YAP

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1786 Verteporfin <1 mg/mL 100 mg/mL '''<1 mg/mL
S8951 TED-347 ˂1 mg/mL 69 mg/mL ''25 mg/mL
S8554 Super-TDU 100 mg/mL -1 mg/mL '-1 mg/mL
S8164 YAP-TEAD Inhibitor 1 (Peptide 17) 100 mg/mL -1 mg/mL '-1 mg/mL
S8661 CA3(CIL56) <1 mg/mL 97 mg/mL ''<1 mg/mL

YAP製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1786

Verteporfin

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis.

S8951

TED-347

TED-347 is a potent, irreversible, covalent and allosteric inhibitor of the TEAD⋅Yap protein-protein interaction. TED-347 inhibits TEAD4⋅Yap1 protein-protein interaction with an apparent EC50 of 5.9 μM.

S8554

Super-TDU

Super-TDU is an inhibitory peptide targeting YAP-TEADs interaction.

S8164

YAP-TEAD Inhibitor 1 (Peptide 17)

Peptide 17 is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM.

S8661

CA3(CIL56)

CA3(CIL56) has potent inhibitory effects on YAP1/Tead transcriptional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties. CA3(CIL56) induces ferroptosis and iron-dependent reactive oxygen species (ROS).

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1786

Verteporfin

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis.

S8951

TED-347

TED-347 is a potent, irreversible, covalent and allosteric inhibitor of the TEAD⋅Yap protein-protein interaction. TED-347 inhibits TEAD4⋅Yap1 protein-protein interaction with an apparent EC50 of 5.9 μM.

S8554

Super-TDU

Super-TDU is an inhibitory peptide targeting YAP-TEADs interaction.

S8164

YAP-TEAD Inhibitor 1 (Peptide 17)

Peptide 17 is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM.

S8661

CA3(CIL56)

CA3(CIL56) has potent inhibitory effects on YAP1/Tead transcriptional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties. CA3(CIL56) induces ferroptosis and iron-dependent reactive oxygen species (ROS).

Tags: YAP antagonist | YAP inhibitor | YAP agonist | YAP activator