Factor Xa

シグナル伝達経路

研究分野

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S3002 Rivaroxaban <1 mg/mL 87 mg/mL <1 mg/mL
S1593 Apixaban <1 mg/mL 18 mg/mL <1 mg/mL
S7280 Edoxaban <1 mg/mL 100 mg/mL <1 mg/mL
S5708 Edoxaban tosylate Monohydrate <1 mg/mL 49 mg/mL <1 mg/mL
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S3002

Rivaroxaban

Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM).

S1593

Apixaban

Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.

S7280

Edoxaban

Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug.

S5708

Edoxaban tosylate Monohydrate

Edoxaban Tosylate is the tosylate salt form of edoxaban, an orally active inhibitor of factor Xa with anticoagulant activity.