Immunology & Inflammation related

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S2286 Cyclosporin A <1 mg/mL 100 mg/mL 100 mg/mL
S5004 Pimecrolimus <1 mg/mL 100 mg/mL 100 mg/mL
S1211 Imiquimod <1 mg/mL 1 mg/mL <1 mg/mL
S3032 Bindarit <1 mg/mL 64 mg/mL 64 mg/mL
S1591 Bestatin <1 mg/mL 0.4 mg/mL <1 mg/mL
S5412 Loxoprofen Sodium 53 mg/mL <1 mg/mL <1 mg/mL
S5361 Bendazac <1 mg/mL 56 mg/mL 56 mg/mL
S5360 Diflorasone <1 mg/mL 82 mg/mL 2 mg/mL
S5466 Saikosaponin A <1 mg/mL 100 mg/mL 100 mg/mL
S5501 Hydrocortisone acetate -1 mg/mL 80 mg/mL -1 mg/mL
S5500 Amodiaquine hydrochloride -1 mg/mL 56 mg/mL -1 mg/mL
S3969 Veratric acid -1 mg/mL 36 mg/mL -1 mg/mL
S7732 ISO-1 <1 mg/mL 47 mg/mL 47 mg/mL
S5322 Sodium gualenate 18 mg/mL 60 mg/mL 1 mg/mL
S5579 Chelidonic acid -1 mg/mL 4 mg/mL -1 mg/mL
S5451 Ferulic acid methyl ester 41 mg/mL 41 mg/mL 41 mg/mL
S5457 Curculigoside 15 mg/mL 93 mg/mL 93 mg/mL
S5458 Verbascoside 100 mg/mL 100 mg/mL 23 mg/mL
S5459 Aucubin 15 mg/mL 69 mg/mL <1 mg/mL
S5463 Curcurbitacin IIA <1 mg/mL 100 mg/mL 5 mg/mL
S5471 Monotropein 78 mg/mL 78 mg/mL <1 mg/mL
S5517 Fenamic acid -1 mg/mL 42 mg/mL -1 mg/mL
S3776 Sophoricoside <1 mg/mL 86 mg/mL <1 mg/mL
S5039 Actarit -1 mg/mL 38 mg/mL -1 mg/mL
S5043 Benorylate -1 mg/mL 62 mg/mL -1 mg/mL
S5083 Lentinan -1 mg/mL 100 mg/mL -1 mg/mL
S5016 Isoprinosine 100 mg/mL 100 mg/mL 2 mg/mL
S5044 Isoxepac <1 mg/mL 53 mg/mL 53 mg/mL
S5046 Clonixin <1 mg/mL 52 mg/mL 15 mg/mL
S4966 4-Methylesculetin -1 mg/mL 38 mg/mL -1 mg/mL
S4832 Tolmetin -1 mg/mL 51 mg/mL -1 mg/mL
S4835 Aceclofenac -1 mg/mL 70 mg/mL -1 mg/mL
S3997 Oxaceprol -1 mg/mL 34 mg/mL -1 mg/mL
S4789 5-Acetylsalicylic acid -1 mg/mL 36 mg/mL -1 mg/mL
S5157 Thymol -1 mg/mL 30 mg/mL -1 mg/mL
S3982 Batyl alcohol -1 mg/mL 68 mg/mL -1 mg/mL
S3906 Astragalus polyphenols -1 mg/mL 81 mg/mL -1 mg/mL
S3877 Lysionotin -1 mg/mL 68 mg/mL -1 mg/mL
S3881 Scopoletin -1 mg/mL 38 mg/mL -1 mg/mL
S3778 Patchouli alcohol -1 mg/mL 44 mg/mL -1 mg/mL
S3790 Methyl gallate -1 mg/mL 36 mg/mL -1 mg/mL
S3799 Gentisic acid -1 mg/mL 30 mg/mL -1 mg/mL
S3765 Picroside II -1 mg/mL 100 mg/mL -1 mg/mL
S3892 Isopsoralen -1 mg/mL 14 mg/mL -1 mg/mL
S3774 Dehydroandrographolide Succinate Potasium Salt -1 mg/mL 10 mg/mL -1 mg/mL
S3775 Ligustrazine hydrochloride -1 mg/mL 34 mg/mL -1 mg/mL
S3758 Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride -1 mg/mL 73 mg/mL -1 mg/mL
S3932 Astilbin -1 mg/mL 100 mg/mL -1 mg/mL
S3837 Echinocystic acid -1 mg/mL 94 mg/mL -1 mg/mL
S3824 Quercitrin -1 mg/mL 89 mg/mL -1 mg/mL
S3827 Royal jelly acid -1 mg/mL 37 mg/mL -1 mg/mL
S3841 Eleutheroside B -1 mg/mL 74 mg/mL -1 mg/mL
S3956 Tetramethylpyrazine -1 mg/mL 27 mg/mL -1 mg/mL
S3614 Lupeol <1 mg/mL 1 mg/mL <1 mg/mL
S3685 4-Biphenylacetic acid <1 mg/mL 42 mg/mL 42 mg/mL
S3680 NLRP3 Inflammasome Inhibitor I <1 mg/mL 73 mg/mL <1 mg/mL
S3745 Balsalazide disodium 87 mg/mL 87 mg/mL <1 mg/mL
S3648 Amlexanox <1 mg/mL 59 mg/mL 1 mg/mL
S3726 Selexipag <1 mg/mL 99 mg/mL 49 mg/mL
S3668 Thymopentin 100 mg/mL 100 mg/mL <1 mg/mL
S3622 Diammonium Glycyrrhizinate 100 mg/mL 100 mg/mL <1 mg/mL
S3608 Demethylzeylasteral (T-96) <1 mg/mL 96 mg/mL 33 mg/mL
S1407 Bimatoprost <1 mg/mL 36 mg/mL 83 mg/mL
S1439 Tranilast <1 mg/mL 66 mg/mL <1 mg/mL
S1737 Prednisolone <1 mg/mL 72 mg/mL 10 mg/mL
S1622 Prednisone <1 mg/mL 71 mg/mL <1 mg/mL
S4169 Teriflunomide <1 mg/mL 32 mg/mL ,1 mg/mL
S2413 Geniposidic acid <1 mg/mL 16 mg/mL 2 mg/mL
S1508 Alprostadil <1 mg/mL 71 mg/mL 71 mg/mL
S1733 Methylprednisolone <1 mg/mL 75 mg/mL 2 mg/mL
S1939 (-)-Tetramisole 48 mg/mL <1 mg/mL <1 mg/mL
S2787 Laquinimod <1 mg/mL 61 mg/mL 1 mg/mL
S1681 Mesalamine <1 mg/mL 31 mg/mL 31 mg/mL
S2910 Tempol 34 mg/mL 34 mg/mL 34 mg/mL
S1679 Flurbiprofen <1 mg/mL 49 mg/mL 49 mg/mL
S1829 Pranlukast <1 mg/mL 11 mg/mL <1 mg/mL
S1514 Cyclosporine <1 mg/mL 100 mg/mL 100 mg/mL
S1576 Sulfasalazine <1 mg/mL 80 mg/mL <1 mg/mL
S1654 Phenylbutazone <1 mg/mL 62 mg/mL 62 mg/mL
S2512 Tenoxicam <1 mg/mL 68 mg/mL <1 mg/mL
S3062 Diclofenac Potassium 10 mg/mL 69 mg/mL <1 mg/mL
S7515 VGX-1027 <1 mg/mL 41 mg/mL 41 mg/mL
S4098 Halcinonide <1 mg/mL 90 mg/mL 4 mg/mL
S1823 Fenoprofen Calcium <1 mg/mL 105 mg/mL 10 mg/mL
S8301 AS101 <1 mg/mL 62 mg/mL <1 mg/mL
S4268 Flufenamic acid <1 mg/mL 56 mg/mL 56 mg/mL
S4529 Idramantone 33 mg/mL 33 mg/mL 33 mg/mL
S7211 PF-04418948 <1 mg/mL 81 mg/mL <1 mg/mL
S4152 Ethamsylate 53 mg/mL 53 mg/mL <1 mg/mL
S2383 Gastrodin <1 mg/mL 50 mg/mL <1 mg/mL
S2387 Lappaconite HBr <1 mg/mL 28 mg/mL <1 mg/mL
S4165 Benzydamine HCl 69 mg/mL 69 mg/mL 69 mg/mL
S4170 Coumarin <1 mg/mL 29 mg/mL 29 mg/mL
S7809 MCC950(CP-456773) 85 mg/mL <1 mg/mL 40 mg/mL
S2400 Rheic Acid <1 mg/mL <1 mg/mL <1 mg/mL
S4188 Sasapyrine <1 mg/mL 52 mg/mL 52 mg/mL
S7448 CORM-3 <1 mg/mL 38 mg/mL <1 mg/mL
S4682 Loxoprofen <1 mg/mL 49 mg/mL 49 mg/mL
S8291 Atractylenolide I <1 mg/mL 46 mg/mL 46 mg/mL
S7516 Y-320 <1 mg/mL 11 mg/mL <1 mg/mL
S8141 Cl-amidine 70 mg/mL 84 mg/mL 84 mg/mL
S3027 Fenoprofen calcium hydrate <1 mg/mL 48 mg/mL 18 mg/mL
S8522 Compstatin 100 mg/mL -1 mg/mL -1 mg/mL
S4753 Ganoderic acid A <1 mg/mL 100 mg/mL 100 mg/mL
S8097 C-DIM12 <1 mg/mL 71 mg/mL 71 mg/mL
S2350 Rutin <1 mg/mL 100 mg/mL 2 mg/mL
S3106 Pidotimod 10 mg/mL 49 mg/mL <1 mg/mL
S4515 Ademetionine disulfate tosylate 79 mg/mL 79 mg/mL <1 mg/mL
S7434 TAPI-1 60 mg/mL 99 mg/mL 99 mg/mL
S4690 Escin <1 mg/mL 66 mg/mL <1 mg/mL
製品コード 製品説明 文献中の使用例 お客様のフィードバック
S2286

Cyclosporin A

Cyclosporin A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.

S5004

Pimecrolimus

Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12 (FKBP-12); a calcineurin inhibitor.

S1211

Imiquimod

Imiquimod is a novel synthetic agent with immune response modifying activity.

S3032

Bindarit

Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.

S1591

Bestatin

Bestatin is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor, used in the treatment of acute myelocytic leukemia.

S5412

Loxoprofen Sodium

S5361

Bendazac

S5360

Diflorasone

S5466

Saikosaponin A

S5501

Hydrocortisone acetate

S5500

Amodiaquine hydrochloride

S3969

Veratric acid

S7732

ISO-1

S5322

Sodium gualenate

S5579

Chelidonic acid

S5451

Ferulic acid methyl ester

S5457

Curculigoside

S5458

Verbascoside

S5459

Aucubin

S5463

Curcurbitacin IIA

S5471

Monotropein

S5517

Fenamic acid

S5261

Ufenamate

S5318

Acacetin

S3776

Sophoricoside

S5039

Actarit

S5043

Benorylate

S5083

Lentinan

S5016

Isoprinosine

S5044

Isoxepac

S5046

Clonixin

S4966

4-Methylesculetin

S4832

Tolmetin

S4835

Aceclofenac

S3997

Oxaceprol

Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.

S4789

5-Acetylsalicylic acid

5-Acetylsalicylic acid, also known as Mesalazine or Mesalamine, is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease.

S5157

Thymol

Thymol, a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro.

S3982

Batyl alcohol

Batyl alcohol, isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.

S3906

Astragalus polyphenols

Astragalus is a wonderful immune enhancing herb that has strong anti-viral activity and produces extra interferon in the body. It contains rich polyphenol with various effects including antioxidant and antiinflammatory actions.

S3877

Lysionotin

Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.

S3881

Scopoletin

Scopoletin is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.

S3813

Bakuchiol

Bakuchiol is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has anti-inflammatory and antimicrobial activities.

S3778

Patchouli alcohol

Patchouli alcohol, an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.

S3790

Methyl gallate

Methyl Gallate is a plant polyphenol with antioxidant, anticancer, and anti-inflammatory activities.

S3799

Gentisic acid

Gentisic acid, an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.

S3765

Picroside II

Picroside II is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.

S3892

Isopsoralen

Isopsoralen, also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses.

S3774

Dehydroandrographolide Succinate Potasium Salt

Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.

S3775

Ligustrazine hydrochloride

Tetramethylpyrazine, also known as ligustrazine, is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.

S3758

Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride

Sinomenine (SN), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.

S3932

Astilbin

Astilbin, a flavonoid compound isolated from the rhizome of Smilax glabra Roxb, displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities.

S3871

Muscone

Muscone, a flavouring ingredient, is an organic compound that is the primary contributor to the odor of musk and also a potent anti-inflammatory agent.

S3837

Echinocystic acid

Echinocystic acid (EA), a natural triterpone enriched in various herbs, displays a range of pharmacological activities including anti-inflammatory and antioxidant effects.

S3893

Bornyl acetate

Bornyl acetate, the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic.

S3824

Quercitrin

Quercitrin (3-rhamnosyl quercetin), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities.

S3827

Royal jelly acid

Royal jelly acid is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysaccharide (LPS)- and interferon (IFN)-γ-stimulated macrophage responses, inhibition of T-cell proliferation and anti-rheumatoid activity.

S3841

Eleutheroside B

Eleutheroside B (syringin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties.

S3761

Eucalyptol

Eucalyptol is a natural organic compound which controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition.

S3956

Tetramethylpyrazine

Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.

S3614

Lupeol

Lupeol is a significant lupane-type triterpene represented in the plant, fungi and animal kingdoms with anticancer, antiprotozoal, chemopreventive and anti-inflammatory properties.

S3685

4-Biphenylacetic acid

4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.

S3680

NLRP3 Inflammasome Inhibitor I

NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.

S3745

Balsalazide disodium

Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine.

S3648

Amlexanox

Amlexanox is an anti-inflammatory antiallergic immunomodulator and also an inhibitor of the protein kinases TBK1 and IKK-ε.

S3726

Selexipag

Selexipag is an orally active, first-in-class, selective prostacyclin IP receptor agonist with Ki value of 260 nM for human IP, whereas Ki values > 10,000 nM are measured at the other human G-protein-coupled prostanoid receptors (EP1-4, DP, FP and TP).

S3668

Thymopentin

Thymopentin has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells.

A2009

Rituximab

Rituximab is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM, MW: 143.86 KD.

S3622

Diammonium Glycyrrhizinate

Diammonium glycyrrhizinate (DG), a traditional Chinese medicine (TCM), is extracted and purified from liquorices (Radix glycyrrhizae). It is known for its anti-inflammatory effects, resistance to biologic oxidation and membranous protection. DG is able to reduce inflammatory injury via suppression of NF‑κB, TNF‑α and intercellular adhesion molecule 1.

S3608

Demethylzeylasteral (T-96)

Demethylzeylasteral (T-96), the active component isolated from Tripterygium wilfordii Hook F., inhibits UDP-glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects.

S1407

Bimatoprost

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

S1439

Tranilast

Tranilast is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

S1737

Prednisolone

Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.

S1622

Prednisone

Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

S4169

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.

S2413

Geniposidic acid

Geniposidic acid is an iridoid glucoside, used to treat inflammation, jaundice and hepatic disorders.

S1508

Alprostadil

Alprostadil is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.

S1733

Methylprednisolone

Methylprednisolone is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation.

S1939

(-)-Tetramisole

(-)-Tetramisole is an inhibitor of alkaline phosphatase, used as an anthelmintic.

S2787

Laquinimod

Laquinimod is a potent immunomodulator. Phase 3.

S1681

Mesalamine

Mesalamine is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.

S2910

Tempol

Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.

S1679

Flurbiprofen

Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).

S1829

Pranlukast

Pranlukast is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.

S1514

Cyclosporine

Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.

S1576

Sulfasalazine

Sulfasalazine is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis.

S1654

Phenylbutazone

Phenylbutazone is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.

S2512

Tenoxicam

Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM.

S3062

Diclofenac Potassium

Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

S7515

VGX-1027

VGX-1027 is an orally active immunomodulator. Phase 1.

S4098

Halcinonide

Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.

S1823

Fenoprofen Calcium

Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.

S8301

AS101

AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.

S4268

Flufenamic acid

Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.

S4529

Idramantone

Idramantone is an immune agonist.

S7211

PF-04418948

PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1.

S8559

INF39

INF39 is a nontoxic, irreversible NLRP3 inhibitor that counteracts NLRP3 activation through direct irreversible interaction with NLRP3 and partial inhibition of LPS-driven pro-inflammatory gene expression.

S4152

Ethamsylate

Ethamsylate is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.

S2383

Gastrodin

Gastrodin, an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.

S2387

Lappaconite HBr

Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.

S4165

Benzydamine HCl

Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.

S4170

Coumarin

Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.

S7809

MCC950(CP-456773)

MCC950 sodium salt is a potent, selective inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs; but not the AIM2, NLRC4 or NLRP1 inflammasomes.

S2400

Rheic Acid

Rhein (Monorhein; NSC 38629; Rheic acid; Rheinic acid) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities.

S4188

Sasapyrine

Sasapyrine (salsalate) is a nonsteroidal oral anti-inflammatory agent.

S7448

CORM-3

CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.

S4682

Loxoprofen

Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.

S8291

Atractylenolide I

Atractylenolide I is the major sesquiterpenoid of the rhizome of A. macrocephala and shows a wide spectrum of pharmacological activities such as antiinflammatory, digestion promoting, and antioxidant effects.

S7516

Y-320

Y-320 is an orally active immunomodulator, and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM.

S8141

Cl-amidine

Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively.

S3027

Fenoprofen calcium hydrate

Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).

S8522

Compstatin

Compstatin binds to complement component C3 and inhibits complement activation with IC50 of 12 μM.

S4753

Ganoderic acid A

Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities.

A2001

Ipilimumab

Ipilimumab is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. MW : 148 kD.

S4706

Eugenol

Eugenol is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.

S8097

C-DIM12

C-DIM12 is Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells.

S4709

Latanoprost

Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.

S2350

Rutin

Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.

S3106

Pidotimod

Pidotimod is an immunostimulant.

S4515

Ademetionine disulfate tosylate

Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.

S7434

TAPI-1

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.

S4690

Escin

Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).

S4524

2-Ethoxybenzamide

2-Ethoxybenzamide is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.