PIKfyve

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1219 YM201636 <1 mg/mL 35 mg/mL <1 mg/mL
S6414 Apilimod -1 mg/mL 84 mg/mL -1 mg/mL

PIKfyve製品

新PIKfyve製品
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1219

YM201636

YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α and insensitive to Fabl (yeast orthologue).

S6414

Apilimod

Apilimod is a cell permeable small molecule that specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay. It is also an inhibitor of IL-12/23 and shows no activity toward other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K isoforms.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1219

YM201636

YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α and insensitive to Fabl (yeast orthologue).

S6414

Apilimod

Apilimod is a cell permeable small molecule that specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay. It is also an inhibitor of IL-12/23 and shows no activity toward other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K isoforms.

Tags: PIKfyve Inhibitor | PIKfyve modulator | PIKfyve Review