アドレナリン受容体
- 阻害剤の選択性比較
- 溶解度
カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
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水 | DMSO | アルコール | ||
S2507 | Salbutamol Sulfate | 68 mg/mL | <1 mg/mL | <1 mg/mL |
S1324 | Doxazosin Mesylate | <1 mg/mL | 15 mg/mL | <1 mg/mL |
S1283 | Asenapine maleate | <1 mg/mL | 80 mg/mL | <1 mg/mL |
S4009 | Mirabegron | <1 mg/mL | 79 mg/mL | 8 mg/mL |
S2516 | Xylazine HCl | 12 mg/mL | 50 mg/mL | 50 mg/mL |
S3960 | Higenamine hydrochloride | -1 mg/mL | 61 mg/mL | -1 mg/mL |
S3643 | Amitraz | <1 mg/mL | 58 mg/mL | <1 mg/mL |
S3664 | Flupenthixol dihydrochloride | 100 mg/mL | 100 mg/mL | 30 mg/mL |
S3640 | Methoxyphenamine Hydrochloride | 43 mg/mL | 43 mg/mL | 43 mg/mL |
S3727 | Vilanterol Trifenate | <1 mg/mL | 100 mg/mL | 14 mg/mL |
S3656 | Piribedil | <1 mg/mL | 59 mg/mL | 59 mg/mL |
S1409 | Alfuzosin HCl | 85 mg/mL | 85 mg/mL | 85 mg/mL |
S3083 | Indacaterol Maleate | <1 mg/mL | 102 mg/mL | <1 mg/mL |
S2566 | Isoprenaline HCl | 50 mg/mL | 50 mg/mL | <1 mg/mL |
S2020 | Formoterol Hemifumarate | <1 mg/mL | 80 mg/mL | <1 mg/mL |
S1613 | Silodosin | <1 mg/mL | 99 mg/mL | 99 mg/mL |
S1549 | Nebivolol HCl | <1 mg/mL | 88 mg/mL | <1 mg/mL |
S2521 | Epinephrine Bitartrate | 67 mg/mL | 67 mg/mL | <1 mg/mL |
S2691 | BMY 7378 Dihydrochloride | 92 mg/mL | 92 mg/mL | 20 mg/mL |
S2458 | Clonidine HCl | 53 mg/mL | 53 mg/mL | 53 mg/mL |
S1424 | Prazosin HCl | <1 mg/mL | 4 mg/mL | <1 mg/mL |
S4076 | Propranolol HCl | 6 mg/mL | 59 mg/mL | <1 mg/mL |
S2038 | Phentolamine Mesylate | 76 mg/mL | 76 mg/mL | 76 mg/mL |
S3041 | Droxidopa | <1 mg/mL | <1 mg/mL | <1 mg/mL |
S3075 | Dexmedetomidine | <1 mg/mL | 40 mg/mL | 40 mg/mL |
S2522 | L-Adrenaline | <1 mg/mL | 4 mg/mL | <1 mg/mL |
S1206 | Bisoprolol fumarate | 88 mg/mL | 88 mg/mL | 88 mg/mL |
S1856 | Metoprolol Tartrate | 100 mg/mL | 100 mg/mL | 31 mg/mL |
S2059 | Terazosin HCl Dihydrate | <1 mg/mL | 26 mg/mL | <1 mg/mL |
S1387 | Naftopidil DiHCl | <1 mg/mL | 41 mg/mL | 2 mg/mL |
S2517 | Maprotiline HCl | <1 mg/mL | 63 mg/mL | 24 mg/mL |
S1831 | Carvedilol | <1 mg/mL | 81 mg/mL | 4 mg/mL |
S4113 | Desvenlafaxine | <1 mg/mL | 37 mg/mL | 3 mg/mL |
S2569 | Phenylephrine HCl | 41 mg/mL | 41 mg/mL | 41 mg/mL |
S2126 | Naftopidil | <1 mg/mL | 79 mg/mL | <1 mg/mL |
S2499 | Phenoxybenzamine HCl | 17 mg/mL | 68 mg/mL | 68 mg/mL |
S2509 | Sotalol HCl | 61 mg/mL | 61 mg/mL | <1 mg/mL |
S4123 | Timolol Maleate | <1 mg/mL | 86 mg/mL | 86 mg/mL |
S4065 | Guanabenz Acetate | <1 mg/mL | 58 mg/mL | 5 mg/mL |
S2519 | Naphazoline HCl | 49 mg/mL | 17 mg/mL | 22 mg/mL |
S2533 | Ritodrine HCl | 65 mg/mL | 65 mg/mL | 65 mg/mL |
S2438 | Synephrine HCl | 41 mg/mL | 14 mg/mL | 4 mg/mL |
S2090 | Dexmedetomidine HCl | <1 mg/mL | 48 mg/mL | 48 mg/mL |
S4010 | Acebutolol HCl | 75 mg/mL | 75 mg/mL | 75 mg/mL |
S3061 | Epinephrine HCl | 44 mg/mL | 44 mg/mL | 7 mg/mL |
S3060 | Medetomidine HCl | 47 mg/mL | 12 mg/mL | 47 mg/mL |
S1437 | Tizanidine HCl | 15 mg/mL | 10 mg/mL | <1 mg/mL |
S1827 | Betaxolol HCl | 69 mg/mL | 69 mg/mL | 69 mg/mL |
S2092 | Detomidine HCl | 45 mg/mL | 45 mg/mL | 45 mg/mL |
S2545 | Scopine | <1 mg/mL | 31 mg/mL | <1 mg/mL |
S4296 | Salmeterol Xinafoate | <1 mg/mL | 100 mg/mL | 4 mg/mL |
S2607 | Buflomedil HCl | 69 mg/mL | 31 mg/mL | 7 mg/mL |
S2523 | DL-Adrenaline | <1 mg/mL | 0.02 mg/mL | <1 mg/mL |
S4266 | Brimonidine Tartrate | 75 mg/mL | 88 mg/mL | <1 mg/mL |
S2615 | Noradrenaline bitartrate monohydrate | 64 mg/mL | 64 mg/mL | <1 mg/mL |
S7974 | L755507 | <1 mg/mL | 100 mg/mL | <1 mg/mL |
S4729 | Tamsulosin hydrochloride | 17 mg/mL | 88 mg/mL | 8 mg/mL |
S4124 | Tolazoline HCl | 39 mg/mL | 39 mg/mL | 39 mg/mL |
S4127 | Terbutaline Sulfate | 100 mg/mL | <1 mg/mL | <1 mg/mL |
S4135 | Clorprenaline HCl | 50 mg/mL | 50 mg/mL | 50 mg/mL |
S4043 | Tetrahydrozoline HCl | 47 mg/mL | 12 mg/mL | 26 mg/mL |
S1642 | Methyldopa | <1 mg/mL | 2 mg/mL | <1 mg/mL |
S2576 | Xylometazoline HCl | 56 mg/mL | 27 mg/mL | 56 mg/mL |
S4649 | Atipamezole hydrochloride | 21 mg/mL | 12 mg/mL | 49 mg/mL |
S4650 | Atipamezole | <1 mg/mL | 42 mg/mL | 42 mg/mL |
S4693 | Guanfacine Hydrochloride | 30 mg/mL | 56 mg/mL | 56 mg/mL |
S4679 | Terazosin HCl | 1 mg/mL | 84 mg/mL | <1 mg/mL |
S4085 | Levobetaxolol HCl | 69 mg/mL | 69 mg/mL | 69 mg/mL |
S8114 | ICI-118551 Hydrochloride | 21 mg/mL | 62 mg/mL | 62 mg/mL |
S4100 | Esmolol HCl | 66 mg/mL | 66 mg/mL | 66 mg/mL |
S4112 | Desvenlafaxine Succinate | <1 mg/mL | 80 mg/mL | <1 mg/mL |
S4243 | Deoxycorticosterone acetate | <1 mg/mL | 11 mg/mL | 6 mg/mL |
S2086 | Ivabradine HCl | 82 mg/mL | 101 mg/mL | 101 mg/mL |
S2091 | Betaxolol | 62 mg/mL | 62 mg/mL | <1 mg/mL |
S4277 | Bambuterol HCl | 72 mg/mL | 80 mg/mL | 28 mg/mL |
S4278 | Carteolol HCl | 65 mg/mL | 65 mg/mL | <1 mg/mL |
S2362 | Synephrine | <1 mg/mL | 33 mg/mL | 2 mg/mL |
S2113 | Cisatracurium Besylate | 47 mg/mL | 249 mg/mL | 249 mg/mL |
S2373 | Yohimbine HCl | <1 mg/mL | 12 mg/mL | <1 mg/mL |
S4291 | Labetalol HCl | 8 mg/mL | 72 mg/mL | 7 mg/mL |
S3185 | Adrenalone HCl | 44 mg/mL | 44 mg/mL | <1 mg/mL |
- Adrenergic Receptor阻害剤(82)
- 新Adrenergic Receptor製品
製品コード | 製品説明 | 文献中の使用例 | お客様のフィードバック |
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S2507 |
Salbutamol SulfateSalbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM. |
![]() ![]() (B) Bar graphs summarize the incidence of VA from Con (An external file that holds a picture, illustration, etc. Object name is srep07681-m1.jpg) and HF (An external file that holds a picture, illustration, etc. Object name is srep07681-m2.jpg) guinea pigs before and after administration of Sal (10 μM) or Sal plus ICI (1 μM) (*p < 0.05, HF + Sal vs. Con + Sal; #p < 0.05, HF + Sal vs. HF + Sal + ICI, n = 6).
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S1324 |
Doxazosin MesylateDoxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia. |
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S1283 |
Asenapine maleateAsenapine maleate is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder. |
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S4009 |
MirabegronMirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM. |
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S2516 |
Xylazine HClXylazine is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant. |
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S4817新 |
AtenololAtenolol is a selective β1 receptor antagonist with log Kd values of −6.66±0.05, −5.99±0.14, −4.11±0.07 for binding to the human β1-, β2- and β3-adrenoceptors. |
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S3960新 |
Higenamine hydrochlorideHigenamine, also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants. |
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S3643新 |
AmitrazAmitraz is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. It is a non-systemic acaricide and insecticide. |
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S3664新 |
Flupenthixol dihydrochlorideFlupentixol, an antipsychotic neuroleptic drug, is a powerful antagonist of both D1 and D2 dopamine receptors and also an alpha-adrenergic receptor antagonist. |
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S3640新 |
Methoxyphenamine HydrochlorideMethoxyphenamine Hydrochloride is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator. |
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S3727新 |
Vilanterol TrifenateVilanterol trifenatate is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma. |
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S3656新 |
PiribedilPiribedil is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties. |
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S1409 |
Alfuzosin HClAlfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH). |
![]() ![]() PC-3 and LNCaP cell viability following treatment with a1-adrenoceptor antagonists. (A) Cells were treated with drug (0.01-100 μM) for 72 hr and cell viability determined using the resazurin reduction assay. (B) Effect of treatment duration on PC-3 and LNCap cell survival following treatment with doxazosin (30 μM) or prazosin (30 μM). Survival is expressed as the percentage values of untreated vehicle control and values are the mean ( sem) of six independent determinations each conducted in triplicate. *P<0.05, ***P<0.001 compared to corresponding values for LNCap cells.
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S3083 |
Indacaterol MaleateIndacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor. |
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S2566 |
Isoprenaline HClIsoprenaline is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block. |
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S2020 |
Formoterol HemifumarateFormoterol Hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD). |
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S1613 |
SilodosinSilodosin is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia. |
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S1549 |
Nebivolol HClNebivolol HCl selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM. |
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S2521 |
Epinephrine BitartrateEpinephrine bitartrate is an alpha- and beta-adrenergic receptor stimulator. |
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S2691 |
BMY 7378 DihydrochlorideBMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3. |
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S2458 |
Clonidine HClClonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg. |
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S1424 |
Prazosin HClPrazosin HCl is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia. |
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S4076 |
Propranolol HClPropranolol HCl is a competitive non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM. |
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S2038 |
Phentolamine MesylatePhentolamine Mesylate is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes. |
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S3041 |
DroxidopaDroxidopa is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). |
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S3075 |
DexmedetomidineDexmedetomidine is a sedative medication used by intensive care units and anesthetists. |
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S2522 |
L-AdrenalineL-Adrenaline belongs to a group of the compounds known as catecholamines. |
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S1206 |
Bisoprolol fumarateBisoprolol fumarate is a selective type β1 adrenergic receptor blocker. |
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S1856 |
Metoprolol TartrateMetoprolol Tartrate is a selective β1 receptor blocker medication, used to treat hypertension and heart failure. |
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S2059 |
Terazosin HCl DihydrateTerazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH). |
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S1387 |
Naftopidil DiHClNaftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively. |
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S2517 |
Maprotiline HClMaprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression. |
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S1831 |
CarvedilolCarvedilol is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure. |
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S4113 |
DesvenlafaxineDesvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively. |
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S2569 |
Phenylephrine HClPhenylephrine HCl is a selective α1-adrenergic receptor agonist, used primarily as a decongestant. |
![]() ![]() (F) Fluo-4 AM-loaded EPLC-SMCs and HCASMCs displayed a change in cell surface area following phenylephrine stimulation. Scale bars, 100 μm. (G) Percentage change in cell surface area. Error bars represent SEM; n = 12 cells; **p < 0.01 versus D15 + 8 + 6 cells that did not exhibit calcium transients, analyzed by the Student's t-test. HCASMCs, human coronary artery smooth muscle cells; NS, no significant difference.
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S2126 |
NaftopidilNaftopidil is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia. |
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S2499 |
Phenoxybenzamine HClPhenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM. |
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S2509 |
Sotalol HClSotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM. |
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S4123 |
Timolol MaleateTimolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM. |
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S4065 |
Guanabenz AcetateGuanabenz Acetate is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively. |
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S2519 |
Naphazoline HClNaphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine. |
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S2533 |
Ritodrine HClRitodrine HCl is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist. |
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S2438 |
Synephrine HClSynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist. |
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S2090 |
Dexmedetomidine HClDexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation. |
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S4010 |
Acebutolol HClAcebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. |
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S3061 |
Epinephrine HClEpinephrine HCl is a hormone and a neurotransmitter. |
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S3060 |
Medetomidine HClMedetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor. |
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S1437 |
Tizanidine HClTizanidine HCl is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. |
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S1827 |
Betaxolol HClBetaxolol is a β1 adrenergic receptor blocker with IC50 of 6 μM. |
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S2092 |
Detomidine HClDetomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors. |
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S2545 |
ScopineScopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock. |
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S4296 |
Salmeterol XinafoateSalmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. |
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S2607 |
Buflomedil HClBuflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease; A nonselective alpha adrenergic receptor inhibitor. |
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S2523 |
DL-AdrenalineDL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands. |
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S4266 |
Brimonidine TartrateBrimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension. |
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S2615 |
Noradrenaline bitartrate monohydrateNoradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator. |
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S7974 |
L755507L-755,507 is characterized as a potent and selective β3 adrenergic receptor partial agonist with EC50 of 0.43 nM. It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types. |
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S4729 |
Tamsulosin hydrochlorideTamsulosin is a potent and selective α1a adrenergic receptor antagonist. |
![]() ![]() The presence of autophagosomes was visualized by fluorescent microscopy. (Cytotoxicity, caspase-3 activity and autophagy induced by treatment of PC-3 and LNCap cells with prazosin or doxazosin for 24 hr)
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S4124 |
Tolazoline HClTolazoline is a non-selective competitive α-adrenergic receptor antagonist. |
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S4127 |
Terbutaline SulfateTerbutaline Sulfate is a selective β2-adrenergic receptor agonist with IC50 of 53 nM. |
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S4135 |
Clorprenaline HClClorprenaline HCl is a β2-receptor agonist, it has a significant expansion of the bronchial effect. |
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S4043 |
Tetrahydrozoline HClTetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity. |
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S1642 |
MethyldopaMethyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg. |
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S2576 |
Xylometazoline HClXylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM. |
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S4649 |
Atipamezole hydrochlorideAtipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole. |
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S4650 |
AtipamezoleAtipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. |
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S4693 |
Guanfacine HydrochlorideGuanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect. |
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S4679 |
Terazosin HClTerazosin is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls. |
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S4085 |
Levobetaxolol HClLevobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively. |
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S8114 |
ICI-118551 HydrochlorideICI-118551 is a highly selective β2-adrenergic receptor antagonist with Ki values of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively. |
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S4100 |
Esmolol HClEsmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms. |
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S4112 |
Desvenlafaxine SuccinateDesvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively. |
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S4243 |
Deoxycorticosterone acetateDeoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid. |
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S2086 |
Ivabradine HClIvabradine HCl, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent. |
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S2091 |
BetaxololBetaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma. |
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S4277 |
Bambuterol HClBambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma. |
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S4278 |
Carteolol HClCarteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma. |
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S2362 |
SynephrineSynephrine, a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss. |
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S2113 |
Cisatracurium BesylateCisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. |
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S2373 |
Yohimbine HClYohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac. |
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S4291 |
Labetalol HClLabetalol HCl is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure. |
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S3185 |
Adrenalone HClAdrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors. |