Mixed Lineage Kinase

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7343 URMC-099 <1 mg/mL 84 mg/mL 6 mg/mL
S8251 Necrosulfonamide <1 mg/mL 92 mg/mL <1 mg/mL

Mixed Lineage Kinase製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7343

URMC-099

URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM.

S8251

Necrosulfonamide

Necrosulfonamide is a very specific and potent necrosis inhibitor and blocks mixed lineage kinase domain-like protein (MLKL).

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7343

URMC-099

URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM.

S8251

Necrosulfonamide

Necrosulfonamide is a very specific and potent necrosis inhibitor and blocks mixed lineage kinase domain-like protein (MLKL).

Tags: MLK Inhibitors | MLKL Review