[XNEW0GQR1XS
HOS MlPMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M136SGlEPTB;Mj6wO|Y2OyEQvF2= MmnUV2FPT0WU
K5 NFm3cWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYDJR|UxRTJwMEe4NVEh|ryP NYLLd2NmW0GQR1XS
HLE MljZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmSxTWM2OD1{LkC4OVI6KM7:TR?= NEO3ZYFUSU6JRWK=
HSC-2 NFvXNHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NULGUIluUUN3ME2yMlEzQDl6IN88US=> MVfTRW5ITVJ?
LCLC-97TM1 NWnj[5hQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFPGNY5KSzVyPUKuNVQ2QDNizszN MXTTRW5ITVJ?
DMS-273 NEnvNIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDIfppKSzVyPUKuNVQ5OzdizszN M13mUXNCVkeHUh?=
TE-8 M3rNTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV;ZbI5QUUN3ME2yMlE2PzZ3IN88US=> NU\2cpZSW0GQR1XS
DSH1 NH62d|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4P4XmlEPTB;Mj6xOlM6QCEQvF2= NWDsWlQ6W0GQR1XS
CAL-51 Mk\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfPfVZYUUN3ME2yMlE3Pjl7IN88US=> MVXTRW5ITVJ?
IST-SL1 NV;MUFE1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoLBTWM2OD1{LkG2PFQ1KM7:TR?= MWfTRW5ITVJ?
GCT MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTJwMUe3O{DPxE1? MmDsV2FPT0WU
SW948 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYf6WG4{UUN3ME2yMlE5PDV4IN88US=> M1L1PHNCVkeHUh?=
NOMO-1 MnfvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnraTWM2OD1{LkG5N|E4KM7:TR?= NUHKdoRGW0GQR1XS
C8166 M{jhfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXPJR|UxRTJwMkGzN|Qh|ryP NYXQd3NEW0GQR1XS
OC-314 M375Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfqWmN6UUN3ME2yMlI{OjV7IN88US=> MnW5V2FPT0WU
CAL-39 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NU\qOG5KUUN3ME2yMlI{PjJ4IN88US=> MU\TRW5ITVJ?
MDA-MB-453 MnfhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPrTWM2OD1{LkK0Nlc2KM7:TR?= MlTBV2FPT0WU
A673 MorQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\Eb2lEPTB;Mj6yOVg3OiEQvF2= M{\rT3NCVkeHUh?=
HTC-C3 NGXGOJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTJwMk[4OUDPxE1? NEfKZndUSU6JRWK=
NCI-H1666 MmXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXzBXpFWUUN3ME2yMlI5OTFzIN88US=> M2rYSHNCVkeHUh?=
PSN1 MkfnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTJwMki5NVMh|ryP MUHTRW5ITVJ?
GI-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUjJR|UxRTJwM{C1OFMh|ryP M4W4fXNCVkeHUh?=
HuH-7 M1u0Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvaR|lKSzVyPUKuN|A3OzdizszN MkjZV2FPT0WU
JAR M3fkbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWHJR|UxRTJwM{G5PFch|ryP MWLTRW5ITVJ?
5637 NGLYR|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2X2UGlEPTB;Mj6zNlEzQSEQvF2= MmnjV2FPT0WU
GB-1 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTJwM{KzN|Uh|ryP MnGyV2FPT0WU
KP-N-YS Mo[1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MknyTWM2OD1{LkOyOlE2KM7:TR?= Ml\IV2FPT0WU
OAW-42 M{PqW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWjrN4RFUUN3ME2yMlM{PDF4IN88US=> NXjKOoVkW0GQR1XS
8-MG-BA NHPWWFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NI\NUIlKSzVyPUKuN|M6ODZizszN M2G1U3NCVkeHUh?=
RH-18 NHTtUYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYLJR|UxRTJwM{WwNlIh|ryP NGPyNIJUSU6JRWK=
NCI-H1155 NWDFSZM6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH2wfI9KSzVyPUKuN|Y4OjVizszN M2LVeHNCVkeHUh?=
NB17 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NInLUXVKSzVyPUKuN|gzPDNizszN MnjUV2FPT0WU
NCI-H1437 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlr1TWM2OD1{LkSxPFc{KM7:TR?= M3nUdXNCVkeHUh?=
SN12C M4DITmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTJwNEOyNVQh|ryP Mn3sV2FPT0WU
HSC-3 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXe3S3VvUUN3ME2yMlQ1PTB7IN88US=> MV;TRW5ITVJ?
GAMG NEGxUIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmTjTWM2OD1{LkS0OVYyKM7:TR?= MluyV2FPT0WU
HT-1080 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWPNbGhCUUN3ME2yMlQ1QDZ2IN88US=> MoS1V2FPT0WU
A549 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWjCUGhrUUN3ME2yMlQ1QDl|IN88US=> MnPGV2FPT0WU
KNS-62 M3\vb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4fsV2lEPTB;Mj60OVA3OSEQvF2= MoDlV2FPT0WU
YKG-1 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnv4TWM2OD1{LkS1OFM4KM7:TR?= MnvEV2FPT0WU
LU-134-A MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDEZYg3UUN3ME2yMlQ4ODB6IN88US=> M3XZ[3NCVkeHUh?=
FADU M3\0eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTJwNEexOlIh|ryP NWTpbGpJW0GQR1XS
TGBC11TKB NW\CdlNGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPafmoxUUN3ME2yMlQ4OTd5IN88US=> NH\TU|NUSU6JRWK=
HT-3 M3TiTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVruZXVVUUN3ME2yMlQ6PTN3IN88US=> MVTTRW5ITVJ?
NCI-H2170 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7hTWM2OD1{LkWwOVQ6KM7:TR?= M2\VSnNCVkeHUh?=
Mo-T NF7IWoxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1fCcWlEPTB;Mj61NFkzPyEQvF2= NYnwb2hTW0GQR1XS
CCRF-CEM M{S2Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1rXd2lEPTB;Mj61N|A1OyEQvF2= MVjTRW5ITVJ?
KU-19-19 M3qw[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTJwNUO1NVMh|ryP MWnTRW5ITVJ?
NCI-H1048 NV:xU5d5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3PJVmlEPTB;Mj61OVAzPSEQvF2= MmPQV2FPT0WU
KOSC-2 M2XXRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{exZ2lEPTB;Mj61OlA4PiEQvF2= M3PNNHNCVkeHUh?=
A431 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWLEcFZDUUN3ME2yMlU3OzN3IN88US=> M3\4[HNCVkeHUh?=
COR-L23 M4fqO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3vJSGlEPTB;Mj61PFU3PiEQvF2= NFLlT|BUSU6JRWK=
MKN28 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4DXW2lEPTB;Mj61PVA{PyEQvF2= M1j3bnNCVkeHUh?=
22RV1 M4rGOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnS1TWM2OD1{LkW5Nlc1KM7:TR?= M4PNcHNCVkeHUh?=
ABC-1 NUPWU5g4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fVOmlEPTB;Mj62NFQ3KM7:TR?= NEflTHZUSU6JRWK=
NCI-H2126 Mn;mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmHkTWM2OD1{Lk[wPVg1KM7:TR?= MYHTRW5ITVJ?
DoTc2-4510 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjaTWM2OD1{Lk[yNVg2KM7:TR?= M4\ZVXNCVkeHUh?=
SCC-4 NHTudZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFL2eIlKSzVyPUKuOlMxOTJizszN NIrmZ5NUSU6JRWK=
NCI-H661 NIHqcnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGSwN4dKSzVyPUKuOlQxQDVizszN M1i5SXNCVkeHUh?=
RPMI-2650 MnnLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTJwNkSxOFMh|ryP NI\0UHpUSU6JRWK=
NCI-H510A NIHIbGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTJwNkS0NlYh|ryP NUHyflN6W0GQR1XS
BPH-1 MmrhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2j6dGlEPTB;Mj62OVg2KM7:TR?= NWjDR4JbW0GQR1XS
M14 Mmn1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXwSZR[UUN3ME2yMlY3QTl|IN88US=> MXTTRW5ITVJ?
G-402 MoLOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVO3UXFtUUN3ME2yMlcxPDVzIN88US=> NYT6PIdbW0GQR1XS
AsPC-1 NV\OU|RpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHq0bJhKSzVyPUKuO|EyPyEQvF2= M{C4VXNCVkeHUh?=
NB12 NHrLR3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLxbnVKSzVyPUKuO|E4OSEQvF2= M{\mR3NCVkeHUh?=
SK-HEP-1 Ml\pS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTJwN{SzPVEh|ryP MYnTRW5ITVJ?
U-266 MmLzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlXoTWM2OD1{Lke3NVIyKM7:TR?= MUHTRW5ITVJ?
AM-38 MmXhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFfxVWxKSzVyPUKuO|c{PTVizszN MYrTRW5ITVJ?
PC-14 M1SzO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTJwOEC1NUDPxE1? NF\5N5ZUSU6JRWK=
EGI-1 M4S0PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{T0[2lEPTB;Mj64NVc1OyEQvF2= NFHyTopUSU6JRWK=
LS-411N MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmD5TWM2OD1{LkiyN|Mh|ryP NXnESXVWW0GQR1XS
BFTC-905 M3LK[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoXqTWM2OD1{Lki1OVI{KM7:TR?= Mmq0V2FPT0WU
CaR-1 NV7L[Hp4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIPlV5dKSzVyPUKuPFYh|ryP NEGzT5RUSU6JRWK=
NCI-H292 MmizS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmHZTWM2OD1{Lki2OVk3KM7:TR?= NYOzc3pJW0GQR1XS
8305C MlP5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XLT2lEPTB;Mj64OlY1PSEQvF2= NF24bYFUSU6JRWK=
SNU-449 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTJwOEmxPFIh|ryP MWXTRW5ITVJ?
LCLC-103H M{XqZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3vKRmlEPTB;Mj65NFQ{QCEQvF2= NG\0VlZUSU6JRWK=
SW1573 M3;tSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWWxdVhFUUN3ME2yMlk3ODh{IN88US=> MYrTRW5ITVJ?
MLMA NVrkVpNnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITjXlhKSzVyPUKuPVY4OTdizszN NV;j[3lXW0GQR1XS
NCI-H1355 NHjpb21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2rncWlEPTB;Mz6wNFc6PiEQvF2= MoPEV2FPT0WU
RMG-I M4LXVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4\WbWlEPTB;Mz6wNlU6OiEQvF2= NGm2dYRUSU6JRWK=
BB65-RCC NE\nbmdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;NfoR6UUN3ME2zMlA{OzF2IN88US=> NIfx[3FUSU6JRWK=
PC-3 NYTEUo9PT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEnOflRKSzVyPUOuNFM5PzRizszN NFjId2hUSU6JRWK=
SF268 NUKzfFhDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\EdXV7UUN3ME2zMlA1PTJ|IN88US=> MWDTRW5ITVJ?
NCI-H810 M3;mdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXLlfWRMUUN3ME2zMlA1QDJ|IN88US=> NVj2WI9TW0GQR1XS
MEG-01 M3\aTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M33O[WlEPTB;Mz6wOlE3PCEQvF2= NHzIVnNUSU6JRWK=
SW13 NGewS2dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH:xVmlKSzVyPUOuNFc5PDdizszN NUTFdXFFW0GQR1XS
RH-1 M1zIPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV\JR|UxRTNwMUCyO|gh|ryP NFH0UFVUSU6JRWK=
GT3TKB NXrvZppNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4XQWWlEPTB;Mz6xNVI5OyEQvF2= MnrNV2FPT0WU
TK10 M{TtZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXBTWM2OD1|LkGzO|I1KM7:TR?= NGfKdYVUSU6JRWK=
T-24 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;1TmlEPTB;Mz6xOVA4KM7:TR?= MmHCV2FPT0WU
A498 MnP6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnzbFdKSzVyPUOuNlA5PzFizszN NYTEV286W0GQR1XS
GR-ST NXHoPHhJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4rqS2lEPTB;Mz6yNlE{QSEQvF2= NGO3PJJUSU6JRWK=
LB2518-MEL NH;2NWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfBUIZ7UUN3ME2zMlIzOzl6IN88US=> NIDrRWxUSU6JRWK=
T47D MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHXNZYxKSzVyPUOuNlM3OjdizszN M3LtO3NCVkeHUh?=
NCI-H1651 NWXpWZQ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTNwMkS2OFQh|ryP NGG0bZVUSU6JRWK=
EC-GI-10 M{nTfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\I[nlKSzVyPUOuNlYyPTNizszN M4jaTHNCVkeHUh?=
HT-29 MkHqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\VXYRKSzVyPUOuNlY3OTRizszN MXLTRW5ITVJ?
GI-ME-N MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1KyemlEPTB;Mz6yPVUyOSEQvF2= MUjTRW5ITVJ?
SW756 NVr6UmVyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmO0TWM2OD1|LkK5OlI6KM7:TR?= MkLRV2FPT0WU
RKO M1X3RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NG\l[5RKSzVyPUOuN|A4PTdizszN MXPTRW5ITVJ?
NCI-H1563 MmTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYfJR|UxRTNwM{OwNVgh|ryP Mm\GV2FPT0WU
DJM-1 NEXHfJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVXrOVZVUUN3ME2zMlM4Pjd2IN88US=> M1myUHNCVkeHUh?=
L-428 NVHyW5I1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTNwNECwOFUh|ryP Moe0V2FPT0WU
NCI-H2122 NYjF[HNKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHTqUXVKSzVyPUOuOFE{OTJizszN NVnx[GJGW0GQR1XS
Ca-Ski NFO4TYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHyPVRKSzVyPUOuOFU1OyEQvF2= MX\TRW5ITVJ?
639-V MljhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTNwNE[wOVch|ryP NWTtPW9XW0GQR1XS
SW1116 NXTaOZhqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmCyTWM2OD1|LkS2NlY6KM7:TR?= M{j0Z3NCVkeHUh?=
DMS-114 MkXMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlrVTWM2OD1|LkS3NFY3KM7:TR?= MYDTRW5ITVJ?
MZ2-MEL MlHTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTmTWM2OD1|LkS3OlgyKM7:TR?= NE\EfGFUSU6JRWK=
COLO-829 M2rLO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWf1VlRCUUN3ME2zMlUxODd|IN88US=> NVrCcphKW0GQR1XS
J82 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEPmbpdKSzVyPUOuOVA2PyEQvF2= MXfTRW5ITVJ?
EW-13 NEPHe5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXOOm5{UUN3ME2zMlUzPTFizszN M{PwS3NCVkeHUh?=
RXF393 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHhTWM2OD1|LkWzNlk1KM7:TR?= M{fORXNCVkeHUh?=
CAL-62 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlW0TWM2OD1|LkW0OVE1KM7:TR?= NHnqVnRUSU6JRWK=
OCUB-M M2rLeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHju[2lKSzVyPUOuOVQ3PjVizszN M4PDO3NCVkeHUh?=
BT-474 NHvvZ|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTNwNkOzNUDPxE1? MkPWV2FPT0WU
KYSE-180 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{i0VmlEPTB;Mz62N|M4OiEQvF2= M2m4VHNCVkeHUh?=
NCI-H650 NVPNSpZRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH:4XHZKSzVyPUOuOlQzQDdizszN MXnTRW5ITVJ?
Detroit562 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTMOG9rUUN3ME2zMlY2ODJ{IN88US=> MXXTRW5ITVJ?
SW48 NF7LWGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVPJR|UxRTNwNkW2OVch|ryP M4jId3NCVkeHUh?=
KYSE-450 NIfWVZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHEUJNKSzVyPUOuOlg2QDJizszN NHH6eZdUSU6JRWK=
KYSE-510 NY\xXJNxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTNwN{KxPFEh|ryP NE\ycm1USU6JRWK=
GP5d MoTKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWrJR|UxRTNwN{K5OUDPxE1? NFz0cmxUSU6JRWK=
RPMI-7951 NYjRNWpQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;OTWM2OD1|Lke0O|I{KM7:TR?= M3nUO3NCVkeHUh?=
Becker NVHJXpFZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoXFTWM2OD1|Lke1NFEzKM7:TR?= Mm\XV2FPT0WU
WM-115 Mn;1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH7sOZpKSzVyPUOuO|gyQTVizszN MlTCV2FPT0WU
G-401 NHzpZXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUnCZpNsUUN3ME2zMlc6ODh3IN88US=> NHL0XWxUSU6JRWK=
PANC-08-13 MlO2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfhRlJtUUN3ME2zMlc6PjB{IN88US=> MWnTRW5ITVJ?
SW982 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYDFT|F2UUN3ME2zMlgxPTVzIN88US=> MoDKV2FPT0WU
D-263MG NFHiRWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFnUUFhKSzVyPUOuPFIxPTFizszN MULTRW5ITVJ?
KM-H2 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHvld3lKSzVyPUOuPFI3OjRizszN M{e1eXNCVkeHUh?=
SK-MEL-3 NIP1fmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnXXTWM2OD1|LkiyPFQyKM7:TR?= M3jRPHNCVkeHUh?=
NCI-H1581 NI\1bFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XDdWlEPTB;Mz64OFQ5QCEQvF2= NFnu[XdUSU6JRWK=
LS-123 MkPXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TyXGlEPTB;Mz64O|kxQSEQvF2= MorzV2FPT0WU
CAKI-1 NGXEOIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLhdWJ1UUN3ME2zMlg6ODV{IN88US=> NGXsOWlUSU6JRWK=
MEL-JUSO MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mln2TWM2OD1|Lki5NVU{KM7:TR?= MlLRV2FPT0WU
HCE-4 Mn3lS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTNwOUG2OlMh|ryP NGmzcolUSU6JRWK=
TE-10 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2HzWGlEPTB;Mz65NlAyKM7:TR?= M1HKXXNCVkeHUh?=
OVCAR-4 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{n1cmlEPTB;Mz65Nlg5QSEQvF2= Moj5V2FPT0WU
ETK-1 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvnTWM2OD1|Lkm0OlM2KM7:TR?= NVGzV5pSW0GQR1XS
A2780 MnjJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XYTGlEPTB;ND6wOVk3PiEQvF2= NVnYdpgxW0GQR1XS
LU-65 Mnv0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXnEbnZuUUN3ME20MlA4PjN|IN88US=> NFT5dVJUSU6JRWK=
BHY MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2T2SGlEPTB;ND6xNlQ6PSEQvF2= NWWwc4dCW0GQR1XS
COR-L105 NF;mTIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTRwMUOwOVEh|ryP NV\qVWpvW0GQR1XS
CAL-12T M2rYNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXnmTGhXUUN3ME20MlE{OTB|IN88US=> M1HQWXNCVkeHUh?=
SCH Ml7oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXW5dWJSUUN3ME20MlE2PzR|IN88US=> M{XaTXNCVkeHUh?=
CW-2 NIHZcIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXjJR|UxRTRwMUmwNFEh|ryP NWPoVZd4W0GQR1XS
HCC1806 M{LFWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\DTWM2OD12LkKwN|EzKM7:TR?= NFyzdZhUSU6JRWK=
KP-N-YN MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXi1PWVSUUN3ME20MlIxQTJ5IN88US=> MkXWV2FPT0WU
T98G MmPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYPI[pRXUUN3ME20MlIzOTV5IN88US=> MkLrV2FPT0WU
CAL-54 MmXDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVf6O4NlUUN3ME20MlIzOzhzIN88US=> NFjTfHNUSU6JRWK=
CAL-33 MoW1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2LYUGlEPTB;ND6yN|A3PCEQvF2= MVrTRW5ITVJ?
SNU-C2B MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX\NTIxOUUN3ME20MlI1PzZ7IN88US=> M1zkXHNCVkeHUh?=
NUGC-3 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIDveHhKSzVyPUSuNlU2ODVizszN NFSyPVlUSU6JRWK=
DOK MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfJR|UxRTRwMk[1PVMh|ryP MVnTRW5ITVJ?
MMAC-SF MnvwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHjYb5FKSzVyPUSuNlY5PTlizszN NELY[|VUSU6JRWK=
KYSE-70 NHH0S2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvXTWM2OD12LkK5N|Qh|ryP NWLtW5FGW0GQR1XS
A204 MkDnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXnW[nJUUUN3ME20MlM2QDB|IN88US=> NH3JUlFUSU6JRWK=
SCC-25 NF\0eJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4LCUWlEPTB;ND6zOVgyQSEQvF2= MWHTRW5ITVJ?
EPLC-272H NEDJWWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV\mUHlSUUN3ME20MlM5QTVizszN MWXTRW5ITVJ?
CAL-120 NEHubYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\Y[GZKSzVyPUSuN|g6QTJizszN MmHRV2FPT0WU
LS-513 NHi2PFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLidXVKSzVyPUSuOFIyQThizszN NUPGeGN3W0GQR1XS
CAPAN-1 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3TEN2lEPTB;ND60NlM5OiEQvF2= MlTSV2FPT0WU
ESS-1 NFrabIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2fzd2lEPTB;ND60NlczPCEQvF2= MnKwV2FPT0WU
GMS-10 NUTWUnRTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPUS2lTUUN3ME20MlQzQDF7IN88US=> MknVV2FPT0WU
NCI-N87 M33SXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn3xTWM2OD12LkWwPFY5KM7:TR?= Mlm0V2FPT0WU
HMV-II M3SzOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;CTWM2OD12LkWxO|Mh|ryP Mlj4V2FPT0WU
COLO-741 NW\XWZFDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHnVWJdKSzVyPUSuOVU6QTRizszN MWLTRW5ITVJ?
MKN45 Mnq3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTRwNUe3N|Ih|ryP NUPW[nZ4W0GQR1XS
OAW-28 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYqzcHJZUUN3ME20MlU5Ozl6IN88US=> NUDvXWoxW0GQR1XS
OCI-AML2 M3zPPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjaNHFKSzVyPUSuOlUzOzhizszN Mn\6V2FPT0WU
MDA-MB-231 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3fGO2lEPTB;ND63NFI1OyEQvF2= NVHBO2ZOW0GQR1XS
NCI-H1648 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{HNfWlEPTB;ND63NlI4OyEQvF2= NIHETYNUSU6JRWK=
NCI-H1792 NE\JcGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjFdYhKSzVyPUSuO|YyODdizszN M1PxTXNCVkeHUh?=
GCIY M1PiRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfkd3hKSzVyPUSuO|c1OjRizszN MXfTRW5ITVJ?
Hs-578-T MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3;5cGlEPTB;ND63O|Y2PSEQvF2= M2juXHNCVkeHUh?=
SW962 MnrVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3PwNGlEPTB;ND63PFAyOSEQvF2= NGLqbZRUSU6JRWK=
NCI-H630 NYTOSZlRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTRwN{iwPFEh|ryP MmLsV2FPT0WU
786-0 NX:zVJY6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1LrTGlEPTB;ND63PFc4OyEQvF2= MoDGV2FPT0WU
FTC-133 M3vwUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXLJR|UxRTRwN{myOlMh|ryP MXLTRW5ITVJ?
BT-20 M{n1bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIHjT4NKSzVyPUSuO|k1OjlizszN MXPTRW5ITVJ?
Mewo M{TRWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTRwOEG3OFch|ryP MmLuV2FPT0WU
SW780 Ml;aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MknyTWM2OD12Lki1O|Y3KM7:TR?= MWDTRW5ITVJ?
OE33 NF;PR25Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NETHWJlKSzVyPUSuPFc4OTNizszN NE\4c3JUSU6JRWK=
HCC1569 MlPmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXFTWM2OD12Lki4OFU5KM7:TR?= NVi1bVluW0GQR1XS
TE-6 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoDiTWM2OD12LkmzPVc4KM7:TR?= NIHaV45USU6JRWK=
SK-N-FI MnnQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTRwOUS0NlEh|ryP NWHFV5pXW0GQR1XS
PANC-03-27 M2HHUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYjTWph4UUN3ME20Mlk6QTZ{IN88US=> NFPONlJUSU6JRWK=
MCF7 Ml;5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV3JR|UxRTVwMEC3N|gh|ryP M3LlNHNCVkeHUh?=
UACC-257 M3G0Tmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnMeIhlUUN3ME21MlAzQDR3IN88US=> NF[4bIpUSU6JRWK=
SW1088 NHG2T|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTVwMEK5OFQh|ryP M{\sc3NCVkeHUh?=
A704 MkLiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFLRflNKSzVyPUWuNFMxPiEQvF2= NHzMRpFUSU6JRWK=
A2058 M2XFemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILPN5ZKSzVyPUWuNFU6ODhizszN Mmn3V2FPT0WU
Calu-3 NH[2NVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmDSTWM2OD13LkC2OFUzKM7:TR?= NXv5cnR[W0GQR1XS
RERF-LC-MS M1\qcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTVwME[5NFMh|ryP Mn60V2FPT0WU
AU565 NWjoT4xKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWnJR|UxRTVwMEm3NFIh|ryP M{G0UXNCVkeHUh?=
DMS-79 NHzGSIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnDVm1KSzVyPUWuNVM5QDNizszN MoS2V2FPT0WU
DK-MG NE\5N|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTVwMUi0N|gh|ryP NID0SFBUSU6JRWK=
HuCCT1 NHX3OIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{K5VGlEPTB;NT6yN|g2PiEQvF2= M4rMeHNCVkeHUh?=
HT-144 M1qxcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Moi5TWM2OD13LkK0PVg4KM7:TR?= M4jPO3NCVkeHUh?=
M059J MlW4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGX1bWJKSzVyPUWuNlU4PiEQvF2= NE\OSHdUSU6JRWK=
COLO-792 MlPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7OTWM2OD13LkK2N|U3KM7:TR?= M4PXVnNCVkeHUh?=
SF539 NXvoOmlIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGDyOWpKSzVyPUWuNlY3OzJizszN NX[z[215W0GQR1XS
SK-UT-1 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTVwMke3OVEh|ryP NIHkXolUSU6JRWK=
NCI-H1703 MkfMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3z5SGlEPTB;NT6zOVgzPiEQvF2= Mmn3V2FPT0WU
SW837 NX7FcVdOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTVwM{e4O|gh|ryP M4\SZnNCVkeHUh?=
U251 MmDHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWPJR|UxRTVwM{mwPVYh|ryP M{mzVXNCVkeHUh?=
SW1710 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7NTWM2OD13LkSxOVU1KM7:TR?= Mkn1V2FPT0WU
NCI-H1299 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4K2dmlEPTB;NT60OlM{PSEQvF2= M{DBbHNCVkeHUh?=
RVH-421 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NY\EZXF[UUN3ME21MlQ6QTB6IN88US=> M2G4d3NCVkeHUh?=
UM-UC-3 M1uwNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWPJR|UxRTVwNkK2OVEh|ryP NXPUbWd[W0GQR1XS
MDA-MB-175-VII NIi0RolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVHW[3ExUUN3ME21MlY1ODRzIN88US=> NHfWOHJUSU6JRWK=
KYSE-270 MoPrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\WfHIzUUN3ME21MlY3ODNzIN88US=> MVrTRW5ITVJ?
COLO-668 NH[5VYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3TR[WlEPTB;NT63NVMzKM7:TR?= MlWwV2FPT0WU
LN-405 NGezbGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTVwN{OwPFUh|ryP Ml;zV2FPT0WU
HT-1376 NYXUU5RsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTVwN{iwOVIh|ryP NITke3NUSU6JRWK=
769-P NFrjXYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M37N[2lEPTB;NT64OlcyQCEQvF2= NVW0UZVSW0GQR1XS
HuP-T3 NFrNVHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmGwTWM2OD13Lki4Olc4KM7:TR?= NGL2eWdUSU6JRWK=
MDA-MB-415 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFHveI1KSzVyPUWuPVIyOzlizszN Ml6zV2FPT0WU
MKN7 NHHZbIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M37obGlEPTB;NT65PFgh|ryP NG\EUXNUSU6JRWK=
KS-1 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF35b5BKSzVyPUWuPVg5OzZizszN NEjuZWRUSU6JRWK=
647-V M{O3eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGPrZolKSzVyPUWuPVkyPDhizszN M3PXeXNCVkeHUh?=
COLO-679 NVHHV2JwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPyblhZUUN3ME22MlAxOjV3IN88US=> NG\PRoxUSU6JRWK=
AN3-CA NESxb3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzJS4F2UUN3ME22MlA{PDRzIN88US=> NFyyelNUSU6JRWK=
C32 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1L3RmlEPTB;Nj6xN|A{PCEQvF2= MXTTRW5ITVJ?
KM12 MmfzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIfsR3hKSzVyPU[uNlQxQTlizszN NWnBbmYxW0GQR1XS
KINGS-1 NWCwU|BpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWLsVG5TUUN3ME22MlI3OTV{IN88US=> NGrRd|NUSU6JRWK=
KYSE-410 NYW0SYpmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoXRTWM2OD14LkOwOlQ2KM7:TR?= MVjTRW5ITVJ?
HPAF-II NIizRmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGTRWZBKSzVyPU[uN|U1QCEQvF2= MljNV2FPT0WU
LAN-6 NYjydZpPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2K3VmlEPTB;Nj60PVY{OSEQvF2= M3fyPXNCVkeHUh?=
LU-99A NFHDVWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NULjZow{UUN3ME22MlU2QTh7IN88US=> MX;TRW5ITVJ?
SJSA-1 NFzFWWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlGyTWM2OD14LkW2N|Q4KM7:TR?= NEHuNmFUSU6JRWK=
MSTO-211H MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3zhcWlEPTB;Nj63NlI{OyEQvF2= NFG3U3FUSU6JRWK=
SW900 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWrJR|UxRTZwN{[yNlEh|ryP NIO0PYtUSU6JRWK=
LNCaP-Clone-FGC NVmwdoEyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGLMWIpKSzVyPU[uPFA1ODNizszN NUfMNoRHW0GQR1XS
OMC-1 NF7BRnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\nSGlEPTB;Nj64OVQxOiEQvF2= NXLuUWxkW0GQR1XS
IST-MEL1 Mof1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXPJR|UxRTZwOEm2Olkh|ryP MYPTRW5ITVJ?
TE-9 MknYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHQOVJOUUN3ME22Mlg6QDR5IN88US=> NFjjZY1USU6JRWK=
NCI-H2030 NEnSUWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWfX[3VCUUN3ME22MlkyOjJ4IN88US=> NYPlV2t6W0GQR1XS
BFTC-909 MlmzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYLpU4tpUUN3ME23MlAxPjRzIN88US=> NYHiPGRPW0GQR1XS
NCI-SNU-5 NX3XTWE3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTdwMEKxOVkh|ryP NIPITndUSU6JRWK=
TE-5 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPkPJFSUUN3ME23MlAzQDhzIN88US=> MVnTRW5ITVJ?
SK-MES-1 NVnkUYE1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzpUmZKSzVyPUeuNFU1OjdizszN MoP2V2FPT0WU
SHP-77 NHnReGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1jqSmlEPTB;Nz6xN|k2OiEQvF2= M3HkW3NCVkeHUh?=
NCI-H1623 M2rJPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3PXTGlEPTB;Nz6xOFA4OiEQvF2= NGO3WZFUSU6JRWK=
TE-11 Mme2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrHU|JKSzVyPUeuNVUyQDRizszN MUnTRW5ITVJ?
EKVX NFLhdnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGGxS2lKSzVyPUeuNVkzPjdizszN NGTQXWNUSU6JRWK=
OVCAR-3 NYL1Tmo6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU[4foVCUUN3ME23MlIyOTN|IN88US=> NU[yR4FCW0GQR1XS
C3A NWH3[G94T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGjXbo5KSzVyPUeuN|Q2OiEQvF2= MYDTRW5ITVJ?
CFPAC-1 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlj5TWM2OD15LkO2NlIzKM7:TR?= NGHP[5VUSU6JRWK=
MG-63 NXnJV|cyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1W2fWlEPTB;Nz60NVg1QSEQvF2= MmLFV2FPT0WU
KYSE-140 MojmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTdwNESwOlEh|ryP MoDSV2FPT0WU
MPP-89 M1TJ[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3;YWmlEPTB;Nz61PVczQSEQvF2= MluzV2FPT0WU
COLO-824 NFrQcXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnXYTWM2OD15LkeyPFY{KM7:TR?= NEnlZZRUSU6JRWK=
SiHa NHrJflBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XSNWlEPTB;Nz64N|cxPyEQvF2= MWjTRW5ITVJ?
SNU-387 M1;SUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnnpTWM2OD15Lki1N|Q4KM7:TR?= NV\iWmg5W0GQR1XS
A172 NGr1SZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHab|ZKSzVyPUeuPFYyPzJizszN NIT6[nJUSU6JRWK=
COLO-680N NYnwOFF2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\nSmlEPTB;Nz65NVc{KM7:TR?= NWfXclJpW0GQR1XS
HCC1395 MorUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\nSGlEPTB;OD6wOVQ2OiEQvF2= MXzTRW5ITVJ?
NCI-H28 NVnxeW4xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1riVGlEPTB;OD6wOVk3OyEQvF2= M1Pk[XNCVkeHUh?=
LC-2-ad NHv2fXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4L3RmlEPTB;OD6yNVk{PyEQvF2= NXPpR4l7W0GQR1XS
S-117 MkXVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\PS2lEPTB;OD6yOVM2OyEQvF2= MVfTRW5ITVJ?
NCI-H1838 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\4TWM2OD16LkK1O|gyKM7:TR?= MUHTRW5ITVJ?
PANC-10-05 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\nXIpyUUN3ME24MlM4ODR5IN88US=> M1HnWnNCVkeHUh?=
KALS-1 NYTlTos4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRThwNUC5Nlgh|ryP MofpV2FPT0WU
LS-1034 M4jCXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXnJR|UxRThwNUe0N|ch|ryP MoXHV2FPT0WU
TGBC1TKB M130dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDFXZVWUUN3ME24Mlc{PTN3IN88US=> MXLTRW5ITVJ?
OE19 MmHXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoniTWM2OD16Lke2NlYzKM7:TR?= M1;Z[3NCVkeHUh?=
D-502MG NV3mfY9oT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYLJR|UxRThwN{[5PVQh|ryP M2HkXXNCVkeHUh?=
JEG-3 M2nCZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWDJR|UxRThwN{i2NVgh|ryP NV;NbINiW0GQR1XS
DBTRG-05MG M{fqR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHjaZphKSzVyPUiuPFc2PjVizszN NUj2Xog1W0GQR1XS
ME-180 MlfUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVfJR|UxRTlwME[3NlUh|ryP NXHkNYFKW0GQR1XS
NCI-H1573 NYHQd5VDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfp[YNTUUN3ME25MlExPTN{IN88US=> NX:1TGhPW0GQR1XS
HCC2998 NVvXWXFvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mo[xTWM2OD17LkGzOlgyKM7:TR?= MX;TRW5ITVJ?
ACHN MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3;YSWlEPTB;OT6yOFk4PSEQvF2= M1exNnNCVkeHUh?=
D-392MG MkfaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvERmt3UUN3ME25MlI2PzF3IN88US=> NXnK[5U4W0GQR1XS
no-11 Mli1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUXJR|UxRTlwMk[wNlgh|ryP MWHTRW5ITVJ?
KLE NIjZPZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M130UWlEPTB;OT6zNlI{OiEQvF2= M{DFTnNCVkeHUh?=
Calu-6 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXtTWM2OD17LkO3OVI5KM7:TR?= NWjO[2d2W0GQR1XS
LB831-BLC NIjtTJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUfaOmZyUUN3ME25MlQ2OTdzIN88US=> NHO0R|NUSU6JRWK=
SW684 M4XrfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXN[INKSzVyPUmuOFYyOTZizszN MWTTRW5ITVJ?
SH-4 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PG[mlEPTB;OT60PVM3PCEQvF2= NFXWNYZUSU6JRWK=
IST-MES1 NGj4UFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHy0NpRKSzVyPUmuOVE3PDRizszN NUfhcoFpW0GQR1XS
Saos-2 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4n3RmlEPTB;OT61NlE6PSEQvF2= MY\TRW5ITVJ?
NCI-H2087 Ml31S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MknrTWM2OD17Lk[3N|UzKM7:TR?= NIXGZWpUSU6JRWK=
SCC-9 M3vkS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TYNGlEPTB;OT63NVgyPiEQvF2= MWfTRW5ITVJ?
MFE-280 M2L6O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3q1WWlEPTB;OT63Nlc5PSEQvF2= MlzBV2FPT0WU
BEN MnLrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY\JR|UxRTlwOEKxOVkh|ryP MkK2V2FPT0WU
CP50-MEL-B NH\x[HRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjnSndTUUN3ME25MlkzPDN{IN88US=> MV7TRW5ITVJ?
SK-MEL-28 M1jGd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3HsfGlEPTB;MUCuNFE6OyEQvF2= M3;TSnNCVkeHUh?=
NCI-H2452 NXHDZ4w4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnRTWM2OD1zMD6xOkDPxE1? NFfYSoxUSU6JRWK=
NCI-H1395 NVrQcWR3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MonhTWM2OD1zMD6xO|gh|ryP MlrNV2FPT0WU
NCI-H2052 M2[zcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYXCU4s2UUN3ME2xNE4yQDh{IN88US=> NUTocGh4W0GQR1XS
A375 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHuyV4VKSzVyPUGwMlI1PTJizszN MWPTRW5ITVJ?
HCC38 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLVTWM2OD1zMD6zNlIh|ryP NGLJSllUSU6JRWK=
LK-2 M1O3bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXnvPVRSUUN3ME2xNE41OjB6IN88US=> NF;VPVRUSU6JRWK=
SF126 NIDTeZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;ONVF6UUN3ME2xNE41PzJ5IN88US=> MYHTRW5ITVJ?
SK-MEL-1 M2jKTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYDJR|UxRTFyLke4N|gh|ryP M4nQ[HNCVkeHUh?=
ACN M33KNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHr1[XBKSzVyPUGwMlg3PzlizszN M1PNNnNCVkeHUh?=
BB30-HNC NX\pUm5DT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXPJR|UxRTFyLki3NVEh|ryP M1rGT3NCVkeHUh?=
NCI-H747 Mle3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRTFyLki3OFYh|ryP MVPTRW5ITVJ?
KYSE-150 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnZd4FEUUN3ME2xNU4xOzh5IN88US=> MWPTRW5ITVJ?
D-247MG NU\vb4xST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3i3XmlEPTB;MUGuNVAxQSEQvF2= MlzVV2FPT0WU
BxPC-3 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1TNOWlEPTB;MUGuN|c1PyEQvF2= NV;QO2hlW0GQR1XS
SK-MEL-30 NFT1RW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkC3TWM2OD1zMT60NFc6KM7:TR?= NVTCd5N7W0GQR1XS
CAS-1 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M13wdmlEPTB;MUGuOFExQSEQvF2= MkXNV2FPT0WU
no-10 NEPXc2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYDJR|UxRTF{LkGyNVch|ryP MlTsV2FPT0WU
NCI-H2405 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvnTWM2OD1zMj6yNFM3KM7:TR?= M3HoXnNCVkeHUh?=
KGN MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXHJR|UxRTF{LkK5NFEh|ryP Mkf0V2FPT0WU
BB49-HNC Mn7ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1q2RWlEPTB;MUKuN|k2PiEQvF2= NVPn[pNPW0GQR1XS
NCI-H1693 NXvKVnN6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXrJR|UxRTF{LkW4NVYh|ryP MV7TRW5ITVJ?
RO82-W-1 M2D5emdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTF|LkC2OFkh|ryP MXTTRW5ITVJ?
CAL-85-1 M{LkXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXzJR|UxRTF|LkSzPVkh|ryP M1vkVHNCVkeHUh?=
H-EMC-SS MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2q3U2lEPTB;MUOuPVExPCEQvF2= MXTTRW5ITVJ?
SW1783 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfkOYtKSzVyPUG0MlI{QTFizszN NVHrbphpW0GQR1XS
LB771-HNC NXW2VnRGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTF2LkSxPUDPxE1? M1\vSXNCVkeHUh?=
HCC70 NIHFOWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXPINoc2UUN3ME2xOE41OjN|IN88US=> MVrTRW5ITVJ?
KNS-81-FD NULvXJlUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIf0[I9KSzVyPUG0MlcxPDVizszN M{jtSHNCVkeHUh?=
KYSE-520 NV63OHc{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV[0Z|N5UUN3ME2xOE46OjdizszN MUHTRW5ITVJ?
TGBC24TKB M3[zXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTF2Lkm1N|kh|ryP MXjTRW5ITVJ?
SNB75 Mn;sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTF3LkC3Nlkh|ryP NVHIZVZQW0GQR1XS
SW872 NH\JcHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2TxTmlEPTB;MUWuNlIyQCEQvF2= M3\6OHNCVkeHUh?=
U031 NXWy[|lET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NETicopKSzVyPUG1MlgxOjhizszN M4X3Z3NCVkeHUh?=
ChaGo-K-1 M{\GdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2rWVWlEPTB;MUWuPFM2QSEQvF2= MYfTRW5ITVJ?
NCI-H441 M1rnN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmDBTWM2OD1zNj6wNFM6KM7:TR?= MXTTRW5ITVJ?
TE-12 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnqPYdKSzVyPUG2MlE5PzNizszN NVrt[IpqW0GQR1XS
NCI-H1755 NY\qbIo4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFr5eIZKSzVyPUG2MlU4OyEQvF2= MVfTRW5ITVJ?
KNS-42 MnG1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTNdYVMUUN3ME2xOk43PTh7IN88US=> Mnz3V2FPT0WU
SK-PN-DW M4fiXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX\JR|UxRTF5LkSyNFEh|ryP MlPlV2FPT0WU
NCI-H226 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jWS2lEPTB;MUeuPVM1PSEQvF2= MYLTRW5ITVJ?
K-562 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfSb|d1UUN3ME2xPE43OzF5IN88US=> MVPTRW5ITVJ?
A388 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkO1TWM2OD1zOT6wN|A{KM7:TR?= MlTHV2FPT0WU
ZR-75-30 NUHZNotrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV3JRnlsUUN3ME2xPU4xQTZ6IN88US=> NIDhOGNUSU6JRWK=
LU-135 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFO5XWFKSzVyPUG5MlI3OzZizszN MofwV2FPT0WU
NCI-H2029 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoDoTWM2OD1zOT62NFIyKM7:TR?= MWnTRW5ITVJ?
HT-1197 NF21WXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIKzVnlKSzVyPUG5MlkzOjdizszN M13QRnNCVkeHUh?=
IGR-1 M2eyR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\vSGZbUUN3ME2yNE4{OTF5IN88US=> M3O0ZXNCVkeHUh?=
U-87-MG MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3PXFA1UUN3ME2yNE43PDF|IN88US=> M4LTO3NCVkeHUh?=
NCI-H1304 NUL0NlN4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHyT4piUUN3ME2yNE44PTBzIN88US=> MnHIV2FPT0WU
RCC10RGB NFTtVXdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIj3NlFKSzVyPUKxMlI5OjlizszN MXHTRW5ITVJ?
NCI-H520 M{nibmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTJ{Lke2NVEh|ryP NUf1ZXVmW0GQR1XS
SK-LU-1 M1mydGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYDJR|UxRTJ|LkC3NVgh|ryP MkDSV2FPT0WU
UACC-893 NYPHOWwxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmHlTWM2OD1{Mz6xNFM5KM7:TR?= M2nx[3NCVkeHUh?=
NCI-H2347 MmGwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGfvT2tKSzVyPUKzMlI3PzRizszN MnzDV2FPT0WU
U-118-MG M2fQWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYnJR|UxRTJ|LkeyNVch|ryP NGDTTINUSU6JRWK=
NCI-H596 MkLnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;0TWM2OD1{Mz65NFU2KM7:TR?= MX7TRW5ITVJ?
MZ1-PC MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHzeoxlUUN3ME2yOE43PzV7IN88US=> MYHTRW5ITVJ?
SW1417 M4XqOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXpTWM2OD1{NT6yOFk5KM7:TR?= MWnTRW5ITVJ?
NCI-H82 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnINIk2UUN3ME2yOk41Ojh6IN88US=> NIPvOI9USU6JRWK=
COLO-678 M3OzSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoHUTWM2OD1{Nz60PVE6KM7:TR?= NVnIT4gxW0GQR1XS
KURAMOCHI NETvW3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mli2TWM2OD1{OD6xNlYh|ryP MoG2V2FPT0WU
NCI-H1650 NYewVnlHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MojPTWM2OD1|MD6xPVI1KM7:TR?= NUW4SWs1W0GQR1XS
HCC1954 NIizXJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlP4TWM2OD1|MT6zOlY3KM7:TR?= Mn;IV2FPT0WU
GAK M3PpbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWqz[Is5UUN3ME2zNk4zPjF4IN88US=> MljhV2FPT0WU
YAPC NXnRdJYyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlH6TWM2OD1|Mz63OlQ5KM7:TR?= MWTTRW5ITVJ?
NCI-H2228 MoHzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\iepFUUUN3ME2zOE4{PjB3IN88US=> MkfkV2FPT0WU
VMRC-RCZ MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmThTWM2OD1|Nj6zNFIzKM7:TR?= NGX0S3lUSU6JRWK=
NMC-G1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkDHTWM2OD1|Nz6wOVI6KM7:TR?= NYHjUJZPW0GQR1XS
D-336MG MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIjaWmNKSzVyPUSxMlg1PDJizszN NILu[JRUSU6JRWK=
UACC-62 NHLQTmlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{jpNGlEPTB;NEKuOVUxPSEQvF2= M33OcHNCVkeHUh?=
C-33-A MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTR3LkOyOVYh|ryP MkDiV2FPT0WU
HCC1937 NV\yW4VjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jmZ2lEPTB;NEeuNVk2QCEQvF2= MUfTRW5ITVJ?
HDLM-2 MojjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUfJR|UxRTR5LkKyPFch|ryP NF;ZRmFUSU6JRWK=
NCI-H727 M2[1PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TtU2lEPTB;NEeuNlQ2OSEQvF2= M1nIT3NCVkeHUh?=
NY NX7YbZdUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7rWlBPUUN3ME20PU4{QTB6IN88US=> MXvTRW5ITVJ?
NCI-H2291 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGL5d3pKSzVyPUS5Mlg{ODFizszN NHjmVYxUSU6JRWK=

多くの細胞株試験データを見る場合、クリックしてください

体内試験 Administration of Vorinostat (~100 mg/kg/day) significantly inhibits the growth of CWR22 human prostate xenografts in nude mice with tumor reductions of 78%, 97% and 97%, at doses of 25 mg/kg/day, 50 mg/kg/day and 100 mg/kg/day, respectively, compared with control. Vorinostat induces the accumulation of acetylated core histones and prostate-specific antigen mRNA expression in CWR22 cells, resulting in higher levels of serum prostate-specific antigen than predicted from tumor volume alone. [2] Oral administration of Vorinostat (0.67g/L) crosses the blood-brain barrier, increases histone acetylation in the brain, and dramatically improves the motor impairment in the R6/2 mice model of Huntington's disease. [5]

お薦めの試験操作(参考用のみ)

キナーゼ試験:

[1]

+ 展開

Immunoprecipitation-HDAC assays:

The lysate of Jurkat cells is incubated for 1 hour on ice and cleared by centrifugation at 12,000 g for 10 minutes at 4 °C. Supernatants are precleared with 30 μL of 50% protein G-Sepharose slurry for 1 hour at 4 °C. Beads are pelleted by centrifugation and supernatants are incubated for 1 hour at 4 °C with 10 μg of IgG fraction from anti-HDAC1 or HDAC3 polyclonal antisera (preincubated 2 hours at room temperature with either the homologous or heterologous immunizing peptide). Both antisera are raised in rabbits against the carboxylterminal peptide of HDAC1 and HDAC3 by using synthetic peptides coupled to keyhole limpet hemocyanin. 30 μL of 50% protein G-Sepharose slurry is added for 1 hour at 4 °C. Immune complexes are pelleted by centrifugation and washed three times with 1 mL of lysis buffer. Beads are resuspended in 200 μL of HDAC buffer (20 mM Tris-HCl, pH 8.0/150 mM NaCl/10% glycerol), and the HDAC assay is performed with an 3H-acetylated peptide corresponding to amino acids 1-24 of histone H4. Released [3H]acetic acid is quantified by scintillation counting. For inhibitions studies, the immunoprecipitated complexes are preincubated with the different concentrations of Vorinostat for 30 minutes at 4 °C.
細胞試験:

[2]

+ 展開
  • 細胞株: LNCaP, PC-3, and TSU-Pr1
  • 濃度: Dissolved in DMSO, final concentrations ~7.5 μM
  • 反応時間: 1, 2, 3 and 4 days
  • 実験の流れ:

    Cells are exposed to various concentrations of Vorinostat for 1, 2, 3 and 4 days. Cell viability is assessed by trypan blue dye exclusion.


    (参考用のみ)
動物試験:

[2]

+ 展開
  • 動物モデル: Male BALB/c nude (nu/nu) mice implanted with CWR22 tumor cells
  • 製剤: Dissolved in DMSO
  • 投薬量: ~100 mg/kg/day
  • 投与方法: Injection i.p.
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 52 mg/mL (196.74 mM)
Ethanol 3 mg/mL (11.35 mM)
Water Insoluble
体内 順序で溶剤を入れること:
2% DMSO+30% PEG 300+ddH2O
5mg/mL

* 溶解度検測はSelleck技術部門によって行いますので、文献より提供された溶解度と差異がある可能性がありますが、生産工芸と不同ロット(lot)で起きる正常な現象ですから、ご安心ください。

化学情報

分子量 264.3
化学式

C14H20N2O3

CAS No. 149647-78-9
保管
in solvent
別名 SAHA, MK0683, suberoylanilide hydroxamic acid

便利ツール

モル濃度計算器

モル濃度計算器

解決のために必要とされるマス、ボリュームまたは濃度を計算してください。

マス (g) = 濃度 (mol/L) x ボリューム (L) x 分子量 (g/mol)

モル濃度計算器方程式

  • マス
    濃度
    ボリューム
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備することを要求される希釈剤を計算してください. セレック希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 輸入 輸出 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

マス 濃度 ボリューム 分子量

臨床試験

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01059552 Active, not recruiting Locally Advanced Non-small Cell Lung Cancer Fox Chase Cancer Center|National Comprehensive Cancer Network December 6, 2009 Phase 1
NCT02108002 Enrolling by invitation Von Hippel-Lindau Disease National Institute of Neurological Disorders and Stroke (NINDS)|National Institutes of Health Clinical Center (CC) March 5, 2014 Phase 1
NCT03022565 Not yet recruiting Uveal Melanoma Nicolas Acquavella|University of Miami Sylvester Comprehensive Cancer Center|University of Miami April 2017 --
NCT02943642 Not yet recruiting Mycosis Fungoides Angimmune LLC|City of Hope National Medical Center|Columbia University|Dana-Farber Cancer Institute|Feinberg School of Medicine, Northwestern University|H. Lee Moffitt Cancer Center and Research Institute|Ohio State University Comprehensive Cancer Center|Rush University Medical Center|Scott and White Hospital & Clinic|Yale University|Stanford University|Thomas Jefferson University|University of Arkansas|University of Colorado Denver School of Medicine Barbara Davis Center|University of Texas Southwestern Medical Center|University of Washington|Vanderbilt University School of Medicine|Washington University School of Medicine January 2017 Phase 2
NCT02836548 Recruiting Melanoma|Skin Neoplasms The Netherlands Cancer Institute June 2016 Phase 1|Phase 2
NCT02589145 Recruiting Lymphoma M.D. Anderson Cancer Center|Celgene Corporation June 2016 Phase 1|Phase 2

技術サポート

ストックの作り方、阻害剤の保管する方法、細胞実験や動物実験に注意すべきな点を全部含めており、製品を取扱う時よくあった質問に対して取扱説明書でお答えいたします。

Handling Instructions

他の質問がある場合は、お気軽くお問合せください。

  • * 必須

よくある質問(FAQ)

  • 問題1:

    What’s the recommendation about reconstitution of the compound for in vivo animal study?

  • 回答:

    We recommend the following vehicle for S1047: 2% DMSO, 40% PEG 300, 5% Propylene glycol, 1% Tween 80 at 5 mg/mL.

HDAC信号経路図

HDAC Inhibitors with Unique Features

相関HDAC製品

Tags: Vorinostat (SAHA, MK0683)を買う | Vorinostat (SAHA, MK0683) ic50 | Vorinostat (SAHA, MK0683)供給者 | Vorinostat (SAHA, MK0683)を購入する | Vorinostat (SAHA, MK0683)費用 | Vorinostat (SAHA, MK0683)生産者 | オーダーVorinostat (SAHA, MK0683) | Vorinostat (SAHA, MK0683)化学構造 | Vorinostat (SAHA, MK0683)分子量 | Vorinostat (SAHA, MK0683)代理店
×
細胞株 試験類型 濃度 培養時間 溶剤類型 活性叙述 PMID