阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S6658 ETC-206 (AUM 001,ETC-1907206) <1 mg/mL 82 mg/mL <1 mg/mL
S7421 CGP 57380 <1 mg/mL 48 mg/mL <1 mg/mL
S8275 eFT-508 (eFT508) <1 mg/mL 13 mg/mL <1 mg/mL

MNK製品

新MNK製品
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S6658

ETC-206 (AUM 001,ETC-1907206)

ETC-206 is an orally available highly selective small-molecule MNK 1/2 inhibitor with IC50s of 64 nM and 86 nM, respectively.

S7421

CGP 57380

CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.

S8275

eFT-508 (eFT508)

eFT-508 (eFT508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S6658

ETC-206 (AUM 001,ETC-1907206)

ETC-206 is an orally available highly selective small-molecule MNK 1/2 inhibitor with IC50s of 64 nM and 86 nM, respectively.

S7421

CGP 57380

CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.

S8275

eFT-508 (eFT508)

eFT-508 (eFT508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth.

Tags: MNK activty | MNK inhibitor | MNK inhibitor review