ACE
阻害剤の選択性比較
| カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
|---|---|---|---|---|
| 水 | DMSO | アルコール | ||
| S1793 | Ramipril | <1 mg/mL | 83 mg/mL | 83 mg/mL |
| S1941 | Enalapril Maleate | <1 mg/mL | 99 mg/mL | 4 mg/mL |
| S2051 | Captopril | 2 mg/mL | 43 mg/mL | 43 mg/mL |
| S2076 | Lisinopril dihydrate | 20 mg/mL | <1 mg/mL | <1 mg/mL |
| S8940 | MLN-4760 | 86 mg/mL | <1 mg/mL | '''10 mg/mL |
| S2079 | Moexipril HCl | <1 mg/mL | 20 mg/mL | <1 mg/mL |
| S2099 | Temocapril HCl | <1 mg/mL | 103 mg/mL | 103 mg/mL |
| S2100 | Temocapril | <1 mg/mL | 95 mg/mL | 95 mg/mL |
| S2109 | Imidapril HCl | 54 mg/mL | 88 mg/mL | 29 mg/mL |
| S3981 | Sinapinic Acid | <1 mg/mL | 44 mg/mL | 44 mg/mL |
| S5728 | Delapril Hydrochloride | <1 mg/mL | 98 mg/mL | 25 mg/mL |
| S6468 | Trandolapril | <1 mg/mL | 86 mg/mL | 43 mg/mL |
| S2095 | Fosinopril Sodium | 117 mg/mL | <1 mg/mL | 4 mg/mL |
| S1733 | Methylprednisolone | <1 mg/mL | 75 mg/mL | 2 mg/mL |
| S4104 | Diminazene Aceturate | 100 mg/mL | 19 mg/mL | <1 mg/mL |
ACE製品
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S1793 |
RamiprilRamipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM. |
||
| S1941 |
Enalapril MaleateEnalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure. |
||
| S2051 |
CaptoprilCaptopril (SQ 14225) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. |
||
| S2076 |
Lisinopril dihydrateLisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. |
||
| S8940新 |
MLN-4760MLN-4760 (compound 16) is a potent and selective inhibitor of human angiotensin-converting enzyme 2 (ACE2) with IC50 of 0.44 nM. MLN-4760 also inhibits bovine carboxypeptidase A (CPDA) with IC50 of 27 μM. |
||
| S2079 |
Moexipril HClMoexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure. |
||
| S2099 |
Temocapril HClTemocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
| S2100 |
TemocaprilTemocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
| S2109 |
Imidapril HClImidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. |
||
| S3981 |
Sinapinic AcidSinapinic acid (Sinapic acid) is a small naturally occurring hydroxycinnamic acid which belongs to phenylpropanoid family and commonly used as matrix in MALDI mass spectrometry. Sinapinic acid (Sinapic acid) acts as an inhibitor of HDAC, with IC50 of 2.27 mM, and also inhibits ACE-I activity. |
||
| S5728 |
Delapril HydrochlorideDelapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
||
| S6468 |
TrandolaprilTrandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat. |
||
| S2095 |
Fosinopril SodiumFosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure. |
||
| S1733 |
MethylprednisoloneMethylprednisolone (NSC-19987) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis. |
Motor disturbances of the rat hindlimbs after SCI, using an inclined plane test. Key: ◇ = PBS group; ■ = Sal B group; ▲ = methylprednisolone group.
|
|
| S4104 |
Diminazene AceturateDiminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S1793 |
RamiprilRamipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM. |
||
| S1941 |
Enalapril MaleateEnalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure. |
||
| S2051 |
CaptoprilCaptopril (SQ 14225) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. |
||
| S2076 |
Lisinopril dihydrateLisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. |
||
| S8940新 |
MLN-4760MLN-4760 (compound 16) is a potent and selective inhibitor of human angiotensin-converting enzyme 2 (ACE2) with IC50 of 0.44 nM. MLN-4760 also inhibits bovine carboxypeptidase A (CPDA) with IC50 of 27 μM. |
||
| S2079 |
Moexipril HClMoexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure. |
||
| S2099 |
Temocapril HClTemocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
| S2100 |
TemocaprilTemocapril (CS-622) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
||
| S2109 |
Imidapril HClImidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. |
||
| S3981 |
Sinapinic AcidSinapinic acid (Sinapic acid) is a small naturally occurring hydroxycinnamic acid which belongs to phenylpropanoid family and commonly used as matrix in MALDI mass spectrometry. Sinapinic acid (Sinapic acid) acts as an inhibitor of HDAC, with IC50 of 2.27 mM, and also inhibits ACE-I activity. |
||
| S5728 |
Delapril HydrochlorideDelapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
||
| S6468 |
TrandolaprilTrandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat. |
||
| S2095 |
Fosinopril SodiumFosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure. |
| 製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|
| S1733 |
MethylprednisoloneMethylprednisolone (NSC-19987) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis. |
2020, 10.1002/dta.2917 2017, 23(4):424-428 2014, 13 (1): 53-59 |
Motor disturbances of the rat hindlimbs after SCI, using an inclined plane test. Key: ◇ = PBS group; ■ = Sal B group; ▲ = methylprednisolone group.
|
| S4104 |
Diminazene AceturateDiminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. |
2020, 10.1152/ajplung.00025.2020 |
