TAK1

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S8868 NG25 <1 mg/mL 100 mg/mL '2 mg/mL
S3607 Sarsasapogenin <1 mg/mL <1 mg/mL 5 mg/mL
S8663 Takinib <1 mg/mL 64 mg/mL '''<1 mg/mL

TAK1製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8868

NG25

NG25 is a novel inhibitor of TAK1 with enzymatic IC50s of 149 and 21.7 nM for TAK1 and MAP4K2 respectively.

S3607

Sarsasapogenin

Sarsasapogenin (SAR) is a steroidal sapogenin. It can provoke the generation of reactive oxygen species and activate unfolded protein response (UPR) signaling pathways. SAR potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages.

S8663

Takinib

Takinib (EDHS-206) is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib induces apoptosis.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8868

NG25

NG25 is a novel inhibitor of TAK1 with enzymatic IC50s of 149 and 21.7 nM for TAK1 and MAP4K2 respectively.

S3607

Sarsasapogenin

Sarsasapogenin (SAR) is a steroidal sapogenin. It can provoke the generation of reactive oxygen species and activate unfolded protein response (UPR) signaling pathways. SAR potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages.

S8663

Takinib

Takinib (EDHS-206) is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib induces apoptosis.