ホームページ ペプチド製品 Rusfertide(PTG-300) For research use only.

Rusfertide(PTG-300)

Rusfertide (PTG-300) is a hepcidin mimetic that targets ferroportin, inducing its internalization and degradation to block cellular iron export into the blood. By limiting transferrin saturation (TSAT), it reduces systemic labile iron toxicity and prevents organ iron deposition. Rusfertide exhibits the potential treatment for Hereditary Hemochromatosis and hemoglobinopathies like beta-thalassemia and also helps to improve anemia by promoting more effective erythropoiesis.

Amino-acid Sequence

PTG-300

化学構造

CAS No. 1628323-80-7

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代表番号: 045-509-1970|電子メール：sales@selleck.co.jp

製品安全説明書

現在のバッチを見る： P125401 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] Insoluble] false 純度： 98.75%
98.75

化学情報

保管

In vitro
Batch:

DMSO : 100 mg/mL ( (40.95 mM)； 吸湿したDMSOは溶解度を減少させます。新しいDMSOをご使用ください。)

Water : 100 mg/mL

Ethanol : Insoluble

モル濃度計算器

in vivo
Batch:

Add solvents to the product individually and in order.

投与溶液組成計算機

生物活性

製品説明 Rusfertide (PTG-300) is a hepcidin mimetic that targets ferroportin, inducing its internalization and degradation to block cellular iron export into the blood. By limiting transferrin saturation (TSAT), it reduces systemic labile iron toxicity and prevents organ iron deposition. Rusfertide exhibits the potential treatment for Hereditary Hemochromatosis and hemoglobinopathies like beta-thalassemia and also helps to improve anemia by promoting more effective erythropoiesis.
  • https://www.sciencedirect.com/science/article/pii/S0006497118614685
  • https://pubmed.ncbi.nlm.nih.gov/39546273/

製品情報

Molecular Formula

C114H181N27O28S2
Molecular Weight 2441.96
CAS No. 1628323-80-7
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
united states