AP-1

AP-1製品

All (10)
AP-1阻害剤 (2)
AP-1活性剤(1)
AP-1作動薬(2)
AP-1モジュレータ(1)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S9721	Farudodstat	Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase) with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosis transcriptional program in acute myeloid leukemia (AML) cells via activation of AP-1 transcription factors.	Front Cell Dev Biol, 2023, 11:1089945 iScience, 2022, 25(5):104293 bioRxiv, 2021, 10.1101/2021.06.28.450163
S9193	Aristolochic acid A	Aristolochic acid A (Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736) is a carcinogenic, mutagenic, and nephrotoxic agent extracted from the flowering plant family Aristolochiaceae.Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and nuclear factor-κB (NF-κB) activities.	Mol Ther Nucleic Acids, 2020, 6;19:1276-1289 Am J Physiol Renal Physiol, 2020, 319(6):F1003-F1014
S0855	TC-E 5003	TC-E 5003 (NSC 30176, Compound 2e) is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) with IC50 of 1.5 μM. TC-E 5003 modulates the lipopolysaccharide (LPS)-induced AP-1 and NF-κB signaling pathways and can possibly be further developed as an anti-inflammatory compound.	Biol Direct, 2025, 20(1):60 Hepatol Commun, 2025, 9(4)e0647 Mol Ther, 2023, 10.1016/j.ymthe.2023.09.011
F1623	pro NGF Antibody [J14K17]
S9490	Cobalt chloride	Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation. Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1α and AP-1 and iNOS signaling.Cobalt chloride can be used to induce animal models of High-altitude Polycythemia (HAPC).This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	Clin Transl Med, 2024, 14(2):e1567 J Transl Med, 2024, 22(1):245
F3379^New	Fos B Antibody [G14F16]
S0249	Mycro 3	Mycro 3 is a potent and selective inhibitor of c-Myc in whole cell assays. Mycro 3 also shows weak inhibitory activity against AP-1.	J Biol Chem, 2025, S0021-9258(25)00377-1
S7468^New	SR 11302	SR 11302は活性化蛋白質-1（AP-1）転写因子阻害剤です。SR 11302は、レチノイン酸応答エレメント（RARE）の転写を活性化することなく、AP-1活性を特異的に阻害するレチノイドです。
S9721	Farudodstat	Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase) with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosis transcriptional program in acute myeloid leukemia (AML) cells via activation of AP-1 transcription factors.	Front Cell Dev Biol, 2023, 11:1089945 iScience, 2022, 25(5):104293 bioRxiv, 2021, 10.1101/2021.06.28.450163
S9490	Cobalt chloride	Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation. Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1α and AP-1 and iNOS signaling.Cobalt chloride can be used to induce animal models of High-altitude Polycythemia (HAPC).This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	Clin Transl Med, 2024, 14(2):e1567 J Transl Med, 2024, 22(1):245
S9193	Aristolochic acid A	Aristolochic acid A (Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736) is a carcinogenic, mutagenic, and nephrotoxic agent extracted from the flowering plant family Aristolochiaceae.Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and nuclear factor-κB (NF-κB) activities.	Mol Ther Nucleic Acids, 2020, 6;19:1276-1289 Am J Physiol Renal Physiol, 2020, 319(6):F1003-F1014
S0249	Mycro 3	Mycro 3 is a potent and selective inhibitor of c-Myc in whole cell assays. Mycro 3 also shows weak inhibitory activity against AP-1.	J Biol Chem, 2025, S0021-9258(25)00377-1
S7468^New	SR 11302	SR 11302は活性化蛋白質-1（AP-1）転写因子阻害剤です。SR 11302は、レチノイン酸応答エレメント（RARE）の転写を活性化することなく、AP-1活性を特異的に阻害するレチノイドです。
S9721	Farudodstat	Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase) with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosis transcriptional program in acute myeloid leukemia (AML) cells via activation of AP-1 transcription factors.	Front Cell Dev Biol, 2023, 11:1089945 iScience, 2022, 25(5):104293 bioRxiv, 2021, 10.1101/2021.06.28.450163
S9490	Cobalt chloride	Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation. Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1α and AP-1 and iNOS signaling.Cobalt chloride can be used to induce animal models of High-altitude Polycythemia (HAPC).This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	Clin Transl Med, 2024, 14(2):e1567 J Transl Med, 2024, 22(1):245
S0855	TC-E 5003	TC-E 5003 (NSC 30176, Compound 2e) is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) with IC50 of 1.5 μM. TC-E 5003 modulates the lipopolysaccharide (LPS)-induced AP-1 and NF-κB signaling pathways and can possibly be further developed as an anti-inflammatory compound.	Biol Direct, 2025, 20(1):60 Hepatol Commun, 2025, 9(4)e0647 Mol Ther, 2023, 10.1016/j.ymthe.2023.09.011
F3379^New	Fos B Antibody [G14F16]
S7468^New	SR 11302	SR 11302は活性化蛋白質-1（AP-1）転写因子阻害剤です。SR 11302は、レチノイン酸応答エレメント（RARE）の転写を活性化することなく、AP-1活性を特異的に阻害するレチノイドです。