MALT
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S8898 | MLT-748 | <1 mg/mL | 98 mg/mL | 10 mg/mL |
| S7429 | MI-2 (MALT1 inhibitor) | <1 mg/mL | 91 mg/mL | 91 mg/mL |
| S9896 | JNJ-67856633 | <1 mg/mL | 93 mg/mL | ''93 mg/mL |
亜型選択性的な製品
MALT製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S8898 |
MLT-748MLT-748 is a potent, selective and allosteric inhibitor of MALT1 with IC50 of 5 nM, binding at the interface between the caspase and immunoglobulin (Ig3) domains by displacing Trp580 and locking the catalytic site in an inactive state. |
||
| S7429 |
MI-2 (MALT1 inhibitor)MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor with IC50 of 5.84 μM. |
(a-b) Cell growth analysis via MTT assay. Melanoma cell lines, including A2028, A375, WM35, Skmel28, CRL7625 and CRL7626, were seeded in 96-well dishes, and treated in tetrads for 48 hours with varying doses of MI-2. Graph represents average percent of live cells normalized to the untreated group +/- SD.
|
|
| S9896新 |
JNJ-67856633JNJ-67856633 (JNJ-6633) is a potent, selective, allosteric inhibitor of MALT1 protease. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S8898 |
MLT-748MLT-748 is a potent, selective and allosteric inhibitor of MALT1 with IC50 of 5 nM, binding at the interface between the caspase and immunoglobulin (Ig3) domains by displacing Trp580 and locking the catalytic site in an inactive state. |
||
| S7429 |
MI-2 (MALT1 inhibitor)MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor with IC50 of 5.84 μM. |
(a-b) Cell growth analysis via MTT assay. Melanoma cell lines, including A2028, A375, WM35, Skmel28, CRL7625 and CRL7626, were seeded in 96-well dishes, and treated in tetrads for 48 hours with varying doses of MI-2. Graph represents average percent of live cells normalized to the untreated group +/- SD.
|
|
| S9896新 |
JNJ-67856633JNJ-67856633 (JNJ-6633) is a potent, selective, allosteric inhibitor of MALT1 protease. |
