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PAR

亜型選択性的な製品

PAR製品

  • All (9)
  • PAR阻害剤 (3)
  • PAR活性剤(1)
  • PAR拮抗剤(5)
  • 新製品
製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8067 Vorapaxar (MK-5348) Vorapaxar (SCH 530348, MK-5348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.
Basic Res Cardiol, 2023, 118(1):31
Nutrients, 2023, 15(8)1842
Nutrients, 2022, 14(22)4798
E4452New Trypsin Trypsin(Cocoonase) is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. It activates PAR2 and PAR4 and induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. It also promotes cell proliferation and differentiation and can be used in the research of wound healing and neurogenic inflammation.
S9915 FSLLRY-NH2 TFA FSLLRY-NH2 TFA (FSY-NH2) is a selective protease-activated receptor 2 (PAR2) inhibitor with an ic50 of 50 µM in PAR2-KNRK cells.
S9744 AZ3451 AZ3451 is a potent antagonist of protease-activated receptor 2 (PAR2) that binds to a remote allosteric site outside the helical bundle with IC50 of 23 nM.
S0342 Atopaxar Atopaxar(E5555,ER-172594-00) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist.
E0341 IUN76750 IUN76750 is a PAR-2 signaling pathway inhibitor.
E0102 I-191 I-191 is a potent PAR2 antagonist that inhibits multiple PAR2-induced signaling pathways and functional responses. I-191 also inhibits ERK1/2 phosphorylation, RhoA activation, and inhibition of forskolin-stimulated cAMP accumulation induced by micromolar concentrations of biased ligand GB88.
S9916 SCH79797 dihydrochloride SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist, which can inhibit binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM.
S2916 ML161 (Parmodulin 2) ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.
S9915 FSLLRY-NH2 TFA FSLLRY-NH2 TFA (FSY-NH2) is a selective protease-activated receptor 2 (PAR2) inhibitor with an ic50 of 50 µM in PAR2-KNRK cells.
E0341 IUN76750 IUN76750 is a PAR-2 signaling pathway inhibitor.
S2916 ML161 (Parmodulin 2) ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.
E4452New Trypsin Trypsin(Cocoonase) is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. It activates PAR2 and PAR4 and induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. It also promotes cell proliferation and differentiation and can be used in the research of wound healing and neurogenic inflammation.
S8067 Vorapaxar (MK-5348) Vorapaxar (SCH 530348, MK-5348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.
Basic Res Cardiol, 2023, 118(1):31
Nutrients, 2023, 15(8)1842
Nutrients, 2022, 14(22)4798
S9744 AZ3451 AZ3451 is a potent antagonist of protease-activated receptor 2 (PAR2) that binds to a remote allosteric site outside the helical bundle with IC50 of 23 nM.
S0342 Atopaxar Atopaxar(E5555,ER-172594-00) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist.
E0102 I-191 I-191 is a potent PAR2 antagonist that inhibits multiple PAR2-induced signaling pathways and functional responses. I-191 also inhibits ERK1/2 phosphorylation, RhoA activation, and inhibition of forskolin-stimulated cAMP accumulation induced by micromolar concentrations of biased ligand GB88.
S9916 SCH79797 dihydrochloride SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist, which can inhibit binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM.
E4452New Trypsin Trypsin(Cocoonase) is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. It activates PAR2 and PAR4 and induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. It also promotes cell proliferation and differentiation and can be used in the research of wound healing and neurogenic inflammation.

PAR阻害剤の選択性比較

Tags: PAR inhibitor|PAR agonist|PAR activator|PAR inducer|PAR antagonist|PAR signaling pathway|PAR assay kit