OX受容体

シグナル伝達経路

研究分野

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7585 SB-334867 <1 mg/mL 63 mg/mL 3 mg/mL
S1545 SB408124 <1 mg/mL 36 mg/mL <1 mg/mL
S2160 Almorexant (ACT-078573) <1 mg/mL 72 mg/mL 51 mg/mL
S6717 TCS-OX2-29 <1 mg/mL 87 mg/mL 44 mg/mL
S3054 Alverine Citrate <1 mg/mL 95 mg/mL <1 mg/mL
S3880 Schisantherin A -1 mg/mL 100 mg/mL -1 mg/mL

亜型選択性的な製品

OX Receptor製品

新OX Receptor製品
製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7585

SB-334867

SB-334867 is a selective orexin-1 (OX1) receptor antagonist.

S1545

SB408124

SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.

S2160

Almorexant (ACT-078573)

Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.

S6717

TCS-OX2-29

TCX-OX2-29 is a OX2R antagonist (pKi = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (IC50s = 40 nM and >10,000 nM, respectively).

S3054

Alverine Citrate

Alverine citrate is a drug used for functional gastrointestinal disorders.

S3880

Schisantherin A

Schisantherin A, also known as Gomisin C, is a dibenzocyclooctadiene that exhibits anti-tussive, sedative, anti-inflammatory, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7585

SB-334867

SB-334867 is a selective orexin-1 (OX1) receptor antagonist.

2019, 25:2886-2895

S1545

SB408124

SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.

2017, 13(2):235-242

S2160

Almorexant (ACT-078573)

Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.

2016, 358(3):492-501

S6717

TCS-OX2-29

TCX-OX2-29 is a OX2R antagonist (pKi = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (IC50s = 40 nM and >10,000 nM, respectively).

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S3054

Alverine Citrate

Alverine citrate is a drug used for functional gastrointestinal disorders.

2018, 315(2):L133-L148

S3880

Schisantherin A

Schisantherin A, also known as Gomisin C, is a dibenzocyclooctadiene that exhibits anti-tussive, sedative, anti-inflammatory, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities.