PDHK antagonist | PDHK inhibitor | PDHK agonist

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Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

抗体

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S4299	Dicoumarol	Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.	Acta Pharmacol Sin, 2023, 1-13. Anal Chem, 2023, 95(13):5661-5670 Toxicol Lett, 2023, 378:39-50
S7517	AZD7545	AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. It failed to inhibit PDHK4 at higher concentrations(>10 nM), AZD7545 stimulates PDHK4 activity.	Sci Rep, 2023, 13(1):8776 bioRxiv, 2023, 10.1101/2023.04.03.535431 bioRxiv, 2023, 2023.04.03.535431
S4299	Dicoumarol	Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.	Acta Pharmacol Sin, 2023, 1-13. Anal Chem, 2023, 95(13):5661-5670 Toxicol Lett, 2023, 378:39-50
S7517	AZD7545	AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. It failed to inhibit PDHK4 at higher concentrations(>10 nM), AZD7545 stimulates PDHK4 activity.	Sci Rep, 2023, 13(1):8776 bioRxiv, 2023, 10.1101/2023.04.03.535431 bioRxiv, 2023, 2023.04.03.535431

PDHK

PDHK製品

PDHK阻害剤の選択性比較