PTEN

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7310 SF1670 <1 mg/mL 29 mg/mL 1 mg/mL
S8651 bpV (HOpic) 69 mg/mL <1 mg/mL <1 mg/mL
S8174 VO-Ohpic trihydrate <1 mg/mL 72 mg/mL <1 mg/mL
S9190 Oroxin B -1 mg/mL 100 mg/mL -1 mg/mL

PTEN製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7310

SF1670

SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.

S8651

bpV (HOpic)

bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.

S8174

VO-Ohpic trihydrate

VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.

S9190

Oroxin B

Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7310

SF1670

SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.

S8651

bpV (HOpic)

bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.

S8174

VO-Ohpic trihydrate

VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S9190

Oroxin B

Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.