Immunology & Inflammation related

阻害剤の選択性比較
溶解度

カタログ番号	製品カタログ	溶解度(25°C)
カタログ番号	製品カタログ	水	DMSO	アルコール
S2286	Cyclosporin A	<1 mg/mL	100 mg/mL	100 mg/mL
S5004	Pimecrolimus	<1 mg/mL	100 mg/mL	100 mg/mL
S1211	Imiquimod	<1 mg/mL	1 mg/mL	<1 mg/mL
S3032	Bindarit	<1 mg/mL	64 mg/mL	64 mg/mL
S1407	Bimatoprost	<1 mg/mL	36 mg/mL	83 mg/mL
S3982	Batyl alcohol	-1 mg/mL	68 mg/mL	-1 mg/mL
S3906	Astragalus polyphenols	-1 mg/mL	81 mg/mL	-1 mg/mL
S3877	Lysionotin	-1 mg/mL	68 mg/mL	-1 mg/mL
S3881	Scopoletin	-1 mg/mL	38 mg/mL	-1 mg/mL
S3778	Patchouli alcohol	-1 mg/mL	44 mg/mL	-1 mg/mL
S3790	Methyl gallate	-1 mg/mL	36 mg/mL	-1 mg/mL
S3799	Gentisic acid	-1 mg/mL	30 mg/mL	-1 mg/mL
S3765	Picroside II	-1 mg/mL	100 mg/mL	-1 mg/mL
S3892	Isopsoralen	-1 mg/mL	14 mg/mL	-1 mg/mL
S3774	Dehydroandrographolide Succinate Potasium Salt	-1 mg/mL	10 mg/mL	-1 mg/mL
S3775	Ligustrazine hydrochloride	-1 mg/mL	34 mg/mL	-1 mg/mL
S3758	Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride	-1 mg/mL	73 mg/mL	-1 mg/mL
S3932	Astilbin	-1 mg/mL	100 mg/mL	-1 mg/mL
S3837	Echinocystic acid	-1 mg/mL	94 mg/mL	-1 mg/mL
S3827	Royal jelly acid	-1 mg/mL	37 mg/mL	-1 mg/mL
S3841	Eleutheroside B	-1 mg/mL	74 mg/mL	-1 mg/mL
S3956	Tetramethylpyrazine	-1 mg/mL	27 mg/mL	-1 mg/mL
S3614	Lupeol	<1 mg/mL	1 mg/mL	<1 mg/mL
S3685	4-Biphenylacetic acid	<1 mg/mL	42 mg/mL	42 mg/mL
S3680	NLRP3 Inflammasome Inhibitor I	<1 mg/mL	73 mg/mL	<1 mg/mL
S3745	Balsalazide disodium	87 mg/mL	87 mg/mL	<1 mg/mL
S3648	Amlexanox	<1 mg/mL	59 mg/mL	1 mg/mL
S3726	Selexipag	<1 mg/mL	99 mg/mL	49 mg/mL
S3668	Thymopentin	100 mg/mL	100 mg/mL	<1 mg/mL
S3622	Diammonium Glycyrrhizinate	100 mg/mL	100 mg/mL	<1 mg/mL
S3608	Demethylzeylasteral (T-96)	<1 mg/mL	96 mg/mL	33 mg/mL
S4753	Ganoderic acid A	<1 mg/mL	100 mg/mL	100 mg/mL
S8522	Compstatin	100 mg/mL	-1 mg/mL	-1 mg/mL
S8141	Cl-amidine	70 mg/mL	84 mg/mL	84 mg/mL
S1439	Tranilast	<1 mg/mL	66 mg/mL	<1 mg/mL
S1737	Prednisolone	<1 mg/mL	72 mg/mL	10 mg/mL
S1622	Prednisone	<1 mg/mL	71 mg/mL	<1 mg/mL
S4169	Teriflunomide	<1 mg/mL	32 mg/mL	,1 mg/mL
S2413	Geniposidic acid	<1 mg/mL	16 mg/mL	2 mg/mL
S1508	Alprostadil	<1 mg/mL	71 mg/mL	71 mg/mL
S1733	Methylprednisolone	<1 mg/mL	75 mg/mL	2 mg/mL
S1939	(-)-Tetramisole	48 mg/mL	<1 mg/mL	<1 mg/mL
S2787	Laquinimod	<1 mg/mL	61 mg/mL	1 mg/mL
S1681	Mesalamine	<1 mg/mL	31 mg/mL	31 mg/mL
S2910	Tempol	34 mg/mL	34 mg/mL	34 mg/mL
S1679	Flurbiprofen	<1 mg/mL	49 mg/mL	49 mg/mL
S1829	Pranlukast	<1 mg/mL	11 mg/mL	<1 mg/mL
S1514	Cyclosporine	<1 mg/mL	100 mg/mL	100 mg/mL
S1576	Sulfasalazine	<1 mg/mL	80 mg/mL	<1 mg/mL
S1654	Phenylbutazone	<1 mg/mL	62 mg/mL	62 mg/mL
S2512	Tenoxicam	<1 mg/mL	68 mg/mL	<1 mg/mL
S3062	Diclofenac Potassium	10 mg/mL	69 mg/mL	<1 mg/mL
S7515	VGX-1027	<1 mg/mL	41 mg/mL	41 mg/mL
S4098	Halcinonide	<1 mg/mL	90 mg/mL	4 mg/mL
S1823	Fenoprofen Calcium	<1 mg/mL	105 mg/mL	10 mg/mL
S8301	AS101	<1 mg/mL	62 mg/mL	<1 mg/mL
S4268	Flufenamic acid	<1 mg/mL	56 mg/mL	56 mg/mL
S4529	Idramantone	33 mg/mL	33 mg/mL	33 mg/mL
S7211	PF-04418948	<1 mg/mL	81 mg/mL	<1 mg/mL
S4152	Ethamsylate	53 mg/mL	53 mg/mL	<1 mg/mL
S4165	Benzydamine HCl	69 mg/mL	69 mg/mL	69 mg/mL
S4170	Coumarin	<1 mg/mL	29 mg/mL	29 mg/mL
S7809		85 mg/mL	<1 mg/mL	40 mg/mL
S2400	Rheic Acid	<1 mg/mL	<1 mg/mL	<1 mg/mL
S4188	Sasapyrine	<1 mg/mL	52 mg/mL	52 mg/mL
S7448	CORM-3	<1 mg/mL	38 mg/mL	<1 mg/mL
S4682	Loxoprofen	<1 mg/mL	49 mg/mL	49 mg/mL
S8291	Atractylenolide I	<1 mg/mL	46 mg/mL	46 mg/mL
S7516	Y-320	<1 mg/mL	11 mg/mL	<1 mg/mL
S3027	Fenoprofen calcium hydrate	<1 mg/mL	48 mg/mL	18 mg/mL
S8097	C-DIM12	<1 mg/mL	71 mg/mL	71 mg/mL
S2350	Rutin	<1 mg/mL	100 mg/mL	2 mg/mL
S7434	TAPI-1	60 mg/mL	99 mg/mL	99 mg/mL
S4690	Escin	<1 mg/mL	66 mg/mL	<1 mg/mL

Immunology & Inflammation related阻害剤(85)
新Immunology & Inflammation related製品

製品コード	製品説明	文献中の使用例	お客様のフィードバック
S2286	Cyclosporin A Cyclosporin A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.	Oncogene, 2015, 10.1038/onc.2015.32 Antiviral Res, 2015, 120:140-6 Drug metab dispos, 2013, 42(3):318-22	CsA and FTY720 suppress HFD-induced hepatic fat accumulation. Mice were sacrificed at the end of experiment and liver samples were freshly collected and processed. (a) Representative images of liver samples with H&E staining. (b) Representative images of liver samples with Oil Red O staining. Scale bars represent 100 µm.
S5004	Pimecrolimus Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12 (FKBP-12); a calcineurin inhibitor.	Mol Pharmaco, 2013, 84(1):104-13 Am J Physiol Heart Circ Physiol, 2013, 305(11):H1646-57	Pim inhibits nuclear factor of activated T-cell (NFAT) translocation of cultured human vascular smooth muscle cells. hCASM expressing green fluorescent protein-NFAT were incubated with 10 uM Pim for 30 min. Left: mean nuclear/cytosol fluorescence intensity ratio (±SE) is displayed at basal conditions and after stimulation with 500 uM ATP in the absence and presence of Pim.
S1211	Imiquimod Imiquimod is a novel synthetic agent with immune response modifying activity.
S3032	Bindarit Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.	Neurobiol Dis, 2014, 71C:292-304 Am J Transl Res, 2016, 8(1):28-36	Differential participation of ATRs or MCP-1/CCR2 signaling in RVLM in pressor response and tachycardia after stroke. Changes in mean diastolic (ΔDBP) blood pressure or heart rate (ΔHR) relative to baseline in rats that received pretreatment by microinjection bilaterally into the RVLM of bindarit (Bin; 10 nmol, MCP-1 synthesis inhibitor), BMS CCR2 22 (BMS; 10 pmol, CCR2 antagonist), propagermanium (Prop; 10 pmol, CCR2 antagonist) or vehicle control (Veh).Values are mean ± SEM, n = 5-7 animals per experimental group. *P < 0.05 versus SC group, and +P < 0.05 versus Veh (Saline) + MCAO group in the post hoc Scheffe multiple-range test.
S1407	Bimatoprost Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
S3997^新	Oxaceprol Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.
S4789^新	5-Acetylsalicylic acid 5-Acetylsalicylic acid, also known as Mesalazine or Mesalamine, is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease.
S3982^新	Batyl alcohol Batyl alcohol, isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
S3906^新	Astragalus polyphenols Astragalus is a wonderful immune enhancing herb that has strong anti-viral activity and produces extra interferon in the body. It contains rich polyphenol with various effects including antioxidant and antiinflammatory actions.
S3877^新	Lysionotin Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.
S3881^新	Scopoletin Scopoletin is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.
S3813^新	Bakuchiol Bakuchiol is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has anti-inflammatory and antimicrobial activities.
S3778^新	Patchouli alcohol Patchouli alcohol, an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S3790^新	Methyl gallate Methyl Gallate is a plant polyphenol with antioxidant, anticancer, and anti-inflammatory activities.
S3799^新	Gentisic acid Gentisic acid, an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.
S3765^新	Picroside II Picroside II is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
S3892^新	Isopsoralen Isopsoralen, also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses.
S3774^新	Dehydroandrographolide Succinate Potasium Salt Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.
S3775^新	Ligustrazine hydrochloride Tetramethylpyrazine, also known as ligustrazine, is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S3758^新	Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride Sinomenine (SN), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.
S3932^新	Astilbin Astilbin, a flavonoid compound isolated from the rhizome of Smilax glabra Roxb, displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities.
S3871^新	Muscone Muscone, a flavouring ingredient, is an organic compound that is the primary contributor to the odor of musk and also a potent anti-inflammatory agent.
S3837^新	Echinocystic acid Echinocystic acid (EA), a natural triterpone enriched in various herbs, displays a range of pharmacological activities including anti-inflammatory and antioxidant effects.
S3893^新	Bornyl acetate Bornyl acetate, the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic.
S3827^新	Royal jelly acid Royal jelly acid is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysaccharide (LPS)- and interferon (IFN)-γ-stimulated macrophage responses, inhibition of T-cell proliferation and anti-rheumatoid activity.
S3841^新	Eleutheroside B Eleutheroside B (syringin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties.
S3956^新	Tetramethylpyrazine Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S3614^新	Lupeol Lupeol is a significant lupane-type triterpene represented in the plant, fungi and animal kingdoms with anticancer, antiprotozoal, chemopreventive and anti-inflammatory properties.
S3685^新	4-Biphenylacetic acid 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.
S3680^新	NLRP3 Inflammasome Inhibitor I NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.
S3745^新	Balsalazide disodium Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine.
S3648^新	Amlexanox Amlexanox is an anti-inflammatory antiallergic immunomodulator and also an inhibitor of the protein kinases TBK1 and IKK-ε.
S3726^新	Selexipag Selexipag is an orally active, first-in-class, selective prostacyclin IP receptor agonist with Ki value of 260 nM for human IP, whereas Ki values > 10,000 nM are measured at the other human G-protein-coupled prostanoid receptors (EP1-4, DP, FP and TP).
S3668^新	Thymopentin Thymopentin has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells.
A2009^新	Rituximab Rituximab is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM, MW: 143.86 KD.
S3622^新	Diammonium Glycyrrhizinate Diammonium glycyrrhizinate (DG), a traditional Chinese medicine (TCM), is extracted and purified from liquorices (Radix glycyrrhizae). It is known for its anti-inflammatory effects, resistance to biologic oxidation and membranous protection. DG is able to reduce inflammatory injury via suppression of NF‑κB, TNF‑α and intercellular adhesion molecule 1.
S3608^新	Demethylzeylasteral (T-96) Demethylzeylasteral (T-96), the active component isolated from Tripterygium wilfordii Hook F., inhibits UDP-glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects.
S8559^新	INF39 INF39 is a nontoxic, irreversible NLRP3 inhibitor that counteracts NLRP3 activation through direct irreversible interaction with NLRP3 and partial inhibition of LPS-driven pro-inflammatory gene expression.
A2001^新	Ipilimumab Ipilimumab is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. MW : 148 kD.
S4753^新	Ganoderic acid A Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities.
S8522^新	Compstatin Compstatin binds to complement component C3 and inhibits complement activation with IC50 of 12 μM.
S8141^新	Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively.
S1439	Tranilast Tranilast is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.	Environ Toxicol Pharmacol, 2015, 39(1):114-24	Cells were cultured in LD collagen gels ± vehicle control (V), 100 M DFOM (D) or tranilast (T) for 24h (E-H) and assessed for P450 enzyme production.
S1737	Prednisolone Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.	J Pharmacol Exp Ther, 2014, 350(3):646-56 PLoS One, 2014, 9(12):e111840 Leuk Lymphoma, 2014, 55(5):1144-50	Combinations of EPZ-6438 with Prednisolone or Dexamethasone in DOHH2 EZH2 wild-type GCB lymphoma cell lines. All dose response plots were generated in Graphpad Prism and curves fitted to a four-parameter model with variable slope (2 biological replicates). Doses of EPZ-6438 ranged from 15.6-1000 nM, doses of Prednisolone ranged from 7.8–1000 nM, and doses of Dexamethasone ranged from 0.8-100 nM. The potency of Prednisolone is increased with addition of EPZ-6438 in DOHH2 cells.
S1622	Prednisone Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.
S4169	Teriflunomide Teriflunomide is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.
S2413	Geniposidic acid Geniposidic acid is an iridoid glucoside, used to treat inflammation, jaundice and hepatic disorders.
S1508	Alprostadil Alprostadil is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.
S1733	Methylprednisolone Methylprednisolone is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation.	Trop J Pharm Res, 2014, 13 (1): 53-59	Motor disturbances of the rat hindlimbs after SCI, using an inclined plane test. Key: ◇ = PBS group; ■ = Sal B group; ▲ = methylprednisolone group.
S1939	(-)-Tetramisole (-)-Tetramisole is an inhibitor of alkaline phosphatase, used as an anthelmintic.
S2787	Laquinimod Laquinimod is a potent immunomodulator. Phase 3.
S1681	Mesalamine Mesalamine is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.
S2910	Tempol Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.
S1679	Flurbiprofen Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).
S1829	Pranlukast Pranlukast is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.
S1514	Cyclosporine Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
S1576	Sulfasalazine Sulfasalazine is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis.
S1654	Phenylbutazone Phenylbutazone is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.
S2512	Tenoxicam Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM.
S3062	Diclofenac Potassium Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
S7515	VGX-1027 VGX-1027 is an orally active immunomodulator. Phase 1.
S4098	Halcinonide Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.
S1823	Fenoprofen Calcium Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
S8301	AS101 AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
S4268	Flufenamic acid Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.
S4529	Idramantone Idramantone is an immune agonist.
S7211	PF-04418948 PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1.
S4152	Ethamsylate Ethamsylate is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.
S4165	Benzydamine HCl Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.
S4170	Coumarin Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.
S7809	MCC950 sodium salt is a potent, selective inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs; but not the AIM2, NLRC4 or NLRP1 inflammasomes.	Arthritis Rheumatol, 2017, 69(8):1636-1646	A-C, Expression of caspase 1 and its active form caspase 1-p20, as demonstrated in representative Western blots (top) and the relative expression levels (B and C) in each group.
S2400	Rheic Acid Rhein (Monorhein; NSC 38629; Rheic acid; Rheinic acid) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities.
S4188	Sasapyrine Sasapyrine (salsalate) is a nonsteroidal oral anti-inflammatory agent.
S7448	CORM-3 CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
S4682	Loxoprofen Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.
S8291	Atractylenolide I Atractylenolide I is the major sesquiterpenoid of the rhizome of A. macrocephala and shows a wide spectrum of pharmacological activities such as antiinflammatory, digestion promoting, and antioxidant effects.
S7516	Y-320 Y-320 is an orally active immunomodulator, and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM.
S3027	Fenoprofen calcium hydrate Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).
S4706	Eugenol Eugenol is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.
S8097	C-DIM12 C-DIM12 is Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells.
S4709	Latanoprost Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.
S2350	Rutin Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.
S7434	TAPI-1 TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.	Sci Rep, 2017, 7:46315 PLoS One, 2017, 12(3):e0173240	(B) Florescent images of EpEX (green) and EpICD (red) in PK-15 cells, which were transfected by pSIN-fEpCAM-mCherry and treated with or without TAPI-1/DAPT. Nuclei were stained by Hoechst 33342 (blue). Scale bar, 25 μm.
S4690	Escin Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).
S4524	2-Ethoxybenzamide 2-Ethoxybenzamide is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.

研究分野別

製品類型

Immunology & Inflammation related