PTEN

PTEN製品

  • All (8)
  • PTEN阻害剤 (3)
  • PTEN活性剤(2)
  • 新製品
製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7310 SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
Oncol Rep, 2025, 54(4)125
Nat Biomed Eng, 2024, 10.1038/s41551-024-01273-9
J Biol Chem, 2024, S0021-9258(24)01808-8
SF1670-S731001W0520190329.gif
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic)) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.
Brain Behav Immun, 2025, 130:106111
Cell Death Dis, 2025, 16(1):226
Stem Cell Res Ther, 2025, 16(1):455
S8174 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Cell Commun Signal, 2025, 23(1):431
Nature, 2024, 631(8019):170-178
Aging (Albany NY), 2023, 15(6):2275-2292
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.
Environ Pollut, 2023, 323:121306
Theranostics, 2022, 12(2):910-928
J Cancer, 2021, 12(7):2140-2150
F0499 Phospho-PTEN (Ser380/Thr382/383) Antibody [K19C17] Phospho-PTEN (Ser380/Thr382/383) Rabbit mAb detects endogenous levels of PTEN when phosphorylated at Ser380, Thr382 and Thr383. It may also react with PTEN singly phosphorylated at Ser380. The antibody may also detect variants (PTEN-long/PTENα and PTENβ) at 70 kD.
F2618New Phospho-PTEN (Thr366) Antibody [A11K14]
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. Ginkgolic acid C17:1 can induce the substantial expression of PTEN and SHP-1. Ginkgolic acid C17:1 induces apoptosis of tumor cells.
F3548New PTEN Antibody [J22G2]
S7310 SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
Oncol Rep, 2025, 54(4)125
Nat Biomed Eng, 2024, 10.1038/s41551-024-01273-9
J Biol Chem, 2024, S0021-9258(24)01808-8
SF1670-S731001W0520190329.gif
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic)) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.
Brain Behav Immun, 2025, 130:106111
Cell Death Dis, 2025, 16(1):226
Stem Cell Res Ther, 2025, 16(1):455
S8174 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Cell Commun Signal, 2025, 23(1):431
Nature, 2024, 631(8019):170-178
Aging (Albany NY), 2023, 15(6):2275-2292
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.
Environ Pollut, 2023, 323:121306
Theranostics, 2022, 12(2):910-928
J Cancer, 2021, 12(7):2140-2150
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. Ginkgolic acid C17:1 can induce the substantial expression of PTEN and SHP-1. Ginkgolic acid C17:1 induces apoptosis of tumor cells.
F2618New Phospho-PTEN (Thr366) Antibody [A11K14]
F3548New PTEN Antibody [J22G2]