ACE

阻害剤の選択性比較

カタログ番号	製品カタログ	溶解度(25°C)
カタログ番号	製品カタログ	水	DMSO	アルコール
S1793	Ramipril	<1 mg/mL	83 mg/mL	83 mg/mL
S1941	Enalapril Maleate	<1 mg/mL	99 mg/mL	4 mg/mL
S2051	Captopril	2 mg/mL	43 mg/mL	43 mg/mL
S2076	Lisinopril dihydrate	20 mg/mL	<1 mg/mL	<1 mg/mL
S8940	MLN-4760	86 mg/mL	<1 mg/mL	'''10 mg/mL
S2079	Moexipril HCl	<1 mg/mL	20 mg/mL	<1 mg/mL
S2099	Temocapril HCl	<1 mg/mL	103 mg/mL	103 mg/mL
S2100	Temocapril	<1 mg/mL	95 mg/mL	95 mg/mL
S2109	Imidapril HCl	54 mg/mL	88 mg/mL	29 mg/mL
S3981	Sinapinic Acid	<1 mg/mL	44 mg/mL	44 mg/mL
S5728	Delapril Hydrochloride	<1 mg/mL	98 mg/mL	25 mg/mL
S6468	Trandolapril	<1 mg/mL	86 mg/mL	43 mg/mL
S2095	Fosinopril Sodium	117 mg/mL	<1 mg/mL	4 mg/mL
S1733	Methylprednisolone	<1 mg/mL	75 mg/mL	2 mg/mL
S4104	Diminazene Aceturate	100 mg/mL	19 mg/mL	<1 mg/mL
S5973	Methylprednisolone Acetate	<1 mg/mL	86 mg/mL	''<1 mg/mL

ACE製品

All (16) ACE阻害剤(13) ACE活性剤(2) ACE作動薬(1)

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1793	Ramipril Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
S1941	Enalapril Maleate Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
S2051	Captopril Captopril (SQ 14225) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.	Drug Metab Dispos, 2020, 48(8):613-621 J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S2076	Lisinopril dihydrate Lisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.
S8940^新	MLN-4760 MLN-4760 (compound 16) is a potent and selective inhibitor of human angiotensin-converting enzyme 2 (ACE2) with IC50 of 0.44 nM. MLN-4760 also inhibits bovine carboxypeptidase A (CPDA) with IC50 of 27 μM.
S2079	Moexipril HCl Moexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.
S2099	Temocapril HCl Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.	Cancer Cell Int, 2020, 19;20:58 Hum Cell, 2020, 10.1007/s13577-020-00420-z Hum Cell, 2020, 10.1007/s13577-020-00425-8
S2100	Temocapril Temocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
S2109	Imidapril HCl Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
S3981	Sinapinic Acid Sinapinic acid (Sinapic acid) is a small naturally occurring hydroxycinnamic acid which belongs to phenylpropanoid family and commonly used as matrix in MALDI mass spectrometry. Sinapinic acid (Sinapic acid) acts as an inhibitor of HDAC, with IC50 of 2.27 mM, and also inhibits ACE-I activity.
S5728	Delapril Hydrochloride Delapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
S6468	Trandolapril Trandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.
S2095	Fosinopril Sodium Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
S1733	Methylprednisolone Methylprednisolone (NSC-19987) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.	Drug Test Anal, 2020, 10.1002/dta.2917 Nat Med, 2017, 23(4):424-428 Trop J Pharm Res, 2014, 13 (1): 53-59	Motor disturbances of the rat hindlimbs after SCI, using an inclined plane test. Key: ◇ = PBS group; ■ = Sal B group; ▲ = methylprednisolone group.
S4104	Diminazene Aceturate Diminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent.	Am J Physiol Lung Cell Mol Physiol, 2020, 10.1152/ajplung.00025.2020
S5973^新	Methylprednisolone Acetate Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.

製品コード	製品説明	文献中Selleckの製品使用例
S1793	Ramipril Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
S1941	Enalapril Maleate Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
S2051	Captopril Captopril (SQ 14225) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.	Drug Metab Dispos, 2020, 48(8):613-621 J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S2076	Lisinopril dihydrate Lisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.
S8940^新	MLN-4760 MLN-4760 (compound 16) is a potent and selective inhibitor of human angiotensin-converting enzyme 2 (ACE2) with IC50 of 0.44 nM. MLN-4760 also inhibits bovine carboxypeptidase A (CPDA) with IC50 of 27 μM.
S2079	Moexipril HCl Moexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.
S2099	Temocapril HCl Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.	Cancer Cell Int, 2020, 19;20:58 Hum Cell, 2020, 10.1007/s13577-020-00420-z Hum Cell, 2020, 10.1007/s13577-020-00425-8
S2100	Temocapril Temocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
S2109	Imidapril HCl Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
S3981	Sinapinic Acid Sinapinic acid (Sinapic acid) is a small naturally occurring hydroxycinnamic acid which belongs to phenylpropanoid family and commonly used as matrix in MALDI mass spectrometry. Sinapinic acid (Sinapic acid) acts as an inhibitor of HDAC, with IC50 of 2.27 mM, and also inhibits ACE-I activity.
S5728	Delapril Hydrochloride Delapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
S6468	Trandolapril Trandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.
S2095	Fosinopril Sodium Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1733	Methylprednisolone Methylprednisolone (NSC-19987) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.	Drug Test Anal, 2020, 10.1002/dta.2917 Nat Med, 2017, 23(4):424-428 Trop J Pharm Res, 2014, 13 (1): 53-59	Motor disturbances of the rat hindlimbs after SCI, using an inclined plane test. Key: ◇ = PBS group; ■ = Sal B group; ▲ = methylprednisolone group.
S4104	Diminazene Aceturate Diminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent.	Am J Physiol Lung Cell Mol Physiol, 2020, 10.1152/ajplung.00025.2020

製品コード

製品説明

文献中Selleckの製品使用例

お客様のフィードバック

S1733

Methylprednisolone

Methylprednisolone (NSC-19987) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.

Drug Test Anal, 2020, 10.1002/dta.2917

Nat Med, 2017, 23(4):424-428

Trop J Pharm Res, 2014, 13 (1): 53-59

S4104

Diminazene Aceturate

Diminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent.

Am J Physiol Lung Cell Mol Physiol, 2020, 10.1152/ajplung.00025.2020

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S5973^新	Methylprednisolone Acetate Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.

製品コード

製品説明

文献中Selleckの製品使用例

お客様のフィードバック

S5973^新

Methylprednisolone Acetate

Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.

研究分野別

製品類型

ACE

阻害剤の選択性比較

ACE製品

Ramipril

Enalapril Maleate

Captopril

Lisinopril dihydrate

MLN-4760

Moexipril HCl

Temocapril HCl

Temocapril

Imidapril HCl

Sinapinic Acid

Delapril Hydrochloride

Trandolapril

Fosinopril Sodium