アドレナリン受容体

信号経路図

研究分野

阻害剤の選択性比較
溶解度

カタログ番号	製品カタログ	溶解度(25°C)
カタログ番号	製品カタログ	水	DMSO	アルコール
S2507	Salbutamol Sulfate	68 mg/mL	<1 mg/mL	<1 mg/mL
S1324	Doxazosin Mesylate	<1 mg/mL	15 mg/mL	<1 mg/mL
S1283	Asenapine maleate	<1 mg/mL	80 mg/mL	<1 mg/mL
S4009	Mirabegron	<1 mg/mL	79 mg/mL	8 mg/mL
S2516	Xylazine HCl	12 mg/mL	50 mg/mL	50 mg/mL
S4729	Tamsulosin hydrochloride	17 mg/mL	88 mg/mL	8 mg/mL
S1409	Alfuzosin HCl	85 mg/mL	85 mg/mL	85 mg/mL
S3083	Indacaterol Maleate	<1 mg/mL	102 mg/mL	<1 mg/mL
S2566	Isoprenaline HCl	50 mg/mL	50 mg/mL	<1 mg/mL
S2020	Formoterol Hemifumarate	<1 mg/mL	80 mg/mL	<1 mg/mL
S1613	Silodosin	<1 mg/mL	99 mg/mL	99 mg/mL
S1549	Nebivolol HCl	<1 mg/mL	88 mg/mL	<1 mg/mL
S2521	Epinephrine Bitartrate	67 mg/mL	67 mg/mL	<1 mg/mL
S2691	BMY 7378 Dihydrochloride	92 mg/mL	92 mg/mL	20 mg/mL
S2458	Clonidine HCl	53 mg/mL	53 mg/mL	53 mg/mL
S1424	Prazosin HCl	<1 mg/mL	4 mg/mL	<1 mg/mL
S4076	Propranolol HCl	6 mg/mL	59 mg/mL	<1 mg/mL
S2038	Phentolamine Mesylate	76 mg/mL	76 mg/mL	76 mg/mL
S3041	Droxidopa	<1 mg/mL	<1 mg/mL	<1 mg/mL
S3075	Dexmedetomidine	40 mg/mL	40 mg/mL	40 mg/mL
S2522	L-Adrenaline	<1 mg/mL	4 mg/mL	<1 mg/mL
S1206	Bisoprolol fumarate	88 mg/mL	88 mg/mL	88 mg/mL
S1856	Metoprolol Tartrate	100 mg/mL	100 mg/mL	31 mg/mL
S2059	Terazosin HCl Dihydrate	<1 mg/mL	26 mg/mL	<1 mg/mL
S1387	Naftopidil DiHCl	<1 mg/mL	41 mg/mL	2 mg/mL
S2517	Maprotiline HCl	<1 mg/mL	63 mg/mL	24 mg/mL
S1831	Carvedilol	<1 mg/mL	81 mg/mL	4 mg/mL
S4113	Desvenlafaxine	<1 mg/mL	37 mg/mL	3 mg/mL
S2569	Phenylephrine HCl	41 mg/mL	41 mg/mL	41 mg/mL
S2126	Naftopidil	<1 mg/mL	79 mg/mL	<1 mg/mL
S2499	Phenoxybenzamine HCl	17 mg/mL	68 mg/mL	68 mg/mL
S2509	Sotalol HCl	61 mg/mL	61 mg/mL	<1 mg/mL
S4123	Timolol Maleate	<1 mg/mL	86 mg/mL	86 mg/mL
S4065	Guanabenz Acetate	<1 mg/mL	58 mg/mL	5 mg/mL
S2519	Naphazoline HCl	49 mg/mL	17 mg/mL	22 mg/mL
S2533	Ritodrine HCl	65 mg/mL	65 mg/mL	65 mg/mL
S2438	Synephrine HCl	41 mg/mL	14 mg/mL	4 mg/mL
S2090	Dexmedetomidine HCl	<1 mg/mL	48 mg/mL	48 mg/mL
S4010	Acebutolol HCl	75 mg/mL	75 mg/mL	75 mg/mL
S3061	Epinephrine HCl	44 mg/mL	44 mg/mL	7 mg/mL
S3060	Medetomidine HCl	47 mg/mL	12 mg/mL	47 mg/mL
S1437	Tizanidine HCl	15 mg/mL	10 mg/mL	<1 mg/mL
S1827	Betaxolol HCl	69 mg/mL	69 mg/mL	69 mg/mL
S2092	Detomidine HCl	45 mg/mL	45 mg/mL	45 mg/mL
S2545	Scopine	<1 mg/mL	31 mg/mL	<1 mg/mL
S4296	Salmeterol Xinafoate	<1 mg/mL	100 mg/mL	4 mg/mL
S2607	Buflomedil HCl	69 mg/mL	31 mg/mL	7 mg/mL
S2523	DL-Adrenaline	<1 mg/mL	0.02 mg/mL	<1 mg/mL
S4266	Brimonidine Tartrate	75 mg/mL	88 mg/mL	<1 mg/mL
S2615	Noradrenaline bitartrate monohydrate	64 mg/mL	64 mg/mL	<1 mg/mL
S7974	L755507	<1 mg/mL	100 mg/mL	<1 mg/mL
S4124	Tolazoline HCl	39 mg/mL	39 mg/mL	39 mg/mL
S4127	Terbutaline Sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S4135	Clorprenaline HCl	50 mg/mL	50 mg/mL	50 mg/mL
S4043	Tetrahydrozoline HCl	47 mg/mL	12 mg/mL	26 mg/mL
S1642	Methyldopa	<1 mg/mL	2 mg/mL	<1 mg/mL
S2576	Xylometazoline HCl	56 mg/mL	27 mg/mL	56 mg/mL
S4649	Atipamezole hydrochloride	21 mg/mL	12 mg/mL	49 mg/mL
S4650	Atipamezole	<1 mg/mL	42 mg/mL	42 mg/mL
S4693	Guanfacine Hydrochloride	30 mg/mL	56 mg/mL	56 mg/mL
S4679	Terazosin HCl	1 mg/mL	84 mg/mL	<1 mg/mL
S4085	Levobetaxolol HCl	69 mg/mL	69 mg/mL	69 mg/mL
S8114	ICI-118551 Hydrochloride	21 mg/mL	62 mg/mL	62 mg/mL
S4100	Esmolol HCl	66 mg/mL	66 mg/mL	66 mg/mL
S4112	Desvenlafaxine Succinate	<1 mg/mL	80 mg/mL	<1 mg/mL
S4243	Deoxycorticosterone acetate	<1 mg/mL	11 mg/mL	6 mg/mL
S2086	Ivabradine HCl	82 mg/mL	101 mg/mL	101 mg/mL
S2091	Betaxolol	62 mg/mL	62 mg/mL	<1 mg/mL
S4277	Bambuterol HCl	72 mg/mL	80 mg/mL	28 mg/mL
S4278	Carteolol HCl	65 mg/mL	65 mg/mL	<1 mg/mL
S2362	Synephrine	<1 mg/mL	33 mg/mL	2 mg/mL
S2113	Cisatracurium Besylate	47 mg/mL	249 mg/mL	249 mg/mL
S2373	Yohimbine HCl	<1 mg/mL	12 mg/mL	<1 mg/mL
S4291	Labetalol HCl	8 mg/mL	72 mg/mL	7 mg/mL
S3185	Adrenalone HCl	44 mg/mL	44 mg/mL	<1 mg/mL

亜型選択性的な製品

Adrenergic Receptor阻害剤(8)
Adrenergic Receptor拮抗剤(31)
Adrenergic Receptor作動薬(35)
Adrenergic Receptor化学物質(1)
新Adrenergic Receptor製品

製品コード	製品説明	文献中の使用例	お客様のフィードバック
S1324	Doxazosin Mesylate Doxazosin mesylate is an alpha-1 adrenergic receptor blocker.	J Clin Invest, 2013, 123(12):5119-34 Antiviral Res, 2015, 120:140-6 J Ocul Pharmacol Ther, 2017, 33(1):50-56
S4076	Propranolol HCl Propranolol HCl は、競争的選択的でないベータ受容体阻害剤で、IC50 が 12 nMです。
S1206	Bisoprolol fumarate Bisoprolol fumarate is a selective type β1 adrenergic receptor blocker.
S4113	Desvenlafaxine Desvenlafaxineは一種のセロトニン(5-HT)とノルエピネフリン（NE）の再摂取阻害剤で、Ki値が40.2 nMと558.4nMに分かれることです。
S1642	Methyldopa Methyldopaは一種のDOPAデカルボキシラーゼ（decarboxylase）の競争性的な阻害剤で、 ED50値が21.8 mg/kgです。
S4112	Desvenlafaxine Succinate Desvenlafaxine Succinateは一種の新たなセロトニン (5-HT)とNET（norepinephrine transporter）の再摂取阻害剤で、Ki値が40.2 nMと558.4 nMです。
S2086	Ivabradine HCl Ivabradine HCl, a new I_f inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.
S2113	Cisatracurium Besylate Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
S1283	Asenapine maleate Asenapine maleateは一種の高度親和力セロトニン、ノルエピネフリン（norepinephrine）、ドパミンとヒスタミンの受容体拮抗剤ですが、精神分裂症と急性マニア（acute mania）関連の躁鬱病の治療に使用します。
S4729^新	Tamsulosin hydrochloride	Prostate, 2016, 76(8):757-66	The presence of autophagosomes was visualized by fluorescent microscopy. (Cytotoxicity, caspase-3 activity and autophagy induced by treatment of PC-3 and LNCap cells with prazosin or doxazosin for 24 hr)
S1409	Alfuzosin HCl Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).	Prostate, 2016, 76(8):757-66	PC-3 and LNCaP cell viability following treatment with a1-adrenoceptor antagonists. (A) Cells were treated with drug (0.01-100 μM) for 72 hr and cell viability determined using the resazurin reduction assay. (B) Effect of treatment duration on PC-3 and LNCap cell survival following treatment with doxazosin (30 μM) or prazosin (30 μM). Survival is expressed as the percentage values of untreated vehicle control and values are the mean ( sem) of six independent determinations each conducted in triplicate. P<0.05, **P<0.001 compared to corresponding values for LNCap cells.
S1613	Silodosin Silodosin is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.
S1549	Nebivolol HCl Nebivolol HClは、ウサギ肺β1-副腎受容体結合実験において0.8nMのIC50価値で活動を妨害しているβ1つのレセプターを選択的にします。
S2691	BMY 7378 Dihydrochloride BMY 7378は一種の多ターゲット阻害剤ですが、α2C-adrenoceptorとα1D-adrenoceptorに作用する時のpKi値が6.54と8.2に分かれます。BMY 7378も一種の混合型5-HT1A受容体作動剤と拮抗剤で、pKi値が8.3です。
S1424	Prazosin HCl Prazosin hydrochloride, a quinazoline derivative, is the first of a new chemical class of antihypertensives.
S2038	Phentolamine Mesylate Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM.
S1856	Metoprolol Tartrate Metoprolol Tartrate is a cardioselective β-adrenergic receptor blocker with IC50 of 42 ng/mL.
S2059	Terazosin HCl Dihydrate Terazosin HCl is an alpha-adrenergic blocker used to treat high blood pressure and enlarged prostate.
S1387	Naftopidil DiHCl Naftopidil DiHClは、選択的な5-HT_1Aとα₁-アドレナリン受容体＜/b> 敵対者で、IC50 がそれぞれ 0.1 μM と 0.2 μMです。
S2517	Maprotiline HCl Maprotiline HCl is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.
S1831	Carvedilol Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.	Res Pharm Sci, 2015, 10(5):388-96
S2126	Naftopidil Naftopidil is a selective α1-adrenergic receptor antagonist or alpha blocker with a Ki of 58.3 nM.
S2499	Phenoxybenzamine HCl Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
S2509	Sotalol HCl Sotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM	Toxicol Appl Pharmacol, 2015, 285(1):51-60
S4123	Timolol Maleate Timolol Maleateは、選択的でない、ベータアドレナリンによるレセプターの敵対者で、β1/β2のため、K_i が 1.97 nM/2.0 nMです。
S4010	Acebutolol HCl Acebutolol HCl は、ベータ受容体高血圧、狭心症と心臓不整脈の処置において使われる敵対者。
S1827	Betaxolol HCl Betaxolol HCl is a β₁ adrenergic receptor blocker with IC50 of 6 μM.
S2607	Buflomedil HCl Buflomedil is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.
S4124	Tolazoline HCl Tolazoline HClは、選択的でない競争的α-アドレナリン受容体敵対者です。
S4649	Atipamezole hydrochloride Atipamezole hydrochlorideは1種の合成の α2アドレナリン（adrenergic）受容体拮抗剤で、潜在的な抗パーキンソン薬として、人間に研究されます。Atipamezole hydrochlorideはhydrochlorideのアチパメゾール（atipamezole）形式です。
S4650	Atipamezole Atipamezole は1種の合成の α2アドレナリン（adrenergic）受容体拮抗剤で、潜在的な抗パーキンソン薬として、人間に研究されます。
S4679	Terazosin HCl Terazosinは1種のセレクティブalpha-1拮抗剤（antagonist）で、前立腺腫大(BPH)症の治療に使用されます。Terazosinは膀胱平滑筋と血管壁でのアドレナリン（adrenaline）の作用を抑制することを通じて、役に立ちます。
S4085	Levobetaxolol HCl Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with K_i value of 0.76 nM and 32.6 nM, respectively.
S8114	ICI-118551 Hydrochloride
S4100	Esmolol HCl Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.
S2091	Betaxolol Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
S4278	Carteolol HCl Carteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma.
S2373	Yohimbine HCl Yohimbine HCl has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
S4291	Labetalol HCl Labetalol HCl is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.
S2507	Salbutamol Sulfate Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.
S4009	Mirabegron Mirabegronは、選択的なbeta3-副腎受容体作用薬で、EC50 が 22.4 nMです。
S2516	Xylazine HCl Xylazine HCl is α2 class of adrenergic receptor agonist.	Biomed Rep, 2016, 5(3):357-360 Acad Radiol, 2012, 19(3):358-65
S3083	Indacaterol Maleate Indacaterol Maleateis an ultra-long-acting β-adrenoceptor agonist with pK_i of 7.36.
S2566	Isoprenaline HCl Isoprenaline HClは非選択β-アドレナリン受容体、^{3 ^{H-イノシトールリン酸の蓄積を阻害して、IC50 が0.08 μMです。}}
S2020	Formoterol Hemifumarate Formoterol hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist to β2 and β1 receptors with pKd of 8.12 and 5.58, respectively.
S2521	Epinephrine Bitartrate Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.
S2458	Clonidine HCl Clonidine HClは一種の直接に役立つα2アドレナリン作動薬で、ED50値が0.02±0.01 mg/kgです。
S3041	Droxidopa Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).
S3075	Dexmedetomidine Dexmedetomidine is a sedative medication used by intensive care units and anesthetists.
S2522	L-Adrenaline L-Adrenaline belongs to a group of the compounds known as catecholamines.
S2569	Phenylephrine HCl Phenylephrine HCl is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.
S4065	Guanabenz Acetate Guanabenz Acetate はα2a-アドレナリン受容体、α2b-アドレナリン受容体、α2c-アドレナリン受容体の選択的な作用薬、 pEC50 がそれぞれ 8.25、 7.01 、 ~5です。
S2519	Naphazoline HCl Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.
S2533	Ritodrine HCl Ritodrine HCl is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.
S2438	Synephrine HCl Synephrine HClは、交感神経興奮剤α-アドレナリン受容体（AR、α-副腎受容体）作用薬です。
S2090	Dexmedetomidine HCl Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
S3061	Epinephrine HCl Epinephrine HCl is a hormone and a neurotransmitter.
S3060	Medetomidine HCl Medetomidine HCl is a selective α2-adrenoceptor agonist, with K_i of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
S1437	Tizanidine HCl Tizanidine HCl is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.
S2092	Detomidine HCl Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
S2545	Scopine Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.
S4296	Salmeterol Xinafoate Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.
S2523	DL-Adrenaline DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands.
S4266	Brimonidine Tartrate Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.
S2615	Noradrenaline bitartrate monohydrate Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.
S7974	L755507 L-755507 は1種の有効的で、セレクティブβ3アドレナリン（adrenergic）受容体の部分刺激剤（EC50値：0.43 nM）です。L-755507 はiPSCsと他の細胞類型でCRISPR媒介のホモロジー再編成（homology-directed）の修復効率を増強できます。
S4127	Terbutaline Sulfate Terbutaline Sulfateは、選択的β2-アドレナリン受容体のアゴニストで、IC50 が 53 nMです。
S4135	Clorprenaline HCl Clorprenaline HClは、β2-受容体アゴニストである、それは、気管支の効果を大幅に拡大しています。
S4043	Tetrahydrozoline HCl Tetrahydrozoline HCl 、アルファ受容体アゴニスト活性を有するイミダゾリン誘導体です。
S2576	Xylometazoline HCl Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α_2B-adrenoceptor subtype with EC50 of 4 μM.
S4693	Guanfacine Hydrochloride Guanfacine Hydrochlorideは1種のセレクティブα2Aアドレナリン受容体刺激薬で、抗高血圧効果を持っています。
S4277	Bambuterol HCl Bambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma.
S2362	Synephrine Synephrine is a compound commonly used for weight loss.
S3185	Adrenalone HCl Adrenalone HCl is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.
S4243	Deoxycorticosterone acetate Deoxycorticosterone acetateは、副腎皮質ステロイドの補充療法のための筋肉内注射のために使用ステロイドホルモンです。

製品コード	製品説明	文献中の使用例
S1324	Doxazosin Mesylate Doxazosin mesylate is an alpha-1 adrenergic receptor blocker.	J Clin Invest, 2013, 123(12):5119-34 Antiviral Res, 2015, 120:140-6 J Ocul Pharmacol Ther, 2017, 33(1):50-56
S4076	Propranolol HCl Propranolol HCl は、競争的選択的でないベータ受容体阻害剤で、IC50 が 12 nMです。
S1206	Bisoprolol fumarate Bisoprolol fumarate is a selective type β1 adrenergic receptor blocker.
S4113	Desvenlafaxine Desvenlafaxineは一種のセロトニン(5-HT)とノルエピネフリン（NE）の再摂取阻害剤で、Ki値が40.2 nMと558.4nMに分かれることです。
S1642	Methyldopa Methyldopaは一種のDOPAデカルボキシラーゼ（decarboxylase）の競争性的な阻害剤で、 ED50値が21.8 mg/kgです。
S4112	Desvenlafaxine Succinate Desvenlafaxine Succinateは一種の新たなセロトニン (5-HT)とNET（norepinephrine transporter）の再摂取阻害剤で、Ki値が40.2 nMと558.4 nMです。
S2086	Ivabradine HCl Ivabradine HCl, a new I_f inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.
S2113	Cisatracurium Besylate Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

製品コード	製品説明	文献中の使用例	お客様のフィードバック
S1283	Asenapine maleate Asenapine maleateは一種の高度親和力セロトニン、ノルエピネフリン（norepinephrine）、ドパミンとヒスタミンの受容体拮抗剤ですが、精神分裂症と急性マニア（acute mania）関連の躁鬱病の治療に使用します。
S4729^新	Tamsulosin hydrochloride	Prostate, 2016, 76(8):757-66	The presence of autophagosomes was visualized by fluorescent microscopy. (Cytotoxicity, caspase-3 activity and autophagy induced by treatment of PC-3 and LNCap cells with prazosin or doxazosin for 24 hr)
S1409	Alfuzosin HCl Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).	Prostate, 2016, 76(8):757-66	PC-3 and LNCaP cell viability following treatment with a1-adrenoceptor antagonists. (A) Cells were treated with drug (0.01-100 μM) for 72 hr and cell viability determined using the resazurin reduction assay. (B) Effect of treatment duration on PC-3 and LNCap cell survival following treatment with doxazosin (30 μM) or prazosin (30 μM). Survival is expressed as the percentage values of untreated vehicle control and values are the mean ( sem) of six independent determinations each conducted in triplicate. P<0.05, **P<0.001 compared to corresponding values for LNCap cells.
S1613	Silodosin Silodosin is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.
S1549	Nebivolol HCl Nebivolol HClは、ウサギ肺β1-副腎受容体結合実験において0.8nMのIC50価値で活動を妨害しているβ1つのレセプターを選択的にします。
S2691	BMY 7378 Dihydrochloride BMY 7378は一種の多ターゲット阻害剤ですが、α2C-adrenoceptorとα1D-adrenoceptorに作用する時のpKi値が6.54と8.2に分かれます。BMY 7378も一種の混合型5-HT1A受容体作動剤と拮抗剤で、pKi値が8.3です。
S1424	Prazosin HCl Prazosin hydrochloride, a quinazoline derivative, is the first of a new chemical class of antihypertensives.
S2038	Phentolamine Mesylate Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM.
S1856	Metoprolol Tartrate Metoprolol Tartrate is a cardioselective β-adrenergic receptor blocker with IC50 of 42 ng/mL.
S2059	Terazosin HCl Dihydrate Terazosin HCl is an alpha-adrenergic blocker used to treat high blood pressure and enlarged prostate.
S1387	Naftopidil DiHCl Naftopidil DiHClは、選択的な5-HT_1Aとα₁-アドレナリン受容体＜/b> 敵対者で、IC50 がそれぞれ 0.1 μM と 0.2 μMです。
S2517	Maprotiline HCl Maprotiline HCl is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.
S1831	Carvedilol Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.	Res Pharm Sci, 2015, 10(5):388-96
S2126	Naftopidil Naftopidil is a selective α1-adrenergic receptor antagonist or alpha blocker with a Ki of 58.3 nM.
S2499	Phenoxybenzamine HCl Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
S2509	Sotalol HCl Sotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM	Toxicol Appl Pharmacol, 2015, 285(1):51-60
S4123	Timolol Maleate Timolol Maleateは、選択的でない、ベータアドレナリンによるレセプターの敵対者で、β1/β2のため、K_i が 1.97 nM/2.0 nMです。
S4010	Acebutolol HCl Acebutolol HCl は、ベータ受容体高血圧、狭心症と心臓不整脈の処置において使われる敵対者。
S1827	Betaxolol HCl Betaxolol HCl is a β₁ adrenergic receptor blocker with IC50 of 6 μM.
S2607	Buflomedil HCl Buflomedil is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.
S4124	Tolazoline HCl Tolazoline HClは、選択的でない競争的α-アドレナリン受容体敵対者です。
S4649	Atipamezole hydrochloride Atipamezole hydrochlorideは1種の合成の α2アドレナリン（adrenergic）受容体拮抗剤で、潜在的な抗パーキンソン薬として、人間に研究されます。Atipamezole hydrochlorideはhydrochlorideのアチパメゾール（atipamezole）形式です。
S4650	Atipamezole Atipamezole は1種の合成の α2アドレナリン（adrenergic）受容体拮抗剤で、潜在的な抗パーキンソン薬として、人間に研究されます。
S4679	Terazosin HCl Terazosinは1種のセレクティブalpha-1拮抗剤（antagonist）で、前立腺腫大(BPH)症の治療に使用されます。Terazosinは膀胱平滑筋と血管壁でのアドレナリン（adrenaline）の作用を抑制することを通じて、役に立ちます。
S4085	Levobetaxolol HCl Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with K_i value of 0.76 nM and 32.6 nM, respectively.
S8114	ICI-118551 Hydrochloride
S4100	Esmolol HCl Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.
S2091	Betaxolol Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
S4278	Carteolol HCl Carteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma.
S2373	Yohimbine HCl Yohimbine HCl has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
S4291	Labetalol HCl Labetalol HCl is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.

製品コード	製品説明	文献中の使用例
S2507	Salbutamol Sulfate Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.
S4009	Mirabegron Mirabegronは、選択的なbeta3-副腎受容体作用薬で、EC50 が 22.4 nMです。
S2516	Xylazine HCl Xylazine HCl is α2 class of adrenergic receptor agonist.	Biomed Rep, 2016, 5(3):357-360 Acad Radiol, 2012, 19(3):358-65
S3083	Indacaterol Maleate Indacaterol Maleateis an ultra-long-acting β-adrenoceptor agonist with pK_i of 7.36.
S2566	Isoprenaline HCl Isoprenaline HClは非選択β-アドレナリン受容体、^{3 ^{H-イノシトールリン酸の蓄積を阻害して、IC50 が0.08 μMです。}}
S2020	Formoterol Hemifumarate Formoterol hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist to β2 and β1 receptors with pKd of 8.12 and 5.58, respectively.
S2521	Epinephrine Bitartrate Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.
S2458	Clonidine HCl Clonidine HClは一種の直接に役立つα2アドレナリン作動薬で、ED50値が0.02±0.01 mg/kgです。
S3041	Droxidopa Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).
S3075	Dexmedetomidine Dexmedetomidine is a sedative medication used by intensive care units and anesthetists.
S2522	L-Adrenaline L-Adrenaline belongs to a group of the compounds known as catecholamines.
S2569	Phenylephrine HCl Phenylephrine HCl is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.
S4065	Guanabenz Acetate Guanabenz Acetate はα2a-アドレナリン受容体、α2b-アドレナリン受容体、α2c-アドレナリン受容体の選択的な作用薬、 pEC50 がそれぞれ 8.25、 7.01 、 ~5です。
S2519	Naphazoline HCl Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.
S2533	Ritodrine HCl Ritodrine HCl is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.
S2438	Synephrine HCl Synephrine HClは、交感神経興奮剤α-アドレナリン受容体（AR、α-副腎受容体）作用薬です。
S2090	Dexmedetomidine HCl Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
S3061	Epinephrine HCl Epinephrine HCl is a hormone and a neurotransmitter.
S3060	Medetomidine HCl Medetomidine HCl is a selective α2-adrenoceptor agonist, with K_i of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
S1437	Tizanidine HCl Tizanidine HCl is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.
S2092	Detomidine HCl Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
S2545	Scopine Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.
S4296	Salmeterol Xinafoate Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.
S2523	DL-Adrenaline DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands.
S4266	Brimonidine Tartrate Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.
S2615	Noradrenaline bitartrate monohydrate Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.
S7974	L755507 L-755507 は1種の有効的で、セレクティブβ3アドレナリン（adrenergic）受容体の部分刺激剤（EC50値：0.43 nM）です。L-755507 はiPSCsと他の細胞類型でCRISPR媒介のホモロジー再編成（homology-directed）の修復効率を増強できます。
S4127	Terbutaline Sulfate Terbutaline Sulfateは、選択的β2-アドレナリン受容体のアゴニストで、IC50 が 53 nMです。
S4135	Clorprenaline HCl Clorprenaline HClは、β2-受容体アゴニストである、それは、気管支の効果を大幅に拡大しています。
S4043	Tetrahydrozoline HCl Tetrahydrozoline HCl 、アルファ受容体アゴニスト活性を有するイミダゾリン誘導体です。
S2576	Xylometazoline HCl Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α_2B-adrenoceptor subtype with EC50 of 4 μM.
S4693	Guanfacine Hydrochloride Guanfacine Hydrochlorideは1種のセレクティブα2Aアドレナリン受容体刺激薬で、抗高血圧効果を持っています。
S4277	Bambuterol HCl Bambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma.
S2362	Synephrine Synephrine is a compound commonly used for weight loss.
S3185	Adrenalone HCl Adrenalone HCl is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.

製品コード	製品説明	文献中の使用例	お客様のフィードバック
S4243	Deoxycorticosterone acetate Deoxycorticosterone acetateは、副腎皮質ステロイドの補充療法のための筋肉内注射のために使用ステロイドホルモンです。

製品コード

製品説明

文献中の使用例

お客様のフィードバック

S4243

Deoxycorticosterone acetate

Deoxycorticosterone acetateは、副腎皮質ステロイドの補充療法のための筋肉内注射のために使用ステロイドホルモンです。

研究分野別

製品類型

アドレナリン受容体

信号経路図

研究分野

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