ASK

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S8289 NQDI-1 <1 mg/mL 21 mg/mL <1 mg/mL
S8292 Selonsertib (GS-4997) <1 mg/mL 36 mg/mL 24 mg/mL
S0067 GS-444217 <1 mg/mL 60 mg/mL ''''<1 mg/mL

ASK製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8289

NQDI-1

NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death.

S8292

Selonsertib (GS-4997)

Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

S0067

GS-444217

GS-444217 (ASK1-IN-1) is a potent, selective, orally available and ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with IC50 of 2.87 nM.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8289

NQDI-1

NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death.

S8292

Selonsertib (GS-4997)

Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

S0067

GS-444217

GS-444217 (ASK1-IN-1) is a potent, selective, orally available and ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with IC50 of 2.87 nM.

Tags: ASK inhibition | ASK cancer | ASK activation | ASK target | ASK tumor | ASK phosphorylation | ASK activity | ASK inhibitor drugs | ASK kinase assay | ASK inhibitor cancer | ASK inhibitor therapy | ASK signaling pathway | ASK inhibitor review