PTEN

PTEN製品

  • All (5)
  • PTEN阻害剤 (3)
  • PTEN活性剤(2)
  • 新製品
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S7310 SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
Fish Shellfish Immunol, 2024, 146:109384
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic)) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.
Protein Cell, 2023, 14(5):350-368
Adv Sci (Weinh), 2023, 10(13):e2205436
Cell Death Discov, 2023, 9(1):82
S8174 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Aging (Albany NY), 2023, 15(6):2275-2292
Stem Cell Res Ther, 2020, 11(1):140
Life Sci, 2020, 25;253:117718
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.
Environ Pollut, 2023, 323:121306
Theranostics, 2022, 12(2):910-928
J Cancer, 2021, 12(7):2140-2150
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. Ginkgolic acid C17:1 can induce the substantial expression of PTEN and SHP-1. Ginkgolic acid C17:1 induces apoptosis of tumor cells.
S7310 SF1670 SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
Fish Shellfish Immunol, 2024, 146:109384
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
eNeuro, 2023, 10(9)ENEURO.0185-23.2023
S8651 bpV (HOpic) bpV (HOpic) (Bisperoxovanadium (HOpic)) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.
Protein Cell, 2023, 14(5):350-368
Adv Sci (Weinh), 2023, 10(13):e2205436
Cell Death Discov, 2023, 9(1):82
S8174 VO-Ohpic trihydrate VO-Ohpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.
Aging (Albany NY), 2023, 15(6):2275-2292
Stem Cell Res Ther, 2020, 11(1):140
Life Sci, 2020, 25;253:117718
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels is found to be downregulated, while PTEN was upregulated after Oroxin B treatment.
Environ Pollut, 2023, 323:121306
Theranostics, 2022, 12(2):910-928
J Cancer, 2021, 12(7):2140-2150
S0918 Ginkgolic acid C17:1 Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. Ginkgolic acid C17:1 can induce the substantial expression of PTEN and SHP-1. Ginkgolic acid C17:1 induces apoptosis of tumor cells.

PTEN阻害剤の選択性比較

Tags: PTEN inhibitor|PTEN agonist|PTEN activator|PTEN inducer|PTEN antagonist|PTEN signaling pathway|PTEN assay kit